{"id":"https://openalex.org/W2909554288","doi":"https://doi.org/10.1136/annrheumdis-2018-eular.6579","title":"AB0246 Genetic variability with toll-like receptor 10 affects susceptibility to rheumatoid arthritis and modulates response to biological treatment","display_name":"AB0246 Genetic variability with toll-like receptor 10 affects susceptibility to rheumatoid arthritis and modulates response to biological treatment","publication_year":2018,"publication_date":"2018-06-01","ids":{"openalex":"https://openalex.org/W2909554288","doi":"https://doi.org/10.1136/annrheumdis-2018-eular.6579","mag":"2909554288"},"language":"en","primary_location":{"id":"doi:10.1136/annrheumdis-2018-eular.6579","doi":"https://doi.org/10.1136/annrheumdis-2018-eular.6579","is_oa":true,"landing_page_url":"https://doi.org/10.1136/annrheumdis-2018-eular.6579","pdf_url":"https://ard.bmj.com/content/annrheumdis/77/Suppl_2/1305.1.full.pdf","source":{"id":"https://openalex.org/S25650217","display_name":"Annals of the Rheumatic Diseases","issn_l":"0003-4967","issn":["0003-4967","1468-2060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the Rheumatic Diseases","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ard.bmj.com/content/annrheumdis/77/Suppl_2/1305.1.full.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071988895","display_name":"Barbara Wysocza\u0144ska","orcid":"https://orcid.org/0000-0002-7554-3208","observed_orcids":["https://orcid.org/0000-0002-7554-3208"]},"institutions":[{"id":"https://openalex.org/I4210163977","display_name":"Ludwik Hirszfeld Institute of Immunology and Experimental Therapy","ror":"https://ror.org/05b7p8k90","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210163977","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"B. Wysoczanska","raw_affiliation_strings":["Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences","institution_ids":["https://openalex.org/I4210163977","https://openalex.org/I99542240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072847615","display_name":"Jerzy \u015awierkot","orcid":"https://orcid.org/0000-0003-3606-173X","observed_orcids":["https://orcid.org/0000-0003-3606-173X"]},"institutions":[{"id":"https://openalex.org/I219388962","display_name":"University of Wroc\u0142aw","ror":"https://ror.org/00yae6e25","country_code":"PL","type":"education","lineage":["https://openalex.org/I219388962"]},{"id":"https://openalex.org/I385303915","display_name":"Wroclaw Medical University","ror":"https://ror.org/01qpw1b93","country_code":"PL","type":"education","lineage":["https://openalex.org/I385303915"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"J. Swierkot","raw_affiliation_strings":["Department of Rheumatology and Internal Medicine, Medical University, Wroclaw"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology and Internal Medicine, Medical University, Wroclaw","institution_ids":["https://openalex.org/I219388962","https://openalex.org/I385303915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066059136","display_name":"Mateusz Puchala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210163977","display_name":"Ludwik Hirszfeld Institute of Immunology and Experimental Therapy","ror":"https://ror.org/05b7p8k90","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210163977","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"M. Puchala","raw_affiliation_strings":["Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences","institution_ids":["https://openalex.org/I4210163977","https://openalex.org/I99542240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030799484","display_name":"Katarzyna Kolossa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3019271933","display_name":"Nicolaus Copernicus University","ror":"https://ror.org/0102mm775","country_code":"PL","type":"education","lineage":["https://openalex.org/I3019271933"]},{"id":"https://openalex.org/I4210148386","display_name":"Collegium Medicum in Bydgoszcz","ror":"https://ror.org/04c5jwj47","country_code":"PL","type":"education","lineage":["https://openalex.org/I3019271933","https://openalex.org/I4210148386"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"K. Kolossa","raw_affiliation_strings":["Department of Rheumatology and Connective Tissue Diseases, Collegium Medicum of Nicolaus Copernicus University, Bydgoszcz, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology and Connective Tissue Diseases, Collegium Medicum of Nicolaus Copernicus University, Bydgoszcz, Poland","institution_ids":["https://openalex.org/I3019271933","https://openalex.org/I4210148386"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032940273","display_name":"S\u0142awomir Jeka","orcid":"https://orcid.org/0000-0003-2766-8046","observed_orcids":["https://orcid.org/0000-0003-2766-8046"]},"institutions":[{"id":"https://openalex.org/I3019271933","display_name":"Nicolaus Copernicus University","ror":"https://ror.org/0102mm775","country_code":"PL","type":"education","lineage":["https://openalex.org/I3019271933"]},{"id":"https://openalex.org/I4210148386","display_name":"Collegium Medicum in Bydgoszcz","ror":"https://ror.org/04c5jwj47","country_code":"PL","type":"education","lineage":["https://openalex.org/I3019271933","https://openalex.org/I4210148386"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"S. Jeka","raw_affiliation_strings":["Department of Rheumatology and Connective Tissue Diseases, Collegium Medicum of Nicolaus Copernicus University, Bydgoszcz, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology and Connective Tissue Diseases, Collegium Medicum of Nicolaus Copernicus University, Bydgoszcz, Poland","institution_ids":["https://openalex.org/I3019271933","https://openalex.org/I4210148386"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007364793","display_name":"Piotr