{"id":"https://openalex.org/W2910262575","doi":"https://doi.org/10.1177/1179069518821917","title":"Electrophysiology of Syncytial Smooth Muscle","display_name":"Electrophysiology of Syncytial Smooth Muscle","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2910262575","doi":"https://doi.org/10.1177/1179069518821917","mag":"2910262575","pmid":"https://pubmed.ncbi.nlm.nih.gov/30733629","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6343439"},"language":"en","primary_location":{"id":"doi:10.1177/1179069518821917","doi":"https://doi.org/10.1177/1179069518821917","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1179069518821917","pdf_url":null,"source":{"id":"https://openalex.org/S2736527329","display_name":"Journal of Experimental Neuroscience","issn_l":"1179-0695","issn":["1179-0695"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-70"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Neuroscience","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1177/1179069518821917","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058762205","display_name":"Rohit Manchanda","orcid":"https://orcid.org/0000-0001-7383-3482","observed_orcids":["https://orcid.org/0000-0001-7383-3482"]},"institutions":[{"id":"https://openalex.org/I162827531","display_name":"Indian Institute of Technology Bombay","ror":"https://ror.org/02qyf5152","country_code":"IN","type":"education","lineage":["https://openalex.org/I162827531"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Rohit Manchanda","raw_affiliation_strings":["Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, India"],"raw_orcid":"https://orcid.org/0000-0001-7383-3482","affiliations":[{"raw_affiliation_string":"Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, India","institution_ids":["https://openalex.org/I162827531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066574247","display_name":"Shailesh Appukuttan","orcid":"https://orcid.org/0000-0002-0148-8023","observed_orcids":["https://orcid.org/0000-0002-0148-8023"]},"institutions":[{"id":"https://openalex.org/I162827531","display_name":"Indian Institute of Technology Bombay","ror":"https://ror.org/02qyf5152","country_code":"IN","type":"education","lineage":["https://openalex.org/I162827531"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Shailesh Appukuttan","raw_affiliation_strings":["Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, India","institution_ids":["https://openalex.org/I162827531"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072394250","display_name":"Mithun Padmakumar","orcid":"https://orcid.org/0000-0002-5305-4542","observed_orcids":["https://orcid.org/0000-0002-5305-4542"]},"institutions":[{"id":"https://openalex.org/I162827531","display_name":"Indian Institute of Technology Bombay","ror":"https://ror.org/02qyf5152","country_code":"IN","type":"education","lineage":["https://openalex.org/I162827531"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mithun Padmakumar","raw_affiliation_strings":["Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, India"],"raw_orcid":"https://orcid.org/0000-0002-5305-4542","affiliations":[{"raw_affiliation_string":"Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, India","institution_ids":["https://openalex.org/I162827531"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5058762205"],"corresponding_institution_ids":["https://openalex.org/I162827531"],"apc_list":{"value":1500,"currency":"USD","value_usd":1500},"apc_paid":{"value":1500,"currency":"USD","value_usd":1500},"fwci":0.1565,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.11608608,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"13","issue":null,"first_page":"1179069518821917","last_page":"1179069518821917"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.8413000106811523,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.8413000106811523,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.05920000001788139,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.014800000004470348,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/junction-potentials","display_name":"junction potentials","score":0.9509999752044678},{"id":"https://openalex.org/keywords/action-potential","display_name":"action potential","score":0.9589999914169312},{"id":"https://openalex.org/keywords/smooth-muscle-electrophysiology","display_name":"smooth muscle electrophysiology","score":0.7850000262260437},{"id":"https://openalex.org/keywords/neurotransmission","display_name":"neurotransmission","score":0.6259999871253967},{"id":"https://openalex.org/keywords/excitation-spread","display_name":"excitation spread","score":0.6850000023841858},{"id":"https://openalex.org/keywords/computational-model","display_name":"computational