{"id":"https://openalex.org/W2911736993","doi":"https://doi.org/10.15744/2393-9060.5.303","title":"A Review on Antioxidant, Anti-Inflammatory and Gastroprotective Abilities of Mango (Magnifera indica) Leaf Extract and Mangiferin","display_name":"A Review on Antioxidant, Anti-Inflammatory and Gastroprotective Abilities of Mango (Magnifera indica) Leaf Extract and Mangiferin","publication_year":2018,"publication_date":"2018-09-01","ids":{"openalex":"https://openalex.org/W2911736993","doi":"https://doi.org/10.15744/2393-9060.5.303","mag":"2911736993"},"language":"en","primary_location":{"id":"doi:10.15744/2393-9060.5.303","doi":"https://doi.org/10.15744/2393-9060.5.303","is_oa":true,"landing_page_url":"https://doi.org/10.15744/2393-9060.5.303","pdf_url":"http://www.annexpublishers.com/articles/JNH/5303-A-Review-on-Antioxidant-Anti-Inflammatory-and-Gastroprotective-Abilities-of-Mango-Magnifera-Indica-Leaf-Extract-and-Mangiferin.pdf","source":{"id":"https://openalex.org/S4210176295","display_name":"Journal of Nutrition and Health Sciences","issn_l":"2393-9060","issn":["2393-9060"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Nutrition and Health Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://www.annexpublishers.com/articles/JNH/5303-A-Review-on-Antioxidant-Anti-Inflammatory-and-Gastroprotective-Abilities-of-Mango-Magnifera-Indica-Leaf-Extract-and-Mangiferin.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071183606","display_name":"Stohs Sj","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800482329","display_name":"CHI Health Creighton University Medical Center - Bergan Mercy","ror":"https://ror.org/03z1w3b90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800482329","https://openalex.org/I2802665030","https://openalex.org/I2802797007"]},{"id":"https://openalex.org/I44461941","display_name":"University of Houston","ror":"https://ror.org/048sx0r50","country_code":"US","type":"education","lineage":["https://openalex.org/I44461941"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stohs SJ","raw_affiliation_strings":["Cepham Research Center, Somerset, New Jersey, USA","Creighton University Medical Center, Omaha, Nebraska, USA","Departments of Pharmacological and Pharmaceutical Sciences, University of Houston College of Pharmacy, Houston, Texas, USA","The Japanese Institute for Health Food Standards, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cepham Research Center, Somerset, New Jersey, USA","institution_ids":[]},{"raw_affiliation_string":"Creighton University Medical Center, Omaha, Nebraska, USA","institution_ids":["https://openalex.org/I2800482329"]},{"raw_affiliation_string":"Departments of Pharmacological and Pharmaceutical Sciences, University of Houston College of Pharmacy, Houston, Texas, USA","institution_ids":["https://openalex.org/I44461941"]},{"raw_affiliation_string":"The Japanese Institute for Health Food Standards, Bunkyo-ku, Tokyo, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Swaroop A","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Swaroop A","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086425802","display_name":"Hiroyoshi Moriyama","orcid":"https://orcid.org/0000-0002-6074-6424","observed_orcids":["https://orcid.org/0000-0002-6074-6424"]},"institutions":[{"id":"https://openalex.org/I2800482329","display_name":"CHI Health Creighton University Medical Center - Bergan Mercy","ror":"https://ror.org/03z1w3b90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800482329","https://openalex.org/I2802665030","https://openalex.org/I2802797007"]},{"id":"https://openalex.org/I44461941","display_name":"University of Houston","ror":"https://ror.org/048sx0r50","country_code":"US","type":"education","lineage":["https://openalex.org/I44461941"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Moriyama H","raw_affiliation_strings":["Cepham Research Center, Somerset, New Jersey, USA","Creighton University Medical Center, Omaha, Nebraska, USA","Departments of Pharmacological and Pharmaceutical Sciences, University of Houston College of Pharmacy, Houston, Texas, USA","The Japanese Institute for Health Food Standards, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cepham Research Center, Somerset, New Jersey, USA","institution_ids":[]},{"raw_affiliation_string":"Creighton University Medical Center, Omaha, Nebraska, USA","institution_ids":["https://openalex.org/I2800482329"]},{"raw_affiliation_string":"Departments of Pharmacological and Pharmaceutical Sciences, University of Houston College of Pharmacy, Houston, Texas, USA","institution_ids":["https://openalex.org/I44461941"]},{"raw_affiliation_string":"The Japanese Institute for Health Food Standards, Bunkyo-ku, Tokyo, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025047849","display_name":"Manashi Bagchi","orcid":"https://orcid.org/0000-0002-1527-6419","observed_orcids":["https://orcid.org/0000-0002-1527-6419"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bagchi