{"id":"https://openalex.org/W2906722309","doi":null,"title":"Doublecortin-like kinase 1 as a novel drug target and biomarker in gastrointestinal and renal cancers","display_name":"Doublecortin-like kinase 1 as a novel drug target and biomarker in gastrointestinal and renal cancers","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2906722309","mag":"2906722309"},"language":"en","primary_location":{"id":"mag:2906722309","doi":null,"is_oa":false,"landing_page_url":"https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.749277","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009546120","display_name":"Nathaniel Weygant","orcid":"https://orcid.org/0000-0001-7861-6532","observed_orcids":["https://orcid.org/0000-0001-7861-6532"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Nathaniel Weygant","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7861-6532","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5009546120"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13779","display_name":"Cancer Mechanisms and Therapy","score":0.9082000255584717,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13779","display_name":"Cancer Mechanisms and Therapy","score":0.9082000255584717,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.03220000118017197,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dclk1","display_name":"DCLK1","score":0.9800000190734863},{"id":"https://openalex.org/keywords/gastrointestinal-cancer","display_name":"gastrointestinal cancer","score":0.6259999871253967},{"id":"https://openalex.org/keywords/kidney-cancer","display_name":"kidney cancer","score":0.984000027179718},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.9599999785423279},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.9670000076293945}],"concepts":[{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.6693131327629089},{"id":"https://openalex.org/C2781461022","wikidata":"https://www.wikidata.org/wiki/Q14912973","display_name":"Doublecortin","level":4,"score":0.6658079028129578},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5484264492988586},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5020391941070557},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4681553840637207},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3999931514263153},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34807729721069336},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33063897490501404},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2766590714454651},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09464818239212036},{"id":"https://openalex.org/C2776464000","wikidata":"https://www.wikidata.org/wiki/Q545787","display_name":"Dentate gyrus","level":3,"score":0.0},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2906722309","doi":null,"is_oa":false,"landing_page_url":"https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.749277","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":177,"referenced_works":["https://openalex.org/W136121639","https://openalex.org/W747812284","https://openalex.org/W1122276577","https://openalex.org/W1498201286","https://openalex.org/W1511804816","https://openalex.org/W1552842941","https://openalex.org/W1582276041","https://openalex.org/W1719320996","https://openalex.org/W1735537822","https://openalex.org/W1741548448","https://openalex.org/W1797689943","https://openalex.org/W1805581579","https://openalex.org/W1842991947","https://openalex.org/W1943370337","https://openalex.org/W1963965802","https://openalex.org/W1964405387","https://openalex.org/W1964847767","https://openalex.org/W1968933400","https://openalex.org/W1971141723","https://openalex.org/W1973596384","https://openalex.org/W1980507090","https://openalex.org/W1983549526","https://openalex.org/W1983991097","https://openalex.org/W1985425984","https://openalex.org/W1985727076","https://openalex.org/W1987050674","https://openalex.org/W1987979188","https://openalex.org/W1989952421","https://openalex.org/W1991541000","https://openalex.org/W1992682395","https://openalex.org/W1994216131","https://openalex.org/W1996944921","https://openalex.org/W1996962547","https://openalex.org/W1997031688","https://openalex.org/W2000005023","https://openalex.org/W2005057422","https://openalex.org/W2007606010","https://openalex.org/W2009886857","https://openalex.org/W2011789333","https://openalex.org/W2012034410","https://openalex.org/W2014691022","https://openalex.org/W2014699342","https://openalex.org/W2018348035","https://openalex.org/W2019214567","https://openalex.org/W2023427658","https://openalex.org/W2025659071","https://openalex.org/W2027044610","https://openalex.org/W2027922031","https://openalex.org/W2032347026","https://openalex.org/W2034145329","https://openalex.org/W2035272743","https://openalex.org/W2036844438