{"id":"https://openalex.org/W2912349461","doi":"https://doi.org/10.1111/pedi.12823","title":"Glibenclamide oral suspension: Suitable and effective in patients with neonatal diabetes","display_name":"Glibenclamide oral suspension: Suitable and effective in patients with neonatal diabetes","publication_year":2019,"publication_date":"2019-01-26","ids":{"openalex":"https://openalex.org/W2912349461","doi":"https://doi.org/10.1111/pedi.12823","mag":"2912349461","pmid":"https://pubmed.ncbi.nlm.nih.gov/30684309"},"language":"en","primary_location":{"id":"doi:10.1111/pedi.12823","doi":"https://doi.org/10.1111/pedi.12823","is_oa":true,"landing_page_url":"https://doi.org/10.1111/pedi.12823","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pedi.12823","source":{"id":"https://openalex.org/S118758356","display_name":"Pediatric Diabetes","issn_l":"1399-543X","issn":["1399-543X","1399-5448"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Diabetes","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pedi.12823","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087729976","display_name":"Jacques Beltrand","orcid":"https://orcid.org/0000-0002-3759-3490","observed_orcids":["https://orcid.org/0000-0002-3759-3490"]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210091437","display_name":"Sorbonne Paris Cit\u00e9","ror":"https://ror.org/001z21q04","country_code":"FR","type":"other","lineage":["https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210091437","https://openalex.org/I4210124654","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210096427","https://openalex.org/I4210124654","https://openalex.org/I4210141964","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210165077","display_name":"Institut des Maladies G\u00e9n\u00e9tiques Imagine","ror":"https://ror.org/05rq3rb55","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210100892","https://openalex.org/I4210124654","https://openalex.org/I4210165077","https://openalex.org/I48825208"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Jacques Beltrand","raw_affiliation_strings":["Centre der\u00e9f\u00e9rence national des maladies rares de la s\u00e9cr\u00e9tion d'insuline et de lasensibilit\u00e9 \u00e0 l'insuline, PRISIS, Saint\u2010Antoine hospital Paris France","Imagine Institute, Sorbonne Paris Cit\u00e9 university Paris France","Inserm U1016Cochin Institute Paris France","Paris Descartes Medical School \u2013Sorbonne Paris Cit\u00e9 university Paris France","Pediatric diabetes and endocrinologyNecker Enfants Malades Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France","NeckerEnfants Malades Hospital, EnDOrare, MTG3, Genetic disordes of glucose andinsulin homeostasis, European Reference networks, Paris, France"],"raw_orcid":"https://orcid.org/0000-0002-3759-3490","affiliations":[{"raw_affiliation_string":"Centre der\u00e9f\u00e9rence national des maladies rares de la s\u00e9cr\u00e9tion d'insuline et de lasensibilit\u00e9 \u00e0 l'insuline, PRISIS, Saint\u2010Antoine hospital Paris France","institution_ids":["https://openalex.org/I4210102928"]},{"raw_affiliation_string":"Imagine Institute, Sorbonne Paris Cit\u00e9 university Paris France","institution_ids":["https://openalex.org/I4210091437","https://openalex.org/I4210165077"]},{"raw_affiliation_string":"Inserm U1016Cochin Institute Paris France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210141964"]},{"raw_affiliation_string":"Paris Descartes Medical School \u2013Sorbonne Paris Cit\u00e9 university Paris France","institution_ids":["https://openalex.org/I4210091437"]},{"raw_affiliation_string":"Pediatric diabetes and endocrinologyNecker Enfants Malades Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"NeckerEnfants Malades Hospital, EnDOrare, MTG3, Genetic disordes of glucose andinsulin homeostasis, European Reference networks, Paris, France","institution_ids":["https://openalex.org/I1288880153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113241742","display_name":"Amandine Baptiste","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210124654","https://openalex.org/I4387156284","https://openalex.org/I48825208"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Amandine Baptiste","raw_affiliation_strings":["Clinical research unit Paris Descartes Necker Cochin, Necker Enfants Malades HospitalAssistance Publique\u2010H\u00f4pitaux de Paris Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical research unit Paris Descartes Necker Cochin, Necker Enfants Malades HospitalAssistance Publique\u2010H\u00f4pitaux de Paris Paris