{"id":"https://openalex.org/W2909130360","doi":"https://doi.org/10.1136/annrheumdis-2018-eular.6652","title":"AB0454 Biological therapies survival in adults and juvenile onset arthritis. data from biobadaguay registry","display_name":"AB0454 Biological therapies survival in adults and juvenile onset arthritis. data from biobadaguay registry","publication_year":2018,"publication_date":"2018-06-01","ids":{"openalex":"https://openalex.org/W2909130360","doi":"https://doi.org/10.1136/annrheumdis-2018-eular.6652","mag":"2909130360"},"language":"en","primary_location":{"id":"doi:10.1136/annrheumdis-2018-eular.6652","doi":"https://doi.org/10.1136/annrheumdis-2018-eular.6652","is_oa":true,"landing_page_url":"https://doi.org/10.1136/annrheumdis-2018-eular.6652","pdf_url":"https://ard.bmj.com/content/annrheumdis/77/Suppl_2/1389.1.full.pdf","source":{"id":"https://openalex.org/S25650217","display_name":"Annals of the Rheumatic Diseases","issn_l":"0003-4967","issn":["0003-4967","1468-2060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the Rheumatic Diseases","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ard.bmj.com/content/annrheumdis/77/Suppl_2/1389.1.full.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050789625","display_name":"M.G. Avila-Pedretti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166288","display_name":"IPS Central","ror":"https://ror.org/048b0cg51","country_code":"PY","type":"healthcare","lineage":["https://openalex.org/I4210166288"]}],"countries":["PY"],"is_corresponding":false,"raw_author_name":"M.G. Avila-Pedretti","raw_affiliation_strings":["Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social","institution_ids":["https://openalex.org/I4210166288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034226700","display_name":"Zoilo Morel","orcid":"https://orcid.org/0000-0001-6438-446X","observed_orcids":["https://orcid.org/0000-0001-6438-446X"]},"institutions":[{"id":"https://openalex.org/I4210166288","display_name":"IPS Central","ror":"https://ror.org/048b0cg51","country_code":"PY","type":"healthcare","lineage":["https://openalex.org/I4210166288"]}],"countries":["PY"],"is_corresponding":false,"raw_author_name":"Z. Morel","raw_affiliation_strings":["Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social","institution_ids":["https://openalex.org/I4210166288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053863751","display_name":"Natalia Cabrera","orcid":"https://orcid.org/0000-0001-9555-8645","observed_orcids":["https://orcid.org/0000-0001-9555-8645","https://orcid.org/0000-0003-3095-8482"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. Cabrera","raw_affiliation_strings":["Rheumatology, Sociedad Paraguaya de Reumatolog\u00eda, Asunci\u00f3n, Paraguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Sociedad Paraguaya de Reumatolog\u00eda, Asunci\u00f3n, Paraguay","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007766318","display_name":"Sonia Cabrera-Villalba","orcid":"https://orcid.org/0000-0001-6224-2679","observed_orcids":["https://orcid.org/0000-0001-6224-2679"]},"institutions":[{"id":"https://openalex.org/I4210166288","display_name":"IPS Central","ror":"https://ror.org/048b0cg51","country_code":"PY","type":"healthcare","lineage":["https://openalex.org/I4210166288"]}],"countries":["PY"],"is_corresponding":false,"raw_author_name":"S. Cabrera-Villalba","raw_affiliation_strings":["Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social","institution_ids":["https://openalex.org/I4210166288"]}]},{"author_position":"middle","author":{"id":null,"display_name":"I. Acosta Colman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166288","display_name":"IPS Central","ror":"https://ror.org/048b0cg51","country_code":"PY","type":"healthcare","lineage":["https://openalex.org/I4210166288"]}],"countries":["PY"],"is_corresponding":false,"raw_author_name":"I. Acosta Colman","raw_affiliation_strings":["Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social","institution_ids":["https://openalex.org/I4210166288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012719669","display_name":"Pedro Babak","orcid":"https://orcid.org/0009-0004-5234-5788","observed_orcids":["https://orcid.org/0009-0004-5234-5788"]},"institutions":[{"id":"https://openalex.org/I4210166288","display_name":"IPS Central","ror":"https://ror.org/048b0cg51","country_code":"PY","type":"healthcare","lineage":["https://openalex.org/I4210166288"]}],"countries":["PY"],"is_corresponding":false,"raw_author_name":"P. Babak","raw_affiliation_strings":["Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social","institution_ids":["https://openalex.org/I4210166288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072268449","display_name":"Patricia Melgarejo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166288","display_name":"IPS