M","raw_affiliation_strings":["Cepham Research Center, Somerset, New Jersey, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cepham Research Center, Somerset, New Jersey, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ahmad T","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ahmad T","raw_affiliation_strings":["Cepham Research Center, Somerset, New Jersey, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cepham Research Center, Somerset, New Jersey, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019498762","display_name":"Debasis Bagchi","orcid":"https://orcid.org/0000-0001-9478-6427","observed_orcids":["https://orcid.org/0000-0001-9478-6427"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bagchi D","raw_affiliation_strings":["Cepham Research Center, Somerset, New Jersey, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cepham Research Center, Somerset, New Jersey, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5071183606"],"corresponding_institution_ids":["https://openalex.org/I2800482329","https://openalex.org/I44461941"],"apc_list":null,"apc_paid":null,"fwci":2.3091,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.86824362,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"5","issue":"3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13846","display_name":"Mangiferin and Mango Extracts","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13846","display_name":"Mangiferin and Mango Extracts","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12087","display_name":"Natural Compound Pharmacology Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mango-leaf-extract","display_name":"mango leaf extract","score":0.9229999780654907},{"id":"https://openalex.org/keywords/mango","display_name":"mango","score":0.8939999938011169},{"id":"https://openalex.org/keywords/mangiferin","display_name":"mangiferin","score":1.0},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.8040000200271606},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":1.0},{"id":"https://openalex.org/keywords/gastroprotective-effect","display_name":"gastroprotection","score":0.8479999899864197},{"id":"https://openalex.org/keywords/gut-health","display_name":"gut health","score":0.9210000038146973},{"id":"https://openalex.org/keywords/free-radical-scavenging-activity","display_name":"free radical scavenging","score":0.9129999876022339},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8109999895095825},{"id":"https://openalex.org/keywords/inducible-nitric-oxide-synthase","display_name":"inducible nitric oxide synthase","score":0.9929999709129333},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.796999990940094},{"id":"https://openalex.org/keywords/antidiabetic-activity","display_name":"antidiabetic activity","score":0.9599999785423279},{"id":"https://openalex.org/keywords/hypolipidemic-activity","display_name":"hypolipidemic activity","score":0.9850000143051147},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.8859999775886536},{"id":"https://openalex.org/keywords/polyphenols","display_name":"polyphenols","score":0.7049999833106995},{"id":"https://openalex.org/keywords/ayurveda","display_name":"Ayurveda","score":0.734000027179718}],"concepts":[{"id":"https://openalex.org/C2777781930","wikidata":"https://www.wikidata.org/wiki/Q1074417","display_name":"Mangiferin","level":2,"score":0.9886932969093323},{"id":"https://openalex.org/C2781429666","wikidata":"https://www.wikidata.org/wiki/Q161807","display_name":"Mangifera","level":2,"score":0.9325388669967651},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.7303910851478577},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.6087580323219299},{"id":"https://openalex.org/C70899900","wikidata":"https://www.wikidata.org/wiki/Q290439","display_name":"Polyphenol","level":3,"score":0.5862436294555664},{"id":"https://openalex.org/C2779703632","wikidata":"https://www.wikidata.org/wiki/Q581996","display_name":"Anti-inflammatory","level":2,"score":0.5004298686981201},{"id":"https://openalex.org/C188442228","wikidata":"https://www.wikidata.org/wiki/Q48286","display_name":"Pulp (tooth)","level":2,"score":0.49505725502967834},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40445461869239807},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4012189507484436},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.28597837686538696},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.19667187333106995},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18555516004562378},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.15744/2393-9060.5.303","doi":"https://doi.org/10.15744/2393-9060.5.303","is_oa":true,"landing_page_url":"https://doi.org/10.15744/2393-9060.5.303","pdf_url":"http://www.annexpublishers.com/articles/JNH/5303-A-Review-on-Antioxidant-Anti-Inflammatory-and-Gastroprotective-Abilities-of-Mango-Magnifera-Indica-Leaf-Extract-and-Mangiferin.pdf","source":{"id":"https://openalex.org/S4210176295","display_name":"Journal