Wiland","orcid":"https://orcid.org/0000-0001-9999-0267","observed_orcids":["https://orcid.org/0000-0001-9999-0267"]},"institutions":[{"id":"https://openalex.org/I219388962","display_name":"University of Wroc\u0142aw","ror":"https://ror.org/00yae6e25","country_code":"PL","type":"education","lineage":["https://openalex.org/I219388962"]},{"id":"https://openalex.org/I385303915","display_name":"Wroclaw Medical University","ror":"https://ror.org/01qpw1b93","country_code":"PL","type":"education","lineage":["https://openalex.org/I385303915"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"P. Wiland","raw_affiliation_strings":["Department of Rheumatology and Internal Medicine, Medical University, Wroclaw"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology and Internal Medicine, Medical University, Wroclaw","institution_ids":["https://openalex.org/I219388962","https://openalex.org/I385303915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091888669","display_name":"Katarzyna Bogunia\u2010Kubik","orcid":"https://orcid.org/0000-0001-9744-0376","observed_orcids":["https://orcid.org/0000-0001-9744-0376"]},"institutions":[{"id":"https://openalex.org/I4210163977","display_name":"Ludwik Hirszfeld Institute of Immunology and Experimental Therapy","ror":"https://ror.org/05b7p8k90","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210163977","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"K. Bogunia-Kubik","raw_affiliation_strings":["Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences","institution_ids":["https://openalex.org/I4210163977","https://openalex.org/I99542240"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4870,"currency":"USD","value_usd":4870},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"77","issue":null,"first_page":"1305","last_page":"1305"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.8579999804496765},{"id":"https://openalex.org/keywords/tlr10","display_name":"TLR10","score":0.9900000095367432},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.8289999961853027},{"id":"https://openalex.org/keywords/tnf-alpha-inhibitors","display_name":"TNF-alpha inhibitors","score":0.8029999732971191},{"id":"https://openalex.org/keywords/rheumatoid-factor","display_name":"rheumatoid factor","score":0.8209999799728394},{"id":"https://openalex.org/keywords/anti-citrullinated-protein-antibodies","display_name":"anti-citrullinated protein antibodies","score":0.8769999742507935},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8209999799728394},{"id":"https://openalex.org/keywords/disease-activity","display_name":"disease activity","score":0.6890000104904175},{"id":"https://openalex.org/keywords/remission","display_name":"remission","score":0.8840000033378601}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8532264232635498},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.7924726009368896},{"id":"https://openalex.org/C67636389","wikidata":"https://www.wikidata.org/wiki/Q784237","display_name":"Genetic predisposition","level":3,"score":0.5848966836929321},{"id":"https://openalex.org/C2776232647","wikidata":"https://www.wikidata.org/wiki/Q702883","display_name":"Rheumatoid factor","level":3,"score":0.5765191316604614},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.570192277431488},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.552779495716095},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5404208302497864},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5322639346122742},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.42450961470603943},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3729678988456726},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3292948007583618},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16183337569236755},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11812403798103333},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07657164335250854},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1136/annrheumdis-2018-eular.6579","doi":"https://doi.org/10.1136/annrheumdis-2018-eular.6579","is_oa":true,"landing_page_url":"https://doi.org/10.1136/annrheumdis-2018-eular.6579","pdf_url":"https://ard.bmj.com/content/annrheumdis/77/Suppl_2/1305.1.full.pdf","source":{"id":"https://openalex.org/S25650217","display_name":"Annals of the Rheumatic Diseases","issn_l":"0003-4967","issn":["0003-4967","1468-2060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the Rheumatic Diseases","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1136/annrheumdis-2018-eular.6579","doi":"https://doi.org/10.1136/annrheumdis-2018-eular.6579","is_oa":true,"landing_page_url":"https://doi.org/10.1136/annrheumdis-2018-eular.6579","pdf_url":"https://ard.bmj.com/content/annrheumdis/77/Suppl_2/1305.1.full.pdf","source":{"id":"https://openalex.org/S25650217","display_name":"Annals of the Rheumatic Diseases","issn_l":"0003-4967","issn":["0003-4967","1468-2060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the Rheumatic Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2909554288.pdf","grobid_xml":"https://content.openalex.org/works/W2909554288.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2017535503","https://openalex.org/W4400087430","https://openalex.org/W1865497936","https://openalex.org/W2724884594","https://openalex.org/W2047021787","https://openalex.org/W2902960175","https://openalex.org/W4220956206","https://openalex.org/W4214893751","https://openalex.org/W2610950813","https://openalex.org/W2021359684"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-08T07:41:39.490200","created_date":"2019-01-25T00:00:00"}