{"id":"https://openalex.org/W2909484229","doi":"https://doi.org/10.1080/00016357.2018.1533142","title":"In vitro treatment of Enterococcus faecalis with calcium hydroxide impairs phagocytosis by human macrophages","display_name":"In vitro treatment of Enterococcus faecalis with calcium hydroxide impairs phagocytosis by human macrophages","publication_year":2019,"publication_date":"2019-01-08","ids":{"openalex":"https://openalex.org/W2909484229","doi":"https://doi.org/10.1080/00016357.2018.1533142","mag":"2909484229","pmid":"https://pubmed.ncbi.nlm.nih.gov/30618320"},"language":"en","primary_location":{"id":"doi:10.1080/00016357.2018.1533142","doi":"https://doi.org/10.1080/00016357.2018.1533142","is_oa":true,"landing_page_url":"https://doi.org/10.1080/00016357.2018.1533142","pdf_url":null,"source":{"id":"https://openalex.org/S42091764","display_name":"Acta Odontologica Scandinavica","issn_l":"0001-6357","issn":["0001-6357","1502-3850"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Odontologica Scandinavica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1080/00016357.2018.1533142","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074272463","display_name":"Jos\u00e9 Ponce","orcid":"https://orcid.org/0000-0001-8729-669X","observed_orcids":["https://orcid.org/0000-0001-8729-669X"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Burgos Ponce","raw_affiliation_strings":["Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil;"],"raw_orcid":"https://orcid.org/0000-0001-8729-669X","affiliations":[{"raw_affiliation_string":"Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil;","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017980761","display_name":"Raquel Zanin Midena","orcid":"https://orcid.org/0000-0001-5460-1248","observed_orcids":["https://orcid.org/0000-0001-5460-1248"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Raquel Zanin Midena","raw_affiliation_strings":["Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil;"],"raw_orcid":"https://orcid.org/0000-0001-5460-1248","affiliations":[{"raw_affiliation_string":"Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil;","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077530403","display_name":"Karen Henriette Pinke","orcid":"https://orcid.org/0000-0001-8716-1250","observed_orcids":["https://orcid.org/0000-0001-8716-1250"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Karen Henriette Pinke","raw_affiliation_strings":["Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil;"],"raw_orcid":"https://orcid.org/0000-0001-8716-1250","affiliations":[{"raw_affiliation_string":"Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil;","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031562977","display_name":"Paulo Henrique Weckwerth","orcid":"https://orcid.org/0000-0002-4798-8162","observed_orcids":["https://orcid.org/0000-0002-4798-8162"]},"institutions":[{"id":"https://openalex.org/I4210109090","display_name":"Universidade Sagrado Cora\u00e7\u00e3o","ror":"https://ror.org/01thzqc78","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210109090"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Paulo Henrique Weckwerth","raw_affiliation_strings":["Universidade do Sagrado Cora\u00e7\u00e3o, Pro-Rectory of Research and Post Graduation, Bauru, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-4798-8162","affiliations":[{"raw_affiliation_string":"Universidade do Sagrado Cora\u00e7\u00e3o, Pro-Rectory of Research and Post Graduation, Bauru, Brazil","institution_ids":["https://openalex.org/I4210109090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053396883","display_name":"Flaviana Bombarda de Andrade","orcid":"https://orcid.org/0000-0002-1238-2160","observed_orcids":["https://orcid.org/0000-0002-1238-2160"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Flaviana Bombarda de Andrade","raw_affiliation_strings":["Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil;"],"raw_orcid":"https://orcid.org/0000-0002-1238-2160","affiliations":[{"raw_affiliation_string":"Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil;","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023688474","display_name":"Vanessa Soares Lara","orcid":"https://orcid.org/0000-0003-1986-0003","observed_orcids":["https://orcid.org/0000-0003-1986-0003"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Vanessa Soares Lara","raw_affiliation_strings":["Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil;"],"raw_orcid":"https://orcid.org/0000-0003-1986-0003","affiliations":[{"raw_affiliation_string":"Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of S\u00e3o