of Nutrition and Health Sciences","issn_l":"2393-9060","issn":["2393-9060"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Nutrition and Health Sciences","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.15744/2393-9060.5.303","doi":"https://doi.org/10.15744/2393-9060.5.303","is_oa":true,"landing_page_url":"https://doi.org/10.15744/2393-9060.5.303","pdf_url":"http://www.annexpublishers.com/articles/JNH/5303-A-Review-on-Antioxidant-Anti-Inflammatory-and-Gastroprotective-Abilities-of-Mango-Magnifera-Indica-Leaf-Extract-and-Mangiferin.pdf","source":{"id":"https://openalex.org/S4210176295","display_name":"Journal of Nutrition and Health Sciences","issn_l":"2393-9060","issn":["2393-9060"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Nutrition and Health Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2911736993.pdf","grobid_xml":"https://content.openalex.org/works/W2911736993.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W70931265","https://openalex.org/W186360487","https://openalex.org/W1966746756","https://openalex.org/W1969247731","https://openalex.org/W1971387061","https://openalex.org/W1971705630","https://openalex.org/W1976717028","https://openalex.org/W1991328746","https://openalex.org/W2005995075","https://openalex.org/W2023654730","https://openalex.org/W2025788843","https://openalex.org/W2035975952","https://openalex.org/W2051747835","https://openalex.org/W2052035877","https://openalex.org/W2056186650","https://openalex.org/W2058399743","https://openalex.org/W2062845180","https://openalex.org/W2087860045","https://openalex.org/W2090763605","https://openalex.org/W2134496342","https://openalex.org/W2163768586","https://openalex.org/W2169256832","https://openalex.org/W2170706201","https://openalex.org/W2183120901","https://openalex.org/W2268362641","https://openalex.org/W2311658947","https://openalex.org/W2335174081","https://openalex.org/W2344222630","https://openalex.org/W2405052429","https://openalex.org/W2461997959","https://openalex.org/W2550580911","https://openalex.org/W2559321460","https://openalex.org/W2588583503","https://openalex.org/W2594726289","https://openalex.org/W2598560533","https://openalex.org/W2610241935","https://openalex.org/W2611255994","https://openalex.org/W2729240317","https://openalex.org/W2741511748","https://openalex.org/W2747564881"],"related_works":["https://openalex.org/W2892037833","https://openalex.org/W7081963602","https://openalex.org/W3132015236","https://openalex.org/W2241527502","https://openalex.org/W2028921233","https://openalex.org/W3096136254","https://openalex.org/W4415103737","https://openalex.org/W2978900558","https://openalex.org/W1961074971","https://openalex.org/W4242780818"],"abstract_inverted_index":{"Mango":[0,50],"(Mangifera":[1],"indica":[2],"Linn.)":[3],"trees":[4,35],"have":[5,20,41],"been":[6,42],"cultivated":[7],"and":[8,12,19,38,47,52,78,84,101,108,122,131,138,170,174],"grown":[9],"in":[10,45,103],"Southern":[11],"Eastern":[13],"India":[14],"for":[15,128],"thousands":[16],"of":[17,33,65,75,93,97,134,152,167],"years":[18,30],"slowly":[21],"spread":[22],"all":[23],"over":[24,28],"the":[25,73,94,116,147,165,168],"world.":[26],"For":[27],"4,000":[29],"various":[31],"parts":[32],"mango":[34,98,135],"including":[36,60,72],"leaf":[37,99,136],"fruit":[39],"pulp":[40,51],"extensively":[43],"used":[44],"Ayurvedic":[46],"Unani":[48],"medicines.":[49],"leaves":[53],"contain":[54],"diverse":[55,69],"health":[56,77,110,132],"promoting":[57,104],"chemical":[58],"constituents":[59],"mangiferin,":[61],"a":[62,90],"natural":[63],"polyphenol":[64],"C-glycosylxanthone":[66],"structure,":[67],"with":[68],"pharmacological/physiological":[70],"activities":[71],"promotion":[74],"gut":[76,109],"regularity,":[79],"as":[80,82,125,127,154,156],"well":[81,126,155],"antioxidant":[83],"anti-inflammatory":[85,161],"benefits.":[86,111],"This":[87],"review":[88],"provides":[89],"detailed":[91],"discussion":[92],"nutritional":[95],"benefits":[96,133],"extract":[100],"mangiferin":[102,139,153],"anti-inflammatory,":[105],"antioxidant,":[106],"gastrointestinal":[107],"In":[112],"addition,":[113],"information":[114],"regarding":[115],"tissue":[117],"protective,":[118],"immunomodulatory,":[119],"antidiabetic,":[120],"anti-hyperlipidemic":[121],"anti-cancer":[123],"properties,":[124],"disease":[129],"management":[130],"extracts":[137],"will":[140,179],"be":[141,180],"reviewed.":[142],"Furthermore,":[143],"mechanistic":[144],"studies":[145],"involving":[146],"free":[148],"radical":[149],"scavenging":[150],"ability":[151,158],"its":[157],"to":[159],"exert":[160],"activity":[162],"by":[163],"inhibiting":[164],"expression":[166],"TNF-\u03b1":[169],"related":[171],"signaling":[172],"mechanisms":[173],"inducible":[175],"nitric":[176],"oxide":[177],"synthase":[178],"considered.":[181]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-02-21T00:00:00"}