France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4387156284"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050007993","display_name":"Kanetee Busiah","orcid":"https://orcid.org/0000-0002-1059-0791","observed_orcids":["https://orcid.org/0000-0002-1059-0791"]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Kanetee Busiah","raw_affiliation_strings":["Pediatric diabetes and endocrinologyNecker Enfants Malades Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric diabetes and endocrinologyNecker Enfants Malades Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210097159"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089598609","display_name":"Na\u00efm Bouazza","orcid":"https://orcid.org/0000-0002-2158-1399","observed_orcids":["https://orcid.org/0000-0002-2158-1399"]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210124654","https://openalex.org/I4387156284","https://openalex.org/I48825208"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Naim Bouazza","raw_affiliation_strings":["Clinical research unit Paris Descartes Necker Cochin, Necker Enfants Malades HospitalAssistance Publique\u2010H\u00f4pitaux de Paris Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical research unit Paris Descartes Necker Cochin, Necker Enfants Malades HospitalAssistance Publique\u2010H\u00f4pitaux de Paris Paris France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4387156284"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010375628","display_name":"C\u00e9cile Godot","orcid":"https://orcid.org/0000-0001-7350-6131","observed_orcids":["https://orcid.org/0000-0001-7350-6131"]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Cecile Godot","raw_affiliation_strings":["Pediatric diabetes and endocrinologyNecker Enfants Malades Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric diabetes and endocrinologyNecker Enfants Malades Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210097159"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040902054","display_name":"Adeline Boucheron","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Adeline Boucheron","raw_affiliation_strings":["Pediatric diabetes and endocrinologyNecker Enfants Malades Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric diabetes and endocrinologyNecker Enfants Malades Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210097159"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067683186","display_name":"Zoubir Djerada","orcid":"https://orcid.org/0000-0002-4022-7889","observed_orcids":["https://orcid.org/0000-0002-4022-7889"]},"institutions":[{"id":"https://openalex.org/I4210105796","display_name":"Centre Hospitalier Universitaire de Reims","ror":"https://ror.org/01jbb3w63","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210105796"]},{"id":"https://openalex.org/I4210165259","display_name":"H\u00f4pital Maison Blanche","ror":"https://ror.org/054bptx32","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210165259"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Zoubir Djerada","raw_affiliation_strings":["CHU Reims, Maison Blanche hospitalLaboratoire de Pharmacologie \u2010Toxicologie Reims France","CHU Reims, Maison Blanche hospital, Laboratoire de Pharmacologie -Toxicologie, Reims, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHU Reims, Maison Blanche hospitalLaboratoire de Pharmacologie \u2010Toxicologie Reims France","institution_ids":["https://openalex.org/I4210105796","https://openalex.org/I4210165259"]},{"raw_affiliation_string":"CHU Reims, Maison Blanche hospital, Laboratoire de Pharmacologie -Toxicologie, Reims, France","institution_ids":["https://openalex.org/I4210105796","https://openalex.org/I4210165259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083235226","display_name":"Claire Gozalo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210105796","display_name":"Centre Hospitalier Universitaire de Reims","ror":"https://ror.org/01jbb3w63","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210105796"]},{"id":"https://openalex.org/I4210165259","display_name":"H\u00f4pital Maison Blanche","ror":"https://ror.org/054bptx32","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210165259"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Claire Gozalo","raw_affiliation_strings":["CHU Reims, Maison Blanche hospitalLaboratoire de Pharmacologie \u2010Toxicologie Reims France","CHU Reims, Maison Blanche hospital, Laboratoire de Pharmacologie -Toxicologie, Reims, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHU Reims, Maison Blanche hospitalLaboratoire de Pharmacologie \u2010Toxicologie Reims