{"id":"https://openalex.org/W2908289332","doi":null,"title":"Efficacy and Safety of the PCSK9 Inhibitor Evolocumab (AMG 145) in Patients with Type 2 Diabetes","display_name":"Efficacy and Safety of the PCSK9 Inhibitor Evolocumab (AMG 145) in Patients with Type 2 Diabetes","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2908289332","mag":"2908289332"},"language":"en","primary_location":{"id":"mag:2908289332","doi":null,"is_oa":false,"landing_page_url":"https://www.cardioscience.ox.ac.uk/publications/882450","pdf_url":null,"source":{"id":"https://openalex.org/S129060628","display_name":"Diabetes","issn_l":"0012-1797","issn":["0012-1797","1939-327X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Diabetes","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078498803","display_name":"Naveed A. Sattar","orcid":"https://orcid.org/0000-0002-1604-2593","observed_orcids":["https://orcid.org/0000-0002-1604-2593"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Naveed Sattar","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1604-2593","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004271735","display_name":"C. Stephen Djedjos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Stephen Djedjos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089418361","display_name":"Jennifer G. Robinson","orcid":"https://orcid.org/0000-0002-4432-4352","observed_orcids":["https://orcid.org/0000-0002-4432-4352"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Robinson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039985378","display_name":"David Preiss","orcid":"https://orcid.org/0000-0003-3139-1836","observed_orcids":["https://orcid.org/0000-0003-3139-1836"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Preiss","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3139-1836","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Mary Elliott","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mary Elliott","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025538949","display_name":"Ransi M. Somaratne","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ransi Somaratne","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086317157","display_name":"Scott M. Wasserman","orcid":"https://orcid.org/0000-0003-0634-6021","observed_orcids":["https://orcid.org/0000-0003-0634-6021"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Scott M. Wasserman","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0634-6021","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5044425699","display_name":"Frederick Johan Raal","orcid":"https://orcid.org/0000-0002-9170-7938","observed_orcids":["https://orcid.org/0000-0002-9170-7938"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Frederick J. Raal","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9170-7938","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9078,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.79227874,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"64","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/evolocumab","display_name":"evolocumab","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pcsk9-inhibitors","display_name":"PCSK9 inhibitors","score":0.9769999980926514},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9950000047683716},{"id":"https://openalex.org/keywords/ldl-cholesterol-lowering","display_name":"LDL cholesterol lowering","score":0.8299999833106995},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.7900000214576721},{"id":"https://openalex.org/keywords/drug-efficacy","display_name":"drug efficacy","score":0.5680000185966492},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.9890000224113464}],"concepts":[{"id":"https://openalex.org/C2778114629","wikidata":"https://www.wikidata.org/wiki/Q15623825","display_name":"Evolocumab","level":5,"score":0.8681901693344116},{"id":"https://openalex.org/C2780948078","wikidata":"https://www.wikidata.org/wiki/Q21130010","display_name":"PCSK9","level":5,"score":0.800565242767334},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.7013362646102905},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6254682540893555},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5035075545310974},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.48398756980895996},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4631030261516571},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.38518810272216797},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.1624167561531067},{"id":"https://openalex.org/C2994423189","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Total cholesterol","level":3,"score":0.06929334998130798},{"id":"https://openalex.org/C43554185","wikidata":"https://www.wikidata.org/wiki/Q425649","display_name":"LDL receptor","level":4,"score":0.06511873006820679},{"id":"https://openalex.org/C2780745583","wikidata":"https://www.wikidata.org/wiki/Q1316030","display_name":"Apolipoprotein A1","level":4,"score":0.0},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2908289332","doi":null,"is_oa":false,"landing_page_url":"https://www.cardioscience.ox.ac.uk/publications/882450","pdf_url":null,"source":{"id":"https://openalex.org/S129060628","display_name":"Diabetes","issn_l":"0012-1797","issn":["0012-1797","1939-327X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Diabetes","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2490170668","https://openalex.org/W2780722543","https://openalex.org/W2266600614","https://openalex.org/W2070668396","https://openalex.org/W2477477042","https://openalex.org/W3120519358","https://openalex.org/W2254231529","https://openalex.org/W1993334958","https://openalex.org/W7073775669","https://openalex.org/W2467885405"],"abstract_inverted_index":null,"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2019-01-11T00:00:00"}