Central","ror":"https://ror.org/048b0cg51","country_code":"PY","type":"healthcare","lineage":["https://openalex.org/I4210166288"]}],"countries":["PY"],"is_corresponding":false,"raw_author_name":"P. Melgarejo","raw_affiliation_strings":["Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social","institution_ids":["https://openalex.org/I4210166288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014713645","display_name":"G. Elizaur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166288","display_name":"IPS Central","ror":"https://ror.org/048b0cg51","country_code":"PY","type":"healthcare","lineage":["https://openalex.org/I4210166288"]}],"countries":["PY"],"is_corresponding":false,"raw_author_name":"G. Elizaur","raw_affiliation_strings":["Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social","institution_ids":["https://openalex.org/I4210166288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112409217","display_name":"Marco Franco","orcid":"https://orcid.org/0000-0002-0071-4447","observed_orcids":["https://orcid.org/0000-0002-0071-4447"]},"institutions":[{"id":"https://openalex.org/I4210166288","display_name":"IPS Central","ror":"https://ror.org/048b0cg51","country_code":"PY","type":"healthcare","lineage":["https://openalex.org/I4210166288"]}],"countries":["PY"],"is_corresponding":false,"raw_author_name":"M. Franco","raw_affiliation_strings":["Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social","institution_ids":["https://openalex.org/I4210166288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032553679","display_name":"Pedro Delgadillo","orcid":"https://orcid.org/0000-0001-8588-3671","observed_orcids":["https://orcid.org/0000-0001-8588-3671"]},"institutions":[{"id":"https://openalex.org/I4210166288","display_name":"IPS Central","ror":"https://ror.org/048b0cg51","country_code":"PY","type":"healthcare","lineage":["https://openalex.org/I4210166288"]}],"countries":["PY"],"is_corresponding":false,"raw_author_name":"P. Delgadillo","raw_affiliation_strings":["Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social","institution_ids":["https://openalex.org/I4210166288"]}]},{"author_position":"middle","author":{"id":null,"display_name":"D. Cordovilla Montero","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Cordovilla Montero","raw_affiliation_strings":["Rheumatology, Insituto Nacional de Reumatolog\u00eda, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Insituto Nacional de Reumatolog\u00eda, Montevideo, Uruguay","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040603924","display_name":"Jhonatan Losanto","orcid":"https://orcid.org/0000-0002-8040-1562","observed_orcids":["https://orcid.org/0000-0002-8040-1562"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Losanto","raw_affiliation_strings":["Rheumatology, Hospital de Cl\u00ednicas, Asunci\u00f3n, Paraguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital de Cl\u00ednicas, Asunci\u00f3n, Paraguay","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064257214","display_name":"Lourdes Rom\u00e1n","orcid":"https://orcid.org/0009-0004-4994-6152","observed_orcids":["https://orcid.org/0009-0004-4994-6152"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L. Roman","raw_affiliation_strings":["Rheumatology, Hospital de Cl\u00ednicas, Asunci\u00f3n, Paraguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital de Cl\u00ednicas, Asunci\u00f3n, Paraguay","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"E. Paredes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166288","display_name":"IPS Central","ror":"https://ror.org/048b0cg51","country_code":"PY","type":"healthcare","lineage":["https://openalex.org/I4210166288"]}],"countries":["PY"],"is_corresponding":false,"raw_author_name":"E. Paredes","raw_affiliation_strings":["Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social","institution_ids":["https://openalex.org/I4210166288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057339688","display_name":"Julio Mazzoleni","orcid":"https://orcid.org/0009-0006-1189-5753","observed_orcids":["https://orcid.org/0009-0006-1189-5753"]},"institutions":[{"id":"https://openalex.org/I4210166288","display_name":"IPS Central","ror":"https://ror.org/048b0cg51","country_code":"PY","type":"healthcare","lineage":["https://openalex.org/I4210166288"]}],"countries":["PY"],"is_corresponding":false,"raw_author_name":"J. Mazzoleni","raw_affiliation_strings":["Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Hospital Central del Instituto de Previsi\u00f3n Social","institution_ids":["https://openalex.org/I4210166288"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071578780","display_name":"Paloma de Abreu","orcid":"https://orcid.org/0000-0002-2076-8258","observed_orcids":["https://orcid.org/0000-0002-2076-8258"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. de Abreu","raw_affiliation_strings":["Rheumatology, Sociedad Paraguaya de Reumatolog\u00eda, Asunci\u00f3n, Paraguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology, Sociedad Paraguaya de