{"id":"https://openalex.org/W2908378017","doi":"https://doi.org/10.22146/farmaseutik.v13i2.40917","title":"Comparative Evaluation of Some Commercial Clopidogrel Tablets Available in Yemen","display_name":"Comparative Evaluation of Some Commercial Clopidogrel Tablets Available in Yemen","publication_year":2018,"publication_date":"2018-11-14","ids":{"openalex":"https://openalex.org/W2908378017","doi":"https://doi.org/10.22146/farmaseutik.v13i2.40917","mag":"2908378017"},"language":"en","primary_location":{"id":"doi:10.22146/farmaseutik.v13i2.40917","doi":"https://doi.org/10.22146/farmaseutik.v13i2.40917","is_oa":true,"landing_page_url":"https://doi.org/10.22146/farmaseutik.v13i2.40917","pdf_url":"https://jurnal.ugm.ac.id/majalahfarmaseutik/article/download/40917/22797","source":{"id":"https://openalex.org/S4210171264","display_name":"Majalah Farmaseutik","issn_l":"1410-590X","issn":["1410-590X","2614-0063"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310314959","host_organization_name":"Gadjah Mada University","host_organization_lineage":["https://openalex.org/P4310314959"],"host_organization_lineage_names":["Gadjah Mada University"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Majalah Farmaseutik","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://jurnal.ugm.ac.id/majalahfarmaseutik/article/download/40917/22797","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020080455","display_name":"Bassam Abduh Ali","orcid":"https://orcid.org/0000-0002-8335-874X","observed_orcids":["https://orcid.org/0000-0002-8335-874X"]},"institutions":[{"id":"https://openalex.org/I118692353","display_name":"University of Science and Technology","ror":"https://ror.org/05bj7sh33","country_code":"YE","type":"education","lineage":["https://openalex.org/I118692353"]}],"countries":["YE"],"is_corresponding":true,"raw_author_name":"Bassam Abduh Ali","raw_affiliation_strings":["Department of Pharmaceutics, Faculty of Pharmacy, University of Science and Technology, Taiz Branch, Yemen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Faculty of Pharmacy, University of Science and Technology, Taiz Branch, Yemen","institution_ids":["https://openalex.org/I118692353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061436094","display_name":"Mohammed Gameel Al-Haddad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118692353","display_name":"University of Science and Technology","ror":"https://ror.org/05bj7sh33","country_code":"YE","type":"education","lineage":["https://openalex.org/I118692353"]},{"id":"https://openalex.org/I4405264759","display_name":"University of Science and Technology \u2013 Hodeidah Branch","ror":"https://ror.org/02wqnqt10","country_code":"YE","type":"education","lineage":["https://openalex.org/I4387153165","https://openalex.org/I4405264759"]}],"countries":["YE"],"is_corresponding":false,"raw_author_name":"Mohammed Gameel Al-haddad","raw_affiliation_strings":["Department of Pharmaceutics, Faculty of Pharmacy, University of Science and Technology, Hodaidah Branch, Yemen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Faculty of Pharmacy, University of Science and Technology, Hodaidah Branch, Yemen","institution_ids":["https://openalex.org/I118692353","https://openalex.org/I4405264759"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048845460","display_name":"Abdullah Ahmed Areqi","orcid":"https://orcid.org/0000-0003-3293-5006","observed_orcids":["https://orcid.org/0000-0003-3293-5006"]},"institutions":[{"id":"https://openalex.org/I118692353","display_name":"University of Science and Technology","ror":"https://ror.org/05bj7sh33","country_code":"YE","type":"education","lineage":["https://openalex.org/I118692353"]},{"id":"https://openalex.org/I4405264759","display_name":"University of Science and Technology \u2013 Hodeidah Branch","ror":"https://ror.org/02wqnqt10","country_code":"YE","type":"education","lineage":["https://openalex.org/I4387153165","https://openalex.org/I4405264759"]}],"countries":["YE"],"is_corresponding":false,"raw_author_name":"Abdullah Ahmed Areqi","raw_affiliation_strings":["Department of Pharmacology, Faculty of Pharmacy, University of Science and Technology, Hodiadah, Yemen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Faculty of Pharmacy, University of Science and