{"id":"https://openalex.org/W2909798293","doi":"https://doi.org/10.1371/journal.pone.0210798","title":"Oral Candida administration in a Clostridium difficile mouse model worsens disease severity but is attenuated by Bifidobacterium","display_name":"Oral Candida administration in a Clostridium difficile mouse model worsens disease severity but is attenuated by Bifidobacterium","publication_year":2019,"publication_date":"2019-01-15","ids":{"openalex":"https://openalex.org/W2909798293","doi":"https://doi.org/10.1371/journal.pone.0210798","mag":"2909798293","pmid":"https://pubmed.ncbi.nlm.nih.gov/30645630","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6333342"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0210798","doi":"https://doi.org/10.1371/journal.pone.0210798","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0210798","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0210798&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0210798&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028932102","display_name":"Wimonrat Panpetch","orcid":"https://orcid.org/0000-0002-0455-6757","observed_orcids":["https://orcid.org/0000-0002-0455-6757"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Wimonrat Panpetch","raw_affiliation_strings":["Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025567689","display_name":"Naraporn Somboonna","orcid":"https://orcid.org/0000-0002-7830-3509","observed_orcids":["https://orcid.org/0000-0002-7830-3509"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Naraporn Somboonna","raw_affiliation_strings":["Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074742279","display_name":"Matanee Palasuk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Matanee Palasuk","raw_affiliation_strings":["Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062722167","display_name":"Pratsanee Hiengrach","orcid":"https://orcid.org/0009-0004-7212-2522","observed_orcids":["https://orcid.org/0009-0004-7212-2522"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Pratsanee Hiengrach","raw_affiliation_strings":["Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014252085","display_name":"Malcolm Finkelman","orcid":"https://orcid.org/0000-0003-2315-9797","observed_orcids":["https://orcid.org/0000-0003-2315-9797"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Malcolm Finkelman","raw_affiliation_strings":["Associates of Cape Cod, Inc., East Falmouth, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Associates of Cape Cod, Inc., East Falmouth, MA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037456329","display_name":"Somying Tumwasorn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Somying Tumwasorn","raw_affiliation_strings":["Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016611718","display_name":"Asada Leelahavanichkul","orcid":"https://orcid.org/0000-0002-5566-6403","observed_orcids":["https://orcid.org/0000-0002-5566-6403"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Asada Leelahavanichkul","raw_affiliation_strings":["Center of Excellence in Immunology and Immune-mediated Diseases, Department of Microbiology, Chulalongkorn University, Bangkok, Thailand","Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":"https://orcid.org/0000-0002-5566-6403","affiliations":[{"raw_affiliation_string":"Center of Excellence in Immunology and Immune-mediated Diseases, Department of Microbiology, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]},{"raw_affiliation_string":"Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5016611718"],"corresponding_institution_ids":["https://openalex.org/I158708052"],"apc_list":{"value":1595,"currency":"USD","value_usd":1595},"apc_paid":{"value":1595,"currency":"USD","value_usd":1595},"fwci":9.1304,"has_fulltext":true,"cited_by_count":69,"citation_normalized_percentile":{"value":0.98852325,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"14","issue":"1","first_page":"e0210798","last_page":"e0210798"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clostridium-difficile-infection","display_name":"Clostridium difficile infection","score":0.9990000128746033},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.9909999966621399},{"id":"https://openalex.org/keywords/bifidobacterium","display_name":"Bifidobacterium","score":0.8859999775886536},{"id":"https://openalex.org/keywords/gut-mycobiome","display_name":"gut mycobiome","score":0.8389999866485596},{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":0.6380000114440918},{"id":"https://openalex.org/keywords/gut-fungi","display_name":"gut fungi","score":0.4180000126361847},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.621999979019165},{"id":"https://openalex.org/keywords/intestinal-inflammation","display_name":"intestinal