Paulo, Bauru, Brazil;","institution_ids":["https://openalex.org/I17974374"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5023688474"],"corresponding_institution_ids":["https://openalex.org/I17974374"],"apc_list":null,"apc_paid":null,"fwci":0.8156,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.70527313,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"77","issue":"2","first_page":"158","last_page":"163"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10536","display_name":"Endodontics and Root Canal Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10536","display_name":"Endodontics and Root Canal Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enterococcus-faecalis","display_name":"Enterococcus faecalis","score":1.0},{"id":"https://openalex.org/keywords/calcium-hydroxide","display_name":"calcium hydroxide","score":0.9729999899864197},{"id":"https://openalex.org/keywords/phagocytosis","display_name":"phagocytosis","score":0.828000009059906},{"id":"https://openalex.org/keywords/monocyte-derived-macrophages","display_name":"monocyte-derived macrophages","score":0.9200000166893005},{"id":"https://openalex.org/keywords/nitric-oxide-production","display_name":"nitric oxide production","score":0.9039999842643738},{"id":"https://openalex.org/keywords/alkaline-stress","display_name":"alkaline stress","score":0.9649999737739563},{"id":"https://openalex.org/keywords/endodontic-infection","display_name":"root canal infection","score":0.7940000295639038},{"id":"https://openalex.org/keywords/bacterial-cell-wall","display_name":"bacterial cell wall","score":0.5799999833106995},{"id":"https://openalex.org/keywords/root-canal-treatment","display_name":"endodontic treatment","score":0.6209999918937683},{"id":"https://openalex.org/keywords/bacterial-persistence","display_name":"bacterial persistence","score":0.6480000019073486},{"id":"https://openalex.org/keywords/urinary-isolates","display_name":"urine isolates","score":0.6200000047683716}],"concepts":[{"id":"https://openalex.org/C2779895986","wikidata":"https://www.wikidata.org/wiki/Q140014","display_name":"Enterococcus faecalis","level":4,"score":0.9267648458480835},{"id":"https://openalex.org/C160448771","wikidata":"https://www.wikidata.org/wiki/Q184726","display_name":"Phagocytosis","level":2,"score":0.8095557689666748},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7635490298271179},{"id":"https://openalex.org/C2779747767","wikidata":"https://www.wikidata.org/wiki/Q848390","display_name":"Root canal","level":2,"score":0.6978693604469299},{"id":"https://openalex.org/C2779102032","wikidata":"https://www.wikidata.org/wiki/Q342717","display_name":"Acridine orange","level":3,"score":0.6068395376205444},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4888860285282135},{"id":"https://openalex.org/C2779563543","wikidata":"https://www.wikidata.org/wiki/Q182849","display_name":"Calcium hydroxide","level":2,"score":0.4847390353679657},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47139909863471985},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3812906742095947},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.18495634198188782},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17473459243774414},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.1277734339237213},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11469241976737976},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.07309341430664062},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000891","descriptor_name":"Anti-Infective Agents, Local","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000891","descriptor_name":"Anti-Infective Agents, Local","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002126","descriptor_name":"Calcium Hydroxide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D002126","descriptor_name":"Calcium Hydroxide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003786","descriptor_name":"Dental Pulp Cavity","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012388","descriptor_name":"Root Canal Irrigants","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D012388","descriptor_name":"Root Canal Irrigants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D012390","descriptor_name":"Root Canal Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013293","descriptor_name":"Enterococcus faecalis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D016908","descriptor_name":"Gram-Positive Bacterial Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1080/00016357.2018.1533142","doi":"https://doi.org/10.1080/00016357.2018.1533142","is_oa":true,"landing_page_url":"https://doi.org/10.1080/00016357.2018.1533142","pdf_url":null,"source":{"id":"https://openalex.org/S42091764","display_name":"Acta Odontologica Scandinavica","issn_l":"0001-6357","issn":["0001-6357","1502-3850"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Odontologica