model","score":0.7480000257492065},{"id":"https://openalex.org/keywords/vas-deferens","display_name":"vas deferens","score":0.9169999957084656},{"id":"https://openalex.org/keywords/bladder","display_name":"urinary bladder","score":0.9300000071525574},{"id":"https://openalex.org/keywords/smooth-muscle-contractility","display_name":"smooth muscle contractility","score":0.5230000019073486}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6971280574798584},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.5863706469535828},{"id":"https://openalex.org/C2992686903","wikidata":"https://www.wikidata.org/wiki/Q208453","display_name":"Smooth muscle","level":2,"score":0.4742271602153778},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.423492968082428},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3991847634315491},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35681188106536865},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1177/1179069518821917","doi":"https://doi.org/10.1177/1179069518821917","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1179069518821917","pdf_url":null,"source":{"id":"https://openalex.org/S2736527329","display_name":"Journal of Experimental Neuroscience","issn_l":"1179-0695","issn":["1179-0695"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-70"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Neuroscience","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5354822","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6343439","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6343439","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6343439","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Neurosci","raw_type":"Text"},{"id":"pmid:30733629","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30733629","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of experimental neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:fb89dceaaa354378930c25132c5f7e28","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/fb89dceaaa354378930c25132c5f7e28","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Experimental Neuroscience, Vol 13 (2019)","raw_type":"article"},{"id":"pmh:oai:dsapce.library.iitb.ac.in:100/27321","doi":null,"is_oa":false,"landing_page_url":"http://dspace.library.iitb.ac.in/xmlui/handle/100/27321","pdf_url":null,"source":{"id":"https://openalex.org/S4306400899","display_name":"DSpace (IIT Bombay)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I162827531","host_organization_name":"Indian Institute of Technology Bombay","host_organization_lineage":["https://openalex.org/I162827531"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1177/1179069518821917","doi":"https://doi.org/10.1177/1179069518821917","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1179069518821917","pdf_url":null,"source":{"id":"https://openalex.org/S2736527329","display_name":"Journal of Experimental Neuroscience","issn_l":"1179-0695","issn":["1179-0695"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-70"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2739494753","display_name":null,"funder_award_id":"BT/PR12973/MED/122/ 47/2016","funder_id":"https://openalex.org/F4320320717","funder_display_name":"Department of Biotechnology, Ministry of Science and Technology, India"}],"funders":[{"id":"https://openalex.org/F4320320717","display_name":"Department of Biotechnology, Ministry of Science and Technology, India","ror":"https://ror.org/03tjsyq23"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":89,"referenced_works":["https://openalex.org/W5781756","https://openalex.org/W45904578","https://openalex.org/W1271656581","https://openalex.org/W1589154364","https://openalex.org/W1602123272","https://openalex.org/W1964585675","https://openalex.org/W1965363502","https://openalex.org/W1970761653","https://openalex.org/W1978415749","https://openalex.org/W1981841025","https://openalex.org/W1982618313","https://openalex.org/W1986498401","https://openalex.org/W1987823091","https://openalex.org/W1989865006","https://openalex.org/W1992993897","https://openalex.org/W1993476523","https://openalex.org/W1994088839","https://openalex.org/W1994937235","https://openalex.org/W1996918100","https://openalex.org/W2006012007","https://openalex.org/W2008160921","https://openalex.org/W2008697836","https://openalex.org/W2011100342","https://openalex.org/W2014101284","https://openalex.org/W2017353450","https://openalex.org/W2018388251","https://openalex.org/W2019998885","https://openalex.org/W2020561430","https://openalex.org/W2022182637","https://openalex.org/W2023747001","https://openalex.org/W2026277535","https://openalex.org/W2029972291","https://openalex.org/W2030800423","https://openalex.org/W2030892577","https://openalex.org/W2032928955","https://openalex.org/W2036