{"id":"https://openalex.org/W2911684398","doi":"https://doi.org/10.2147/jpr.s191848","title":"Could epigenetics help explain racial disparities in chronic pain?","display_name":"Could epigenetics help explain racial disparities in chronic pain?","publication_year":2019,"publication_date":"2019-02-01","ids":{"openalex":"https://openalex.org/W2911684398","doi":"https://doi.org/10.2147/jpr.s191848","mag":"2911684398","pmid":"https://pubmed.ncbi.nlm.nih.gov/30863142"},"language":"en","primary_location":{"id":"doi:10.2147/jpr.s191848","doi":"https://doi.org/10.2147/jpr.s191848","is_oa":true,"landing_page_url":"https://doi.org/10.2147/jpr.s191848","pdf_url":"https://www.dovepress.com/getfile.php?fileID=48105","source":{"id":"https://openalex.org/S130650480","display_name":"Journal of Pain Research","issn_l":"1178-7090","issn":["1178-7090"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pain Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/getfile.php?fileID=48105","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077475864","display_name":"Edwin N. Aroke","orcid":"https://orcid.org/0000-0002-8355-0870","observed_orcids":["https://orcid.org/0000-0002-8355-0870"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edwin N Aroke","raw_affiliation_strings":["School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA, earoke@uab.edu","School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA"],"raw_orcid":"https://orcid.org/0000-0002-8355-0870","affiliations":[{"raw_affiliation_string":"School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA, earoke@uab.edu","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058203848","display_name":"Paule V. Joseph","orcid":"https://orcid.org/0000-0002-1198-9622","observed_orcids":["https://orcid.org/0000-0002-1198-9622"]},"institutions":[{"id":"https://openalex.org/I1299022934","display_name":"United States Department of Health and Human Services","ror":"https://ror.org/033jnv181","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110704","display_name":"National Institute of Nursing Research","ror":"https://ror.org/01y3zfr79","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paule V Joseph","raw_affiliation_strings":["Sensory Science and Metabolism Unit (SenSMet), Division of Intramural Research, National Institute of Nursing Research, National Institute of Health, DHHS, Bethesda, MD, USA"],"raw_orcid":"https://orcid.org/0000-0002-1198-9622","affiliations":[{"raw_affiliation_string":"Sensory Science and Metabolism Unit (SenSMet), Division of Intramural Research, National Institute of Nursing Research, National Institute of Health, DHHS, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110704"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069220896","display_name":"Abhrarup Roy","orcid":"https://orcid.org/0000-0003-1590-4531","observed_orcids":["https://orcid.org/0000-0003-1590-4531"]},"institutions":[{"id":"https://openalex.org/I1299022934","display_name":"United States Department of Health and Human Services","ror":"https://ror.org/033jnv181","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110704","display_name":"National Institute of Nursing Research","ror":"https://ror.org/01y3zfr79","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110704"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abhrarup Roy","raw_affiliation_strings":["Sensory Science and Metabolism Unit (SenSMet), Division of Intramural Research, National Institute of Nursing Research, National Institute of Health, DHHS, Bethesda, MD, USA"],"raw_orcid":"https://orcid.org/0000-0003-1590-4531","affiliations":[{"raw_affiliation_string":"Sensory Science and Metabolism Unit (SenSMet), Division of Intramural Research, National Institute of Nursing Research, National Institute of Health, DHHS, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110704"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091493652","display_name":"Demario S. Overstreet","orcid":"https://orcid.org/0000-0002-8485-4454","observed_orcids":["https://orcid.org/0000-0002-8485-4454"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Demario S Overstreet","raw_affiliation_strings":["Department of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001695890","display_name":"Trygve O. Tollefsbol","orcid":"https://orcid.org/0000-0002-0284-1511","observed_orcids":["https://orcid.org/0000-0002-0284-1511"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Trygve O Tollefsbol","raw_affiliation_strings":["Department of Biology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033711664","display_name":"David