France","institution_ids":["https://openalex.org/I4210105796","https://openalex.org/I4210165259"]},{"raw_affiliation_string":"CHU Reims, Maison Blanche hospital, Laboratoire de Pharmacologie -Toxicologie, Reims, France","institution_ids":["https://openalex.org/I4210105796","https://openalex.org/I4210165259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102747446","display_name":"Marianne Berdugo","orcid":"https://orcid.org/0000-0002-4299-837X","observed_orcids":["https://orcid.org/0000-0002-4299-837X"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I40434647","https://openalex.org/I4210092322","https://openalex.org/I4210124654","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marianne Berdugo","raw_affiliation_strings":["Inserm U1138, Cordeliers research centrePierre et Marie Curie university Paris France","Inserm U1138, Cordeliers research centre, Pierre et Marie Curie university, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U1138, Cordeliers research centrePierre et Marie Curie university Paris France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210092322"]},{"raw_affiliation_string":"Inserm U1138, Cordeliers research centre, Pierre et Marie Curie university, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210092322","https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089989719","display_name":"Jean\u2010Marc Tr\u00e9luyer","orcid":"https://orcid.org/0000-0002-2045-4742","observed_orcids":["https://orcid.org/0000-0002-2045-4742"]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210091437","display_name":"Sorbonne Paris Cit\u00e9","ror":"https://ror.org/001z21q04","country_code":"FR","type":"other","lineage":["https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210091437","https://openalex.org/I4210124654","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210133078","display_name":"H\u00f4tel-Dieu de Paris","ror":"https://ror.org/03jmjy508","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210124464","https://openalex.org/I4210133078"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210124654","https://openalex.org/I4387156284","https://openalex.org/I48825208"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean\u2010Marc Tr\u00e9luyer","raw_affiliation_strings":["Clinical pharmacology unit, AP\u2010HPCochin\u2010Broca\u2010H\u00f4tel\u2010Dieu hospital Paris France","Clinical research unit Paris Descartes Necker Cochin, Necker Enfants Malades HospitalAssistance Publique\u2010H\u00f4pitaux de Paris Paris France","Paris Descartes Medical School \u2013Sorbonne Paris Cit\u00e9 university Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical pharmacology unit, AP\u2010HPCochin\u2010Broca\u2010H\u00f4tel\u2010Dieu hospital Paris France","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210133078"]},{"raw_affiliation_string":"Clinical research unit Paris Descartes Necker Cochin, Necker Enfants Malades HospitalAssistance Publique\u2010H\u00f4pitaux de Paris Paris France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4387156284"]},{"raw_affiliation_string":"Paris Descartes Medical School \u2013Sorbonne Paris Cit\u00e9 university Paris France","institution_ids":["https://openalex.org/I4210091437"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104107729","display_name":"Caroline Elie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210124654","https://openalex.org/I4387156284","https://openalex.org/I48825208"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Caroline Elie","raw_affiliation_strings":["Clinical research unit Paris Descartes Necker Cochin, Necker Enfants Malades HospitalAssistance Publique\u2010H\u00f4pitaux de Paris Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical research unit Paris Descartes Necker Cochin, Necker Enfants Malades HospitalAssistance Publique\u2010H\u00f4pitaux de Paris Paris France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4387156284"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077054564","display_name":"Michel Polak","orcid":"https://orcid.org/0000-0003-2639-352X","observed_orcids":["https://orcid.org/0000-0003-2639-352X"]},"institutions":[{"id":"https://openalex.org/I1288880153","display_name":"H\u00f4pital Necker-Enfants Malades","ror":"https://ror.org/05tr67282","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I1288880153","https://openalex.org/I4210097159","https://openalex.org/I4210120235"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210091437","display_name":"Sorbonne Paris