{"id":"https://openalex.org/W2909293124","doi":"https://doi.org/10.1084/jem.20181102","title":"Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis","display_name":"Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis","publication_year":2019,"publication_date":"2019-01-15","ids":{"openalex":"https://openalex.org/W2909293124","doi":"https://doi.org/10.1084/jem.20181102","mag":"2909293124","pmid":"https://pubmed.ncbi.nlm.nih.gov/30647120","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6363424"},"language":"en","primary_location":{"id":"doi:10.1084/jem.20181102","doi":"https://doi.org/10.1084/jem.20181102","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.20181102","pdf_url":"https://rupress.org/jem/article-pdf/216/2/350/1171119/jem_20181102.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://rupress.org/jem/article-pdf/216/2/350/1171119/jem_20181102.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088259499","display_name":"Ludwig T. Weckbach","orcid":"https://orcid.org/0000-0002-0981-2246","observed_orcids":["https://orcid.org/0000-0002-0981-2246"]},"institutions":[{"id":"https://openalex.org/I3018771216","display_name":"LMU Klinikum","ror":"https://ror.org/02jet3w32","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4210127591","display_name":"German Centre for Cardiovascular Research","ror":"https://ror.org/031t5w623","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210127591","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I4405258122","display_name":"Institut f\u00fcr Chirurgische Forschung","ror":"https://ror.org/005506478","country_code":"DE","type":"facility","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405258122","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4405260491","display_name":"Institut f\u00fcr Kardiovaskul\u00e4re Physiologie und Pathophysiologie","ror":"https://ror.org/03tw5w184","country_code":"DE","type":"education","lineage":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Ludwig T. Weckbach","raw_affiliation_strings":["German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich, Germany 4","Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1","Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2","Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich, Germany 4","institution_ids":["https://openalex.org/I4210127591"]},{"raw_affiliation_string":"Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","institution_ids":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1","institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2","institution_ids":["https://openalex.org/I4405258122","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany","institution_ids":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007839501","display_name":"Ulrich Grabmaier","orcid":"https://orcid.org/0000-0002-2168-4232","observed_orcids":["https://orcid.org/0000-0002-2168-4232"]},"institutions":[{"id":"https://openalex.org/I3018771216","display_name":"LMU Klinikum","ror":"https://ror.org/02jet3w32","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4210127591","display_name":"German Centre for Cardiovascular Research","ror":"https://ror.org/031t5w623","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210127591","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ulrich Grabmaier","raw_affiliation_strings":["German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich, Germany 4","Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich, Germany 4","institution_ids":["https://openalex.org/I4210127591"]},{"raw_affiliation_string":"Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1","institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002927941","display_name":"A. Uhl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018771216","display_name":"LMU Klinikum","ror":"https://ror.org/02jet3w32","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4405258122","display_name":"Institut f\u00fcr Chirurgische Forschung","ror":"https://ror.org/005506478","country_code":"DE","type":"facility","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405258122","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4405260491","display_name":"Institut f\u00fcr Kardiovaskul\u00e4re Physiologie und Pathophysiologie","ror":"https://ror.org/03tw5w184","country_code":"DE","type":"education","lineage":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andreas Uhl","raw_affiliation_strings":["Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1","Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2","Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","institution_ids":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1","institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2","institution_ids":["https://openalex.org/I4405258122","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany","institution_ids":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010946942","display_name":"Sebastian Gess","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405258122","display_name":"Institut f\u00fcr Chirurgische Forschung","ror":"https://ror.org/005506478","country_code":"DE","type":"facility","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405258122","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4405260491","display_name":"Institut f\u00fcr Kardiovaskul\u00e4re Physiologie