E. Vance","orcid":"https://orcid.org/0000-0002-0498-6263","observed_orcids":["https://orcid.org/0000-0002-0498-6263"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David E Vance","raw_affiliation_strings":["School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA, earoke@uab.edu","School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA"],"raw_orcid":"https://orcid.org/0000-0002-0498-6263","affiliations":[{"raw_affiliation_string":"School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA, earoke@uab.edu","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082788779","display_name":"Burel R. Goodin","orcid":"https://orcid.org/0000-0002-8159-1310","observed_orcids":["https://orcid.org/0000-0002-8159-1310"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Burel R Goodin","raw_affiliation_strings":["Department of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA"],"raw_orcid":"https://orcid.org/0000-0002-8159-1310","affiliations":[{"raw_affiliation_string":"Department of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA","institution_ids":["https://openalex.org/I32389192"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":3.2939,"has_fulltext":true,"cited_by_count":84,"citation_normalized_percentile":{"value":0.93609478,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"Volume 12","issue":null,"first_page":"701","last_page":"710"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.8804000020027161,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.8804000020027161,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12749","display_name":"Race, Genetics, and Society","score":0.018200000748038292,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-pain","display_name":"chronic pain","score":0.9539999961853027},{"id":"https://openalex.org/keywords/racial-disparities","display_name":"racial disparities","score":0.7110000252723694},{"id":"https://openalex.org/keywords/epigenetics","display_name":"epigenetics","score":0.9700000286102295},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.9739999771118164},{"id":"https://openalex.org/keywords/african-americans","display_name":"African Americans","score":0.9760000109672546},{"id":"https://openalex.org/keywords/racial-discrimination","display_name":"racial discrimination","score":0.6010000109672546},{"id":"https://openalex.org/keywords/childhood-adversity","display_name":"childhood adversity","score":0.7540000081062317},{"id":"https://openalex.org/keywords/socioeconomic-status","display_name":"socioeconomic status","score":0.8360000252723694},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.9520000219345093},{"id":"https://openalex.org/keywords/chronic-stress","display_name":"chronic stress","score":0.8429999947547913},{"id":"https://openalex.org/keywords/glucocorticoid-receptor","display_name":"glucocorticoid receptor","score":0.9020000100135803},{"id":"https://openalex.org/keywords/nr3c1","display_name":"NR3C1","score":0.9559999704360962},{"id":"https://openalex.org/keywords/epigenomics","display_name":"epigenomics","score":0.7200000286102295}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9667084217071533},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.6521884202957153},{"id":"https://openalex.org/C2781118164","wikidata":"https://www.wikidata.org/wiki/Q1088113","display_name":"Chronic pain","level":2,"score":0.5040630102157593},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38080865144729614},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22418594360351562},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.19251665472984314},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13847234845161438},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.2147/jpr.s191848","doi":"https://doi.org/10.2147/jpr.s191848","is_oa":true,"landing_page_url":"https://doi.org/10.2147/jpr.s191848","pdf_url":"https://www.dovepress.com/getfile.php?fileID=48105","source":{"id":"https://openalex.org/S130650480","display_name":"Journal of Pain Research","issn_l":"1178-7090","issn":["1178-7090"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pain Research","raw_type":"journal-article"},{"id":"pmid:30863142","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30863142","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pain research","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5397078","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6388771","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6388771","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6388771","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Pain