{"id":"https://openalex.org/W2911284024","doi":"https://doi.org/10.1038/s41598-018-38240-9","title":"Computational and spectroscopic analysis of interaction between food colorant citrus red 2 and human serum albumin","display_name":"Computational and spectroscopic analysis of interaction between food colorant citrus red 2 and human serum albumin","publication_year":2019,"publication_date":"2019-02-07","ids":{"openalex":"https://openalex.org/W2911284024","doi":"https://doi.org/10.1038/s41598-018-38240-9","mag":"2911284024","pmid":"https://pubmed.ncbi.nlm.nih.gov/30733529","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6367341"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-018-38240-9","doi":"https://doi.org/10.1038/s41598-018-38240-9","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-38240-9","pdf_url":"https://www.nature.com/articles/s41598-018-38240-9.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-018-38240-9.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023518132","display_name":"Di Wu","orcid":"https://orcid.org/0000-0003-4364-5098","observed_orcids":["https://orcid.org/0000-0003-4364-5098"]},"institutions":[{"id":"https://openalex.org/I4210125143","display_name":"Chengdu University","ror":"https://ror.org/034z67559","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210125143"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Di Wu","raw_affiliation_strings":["Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China. diwulab@163.com","Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China. diwulab@163.com","institution_ids":["https://openalex.org/I4210125143"]},{"raw_affiliation_string":"Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China","institution_ids":["https://openalex.org/I4210125143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064952241","display_name":"Jinqiu Wang","orcid":"https://orcid.org/0000-0003-1736-3652","observed_orcids":["https://orcid.org/0000-0003-1736-3652"]},"institutions":[{"id":"https://openalex.org/I4210125143","display_name":"Chengdu University","ror":"https://ror.org/034z67559","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210125143"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinqiu Wang","raw_affiliation_strings":["Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China","institution_ids":["https://openalex.org/I4210125143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102772315","display_name":"Dayu Liu","orcid":"https://orcid.org/0009-0001-3693-1507","observed_orcids":["https://orcid.org/0009-0001-3693-1507"]},"institutions":[{"id":"https://openalex.org/I4210125143","display_name":"Chengdu University","ror":"https://ror.org/034z67559","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210125143"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dayu Liu","raw_affiliation_strings":["Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China","institution_ids":["https://openalex.org/I4210125143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100343696","display_name":"Yin Zhang","orcid":"https://orcid.org/0009-0002-8307-0938","observed_orcids":["https://orcid.org/0009-0002-8307-0938","https://orcid.org/0000-0001-5847-4725"]},"institutions":[{"id":"https://openalex.org/I4210125143","display_name":"Chengdu University","ror":"https://ror.org/034z67559","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210125143"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yin Zhang","raw_affiliation_strings":["Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China","institution_ids":["https://openalex.org/I4210125143"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090722197","display_name":"Xia Hu","orcid":"https://orcid.org/0000-0003-3991-3184","observed_orcids":["https://orcid.org/0000-0003-3991-3184","https://orcid.org/0009-0004-4541-9902"]},"institutions":[{"id":"https://openalex.org/I4210125143","display_name":"Chengdu University","ror":"https://ror.org/034z67559","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210125143"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xia Hu","raw_affiliation_strings":["Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Meat Processing of Sichuan, College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610106, China","institution_ids":["https://openalex.org/I4210125143"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5023518132"],"corresponding_institution_ids":["https://openalex.org/I4210125143"],"apc_list":{"value":1790,"currency":"USD","value_usd":1790},"apc_paid":{"value":1790,"currency":"USD","value_usd":1790},"fwci":1.0749,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.74121878,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"9","issue":"1","first_page":"1615","last_page":"1615"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11908","display_name":"Protein