und Pathophysiologie","ror":"https://ror.org/03tw5w184","country_code":"DE","type":"education","lineage":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sebastian Gess","raw_affiliation_strings":["Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","institution_ids":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2","institution_ids":["https://openalex.org/I4405258122","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032564300","display_name":"Felicitas Boehm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405258122","display_name":"Institut f\u00fcr Chirurgische Forschung","ror":"https://ror.org/005506478","country_code":"DE","type":"facility","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405258122","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4405260491","display_name":"Institut f\u00fcr Kardiovaskul\u00e4re Physiologie und Pathophysiologie","ror":"https://ror.org/03tw5w184","country_code":"DE","type":"education","lineage":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Felicitas Boehm","raw_affiliation_strings":["Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","institution_ids":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2","institution_ids":["https://openalex.org/I4405258122","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011221188","display_name":"Annette Zehrer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405258122","display_name":"Institut f\u00fcr Chirurgische Forschung","ror":"https://ror.org/005506478","country_code":"DE","type":"facility","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405258122","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4405260491","display_name":"Institut f\u00fcr Kardiovaskul\u00e4re Physiologie und Pathophysiologie","ror":"https://ror.org/03tw5w184","country_code":"DE","type":"education","lineage":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Annette Zehrer","raw_affiliation_strings":["Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","institution_ids":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2","institution_ids":["https://openalex.org/I4405258122","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066251778","display_name":"Robert Pick","orcid":"https://orcid.org/0000-0001-9785-8481","observed_orcids":["https://orcid.org/0000-0001-9785-8481"]},"institutions":[{"id":"https://openalex.org/I4405258122","display_name":"Institut f\u00fcr Chirurgische Forschung","ror":"https://ror.org/005506478","country_code":"DE","type":"facility","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405258122","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4405260491","display_name":"Institut f\u00fcr Kardiovaskul\u00e4re Physiologie und Pathophysiologie","ror":"https://ror.org/03tw5w184","country_code":"DE","type":"education","lineage":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Robert Pick","raw_affiliation_strings":["Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","institution_ids":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2","institution_ids":["https://openalex.org/I4405258122","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023608201","display_name":"Melanie Salvermoser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405258122","display_name":"Institut f\u00fcr Chirurgische Forschung","ror":"https://ror.org/005506478","country_code":"DE","type":"facility","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405258122","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4405260491","display_name":"Institut f\u00fcr Kardiovaskul\u00e4re Physiologie und Pathophysiologie","ror":"https://ror.org/03tw5w184","country_code":"DE","type":"education","lineage":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Melanie Salvermoser","raw_affiliation_strings":["Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","institution_ids":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2","institution_ids":["https://openalex.org/I4405258122","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081272670","display_name":"Thomas Czermak","orcid":"https://orcid.org/0000-0002-1783-092X","observed_orcids":["https://orcid.org/0000-0002-1783-092X"]},"institutions":[{"id":"https://openalex.org/I3018771216","display_name":"LMU Klinikum","ror":"https://ror.org/02jet3w32","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas Czermak","raw_affiliation_strings":["Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1","institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001017179","display_name":"Joachim Pircher","orcid":"https://orcid.org/0000-0002-8890-0884","observed_orcids":["https://orcid.org/0000-0002-8890-0884"]},"institutions":[{"id":"https://openalex.org/I3018771216","display_name":"LMU Klinikum","ror":"https://ror.org/02jet3w32","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Joachim Pircher","raw_affiliation_strings":["Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1","institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045293439","display_name":"Noah B. Sorrelle","orcid":"https://orcid.org/0000-0002-4576-3912","observed_orcids":["https://orcid.org/0000-0002-4576-3912"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Noah Sorrelle","raw_affiliation_strings":["Hamon Center for Therapeutic Oncology Research, Division of Surgical Oncology, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 