Cit\u00e9","ror":"https://ror.org/001z21q04","country_code":"FR","type":"other","lineage":["https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210091437","https://openalex.org/I4210124654","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210096427","https://openalex.org/I4210124654","https://openalex.org/I4210141964","https://openalex.org/I48825208"]},{"id":"https://openalex.org/I4210165077","display_name":"Institut des Maladies G\u00e9n\u00e9tiques Imagine","ror":"https://ror.org/05rq3rb55","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I40434647","https://openalex.org/I4210100892","https://openalex.org/I4210124654","https://openalex.org/I4210165077","https://openalex.org/I48825208"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Michel Polak","raw_affiliation_strings":["Centre der\u00e9f\u00e9rence national des maladies rares de la s\u00e9cr\u00e9tion d'insuline et de lasensibilit\u00e9 \u00e0 l'insuline, PRISIS, Saint\u2010Antoine hospital Paris France","Imagine Institute, Sorbonne Paris Cit\u00e9 university Paris France","Inserm U1016Cochin Institute Paris France","Paris Descartes Medical School \u2013Sorbonne Paris Cit\u00e9 university Paris France","Pediatric diabetes and endocrinologyNecker Enfants Malades Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France","NeckerEnfants Malades Hospital, EnDOrare, MTG3, Genetic disordes of glucose andinsulin homeostasis, European Reference networks, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre der\u00e9f\u00e9rence national des maladies rares de la s\u00e9cr\u00e9tion d'insuline et de lasensibilit\u00e9 \u00e0 l'insuline, PRISIS, Saint\u2010Antoine hospital Paris France","institution_ids":["https://openalex.org/I4210102928"]},{"raw_affiliation_string":"Imagine Institute, Sorbonne Paris Cit\u00e9 university Paris France","institution_ids":["https://openalex.org/I4210091437","https://openalex.org/I4210165077"]},{"raw_affiliation_string":"Inserm U1016Cochin Institute Paris France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210141964"]},{"raw_affiliation_string":"Paris Descartes Medical School \u2013Sorbonne Paris Cit\u00e9 university Paris France","institution_ids":["https://openalex.org/I4210091437"]},{"raw_affiliation_string":"Pediatric diabetes and endocrinologyNecker Enfants Malades Hospital, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France","institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"NeckerEnfants Malades Hospital, EnDOrare, MTG3, Genetic disordes of glucose andinsulin homeostasis, European Reference networks, Paris, France","institution_ids":["https://openalex.org/I1288880153"]}]},{"author_position":"last","author":{"id":null,"display_name":"on behalf of the GLID\u2010KIR study group","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"on behalf of the GLID\u2010KIR study group","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5087729976"],"corresponding_institution_ids":["https://openalex.org/I1288880153","https://openalex.org/I154526488","https://openalex.org/I4210091437","https://openalex.org/I4210097159","https://openalex.org/I4210102928","https://openalex.org/I4210141964","https://openalex.org/I4210165077"],"apc_list":{"value":4300,"currency":"USD","value_usd":4300},"apc_paid":null,"fwci":1.5572,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.83379726,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"20","issue":"3","first_page":"246","last_page":"254"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.25,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.25,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.24160000681877136,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.18880000710487366,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glibenclamide","display_name":"glibenclamide","score":0.8389999866485596},{"id":"https://openalex.org/keywords/oral-suspension","display_name":"oral suspension","score":0.8450000286102295},{"id":"https://openalex.org/keywords/neonatal-diabetes-mellitus","display_name":"neonatal diabetes","score":0.9580000042915344},{"id":"https://openalex.org/keywords/potassium-channel-mutations","display_name":"potassium channel mutations","score":0.6209999918937683},{"id":"https://openalex.org/keywords/atp-sensitive-potassium-channels","display_name":"ATP-sensitive potassium channels","score":0.5690000057220459},{"id":"https://openalex.org/keywords/pediatric-diabetes-treatment","display_name":"pediatric diabetes treatment","score":0.4659999907016754},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.8360000252723694},{"id":"https://openalex.org/keywords/hypoglycemia","display_name":"hypoglycemia","score":0.9269999861717224},{"id":"https://openalex.org/keywords/hyperglycemia","display_name":"hyperglycemia","score":0.8420000076293945},{"id":"https://openalex.org/keywords/treatment-acceptability","display_name":"treatment