Technology, Hodiadah, Yemen","institution_ids":["https://openalex.org/I118692353","https://openalex.org/I4405264759"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5020080455"],"corresponding_institution_ids":["https://openalex.org/I118692353"],"apc_list":null,"apc_paid":null,"fwci":0.2333,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.57849203,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"13","issue":"2","first_page":"79","last_page":"79"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12878","display_name":"Pharmaceutical Quality and Counterfeiting","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12878","display_name":"Pharmaceutical Quality and Counterfeiting","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.03150000050663948,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11792","display_name":"Pharmaceutical Economics and Policy","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clopidogrel","display_name":"clopidogrel","score":0.9390000104904175},{"id":"https://openalex.org/keywords/tablet-quality-control","display_name":"tablet quality control","score":0.5849999785423279},{"id":"https://openalex.org/keywords/weight-variation","display_name":"weight variation","score":0.8309999704360962},{"id":"https://openalex.org/keywords/hardness","display_name":"hardness","score":0.6740000247955322},{"id":"https://openalex.org/keywords/friability","display_name":"friability","score":0.9110000133514404},{"id":"https://openalex.org/keywords/disintegration-time","display_name":"disintegration time","score":0.8859999775886536},{"id":"https://openalex.org/keywords/in-vitro-drug-release","display_name":"in vitro drug release","score":0.8309999704360962},{"id":"https://openalex.org/keywords/potency-assay","display_name":"potency assay","score":0.6650000214576721},{"id":"https://openalex.org/keywords/antithrombotic-agents","display_name":"antithrombotic agents","score":0.7080000042915344}],"concepts":[{"id":"https://openalex.org/C191168616","wikidata":"https://www.wikidata.org/wiki/Q5503337","display_name":"Friability","level":4,"score":0.9413308501243591},{"id":"https://openalex.org/C2777849778","wikidata":"https://www.wikidata.org/wiki/Q410237","display_name":"Clopidogrel","level":3,"score":0.755242109298706},{"id":"https://openalex.org/C57992300","wikidata":"https://www.wikidata.org/wiki/Q2066956","display_name":"Potency","level":3,"score":0.6202359795570374},{"id":"https://openalex.org/C14029885","wikidata":"https://www.wikidata.org/wiki/Q5282807","display_name":"Dissolution testing","level":4,"score":0.5923007130622864},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4410012364387512},{"id":"https://openalex.org/C2777594072","wikidata":"https://www.wikidata.org/wiki/Q117247","display_name":"Pharmacopoeia","level":3,"score":0.44046998023986816},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4054167866706848},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.38693514466285706},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.32013702392578125},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1876620352268219},{"id":"https://openalex.org/C2777628954","wikidata":"https://www.wikidata.org/wiki/Q18216","display_name":"Aspirin","level":2,"score":0.17917421460151672},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.08314356207847595},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.06921115517616272},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C2781430271","wikidata":"https://www.wikidata.org/wiki/Q278760","display_name":"Biopharmaceutics Classification System","level":3,"score":0.0},{"id":"https://openalex.org/C201253974","wikidata":"https://www.wikidata.org/wiki/Q1330121","display_name":"First pass effect","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.22146/farmaseutik.v13i2.40917","doi":"https://doi.org/10.22146/farmaseutik.v13i2.40917","is_oa":true,"landing_page_url":"https://doi.org/10.22146/farmaseutik.v13i2.40917","pdf_url":"https://jurnal.ugm.ac.id/majalahfarmaseutik/article/download/40917/22797","source":{"id":"https://openalex.org/S4210171264","display_name":"Majalah Farmaseutik","issn_l":"1410-590X","issn":["1410-590X","2614-0063"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310314959","host_organization_name":"Gadjah Mada University","host_organization_lineage":["https://openalex.org/P4310314959"],"host_organization_lineage_names":["Gadjah Mada University"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Majalah