Scandinavica","raw_type":"journal-article"},{"id":"pmid:30618320","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30618320","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta odontologica Scandinavica","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1080/00016357.2018.1533142","doi":"https://doi.org/10.1080/00016357.2018.1533142","is_oa":true,"landing_page_url":"https://doi.org/10.1080/00016357.2018.1533142","pdf_url":null,"source":{"id":"https://openalex.org/S42091764","display_name":"Acta Odontologica Scandinavica","issn_l":"0001-6357","issn":["0001-6357","1502-3850"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Odontologica Scandinavica","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W837152655","https://openalex.org/W1541188679","https://openalex.org/W1606795265","https://openalex.org/W1837955074","https://openalex.org/W1840651490","https://openalex.org/W1842746926","https://openalex.org/W1904914812","https://openalex.org/W1968516520","https://openalex.org/W1973187647","https://openalex.org/W1988808211","https://openalex.org/W2007588226","https://openalex.org/W2012992792","https://openalex.org/W2015721638","https://openalex.org/W2017306058","https://openalex.org/W2023469843","https://openalex.org/W2024596121","https://openalex.org/W2051780555","https://openalex.org/W2051854348","https://openalex.org/W2054432287","https://openalex.org/W2055224823","https://openalex.org/W2059810047","https://openalex.org/W2061222339","https://openalex.org/W2064763603","https://openalex.org/W2066847273","https://openalex.org/W2067068630","https://openalex.org/W2080747341","https://openalex.org/W2082849546","https://openalex.org/W2111034501","https://openalex.org/W2116907180","https://openalex.org/W2117438470","https://openalex.org/W2118730086","https://openalex.org/W2119932234","https://openalex.org/W2132736261","https://openalex.org/W2138134476","https://openalex.org/W2165658595","https://openalex.org/W2171375246","https://openalex.org/W2190401727","https://openalex.org/W2191219252","https://openalex.org/W2220370032","https://openalex.org/W2298886697","https://openalex.org/W2301495893","https://openalex.org/W2601289384","https://openalex.org/W2653058753","https://openalex.org/W2700563998","https://openalex.org/W2730284991","https://openalex.org/W2751641921","https://openalex.org/W2765537442"],"related_works":["https://openalex.org/W3183748747","https://openalex.org/W4415264394","https://openalex.org/W1842746926","https://openalex.org/W3211843680","https://openalex.org/W7106277910","https://openalex.org/W4378906487","https://openalex.org/W2190401727","https://openalex.org/W3197613318","https://openalex.org/W1984907255","https://openalex.org/W2151583723"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Monocyte-derived":[1],"macrophages":[2],"(MDMs)":[3],"ability":[4,134],"to":[5,21,135,162],"phagocytize":[6],"and":[7,42,62,125],"produce":[8],"nitric":[9],"oxide":[10],"(NO)":[11],"was":[12,53,65,93],"tested":[13],"against":[14],"root-canal":[15],"strains":[16,25,80,98,142,151],"of":[17,50,77,96,157],"Enterococcus":[18,35],"faecalis":[19,36,79,159],"submitted":[20],"alkaline":[22],"stress.":[23],"Root-canal":[24],"were":[26,37],"also":[27],"compared":[28,149],"with":[29,39,150,171],"urine":[30,101],"Enterococci.":[31],"MATERIALS":[32],"AND":[33,70],"METHODS:":[34],"stressed":[38],"alkaline-BHI":[40],"broth":[41],"incubated":[43],"in":[44,67,83,112,165],"vitro":[45],"at":[46],"a":[47,87],"cell/bacteria":[48],"ratio":[49],"1:5.":[51],"Phagocytosis":[52],"analyzed":[54],"by":[55,127,146],"fluorescence":[56],"microscopy":[57],"using":[58],"acridine":[59],"orange":[60],"stain,":[61],"NO":[63,91,105,137],"concentration":[64],"measured":[66],"supernatants.":[68],"RESULTS":[69],"CONCLUSIONS:":[71],"Alkaline-stress":[72],"significantly":[73],"impaired":[74,155],"MDMs":[75,128],"phagocytosis":[76,156],"E.":[78,158],"analyzed,":[81],"except":[82],"ATCC4083":[84],"isolated":[85],"from":[86,152],"pulpless":[88],"tooth,":[89],"but":[90,129],"production":[92],"unchanged.":[94],"Comparison":[95],"different":[97,144],"showed":[99],"the":[100,113],"isolate":[102],"had":[103],"higher":[104],"levels":[106],"than":[107],"root":[108,140,166],"canal":[109,141,167],"strains.":[110],"Alterations":[111],"bacterial":[114],"cell":[115],"wall":[116],"structures":[117],"after":[118],"alkaline-stress":[119],"possibly":[120],"made":[121],"bacteria":[122],"less":[123],"recognizable":[124],"phagocytized":[126],"did":[130],"not":[131],"affect":[132],"their":[133,163],"activate":[136],"production.":[138],"Furthermore,":[139],"elicited":[143],"responses":[145],"immune":[147],"cells":[148],"urine.":[153],"Clinically,":[154],"could":[160],"contribute":[161],"persistence":[164],"systems":[168],"previously":[169],"treated":[170],"calcium":[172],"hydroxide.":[173]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-01-25T00:00:00"}