{"id":"https://openalex.org/W2906817193","doi":"https://doi.org/10.1016/j.jddst.2018.12.027","title":"Bioavailability enhanced clopidogrel -loaded solid SNEDDS: Development and in-vitro/in-vivo characterization","display_name":"Bioavailability enhanced clopidogrel -loaded solid SNEDDS: Development and in-vitro/in-vivo characterization","publication_year":2018,"publication_date":"2018-12-28","ids":{"openalex":"https://openalex.org/W2906817193","doi":"https://doi.org/10.1016/j.jddst.2018.12.027","mag":"2906817193"},"language":"en","primary_location":{"id":"doi:10.1016/j.jddst.2018.12.027","doi":"https://doi.org/10.1016/j.jddst.2018.12.027","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jddst.2018.12.027","pdf_url":null,"source":{"id":"https://openalex.org/S97205441","display_name":"Journal of Drug Delivery Science and Technology","issn_l":"1773-2247","issn":["1773-2247","2588-8943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Delivery Science and Technology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020736911","display_name":"Eman Abdelhakeem","orcid":"https://orcid.org/0000-0001-6077-3441","observed_orcids":["https://orcid.org/0000-0001-6077-3441"]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Eman Abd-Elhakeem","raw_affiliation_strings":["Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt"],"raw_orcid":"https://orcid.org/0000-0001-6077-3441","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt","institution_ids":["https://openalex.org/I145487455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025581601","display_name":"Mahmoud H. M. Teaima","orcid":"https://orcid.org/0000-0002-7565-301X","observed_orcids":["https://orcid.org/0000-0002-7565-301X"]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mahmoud HM. Teaima","raw_affiliation_strings":["Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt","institution_ids":["https://openalex.org/I145487455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015617681","display_name":"Ghada Ahmed Abdelbary","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Ghada A. Abdelbary","raw_affiliation_strings":["Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt","institution_ids":["https://openalex.org/I145487455"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5104116965","display_name":"Galal Mohamed El-Mahrouk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Galal M. El Mahrouk","raw_affiliation_strings":["Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt","institution_ids":["https://openalex.org/I145487455"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5015617681"],"corresponding_institution_ids":["https://openalex.org/I145487455"],"apc_list":{"value":3810,"currency":"USD","value_usd":3810},"apc_paid":null,"fwci":2.1039,"has_fulltext":false,"cited_by_count":61,"citation_normalized_percentile":{"value":0.83852573,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"49","issue":null,"first_page":"603","last_page":"614"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clopidogrel","display_name":"clopidogrel","score":0.9959999918937683},{"id":"https://openalex.org/keywords/self-nanoemulsifying-drug-delivery-system","display_name":"self-nanoemulsifying drug delivery system","score":0.9150000214576721},{"id":"https://openalex.org/keywords/oral-bioavailability-enhancement","display_name":"oral bioavailability enhancement","score":0.9559999704360962},{"id":"https://openalex.org/keywords/pseudo-ternary-phase-diagram","display_name":"pseudo-ternary phase diagram","score":0.8259999752044678},{"id":"https://openalex.org/keywords/transcutol-hp","display_name":"Transcutol HP","score":0.972000002861023},{"id":"https://openalex.org/keywords/capryol-90","display_name":"Capryol 90","score":0.9580000042915344},{"id":"https://openalex.org/keywords/globule-size","display_name":"globule size","score":0.703000009059906},{"id":"https://openalex.org/keywords/in-vitro-drug-release","display_name":"in vitro drug release","score":0.8309999704360962},{"id":"https://openalex.org/keywords/liver-metabolism","display_name":"hepatic metabolism","score":0.7329999804496765},{"id":"https://openalex.org/keywords/antiplatelet-drugs","display_name":"antiplatelet agents","score":0.7739999890327454}],"concepts":[{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.9603438377380371},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6223087310791016},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5755344033241272},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.519934356212616},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.47747373580932617},{"id":"https://openalex.org/C11432220","wikidata":"https://www.wikidata.org/wiki/Q1975334","display_name":"Dispersity","level":2,"score":0.46605974435806274},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.45761838555336},{"id":"https://openalex.org/C39519442","wikidata":"https://www.wikidata.org/wiki/Q904893","display_name":"Differential scanning calorimetry","level":2,"score":0.44796067476272583},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.44211190938949585},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.35576725006103516},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.10313570499420166},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1031053364276886},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jddst.2018.12.027","doi":"https://doi.org/10.1016/j.jddst.2018.12.027","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jddst.2018.12.027","pdf_url":null,"source":{"id":"https://openalex.org/S97205441","display_name":"Journal of Drug Delivery Science and Technology","issn_l":"1773-2247","issn":["1773-2247","2588-8943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Delivery Science and Technology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W1482561213","https://openalex.org/W1518223697","https://openalex.org/W1522125643","https://openalex.org/W1781486978","https://openalex.org/W1831847674","https://openalex.org/W1874727364","https://openalex.org/W1952796400","https://openalex.org/W1964549091","https://openalex.org/W1964811770","https://openalex.org/W1967773336","https://openalex.org/W1973913628","https://openalex.org/W1975404927","https://openalex.org/W1981081691","https://openalex.org/W1981493239","https://openalex.org/W1982070112","https://openalex.org/W1988249648","https://openalex.org/W1989426152","https://openalex.org/W2000820845","https://openalex.org/W2014688741","https://openalex.org/W2020487511","https://openalex.org/W2021036563","https://openalex.org/W2022258204","https://openalex.org/W2025763171","https://openalex.org/W2033285477","https://openalex.org/W2045015004","https://openalex.org/W2048948729","https://openalex.org/W2059740626","https://openalex.org/W2062156882","https://openalex.org/W2069060532","https://openalex.org/W2069295596","https://openalex.org/W2077890234","https://openalex.org/W2082382445","https://openalex.org/W2082799017","https://openalex.org/W2087335987","https://openalex.org/W2087908293","https://openalex.org/W2088142318","https://openalex.org/W2088684015","https://openalex.org/W2090485171","https://openalex.org/W2094735667","https://openalex.org/W2095204097","https://openalex.org/W2132917402","https://openalex.org/W2138682263","https://openalex.org/W2155197175","https://openalex.org/W2166547808","https://openalex.org/W2166666054","https://openalex.org/W2166775964","https://openalex.org/W2312909794","https://openalex.org/W2334074361","https://openalex.org/W2337174722","https://openalex.org/W2405379010","https://openalex.org/W2461190436","https://openalex.org/W2486388873","https://openalex.org/W2499143978","https://openalex.org/W2517199481","https://openalex.org/W2555572261","https://openalex.org/W2595931317","https://openalex.org/W2606431397","https://openalex.org/W2748626646","https://openalex.org/W2753432471","https://openalex.org/W2793794806","https://openalex.org/W2993394468","https://openalex.org/W4230238558","https://openalex.org/W4236129962","https://openalex.org/W4242516997","https://openalex.org/W4411657021","https://openalex.org/W6638339851"],"related_works":["https://openalex.org/W2965546521","https://openalex.org/W3193695963","https://openalex.org/W3146222602","https://openalex.org/W4285702985","https://openalex.org/W2068886062","https://openalex.org/W7220382986","https://openalex.org/W2033730332","https://openalex.org/W2076216132","https://openalex.org/W4407290511","https://openalex.org/W1923157591"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-01-11T00:00:00"}