Res","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:5bd8526e2dbc4bf2b1bd9d8158cf6dad","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/5bd8526e2dbc4bf2b1bd9d8158cf6dad","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Pain Research, Vol Volume 12, Pp 701-710 (2019)","raw_type":"article"},{"id":"pmh:oai:dovepress.com/44145","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/could-epigenetics-help-explain-racial-disparities-in-chronic-pain-peer-reviewed-article-JPR","pdf_url":null,"source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Review"}],"best_oa_location":{"id":"doi:10.2147/jpr.s191848","doi":"https://doi.org/10.2147/jpr.s191848","is_oa":true,"landing_page_url":"https://doi.org/10.2147/jpr.s191848","pdf_url":"https://www.dovepress.com/getfile.php?fileID=48105","source":{"id":"https://openalex.org/S130650480","display_name":"Journal of Pain Research","issn_l":"1178-7090","issn":["1178-7090"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pain Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/10","score":0.7390999794006348,"display_name":"Reduced inequalities"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/10","score":0.6399999856948853,"display_name":"Reduced inequalities"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1471628300","display_name":null,"funder_award_id":"T32HS013852","funder_id":"https://openalex.org/F4320337353","funder_display_name":"National Institute of Nursing Research"},{"id":"https://openalex.org/G2481925725","display_name":null,"funder_award_id":"1ZIANR000035-01","funder_id":"https://openalex.org/F4320337353","funder_display_name":"National Institute of Nursing Research"},{"id":"https://openalex.org/G5709402805","display_name":"UAB HEALTH SERVICES & OUTCOMES RESEARCH TRAINING PROGRAM","funder_award_id":"T32HS013852","funder_id":"https://openalex.org/F4320332177","funder_display_name":"Agency for Healthcare Research and Quality"},{"id":"https://openalex.org/G5836250296","display_name":null,"funder_award_id":"T32HS013852","funder_id":"https://openalex.org/F4320312852","funder_display_name":"University of Alabama"},{"id":"https://openalex.org/G617835510","display_name":null,"funder_award_id":"R01 MD010441","funder_id":"https://openalex.org/F4320337534","funder_display_name":"National Institute on Minority Health and Health Disparities"},{"id":"https://openalex.org/G7856330779","display_name":"Sensory Science and Metabolism; Molecular and Neuronal Mechanisms","funder_award_id":"1zianr000035-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000079594","display_name":null,"funder_award_id":"R01MD010441","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000266039","display_name":null,"funder_award_id":"ZIA NR000035","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320310431","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205"},{"id":"https://openalex.org/F4320312852","display_name":"University of Alabama","ror":"https://ror.org/03xrrjk67"},{"id":"https://openalex.org/F4320312873","display_name":"American Association of Nurse Anesthetists","ror":"https://ror.org/03rpes181"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332177","display_name":"Agency for Healthcare Research and Quality","ror":"https://ror.org/03jmfdf59"},{"id":"https://openalex.org/F4320337353","display_name":"National Institute of Nursing Research","ror":"https://ror.org/01y3zfr79"},{"id":"https://openalex.org/F4320337534","display_name":"National Institute on Minority Health and Health Disparities","ror":"https://ror.org/0493hgw16"},{"id":"https://openalex.org/F4320338421","display_name":"NHLBI Division of Intramural Research","ror":"https://ror.org/023ny1p48"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2911684398.pdf","grobid_xml":"https://content.openalex.org/works/W2911684398.grobid-xml"},"referenced_works_count":81,"referenced_works":["https://openalex.org/W611051872","https://openalex.org/W854901204","https://openalex.org/W1627232924","https://openalex.org/W1680632626","https://openalex.org/W1851806939","https://openalex.org/W1921612365","https://openalex.org/W1930346527","https://openalex.org/W1944231772","https://openalex.org/W1981459575","https://openalex.org/W1989924524","https://openalex.org/W1991925547","https://openalex.org/W1998137132","https://openalex.org/W2000492372","https://openalex.org/W2004052823","https://openalex.org/W2013245174","https://openalex.org/W2013978233","https://openalex.org/W2023734508","https://openalex.org/W2024277158","https://openalex.org/W2024387581","https://openalex.org/W2026359019","https://openalex.org/W2026453995","https://openalex.org/W2035899017","https://openalex.org/W2040661643","https://openalex.org/W2049473372","https://openalex.org/W2058549094","https://openalex.org/W2059392494","https://