acceptability","score":0.7689999938011169},{"id":"https://openalex.org/keywords/drug-formulation-switching","display_name":"drug formulation switching","score":0.5099999904632568},{"id":"https://openalex.org/keywords/orphan-drugs","display_name":"orphan drugs","score":0.6010000109672546}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9397144317626953},{"id":"https://openalex.org/C2779768347","wikidata":"https://www.wikidata.org/wiki/Q420626","display_name":"Glibenclamide","level":3,"score":0.8803770542144775},{"id":"https://openalex.org/C2780668416","wikidata":"https://www.wikidata.org/wiki/Q202758","display_name":"Hypoglycemia","level":3,"score":0.6139366030693054},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6092642545700073},{"id":"https://openalex.org/C2779802037","wikidata":"https://www.wikidata.org/wiki/Q40878","display_name":"Diarrhea","level":2,"score":0.4344102144241333},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3584613800048828},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.34839850664138794},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3250749409198761},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.16233044862747192}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000151","qualifier_name":"congenital","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000151","qualifier_name":"congenital","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000151","qualifier_name":"congenital","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005905","descriptor_name":"Glyburide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005905","descriptor_name":"Glyburide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005905","descriptor_name":"Glyburide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005905","descriptor_name":"Glyburide","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005905","descriptor_name":"Glyburide","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005905","descriptor_name":"Glyburide","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007004","descriptor_name":"Hypoglycemic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007232","descriptor_name":"Infant, Newborn, Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D007232","descriptor_name":"Infant, Newborn, Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D007232","descriptor_name":"Infant, Newborn, Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010342","descriptor_name":"Patient Acceptance of Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010342","descriptor_name":"Patient Acceptance of Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010342","descriptor_name":"Patient Acceptance of Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013535","descriptor_name":"Suspensions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013535","descriptor_name":"Suspensions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013535","descriptor_name":"Suspensions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013607","descriptor_name":"Tablets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013607","descriptor_name":"Tablets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013607","descriptor_name":"Tablets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/pedi.12823","doi":"https://doi.org/10.1111/pedi.12823","is_oa":true,"landing_page_url":"https://doi.org/10.1111/pedi.12823","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pedi.12823","source":{"id":"https://openalex.org/S118758356","display_name":"Pediatric Diabetes","issn_l":"1399-543X","issn":["1399-543X","1399-5448"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Diabetes","raw_type":"journal-article"},{"id":"pmid:30684309","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30684309","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric diabetes","raw_type":"Clinical Trial, Phase II"}],"best_oa_location":{"id":"doi:10.1111/pedi.12823","doi":"https://doi.org/10.1111/pedi.12823","is_oa":true,"landing_page_url":"https://doi.org/10.1111/pedi.12823","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pedi.12823","source":{"id":"https://openalex.org/S118758356","display_name":"Pediatric Diabetes","issn_l":"1399-543X","issn":["1399-543X","1399-5448"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Diabetes","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8600000143051147}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320337376","display_name":"NIH Clinical Center","ror":"https://ror.org/04vfsmv21"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2912349461.pdf","grobid_xml":"https://content.openalex.org/works/W2912349461.