inflammation","score":0.5019999742507935},{"id":"https://openalex.org/keywords/interleukin-8","display_name":"interleukin-8","score":0.722000002861023},{"id":"https://openalex.org/keywords/leaky-gut","display_name":"leaky gut","score":0.6110000014305115},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.44200000166893005}],"concepts":[{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7889872193336487},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.7697739601135254},{"id":"https://openalex.org/C2994496256","wikidata":"https://www.wikidata.org/wiki/Q27031090","display_name":"Clostridium difficile","level":3,"score":0.719515860080719},{"id":"https://openalex.org/C2780305828","wikidata":"https://www.wikidata.org/wiki/Q132656","display_name":"Bifidobacterium","level":4,"score":0.6221643686294556},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6206867098808289},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.6010846495628357},{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.5797722339630127},{"id":"https://openalex.org/C2777165150","wikidata":"https://www.wikidata.org/wiki/Q269334","display_name":"Dysbiosis","level":3,"score":0.5486973524093628},{"id":"https://openalex.org/C145081991","wikidata":"https://www.wikidata.org/wiki/Q2576388","display_name":"Corpus albicans","level":3,"score":0.5177768468856812},{"id":"https://openalex.org/C2777392542","wikidata":"https://www.wikidata.org/wiki/Q3174392","display_name":"Human feces","level":3,"score":0.43131375312805176},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.37828773260116577},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.35706228017807007},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.3008444905281067},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.13128986954689026},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000072761","descriptor_name":"Mycobiome","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001644","descriptor_name":"Bifidobacterium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D003015","descriptor_name":"Clostridium Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D003015","descriptor_name":"Clostridium Infections","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010539","descriptor_name":"Permeability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016209","descriptor_name":"Interleukin-8","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D018938","descriptor_name":"Caco-2 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019073","descriptor_name":"HT29 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pone.0210798","doi":"https://doi.org/10.1371/journal.pone.0210798","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0210798","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0210798&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5336437","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6333342","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:30645630","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30645630","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6333342","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6333342/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:312e61923ecc4957acc1366566f4e602","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/312e61923ecc4957acc1366566f4e602","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 14, Iss 1, p e0210798 (2019)","raw_type":"article"},{"id":"doi:10.60692/7v92s-23643","doi":"https://doi.org/10.60692/7v92s-23643","is_oa":true,"landing_page_url":"https://doi.org/10.60692/7v92s-23643","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.60692/mmmnp-7hj89","doi":"https://doi.org/10.60692/mmmnp-7hj89","is_oa":true,"landing_page_url":"https://doi.org/10.60692/mmmnp-7hj89","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0210798","doi":"https://doi.org/10.1371/journal.pone.0210798","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0210798","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0210798&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1354990314","display_name":null,"funder_award_id":"RSA-6080023","funder_id":"https://openalex.org/F4320322614","funder_display_name":"Thailand Research Fund"},{"id":"https://openalex.org/G1982288036","display_name":null,"funder_award_id":"RES_61_202_30_022","funder_id":"https://openalex.org/F4320322614","funder_display_name":"Thailand Research Fund"},{"id":"https://openalex.org/G2616210410","display_name":null,"funder_award_id":"760001-HR","funder_id":"https://openalex.org/F4320321557","funder_display_name":"Chulalongkorn University"}],"funders":[{"id":"https://openalex.org/F4320321557","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58"},{"id":"https://openalex.org/F4320322614","display_name":"Thailand Research Fund","ror":"https://ror.org/03gd1bh37"},{"id":"https://openalex.org/F4320334939","display_name":"Faculty of Medicine, Chulalongkorn University","ror":"https://ror.org/028wp3y58"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2909798293.pdf","grobid_xml":"https://content.openalex.org/works/W2909798293.