904529","https://openalex.org/W2038357906","https://openalex.org/W2039867832","https://openalex.org/W2040009351","https://openalex.org/W2044369904","https://openalex.org/W2044846185","https://openalex.org/W2056239903","https://openalex.org/W2057856846","https://openalex.org/W2058275819","https://openalex.org/W2058564273","https://openalex.org/W2064145357","https://openalex.org/W2067428320","https://openalex.org/W2068032958","https://openalex.org/W2070716170","https://openalex.org/W2072969415","https://openalex.org/W2077162385","https://openalex.org/W2077925055","https://openalex.org/W2078369836","https://openalex.org/W2081298722","https://openalex.org/W2081556250","https://openalex.org/W2081922464","https://openalex.org/W2089607481","https://openalex.org/W2089881797","https://openalex.org/W2092335186","https://openalex.org/W2094213773","https://openalex.org/W2094235915","https://openalex.org/W2095497840","https://openalex.org/W2095937483","https://openalex.org/W2104626090","https://openalex.org/W2105981664","https://openalex.org/W2106081526","https://openalex.org/W2110140058","https://openalex.org/W2117059432","https://openalex.org/W2117358584","https://openalex.org/W2134117505","https://openalex.org/W2134696085","https://openalex.org/W2135322596","https://openalex.org/W2138195401","https://openalex.org/W2142939273","https://openalex.org/W2150987908","https://openalex.org/W2153037643","https://openalex.org/W2187511301","https://openalex.org/W2317666265","https://openalex.org/W2328852542","https://openalex.org/W2415733620","https://openalex.org/W2419096452","https://openalex.org/W2441930056","https://openalex.org/W2583222825","https://openalex.org/W2776104132","https://openalex.org/W2787499590","https://openalex.org/W2884283921","https://openalex.org/W2892249423","https://openalex.org/W2894250546","https://openalex.org/W2985956097"],"related_works":["https://openalex.org/W901220368","https://openalex.org/W1271656581","https://openalex.org/W2460409130","https://openalex.org/W3217613762","https://openalex.org/W2064500660","https://openalex.org/W2912294337","https://openalex.org/W2130251106","https://openalex.org/W154338643","https://openalex.org/W2892249423","https://openalex.org/W2104626090"],"abstract_inverted_index":{"As":[0],"in":[1,33,60,64,70,77,87,103,157,176,224],"other":[2,229],"excitable":[3],"tissues,":[4],"two":[5,114,204],"classes":[6],"of":[7,11,17,30,37,49,83,89,117,120,126,148,179,203,221,228],"electrical":[8,81,106,222],"signals":[9],"are":[10],"fundamental":[12],"importance":[13],"to":[14,54,79,98,113],"the":[15,28,38,47,58,80,84,99,123,130,146,180,200,210,225],"functioning":[16,223],"smooth":[18,71,109,159,201,226],"muscles:":[19],"junction":[20,66,153],"potentials,":[21,44],"which":[22,45,135],"arise":[23],"from":[24,108],"neurotransmission":[25],"and":[26,40,51,63,68,86,111,129,150,155,170,191,213],"represent":[27,46],"initiation":[29],"excitation":[31,50],"(or":[32],"some":[34,178],"instances":[35],"inhibition)":[36],"tissue,":[39],"spikes":[41,69,156],"or":[42],"action":[43],"accomplishment":[48],"lead":[52],"on":[53,152,188,219],"contractile":[55],"activity.":[56],"Unlike":[57],"case":[59],"skeletal":[61],"muscle":[62,72],"neurons,":[65],"potentials":[67,154],"have":[73,165],"been":[74],"poorly":[75],"understood":[76],"relation":[78],"properties":[82],"tissue":[85],"terms":[88],"their":[90,137],"spatiotemporal":[91],"spread":[92],"within":[93],"it.":[94],"This":[95],"owes":[96],"principally":[97],"experimental":[100],"difficulties":[101],"involved":[102],"making":[104],"precise":[105],"recordings":[107],"muscles":[110,202,227],"also":[112,217],"inherent":[115],"features":[116,220],"this":[118,142],"class":[119],"muscle,":[121,160],"ie,":[122],"syncytial":[124,158],"organization":[125],"its":[127],"cells":[128],"distributed":[131],"innervation":[132],"they":[133],"receive,":[134],"renders":[136],"biophysical":[138],"analysis":[139,193],"problematic.":[140],"In":[141],"review,":[143],"we":[144],"outline":[145],"development":[147],"hypotheses":[149],"knowledge":[151],"showing":[161],"how":[162,171],"our":[163],"concepts":[164],"frequently":[166],"undergone":[167],"radical":[168],"changes":[169],"recent":[172],"developments":[173],"hold":[174],"promise":[175],"unraveling":[177],"many":[181],"puzzles":[182],"that":[183],"remain.":[184],"We":[185,195],"focus":[186],"especially":[187],"computational":[189],"models":[190],"signal":[192],"approaches.":[194],"take":[196],"as":[197],"illustrative":[198],"examples":[199],"organs":[205],"with":[206],"distinct":[207],"functional":[208],"characteristics,":[209],"vas":[211],"deferens":[212],"urinary":[214],"bladder,":[215],"while":[216],"touching":[218],"organs.":[230]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-01-25T00:00:00"}