5"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hamon Center for Therapeutic Oncology Research, Division of Surgical Oncology, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 5","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034909181","display_name":"Mary M. Migliorini","orcid":"https://orcid.org/0000-0001-9167-7444","observed_orcids":["https://orcid.org/0000-0001-9167-7444"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Migliorini","raw_affiliation_strings":["Center for Vascular and Inflammatory Disease, Departments of Surgery and Physiology, University of Maryland School of Medicine, Baltimore, MD 6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Vascular and Inflammatory Disease, Departments of Surgery and Physiology, University of Maryland School of Medicine, Baltimore, MD 6","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049969799","display_name":"Dudley K. Strickland","orcid":"https://orcid.org/0000-0001-7526-5917","observed_orcids":["https://orcid.org/0000-0001-7526-5917"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dudley K. Strickland","raw_affiliation_strings":["Center for Vascular and Inflammatory Disease, Departments of Surgery and Physiology, University of Maryland School of Medicine, Baltimore, MD 6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Vascular and Inflammatory Disease, Departments of Surgery and Physiology, University of Maryland School of Medicine, Baltimore, MD 6","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047501668","display_name":"Karin Klingel","orcid":"https://orcid.org/0000-0003-0203-2498","observed_orcids":["https://orcid.org/0000-0003-0203-2498"]},"institutions":[{"id":"https://openalex.org/I4210094118","display_name":"Universit\u00e4tsklinikum T\u00fcbingen","ror":"https://ror.org/00pjgxh97","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094118"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Karin Klingel","raw_affiliation_strings":["Cardiopathology, Institute for Pathology and Neuropathology, University Hospital Tuebingen, Tuebingen, Germany 7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiopathology, Institute for Pathology and Neuropathology, University Hospital Tuebingen, Tuebingen, Germany 7","institution_ids":["https://openalex.org/I4210094118"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080557819","display_name":"Volker Brinkmann","orcid":"https://orcid.org/0000-0003-4735-3682","observed_orcids":["https://orcid.org/0000-0003-4735-3682"]},"institutions":[{"id":"https://openalex.org/I4210087223","display_name":"Max Planck Institute for Infection Biology","ror":"https://ror.org/0046gcs23","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210087223"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Volker Brinkmann","raw_affiliation_strings":["Department of Cellular Microbiology, Max Planck Institute for Infection Biology, Berlin, Germany 9","Microscopy Core Facility, Max Planck Institute for Infection Biology, Berlin, Germany 8"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Microbiology, Max Planck Institute for Infection Biology, Berlin, Germany 9","institution_ids":["https://openalex.org/I4210087223"]},{"raw_affiliation_string":"Microscopy Core Facility, Max Planck Institute for Infection Biology, Berlin, Germany 8","institution_ids":["https://openalex.org/I4210087223"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077107805","display_name":"Ulrike Abu Abed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087223","display_name":"Max Planck Institute for Infection Biology","ror":"https://ror.org/0046gcs23","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210087223"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ulrike Abu Abed","raw_affiliation_strings":["Department of Cellular Microbiology, Max Planck Institute for Infection Biology, Berlin, Germany 9","Microscopy Core Facility, Max Planck Institute for Infection Biology, Berlin, Germany 8"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Microbiology, Max Planck Institute for Infection Biology, Berlin, Germany 9","institution_ids":["https://openalex.org/I4210087223"]},{"raw_affiliation_string":"Microscopy Core Facility, Max Planck Institute for Infection Biology, Berlin, Germany 8","institution_ids":["https://openalex.org/I4210087223"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015449875","display_name":"Urs Eriksson","orcid":"https://orcid.org/0000-0003-1217-9696","observed_orcids":["https://orcid.org/0000-0003-1217-9696"]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I4210101371","display_name":"GZO Spital Wetzikon","ror":"https://ror.org/00pytyc14","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210101371"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Urs Eriksson","raw_affiliation_strings":["Cardioimmunology, Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland 10","Department of Medicine, Gesundheitsversorgung Z\u00fcrcher Oberland-Zurich Regional Health Center, Wetzikon, Switzerland 11"],"raw_orcid":"https://orcid.org/0000-0003-1217-9696","affiliations":[{"raw_affiliation_string":"Cardioimmunology, Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland 10","institution_ids":["https://openalex.org/I202697423"]},{"raw_affiliation_string":"Department of Medicine, Gesundheitsversorgung Z\u00fcrcher Oberland-Zurich Regional