Interaction Studies and Fluorescence Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11908","display_name":"Protein Interaction Studies and Fluorescence Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13325","display_name":"Dye analysis and toxicity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11129","display_name":"Photochemistry and Electron Transfer Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/food-colorants","display_name":"food colorants","score":0.7149999737739563},{"id":"https://openalex.org/keywords/human-serum-albumin","display_name":"human serum albumin","score":1.0},{"id":"https://openalex.org/keywords/protein-ligand-binding","display_name":"protein-ligand binding","score":0.8809999823570251},{"id":"https://openalex.org/keywords/static-quenching","display_name":"static quenching","score":0.8059999942779541},{"id":"https://openalex.org/keywords/binding-constant","display_name":"binding constant","score":0.7419999837875366},{"id":"https://openalex.org/keywords/electrostatic-interactions","display_name":"electrostatic interactions","score":0.8960000276565552},{"id":"https://openalex.org/keywords/fluorescence-quenching","display_name":"fluorescence quenching","score":0.7250000238418579},{"id":"https://openalex.org/keywords/circular-dichroism","display_name":"circular dichroism","score":0.8339999914169312},{"id":"https://openalex.org/keywords/helical-content","display_name":"alpha-helix content","score":0.7350000143051147},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.7089999914169312},{"id":"https://openalex.org/keywords/molecular-dynamics-simulation","display_name":"molecular dynamics simulation","score":0.7400000095367432},{"id":"https://openalex.org/keywords/bioaccumulation","display_name":"bioaccumulation","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C133571119","wikidata":"https://www.wikidata.org/wiki/Q899102","display_name":"Circular dichroism","level":2,"score":0.8237159252166748},{"id":"https://openalex.org/C2778597219","wikidata":"https://www.wikidata.org/wiki/Q11721976","display_name":"Human serum albumin","level":2,"score":0.79518723487854},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.647010326385498},{"id":"https://openalex.org/C121745418","wikidata":"https://www.wikidata.org/wiki/Q585536","display_name":"Quenching (fluorescence)","level":3,"score":0.5992602705955505},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.5961884260177612},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.5631217956542969},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5108997225761414},{"id":"https://openalex.org/C32786932","wikidata":"https://www.wikidata.org/wiki/Q4914013","display_name":"Binding constant","level":3,"score":0.4959758222103119},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.42624953389167786},{"id":"https://openalex.org/C59593255","wikidata":"https://www.wikidata.org/wiki/Q901663","display_name":"Molecular dynamics","level":2,"score":0.41814643144607544},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.27391815185546875},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.2588781714439392},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24186745285987854},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0922030508518219},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000075462","descriptor_name":"Serum Albumin, Human","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000075462","descriptor_name":"Serum Albumin, Human","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001391","descriptor_name":"Azo Compounds","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005505","descriptor_name":"Food Coloring Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013057","descriptor_name":"Spectrum Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41598-018-38240-9","doi":"https://doi.org/10.1038/s41598-018-38240-9","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-38240-9","pdf_url":"https://www.nature.com/articles/s41598-018-38240-9.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5358533","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6367341","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6367341","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6367341","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmid:30733529","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30733529","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:1fdce260fc2849efb51a0f949caad2fa","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/1fdce260fc2849efb51a0f949caad2fa","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41598-018-38240-9","doi":"https://doi.org/10.1038/s41598-018-38240-9","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-38240-9","pdf_url":"https://www.nature.com/articles/s41598-018-38240-9.