Farmaseutik","raw_type":"journal-article"},{"id":"pmh:oai:journal.ugm.ac.id:article/40917","doi":null,"is_oa":true,"landing_page_url":"https://journal.ugm.ac.id/majalahfarmaseutik/article/view/40917","pdf_url":"https://journal.ugm.ac.id/majalahfarmaseutik/article/download/40917/22797","source":{"id":"https://openalex.org/S4210171264","display_name":"Majalah Farmaseutik","issn_l":"1410-590X","issn":["1410-590X","2614-0063"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310314959","host_organization_name":"Gadjah Mada University","host_organization_lineage":["https://openalex.org/P4310314959"],"host_organization_lineage_names":["Gadjah Mada University"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"1410-590X","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.22146/farmaseutik.v13i2.40917","doi":"https://doi.org/10.22146/farmaseutik.v13i2.40917","is_oa":true,"landing_page_url":"https://doi.org/10.22146/farmaseutik.v13i2.40917","pdf_url":"https://jurnal.ugm.ac.id/majalahfarmaseutik/article/download/40917/22797","source":{"id":"https://openalex.org/S4210171264","display_name":"Majalah Farmaseutik","issn_l":"1410-590X","issn":["1410-590X","2614-0063"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310314959","host_organization_name":"Gadjah Mada University","host_organization_lineage":["https://openalex.org/P4310314959"],"host_organization_lineage_names":["Gadjah Mada University"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Majalah Farmaseutik","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2908378017.pdf","grobid_xml":"https://content.openalex.org/works/W2908378017.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4297936494","https://openalex.org/W2897627937","https://openalex.org/W3182597251","https://openalex.org/W4206112348","https://openalex.org/W7156223969","https://openalex.org/W4293507291","https://openalex.org/W4417497044","https://openalex.org/W2392387581","https://openalex.org/W2348267888","https://openalex.org/W7216292278"],"abstract_inverted_index":{"Clopidogrel":[0,47,58,197],"is":[1,31],"a":[2],"medication":[3],"to":[4,34,39,86,104],"reduce":[5],"the":[6,18,51,90,106,115,118,182,188,202,207],"risk":[7],"of":[8,15,44,57,120,130,152,169,176],"heart":[9],"disease":[10],"and":[11,21,81,109,137,204],"taken":[12],"orally.":[13],"Quality":[14],"drug":[16,170],"characterizes":[17],"production":[19],"process":[20],"every":[22],"phamaceutical":[23],"company":[24],"strives":[25],"for":[26],"it":[27,30],"but":[28],"often":[29],"very":[32],"difficult":[33],"achieve.":[35],"This":[36,191],"study":[37,192],"was":[38,102,133,180],"investigate":[40],"quality":[41,74,203],"control":[42],"parameters":[43,75],"some":[45],"marketed":[46,55],"tablets.":[48],"To":[49],"assess":[50],"quality,":[52],"eight":[53],"different":[54,68],"brands":[56,116,132,156,179,185],"75":[59],"mg":[60],"tablets":[61,198],"available":[62],"in":[63,70,141,171,199],"Yemeni":[64],"market":[65],"collected":[66],"from":[67],"pharmacies":[69],"Hodeida":[71],"city.":[72],"Different":[73],"like":[76],"weight":[77,126],"variation,":[78],"hardness,":[79],"thickness":[80],"friability":[82],"were":[83,97],"determined":[84],"according":[85],"established":[87],"protocols.":[88],"Then":[89],"in-vitro":[91],"dissolution":[92,153,161],"test,":[93],"potency,":[94],"disintegration":[95,142],"time":[96,162],"also":[98,186],"carried":[99],"out.":[100],"UV-spectrophotometer":[101],"used":[103],"determine":[105],"percentage":[107],"released":[108,165],"assay":[110],"at":[111],"218":[112],"nm.":[113],"All":[114,184],"comply":[117,205],"requirements":[119],"Pharmacopoeia":[121],"as":[122,144,163],"they":[123,145,164],"showed":[124,159],"acceptable":[125,160],"variation":[127],"range.":[128,183],"Friability":[129],"all":[131,155],"less":[134],"than":[135,167],"1%":[136],"no":[138],"significant":[139],"differences":[140],"times":[143],"disintegrated":[146],"within":[147,181],"15":[148],"minutes.":[149],"In":[150],"case":[151],"profile,":[154],"except":[157],"C6":[158],"more":[166],"60%":[168],"45":[172],"minute.":[173],"The":[174],"hardness":[175],"only":[177],"two":[178],"meet":[187],"potency":[189],"specifications.":[190,209],"suggested":[193],"that":[194],"most":[195],"commercially":[196],"Yemen":[200],"maintain":[201],"with":[206],"pharmacopeia":[208]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-01-11T00:00:00"}