Health Center, Wetzikon, Switzerland 11","institution_ids":["https://openalex.org/I4210101371"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007093669","display_name":"Steffen Ma\u00dfberg","orcid":"https://orcid.org/0000-0001-7387-3986","observed_orcids":["https://orcid.org/0000-0001-7387-3986"]},"institutions":[{"id":"https://openalex.org/I3018771216","display_name":"LMU Klinikum","ror":"https://ror.org/02jet3w32","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4210127591","display_name":"German Centre for Cardiovascular Research","ror":"https://ror.org/031t5w623","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210127591","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Steffen Massberg","raw_affiliation_strings":["German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich, Germany 4","Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich, Germany 4","institution_ids":["https://openalex.org/I4210127591"]},{"raw_affiliation_string":"Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1","institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027883152","display_name":"Stefan Brunner","orcid":"https://orcid.org/0000-0001-6608-5279","observed_orcids":["https://orcid.org/0000-0001-6608-5279"]},"institutions":[{"id":"https://openalex.org/I3018771216","display_name":"LMU Klinikum","ror":"https://ror.org/02jet3w32","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Brunner","raw_affiliation_strings":["Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t, Ludwig-Maximilians-University Munich, Munich, Germany 1","institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079837507","display_name":"Barbara Walzog","orcid":"https://orcid.org/0000-0001-7729-6565","observed_orcids":["https://orcid.org/0000-0001-7729-6565"]},"institutions":[{"id":"https://openalex.org/I4405258122","display_name":"Institut f\u00fcr Chirurgische Forschung","ror":"https://ror.org/005506478","country_code":"DE","type":"facility","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405258122","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4405260491","display_name":"Institut f\u00fcr Kardiovaskul\u00e4re Physiologie und Pathophysiologie","ror":"https://ror.org/03tw5w184","country_code":"DE","type":"education","lineage":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Barbara Walzog","raw_affiliation_strings":["Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2"],"raw_orcid":"https://orcid.org/0000-0001-7729-6565","affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 3","institution_ids":["https://openalex.org/I4405260491","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Walter Brendel Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany 2","institution_ids":["https://openalex.org/I4405258122","https://openalex.org/I8204097"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5079837507","https://openalex.org/A5088259499"],"corresponding_institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I4210127591","https://openalex.org/I4405258122","https://openalex.org/I4405260491","https://openalex.org/I8204097"],"apc_list":null,"apc_paid":null,"fwci":10.1803,"has_fulltext":true,"cited_by_count":128,"citation_normalized_percentile":{"value":0.99086936,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"216","issue":"2","first_page":"350","last_page":"368"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11112","display_name":"Viral Infections and Immunology Research","score":0.5839999914169312,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11112","display_name":"Viral Infections and Immunology Research","score":0.5839999914169312,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.37450000643730164,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.00860000029206276,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/midkine","display_name":"midkine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/myocarditis","display_name":"myocarditis","score":0.9559999704360962},{"id":"https://openalex.org/keywords/neutrophil-extracellular-traps","display_name":"neutrophil extracellular traps","score":0.9369999766349792},{"id":"https://openalex.org/keywords/netosis","display_name":"NETosis","score":0.972000002861023},{"id":"https://openalex.org/keywords/neutrophil-trafficking","display_name":"neutrophil trafficking","score":0.8650000095367432},{"id":"https://openalex.org/keywords/cardiac-inflammation","display_name":"cardiac inflammation","score":0.878000020980835},{"id":"https://openalex.org/keywords/experimental-autoimmune-myocarditis","display_name":"experimental autoimmune myocarditis","score":0.9269999861717224},{"id":"https://openalex.org/keywords/lrp1","display_name":"LRP1","score":0.8830000162124634},{"id":"https://openalex.org/keywords/dilated-cardiomyopathy","display_name":"dilated cardiomyopathy","score":0.8930000066757202},{"id":"https://openalex.org/keywords/myocardial-fibrosis","display_name":"myocardial fibrosis","score":0.8040000200271606},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.49399998784065247}],"concepts":[{"id":"https://openalex.org/C2780875844","wikidata":"https://www.wikidata.org/wiki/Q186235","display_name":"Myocarditis","level":2,"score":0.85198974609375},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.7968037128448486},{"id":"https://openalex.org/C134897094","wikidata":"https://www.wikidata.org/wiki/Q7003141","display_name":"Neutrophil