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"score":0.5199999809265137,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7623316736","display_name":null,"funder_award_id":"21808020","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2911284024.pdf","grobid_xml":"https://content.openalex.org/works/W2911284024.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W299894722","https://openalex.org/W846884586","https://openalex.org/W1176559875","https://openalex.org/W1548941984","https://openalex.org/W1595151435","https://openalex.org/W1992098105","https://openalex.org/W2013848575","https://openalex.org/W2018182705","https://openalex.org/W2018831103","https://openalex.org/W2026447666","https://openalex.org/W2026789919","https://openalex.org/W2036393306","https://openalex.org/W2039528655","https://openalex.org/W2062824768","https://openalex.org/W2065366424","https://openalex.org/W2075705506","https://openalex.org/W2076724751","https://openalex.org/W2090427843","https://openalex.org/W2100390617","https://openalex.org/W2122775680","https://openalex.org/W2123880728","https://openalex.org/W2126588926","https://openalex.org/W2149753318","https://openalex.org/W2154792548","https://openalex.org/W2157020830","https://openalex.org/W2281410876","https://openalex.org/W2291664493","https://openalex.org/W2324955203","https://openalex.org/W2330451522","https://openalex.org/W2346529285","https://openalex.org/W2474328750","https://openalex.org/W2486200026","https://openalex.org/W2520798170","https://openalex.org/W2591099301","https://openalex.org/W2617041541","https://openalex.org/W2623434963","https://openalex.org/W2742322428","https://openalex.org/W2743996242","https://openalex.org/W2753895568","https://openalex.org/W2765285487","https://openalex.org/W2779691110","https://openalex.org/W2783392996","https://openalex.org/W2793002236","https://openalex.org/W2894079764","https://openalex.org/W2907897161","https://openalex.org/W4211130281","https://openalex.org/W4231721248"],"related_works":["https://openalex.org/W2026789919","https://openalex.org/W4247359523","https://openalex.org/W4205843674","https://openalex.org/W2079901180","https://openalex.org/W4380606444","https://openalex.org/W2386715636","https://openalex.org/W4311715207","https://openalex.org/W1979084943","https://openalex.org/W2060469583","https://openalex.org/W2332314294"],"abstract_inverted_index":{"Abstract":[0],"The":[1,104,137],"main":[2],"aim":[3],"of":[4,83,91,96,132],"this":[5],"work":[6],"was":[7,110],"to":[8,44,144],"gain":[9],"insight":[10],"into":[11],"the":[12,30,48,73,89,101,123,126,147,155],"binding":[13,61,81,90,105],"properties":[14],"between":[15,50],"a":[16,59],"food":[17,148],"colorant,":[18],"citrus":[19],"red":[20],"2":[21],"(CR),":[22],"and":[23,39,46,52,55,68,109,118,129,139,151],"human":[24,156],"serum":[25],"albumin":[26],"(HSA),":[27],"which":[28,98],"is":[29],"predominant":[31],"protein":[32],"in":[33,125,154],"blood":[34],"plasma.":[35],"Here,":[36],"computer":[37],"simulations":[38],"multiple":[40],"spectroscopies":[41],"were":[42],"applied":[43],"predict":[45],"characterize":[47],"interaction":[49],"CR":[51,92],"HSA.":[53],"Docking":[54],"molecular":[56],"dynamics":[57],"presented":[58],"stable":[60],"configuration":[62],"with":[63,80,100],"low":[64],"fluctuations.":[65],"Fluorescence":[66],"spectroscopy":[67],"lifetime":[69],"results":[70],"suggested":[71],"that":[72],"CR\u2013HSA":[74],"combination":[75],"undergoes":[76],"static":[77],"quenching":[78],"mechanism":[79],"constant":[82],"105":[84],"L/mol.":[85],"Displacement":[86],"analysis":[87],"showed":[88],"at":[93],"site":[94],"I":[95],"HSA,":[97],"agrees":[99],"docking":[102],"results.":[103],"process":[106],"occured":[107],"spontaneously":[108],"mainly":[111],"driven":[112],"by":[113,135],"electrostatic":[114],"interactions.":[115],"Synchronous":[116],"fluorescence":[117],"circular":[119],"dichroism":[120],"measurements":[121],"demonstrate":[122],"changes":[124],"microenvironment":[127],"residues":[128],"\u03b1-helix":[130],"contents":[131],"HSA":[133],"induced":[134],"CR.":[136],"computational":[138],"experimental":[140],"techniques":[141],"are":[142],"complementary":[143],"clearly":[145],"understand":[146],"colorant":[149],"transportation":[150],"bioaccumulative":[152],"toxicity":[153],"body.":[157]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-02-21T00:00:00"}