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W97158386","https://openalex.org/W1716352502","https://openalex.org/W1973326673","https://openalex.org/W1979853218","https://openalex.org/W1982994377","https://openalex.org/W1983938401","https://openalex.org/W2041040328","https://openalex.org/W2047744186","https://openalex.org/W2051839115","https://openalex.org/W2093664169","https://openalex.org/W2094143002","https://openalex.org/W2102459023","https://openalex.org/W2105720615","https://openalex.org/W2108657897","https://openalex.org/W2114238421","https://openalex.org/W2115414596","https://openalex.org/W2115440327","https://openalex.org/W2115980431","https://openalex.org/W2129137198","https://openalex.org/W2134158047","https://openalex.org/W2135959117","https://openalex.org/W2139057316","https://openalex.org/W2156911088","https://openalex.org/W2159745814","https://openalex.org/W2161441154","https://openalex.org/W2164052164","https://openalex.org/W2171727519","https://openalex.org/W2242390630","https://openalex.org/W2318911370","https://openalex.org/W2411685249","https://openalex.org/W2511712013","https://openalex.org/W2539316870","https://openalex.org/W2552166980","https://openalex.org/W2563797091","https://openalex.org/W2605052214","https://openalex.org/W2613237870","https://openalex.org/W2616380171","https://openalex.org/W2740005395","https://openalex.org/W2766099790","https://openalex.org/W2793256216"],"related_works":["https://openalex.org/W2799450956","https://openalex.org/W4382010727","https://openalex.org/W4293056731","https://openalex.org/W2937181440","https://openalex.org/W4408481444","https://openalex.org/W2889801898","https://openalex.org/W3038317064","https://openalex.org/W4384205152","https://openalex.org/W2921820611","https://openalex.org/W4389395223"],"abstract_inverted_index":{"Gut":[0,243],"fungi":[1],"may":[2,49,67,236,255],"influence":[3],"the":[4,15,22,28,46,51,108,127,130,186,190,234,239],"course":[5],"of":[6,45,53,110,129,189,219,225],"Clostridium":[7,226],"difficile":[8,55,100,132,158,165,172,192,214,227,251],"infection":[9,76,133,228],"either":[10],"positively":[11],"or":[12,38,159],"negatively":[13],"for":[14,81],"host.":[16],"Fungi":[17],"are":[18],"not":[19],"prominent":[20],"in":[21,35,40,65,161,205,233,247],"mouse":[23,223],"gut,":[24,66],"and":[25,62,77,90,146,148,178,254],"C.":[26,54,60,63,92,99,123,131,157,164,171,191,210,213,230,250],"albicans,":[27],"major":[29],"human":[30,75,180,240],"gastrointestinal":[31],"commensal":[32],"yeast,":[33],"is":[34,43,252],"low":[36],"abundance":[37],"absent":[39],"mice.":[41],"Bifidobacterium":[42,184],"one":[44],"probiotics":[47],"that":[48,71],"attenuate":[50],"severity":[52,128,188,198],"infection.":[56],"Inflammatory":[57],"synergy":[58],"between":[59],"albicans":[61,93,124,211,231],"difficile,":[64],"provide":[68],"a":[69,222],"state":[70],"more":[72,79],"closely":[73],"resembles":[74],"be":[78],"suitable":[80],"testing":[82],"probiotic":[83],"effects.":[84],"We":[85],"performed":[86],"fecal":[87,120,156],"mycobiota":[88],"analysis":[89,106],"administered":[91],"at":[94],"1":[95],"day":[96],"prior":[97],"to":[98],"dosing.":[101],"Fecal":[102],"eukaryotic":[103],"18S":[104],"rDNA":[105],"demonstrated":[107],"presence":[109],"Ascomycota,":[111],"specifically,":[112],"Candida":[113,168,194,203],"spp.,":[114],"after":[115],"oral":[116],"antibiotics,":[117],"despite":[118],"negative":[119],"fungal":[121,244],"culture.":[122],"administration":[125],"enhanced":[126],"model":[134,224,238],"as":[135],"determined":[136],"by":[137],"mortality":[138],"rate,":[139],"weight":[140],"loss,":[141],"gut":[142,209,235],"leakage":[143],"(FITC-dextran":[144],"assay),":[145],"serum":[147],"intestinal":[149,181],"tissue":[150],"cytokines.":[151],"This":[152],"occurred":[153],"without":[154],"increased":[155,173],"bacteremia,":[160],"comparison":[162],"with":[163,170,201,229,249],"gavage":[166],"alone.":[167],"lysate":[169],"IL-8":[174],"production":[175],"from":[176],"HT-29":[177],"Caco-2":[179],"epithelial":[182],"cell-lines.":[183],"attenuated":[185],"disease":[187],"plus":[193],"model.":[195],"The":[196],"reduced":[197],"was":[199],"associated":[200],"decreased":[202],"burdens":[204],"feces.":[206],"In":[207],"conclusion,":[208],"worsened":[212],"infection,":[215],"possibly":[216],"through":[217],"exacerbation":[218],"inflammation.":[220],"Hence,":[221],"present":[232],"better":[237],"patient":[241],"condition.":[242],"mycobiome":[245],"investigation":[246],"patients":[248],"warranted":[253],"suggest":[256],"therapeutic":[257],"targets.":[258]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-01-25T00:00:00"}