extracellular traps","level":3,"score":0.7873711585998535},{"id":"https://openalex.org/C139647698","wikidata":"https://www.wikidata.org/wiki/Q21111528","display_name":"LRP1","level":5,"score":0.7168413400650024},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.6985154151916504},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5705874562263489},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.528865396976471},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.508508563041687},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.46078741550445557},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.4188770651817322},{"id":"https://openalex.org/C158074577","wikidata":"https://www.wikidata.org/wiki/Q14907402","display_name":"Midkine","level":4,"score":0.41174066066741943},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3908161520957947},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.22356227040290833},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.185802161693573},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.10408404469490051},{"id":"https://openalex.org/C43554185","wikidata":"https://www.wikidata.org/wiki/Q425649","display_name":"LDL receptor","level":4,"score":0.09425586462020874},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.0},{"id":"https://openalex.org/C2775960820","wikidata":"https://www.wikidata.org/wiki/Q408378","display_name":"Growth factor","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000078792","descriptor_name":"Midkine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000078792","descriptor_name":"Midkine","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009205","descriptor_name":"Myocarditis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009205","descriptor_name":"Myocarditis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009205","descriptor_name":"Myocarditis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011973","descriptor_name":"Receptors, LDL","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011973","descriptor_name":"Receptors, LDL","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D025521","descriptor_name":"Tumor Suppressor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D025521","descriptor_name":"Tumor Suppressor Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D026503","descriptor_name":"Low Density Lipoprotein Receptor-Related Protein-1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D026503","descriptor_name":"Low Density Lipoprotein Receptor-Related Protein-1","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065206","descriptor_name":"Extracellular Traps","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D065206","descriptor_name":"Extracellular Traps","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":9,"locations":[{"id":"doi:10.1084/jem.20181102","doi":"https://doi.org/10.1084/jem.20181102","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.20181102","pdf_url":"https://rupress.org/jem/article-pdf/216/2/350/1171119/jem_20181102.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Medicine","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5625674","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6363424","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6363424","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6363424","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Med","raw_type":"Text"},{"id":"pmid:30647120","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30647120","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"Journal Article"},{"id":"pmh:oai:www.zora.uzh.ch:180352","doi":null,"is_oa":true,"landing_page_url":"https://www.zora.uzh.ch/id/eprint/180352/1/jem_20181102.pdf","pdf_url":"https://www.zora.uzh.ch/id/eprint/180352/1/jem_20181102.pdf","source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.mpg.de:item_3027633","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/21.11116/0000-0003-017B-2","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.mpg.de:item_3134556","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/21.11116/0000-0004-0510-4","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Experimental Medicine","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:www.zora.uzh.ch:20.500.14742/164615","doi":null,"is_oa":true,"landing_page_url":"https://www.zora.uzh.ch/handle/20.500.14742/164615","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Weckbach, L. T., Grabmaier, U., Uhl, A., Gess, S., Boehm, F., Zehrer, A., Pick, R., Salvermoser, M., Czermak, T., Pircher, J., Sorrelle, N., Migliorini, M., Strickland, D. K., Klingel, K., Brinkmann, V., Abu Abed, U., Eriksson, U., Massberg, S., Brunner, S., & Walzog, B. (2019). Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. Journal of Experimental Medicine, 216, 350\u2013368. https://doi.org/10.1084/jem.20181102","raw_type":"Journal Article"},{"id":"doi:10.5167/uzh-180352","doi":"https://doi.org/10.5167/uzh-180352","is_oa":true,"landing_page_url":"https://doi.org/10.5167/uzh-180352","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.1084/jem.20181102","doi":"https://doi.org/10.1084/jem.20181102","is_oa":true,"landing_page_url":"https://doi.org/10.1084/jem.20181102","pdf_url":"https://rupress.org/jem/article-pdf/216/2/350/1171119/jem_20181102.pdf","source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Experimental Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1803204493","display_name":null,"funder_award_id":"SFB 914","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G1861238208","display_name":null,"funder_award_id":"R35 HL125743","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2712587994","display_name":"Pleiotrophin Promotes a Pro-Tumor and Pro-Metastatic Phenotype - Resubmission - 1","funder_award_id":"F31CA196033","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4201645080","display_name":null,"funder_award_id":"project A02","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G8679467126","display_name":null,"funder_award_id":"DFG KL 595/2-3","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320312387","display_name":"Temple University","ror":"https://ror.org/00kx1jb78"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320326500","display_name":"Deutsche Gesellschaft f\u00fcr Kardiologie-Herz und Kreislaufforschung.","ror":"https://ror.org/02p22ad51"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2909293124.pdf","grobid_xml":"https://content.openalex.org/works/W2909293124.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W1550767186","https://openalex.org/W1604923955","https://openalex.org/W1627013070","https://openalex.org/W1925096404","https://openalex.org/W1965737875","https://openalex.org/W1967810755","https://openalex.org/W1974746267","https://openalex.org/W1978467398","https://openalex.org/W1981508107","https://openalex.org/W2001088595","https://openalex.org/W2018536993","https://openalex.org/W2018916027","https://openalex.org/W2027575580","https://openalex.org/W2035809865","https://openalex.org/W2064508795","https://openalex.org/W2082864993","https://openalex.org/W2084556092","https://openalex.org/W2089029717","https://openalex.org/W2093076255","https://openalex.org/W2104934425","https://openalex.org/W2107152905","https://openalex.org/W2113601375","https://openalex.org/W2113702448","https://openalex.org/W2117066685","https://openalex.org/W2127256767","https://openalex.org/W2128584846","https://openalex.org/W2132249471","https://openalex.org/W2134956904","https://openalex.org/W2140921081","https://openalex.org/W2145332276","https://openalex.org/W2146981926","https://openalex.org/W2147278149","https://openalex.org/W2160440202","https://openalex.org/W2160485534","https://openalex.org/W2160909954","https://openalex.org/W2161606388","https://openalex.org/W2267597338","https://openalex.org/W2342532453","https://openalex.org/W2555072060","https://openalex.org/W2562661149","https://openalex.org/W2570320605","https://openalex.org/W2570792206","https://openalex.org/W2593144838","https://openalex.org/W2611509799","https://openalex.org/W2621393405","https://openalex.org/W2626760894","https://openalex.org/W2886453020","https://openalex.org/W4312996562"],"related_works":["https://openalex.org/W2904175586","https://openalex.org/W2801042601","https://openalex.org/W2913626252","https://openalex.org/W4404190530","https://openalex.org/W6894100448","https://openalex.org/W7220905324","https://openalex.org/W7201973087","https://openalex.org/W4389953457","https://openalex.org/W4401083137","https://openalex.org/W4403817808"],"abstract_inverted_index":{"Heart":[0],"failure":[1],"due":[2],"to":[3,120],"dilated":[4],"cardiomyopathy":[5],"is":[6],"frequently":[7],"caused":[8],"by":[9],"myocarditis.":[10,37],"However,":[11],"the":[12,22,53,57,60,78,102,121,150],"pathogenesis":[13,122],"of":[14,24,32,39,47,56,80,123,152],"myocarditis":[15,45,124],"remains":[16],"incompletely":[17],"understood.":[18],"Here,":[19],"we":[20],"report":[21],"presence":[23],"neutrophil":[25],"extracellular":[26],"traps":[27],"(NETs)":[28],"in":[29,42,52,68,75],"cardiac":[30,127,153],"tissue":[31],"patients":[33],"and":[34,77,88,125,136],"mice":[35,48],"with":[36],"Inhibition":[38],"NET":[40,66,73,113],"formation":[41,67,74],"experimental":[43],"autoimmune":[44],"(EAM)":[46],"substantially":[49,118],"reduces":[50,86],"inflammation":[51],"acute":[54],"phase":[55],"disease.":[58],"Targeting":[59],"cytokine":[61],"midkine":[62],"(MK),":[63],"which":[64,132],"mediates":[65],"vitro,":[69],"not":[70],"only":[71],"attenuates":[72],"vivo":[76],"infiltration":[79],"polymorphonuclear":[81],"neutrophils":[82],"(PMNs)":[83],"but":[84],"also":[85],"fibrosis":[87],"preserves":[89],"systolic":[90],"function":[91],"during":[92],"EAM.":[93],"Low-density":[94],"lipoprotein":[95],"receptor-related":[96],"protein":[97],"1":[98],"(LRP1)":[99],"acts":[100],"as":[101,110,112,140,142],"functionally":[103],"relevant":[104],"receptor":[105],"for":[106,149],"MK-induced":[107],"PMN":[108,134],"recruitment":[109],"well":[111,141],"formation.":[114],"In":[115],"summary,":[116],"NETosis":[117],"contributes":[119],"drives":[126],"inflammation,":[128],"probably":[129],"via":[130],"MK,":[131],"promotes":[133],"trafficking":[135],"NETosis.":[137],"Thus,":[138],"MK":[139],"NETs":[143],"may":[144],"represent":[145],"novel":[146],"therapeutic":[147],"targets":[148],"treatment":[151],"inflammation.":[154]},"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":24},{"year":2024,"cited_by_count":19},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":18},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":10}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2019-01-25T00:00:00"}