openalex.org/W2068301455","https://openalex.org/W2074029111","https://openalex.org/W2076507733","https://openalex.org/W2090541572","https://openalex.org/W2093414972","https://openalex.org/W2093817250","https://openalex.org/W2104552725","https://openalex.org/W2112851246","https://openalex.org/W2116365496","https://openalex.org/W2116839388","https://openalex.org/W2120215564","https://openalex.org/W2122743728","https://openalex.org/W2124986716","https://openalex.org/W2128272446","https://openalex.org/W2130096402","https://openalex.org/W2133338739","https://openalex.org/W2135480836","https://openalex.org/W2138237282","https://openalex.org/W2139954995","https://openalex.org/W2143858605","https://openalex.org/W2145452721","https://openalex.org/W2152656267","https://openalex.org/W2153316951","https://openalex.org/W2158037744","https://openalex.org/W2167015768","https://openalex.org/W2170760271","https://openalex.org/W2213350231","https://openalex.org/W2217604376","https://openalex.org/W2238316952","https://openalex.org/W2259875174","https://openalex.org/W2263626698","https://openalex.org/W2272404123","https://openalex.org/W2292840995","https://openalex.org/W2318723339","https://openalex.org/W2325781243","https://openalex.org/W2405768639","https://openalex.org/W2410110573","https://openalex.org/W2517358371","https://openalex.org/W2593056494","https://openalex.org/W2597871760","https://openalex.org/W2631752818","https://openalex.org/W2740079295","https://openalex.org/W2741522336","https://openalex.org/W2754346516","https://openalex.org/W2785731967","https://openalex.org/W2792805148","https://openalex.org/W2793659156","https://openalex.org/W2803734949","https://openalex.org/W2807228374","https://openalex.org/W2807831325","https://openalex.org/W2809714974","https://openalex.org/W2968674390","https://openalex.org/W4235272869","https://openalex.org/W4252222606","https://openalex.org/W6604370743"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W2586801360","https://openalex.org/W3108674512","https://openalex.org/W1506200166","https://openalex.org/W1489783725"],"abstract_inverted_index":{"Abstract:":[0],"African":[1,62,227],"Americans":[2,63],"disproportionately":[3],"suffer":[4],"more":[5,65,220],"severe":[6,221],"and":[7,26,39,50,101,174,222],"debilitating":[8],"morbidity":[9],"from":[10,21],"chronic":[11,48,51,83,137,145,175,189,206,224,230],"pain":[12,146,207,225],"than":[13],"do":[14],"non-Hispanic":[15],"Whites.":[16],"These":[17],"differences":[18,81,135],"may":[19,74,196],"arise":[20],"differential":[22,129],"exposure":[23,131],"to":[24,67,219],"psychosocial":[25],"environmental":[27,91,130],"factors":[28,92],"such":[29,60,93],"as":[30,54,94,124],"adverse":[31],"childhood":[32,95,169],"experiences,":[33],"racial":[34,80,97,134,233],"discrimination,":[35,98],"low":[36,171],"socioeconomic":[37,172],"status,":[38,173],"depression,":[40,168],"all":[41],"of":[42,119,141,181,205,215],"which":[43,73,90,128,163],"have":[44,185],"been":[45,165,186],"associated":[46,166,187],"with":[47,167,188,211],"stress":[49,190,239],"pain.":[52,84,138,176],"Race,":[53],"a":[55,116,125,212],"social":[56],"construct,":[57],"makes":[58],"it":[59],"that":[61,78],"are":[64],"likely":[66],"experience":[68],"different":[69,209],"early":[70],"life":[71],"conditions,":[72],"induce":[75],"epigenetic":[76,142,203,216],"changes":[77,143,195],"sustain":[79],"in":[82,136,144,154,201,208,226],"Epigenetics":[85],"is":[86,152],"one":[87],"mechanism":[88,126],"by":[89,127],"stress,":[96,170],"economic":[99],"hardship,":[100],"depression":[102],"can":[103],"affect":[104],"gene":[105],"expression":[106],"without":[107],"altering":[108],"the":[109,120,155,202],"underlying":[110],"genetic":[111],"sequence.":[112],"This":[113],"article":[114],"provides":[115],"narrative":[117],"review":[118],"literature":[121],"on":[122],"epigenetics":[123],"could":[132],"explain":[133],"Most":[139],"studies":[140],"examine":[147],"DNA":[148,150,178,193,237],"methylation.":[149],"methylation":[151,179,194],"altered":[153],"glucocorticoid":[156],"(stress":[157],"response)":[158],"receptor":[159],"gene,":[160],"NR3C1":[161],",":[162],"has":[164],"Similarly,":[177],"patterns":[180],"immune":[182],"cytokine":[183],"genes":[184],"states.":[191],"Thus,":[192],"play":[197],"an":[198],"essential":[199],"role":[200],"modulation":[204],"races":[210],"higher":[213],"incidence":[214],"alterations":[217],"contributing":[218],"disabling":[223],"Americans.":[228],"Keywords:":[229],"pain,":[231],"epigenetics,":[232],"health":[234],"disparities,":[235],"epigenomics,":[236],"methylation,":[238]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2019-02-21T00:00:00"}