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1971719326","https://openalex.org/W1987534913","https://openalex.org/W2012515461","https://openalex.org/W2042553471","https://openalex.org/W2043914101","https://openalex.org/W2065039877","https://openalex.org/W2087011214","https://openalex.org/W2096869005","https://openalex.org/W2114381989","https://openalex.org/W2155078339","https://openalex.org/W2164438031","https://openalex.org/W2177721863","https://openalex.org/W2514087954"],"related_works":["https://openalex.org/W2397078474","https://openalex.org/W2015300033","https://openalex.org/W2429879170","https://openalex.org/W2411309176","https://openalex.org/W2522892154","https://openalex.org/W2165858836","https://openalex.org/W1979017002","https://openalex.org/W108838523","https://openalex.org/W3144812701","https://openalex.org/W2074488766"],"abstract_inverted_index":{"BACKGROUND:":[0],"Results":[1],"of":[2,17,24,45,134,139,141,178,186,204,233],"genetic":[3],"have":[4],"led":[5],"to":[6,157,171,219,274],"off-label":[7],"glibenclamide":[8,25,68,241],"treatment":[9],"in":[10,229,259,268,276],"patients":[11,109,119,199,235,260],"with":[12,131,194,261,270],"neonatal":[13],"diabetes":[14],"(NDM)":[15],"because":[16],"potassium":[18],"channel":[19],"mutations.":[20],"No":[21],"pediatric":[22,47,252],"form":[23],"was":[26,29,40],"available.":[27],"Glibenclamide":[28],"designated":[30],"an":[31],"orphan":[32],"drug":[33,248],"designation":[34],"for":[35,70,76,212,251],"NDM":[36,262],"and":[37,55,85,94,99,101,123,151,180,191,222,257],"a":[38,43],"suspension":[39,75,122,135,147,158,243],"developed.":[41],"As":[42],"part":[44],"the":[46,74,121,125,132,146,149,162,210,234,237,245],"plan":[48],"investigation,":[49],"we":[50],"assessed":[51,80],"its":[52],"acceptability,":[53],"efficiency,":[54],"safety.":[56],"METHODS:":[57],"In":[58],"this":[59],"Phase":[60],"II,":[61],"prospective,":[62],"non-randomized,":[63],"single-center":[64],"study,":[65],"patient":[66,86],"received":[67],"tablets":[69,150,156,218],"1":[71],"month":[72],"then":[73],"3":[77],"months.":[78],"We":[79,106],"acceptability":[81],"using":[82,89],"hedonic":[83],"scales":[84],"questionnaires,":[87],"effectiveness":[88],"glycated":[90],"hemoglobin":[91],"(HbA1C)":[92],"assays":[93,190],"safety":[95],"based":[96],"on":[97],"hypo":[98],"hyperglycemia,":[100],"other":[102],"adverse":[103],"events.":[104],"RESULTS:":[105],"included":[107],"10":[108],"(0.1-16.2":[110],"years,":[111],"6":[112,142],"<":[113],"5":[114,140],"years)":[115],"were":[116,129,182,192],"included.":[117],"Younger":[118],"preferred":[120,145],"older":[124],"tablets.":[126],"All":[127],"parents":[128,138],"satisfied":[130],"ease":[133],"administration.":[136],"The":[137,240],"younger":[143],"children":[144],"over":[148],"kept":[152],"it.":[153],"Switching":[154],"from":[155,217],"did":[159],"not":[160],"affect":[161],"excellent":[163],"metabolic":[164],"control":[165],"(median":[166],"HbA1c":[167],"change,":[168],"-0.40%,":[169],"[-1.3%":[170],"0.5%]":[172],"P":[173],"=":[174],"0.08).":[175],"Median":[176],"frequencies":[177],"hypoglycemia":[179,205],"hyperglycemia":[181],"less":[183],"than":[184],"5%":[185],"routine":[187],"blood":[188],"glucose":[189],"similar":[193],"both":[195],"dosage":[196,213],"forms.":[197],"Two":[198],"each":[200],"experienced":[201],"one":[202],"episode":[203],"below":[206],"35":[207],"mg/dL":[208],"highlighting":[209],"need":[211],"titration":[214],"when":[215],"switching":[216],"suspension.":[220],"Transient":[221],"non-severe":[223],"abdominal":[224],"pain":[225],"or":[226],"diarrhea":[227],"occurred":[228],"three":[230],"patients.":[231],"None":[232],"discontinued":[236],"treatment.":[238],"CONCLUSION:":[239],"oral":[242],"Amglidia,":[244],"first":[246],"anti-diabetic":[247],"specifically":[249],"developed":[250],"patients,":[253],"is":[254],"acceptable,":[255],"effective,":[256],"safe":[258],"(NCT02375828).":[263],"CLINICAL":[264],"TRIAL":[265],"REGISTRATION:":[266],"Glibentek":[267],"Patients":[269],"Neonatal":[271],"Diabetes":[272],"Secondary":[273],"Mutations":[275],"K":[277],"+":[278],"-ATP":[279],"Channels,":[280],"clinicaltrials.gov,":[281],"NCT02375828,":[282],"https://clinicaltrials.gov/ct2/show/NCT02375828.":[283]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":6},{"year":2020,"cited_by_count":3}],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2025-10-10T00:00:00"}