","https://openalex.org/W2041596915","https://openalex.org/W2051244361","https://openalex.org/W2051976149","https://openalex.org/W2053352622","https://openalex.org/W2054609442","https://openalex.org/W2056930212","https://openalex.org/W2059585567","https://openalex.org/W2060587243","https://openalex.org/W2062759109","https://openalex.org/W2066362124","https://openalex.org/W2068769869","https://openalex.org/W2070486022","https://openalex.org/W2073842881","https://openalex.org/W2079830672","https://openalex.org/W2079968038","https://openalex.org/W2080281313","https://openalex.org/W2084074138","https://openalex.org/W2085403697","https://openalex.org/W2086875512","https://openalex.org/W2090150239","https://openalex.org/W2090279335","https://openalex.org/W2090562908","https://openalex.org/W2090982381","https://openalex.org/W2092893236","https://openalex.org/W2093899115","https://openalex.org/W2094831008","https://openalex.org/W2095692554","https://openalex.org/W2097259163","https://openalex.org/W2100540583","https://openalex.org/W2100901040","https://openalex.org/W2102032782","https://openalex.org/W2103288730","https://openalex.org/W2104437608","https://openalex.org/W2107941234","https://openalex.org/W2109661968","https://openalex.org/W2110937119","https://openalex.org/W2111867681","https://openalex.org/W2112318168","https://openalex.org/W2112911107","https://openalex.org/W2114496204","https://openalex.org/W2116010339","https://openalex.org/W2117692326","https://openalex.org/W2118090796","https://openalex.org/W2118107482","https://openalex.org/W2122737206","https://openalex.org/W2123216084","https://openalex.org/W2124681346","https://openalex.org/W2124715710","https://openalex.org/W2125293263","https://openalex.org/W2125486087","https://openalex.org/W2126547130","https://openalex.org/W2127554019","https://openalex.org/W2132387165","https://openalex.org/W2132780101","https://openalex.org/W2133082302","https://openalex.org/W2133094954","https://openalex.org/W2133917785","https://openalex.org/W2134197481","https://openalex.org/W2136498843","https://openalex.org/W2140909375","https://openalex.org/W2142286131","https://openalex.org/W2142421871","https://openalex.org/W2147807172","https://openalex.org/W2153724086","https://openalex.org/W2158403848","https://openalex.org/W2159291539","https://openalex.org/W2160562062","https://openalex.org/W2160888498","https://openalex.org/W2164899193","https://openalex.org/W2165153403","https://openalex.org/W2169669025","https://openalex.org/W2180481128","https://openalex.org/W2184789538","https://openalex.org/W2191813810","https://openalex.org/W2222086386","https://openalex.org/W2227866773","https://openalex.org/W2233158352","https://openalex.org/W2262414037","https://openalex.org/W2275877493","https://openalex.org/W2278768857","https://openalex.org/W2284015160","https://openalex.org/W2289015321","https://openalex.org/W2298868531","https://openalex.org/W2328695752","https://openalex.org/W2335012284","https://openalex.org/W2340024299","https://openalex.org/W2344302368","https://openalex.org/W2409595494","https://openalex.org/W2412290778","https://openalex.org/W2413289852","https://openalex.org/W2417336695","https://openalex.org/W2483248188","https://openalex.org/W2493405297","https://openalex.org/W2501125746","https://openalex.org/W2510429262","https://openalex.org/W2514305496","https://openalex.org/W2516688562","https://openalex.org/W2528656882","https://openalex.org/W2552238037","https://openalex.org/W2554987853","https://openalex.org/W2558932596","https://openalex.org/W2570401594","https://openalex.org/W2575543752","https://openalex.org/W2581279204","https://openalex.org/W2582686270","https://openalex.org/W2585723656","https://openalex.org/W2590947655","https://openalex.org/W2591975886","https://openalex.org/W2593932179","https://openalex.org/W2596077424","https://openalex.org/W2601908252","https://openalex.org/W2603666401","https://openalex.org/W2604024577","https://openalex.org/W2606001457","https://openalex.org/W2606691626","https://openalex.org/W2619969047","https://openalex.org/W2750333573","https://openalex.org/W2751273694","https://openalex.org/W2752775557","https://openalex.org/W2755683918","https://openalex.org/W2767423581","https://openalex.org/W2768600953","https://openalex.org/W2770880161","https://openalex.org/W2917738795","https://openalex.org/W3134530972"],"related_works":["https://openalex.org/W1505894369","https://openalex.org/W4400775276","https://openalex.org/W4296538634","https://openalex.org/W3014346297","https://openalex.org/W2479789651","https://openalex.org/W6920903009","https://openalex.org/W3178397585","https://openalex.org/W4392188378","https://openalex.org/W3210937792","https://openalex.org/W7095117628"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2019-01-11T00:00:00"}