Reumatolog\u00eda, Asunci\u00f3n, Paraguay","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4870,"currency":"USD","value_usd":4870},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"77","issue":null,"first_page":"1389","last_page":"1389"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.8330000042915344,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.8330000042915344,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":0.13289999961853027,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods","score":0.014000000432133675,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/juvenile-idiopathic-arthritis","display_name":"juvenile idiopathic arthritis","score":0.8889999985694885},{"id":"https://openalex.org/keywords/etanercept","display_name":"etanercept","score":0.8669999837875366},{"id":"https://openalex.org/keywords/adalimumab","display_name":"adalimumab","score":1.0},{"id":"https://openalex.org/keywords/biologic-discontinuation","display_name":"biologic discontinuation","score":0.75},{"id":"https://openalex.org/keywords/treatment-efficacy-and-safety","display_name":"treatment efficacy and safety","score":0.5910000205039978},{"id":"https://openalex.org/keywords/first-line-biologic-therapy","display_name":"first-line biologic therapy","score":0.6349999904632568},{"id":"https://openalex.org/keywords/tocilizumab","display_name":"tocilizumab","score":0.6650000214576721},{"id":"https://openalex.org/keywords/infliximab","display_name":"infliximab","score":0.9810000061988831},{"id":"https://openalex.org/keywords/rituximab","display_name":"rituximab","score":0.9909999966621399}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9496546983718872},{"id":"https://openalex.org/C2777226972","wikidata":"https://www.wikidata.org/wiki/Q415343","display_name":"Etanercept","level":3,"score":0.9482936859130859},{"id":"https://openalex.org/C2780132546","wikidata":"https://www.wikidata.org/wiki/Q348260","display_name":"Adalimumab","level":3,"score":0.9215890765190125},{"id":"https://openalex.org/C2777178219","wikidata":"https://www.wikidata.org/wiki/Q425154","display_name":"Tocilizumab","level":3,"score":0.6537109017372131},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6331218481063843},{"id":"https://openalex.org/C2777138892","wikidata":"https://www.wikidata.org/wiki/Q415264","display_name":"Infliximab","level":3,"score":0.5979025363922119},{"id":"https://openalex.org/C2779605438","wikidata":"https://www.wikidata.org/wiki/Q2697833","display_name":"Abatacept","level":4,"score":0.5960440039634705},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.5686242580413818},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.5513123273849487},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.5483983755111694},{"id":"https://openalex.org/C10515644","wikidata":"https://www.wikidata.org/wiki/Q543310","display_name":"Survival analysis","level":2,"score":0.5354248285293579},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4883398711681366},{"id":"https://openalex.org/C66339696","wikidata":"https://www.wikidata.org/wiki/Q6089397","display_name":"Log-rank test","level":3,"score":0.4393059015274048},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.2765457034111023},{"id":"https://openalex.org/C2780653079","wikidata":"https://www.wikidata.org/wiki/Q412323","display_name":"Rituximab","level":3,"score":0.227748304605484},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.09454026818275452},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.06745386123657227},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1136/annrheumdis-2018-eular.6652","doi":"https://doi.org/10.1136/annrheumdis-2018-eular.6652","is_oa":true,"landing_page_url":"https://doi.org/10.1136/annrheumdis-2018-eular.6652","pdf_url":"https://ard.bmj.com/content/annrheumdis/77/Suppl_2/1389.1.full.pdf","source":{"id":"https://openalex.org/S25650217","display_name":"Annals of the Rheumatic Diseases","issn_l":"0003-4967","issn":["0003-4967","1468-2060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the Rheumatic Diseases","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1136/annrheumdis-2018-eular.6652","doi":"https://doi.org/10.1136/annrheumdis-2018-eular.6652","is_oa":true,"landing_page_url":"https://doi.org/10.1136/annrheumdis-2018-eular.6652","pdf_url":"https://ard.bmj.com/content/annrheumdis/77/Suppl_2/1389.1.full.pdf","source":{"id":"https://openalex.org/S25650217","display_name":"Annals of the Rheumatic Diseases","issn_l":"0003-4967","issn":["0003-4967","1468-2060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the Rheumatic Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2909130360.pdf","grobid_xml":"https://content.openalex.org/works/W2909130360.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4379794381","https://openalex.org/W2419094094","https://openalex.org/W2555685137","https://openalex.org/W3053679567","https://openalex.org/W2808295405","https://openalex.org/W2897242708","https://openalex.org/W2910485799","https://openalex.org/W4231404041","https://openalex.org/W3093850396","https://openalex.org/W2070341136"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2019-01-25T00:00:00"}