{"id":"https://openalex.org/W2906659040","doi":"https://doi.org/10.65137/lmj.v4i1.74","title":"Comparison between the efficacy and tolerability of On Demand Sildenafil citrate and Tadalafil in Treatment of Erectile Dysfunction in Type 2 Diabetic Patients","display_name":"Comparison between the efficacy and tolerability of On Demand Sildenafil citrate and Tadalafil in Treatment of Erectile Dysfunction in Type 2 Diabetic Patients","publication_year":2018,"publication_date":"2018-06-26","ids":{"openalex":"https://openalex.org/W2906659040","doi":"https://doi.org/10.65137/lmj.v4i1.74","mag":"2906659040"},"language":"en","primary_location":{"id":"doi:10.65137/lmj.v4i1.74","doi":"https://doi.org/10.65137/lmj.v4i1.74","is_oa":true,"landing_page_url":"https://doi.org/10.65137/lmj.v4i1.74","pdf_url":"https://lebmedj.elmergib.edu.ly/index.php/LMJ/article/download/74/31","source":{"id":"https://openalex.org/S5407053242","display_name":"Lebda Medical Journal","issn_l":"2520-0941","issn":["2520-0941","2520-095X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lebda Medical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://lebmedj.elmergib.edu.ly/index.php/LMJ/article/download/74/31","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053365766","display_name":"Salem Hasn Abukres","orcid":"https://orcid.org/0009-0007-5598-7112","observed_orcids":["https://orcid.org/0009-0007-5598-7112"]},"institutions":[{"id":"https://openalex.org/I4210148074","display_name":"University Elmergib","ror":"https://ror.org/056mwwj30","country_code":"LY","type":"education","lineage":["https://openalex.org/I4210148074"]}],"countries":["LY"],"is_corresponding":false,"raw_author_name":"Salem Hasan Abukres","raw_affiliation_strings":["Faculty of pharmacy, Elmergib University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of pharmacy, Elmergib University","institution_ids":["https://openalex.org/I4210148074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021767715","display_name":"Noradeen Hamza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I23906160","display_name":"University of Tripoli","ror":"https://ror.org/00taa2s29","country_code":"LY","type":"education","lineage":["https://openalex.org/I23906160"]},{"id":"https://openalex.org/I4210148074","display_name":"University Elmergib","ror":"https://ror.org/056mwwj30","country_code":"LY","type":"education","lineage":["https://openalex.org/I4210148074"]}],"countries":["LY"],"is_corresponding":false,"raw_author_name":"Noradeen Hamza","raw_affiliation_strings":["( ) Faculty of pharmacy , Elmergib University. (","Faculty of medicine, Tripoli University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"( ) Faculty of pharmacy , Elmergib University. (","institution_ids":["https://openalex.org/I4210148074"]},{"raw_affiliation_string":"Faculty of medicine, Tripoli University","institution_ids":["https://openalex.org/I23906160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048642264","display_name":"Kaled Attomy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I23906160","display_name":"University of Tripoli","ror":"https://ror.org/00taa2s29","country_code":"LY","type":"education","lineage":["https://openalex.org/I23906160"]}],"countries":["LY"],"is_corresponding":false,"raw_author_name":"Kaled Attomy","raw_affiliation_strings":["Faculty of medicine, Tripoli University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of medicine, Tripoli University","institution_ids":["https://openalex.org/I23906160"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058412081","display_name":"Sedki Abdasalam Erwimi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I23906160","display_name":"University of Tripoli","ror":"https://ror.org/00taa2s29","country_code":"LY","type":"education","lineage":["https://openalex.org/I23906160"]}],"countries":["LY"],"is_corresponding":false,"raw_author_name":"Sedki Abdasalam Erwimi","raw_affiliation_strings":["Faculty of medicine, Tripoli University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of medicine, Tripoli University","institution_ids":["https://openalex.org/I23906160"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.23112596,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"4","issue":"1","first_page":"148","last_page":"153"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11815","display_name":"Urological Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erectile-dysfunction","display_name":"erectile dysfunction","score":0.9779999852180481},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.953000009059906},{"id":"https://openalex.org/keywords/sildenafil-citrate","display_name":"sildenafil citrate","score":0.9359999895095825},{"id":"https://openalex.org/keywords/tadalafil","display_name":"tadalafil","score":0.9980000257492065},{"id":"https://openalex.org/keywords/phosphodiesterase-5-inhibitors","display_name":"phosphodiesterase-5 inhibitors","score":0.9900000095367432},{"id":"https://openalex.org/keywords/drug-efficacy","display_name":"drug efficacy","score":0.6000000238418579},{"id":"https://openalex.org/keywords/drug-tolerability","display_name":"drug tolerability","score":0.9259999990463257},{"id":"https://openalex.org/keywords/patient-reported-outcomes","display_name":"patient-reported outcomes","score":0.5180000066757202}],"concepts":[{"id":"https://openalex.org/C2780816001","wikidata":"https://www.wikidata.org/wiki/Q424156","display_name":"Tadalafil","level":3,"score":0.9722474813461304},{"id":"https://openalex.org/C2778375690","wikidata":"https://www.wikidata.org/wiki/Q7814214","display_name":"Tolerability","level":3,"score":0.9110734462738037},{"id":"https://openalex.org/C2779929075","wikidata":"https://www.wikidata.org/wiki/Q184674","display_name":"Erectile dysfunction","level":2,"score":0.8609316349029541},{"id":"https://openalex.org/C2776768464","wikidata":"https://www.wikidata.org/wiki/Q191521","display_name":"Sildenafil","level":2,"score":0.8173013925552368},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.78719162940979},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.5052981972694397},{"id":"https://openalex.org/C74534348","wikidata":"https://www.wikidata.org/wiki/Q410798","display_name":"cGMP-specific phosphodiesterase type 5","level":3,"score":0.4763876795768738},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44087427854537964},{"id":"https://openalex.org/C2778822586","wikidata":"https://www.wikidata.org/wiki/Q424161","display_name":"Vardenafil","level":4,"score":0.4282301366329193},{"id":"https://openalex.org/C87813604","wikidata":"https://www.wikidata.org/wiki/Q1242899","display_name":"Crossover study","level":4,"score":0.42524203658103943},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3787943124771118},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.2384258508682251},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.17121514678001404},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.65137/lmj.v4i1.74","doi":"https://doi.org/10.65137/lmj.v4i1.74","is_oa":true,"landing_page_url":"https://doi.org/10.65137/lmj.v4i1.74","pdf_url":"https://lebmedj.elmergib.edu.ly/index.php/LMJ/article/download/74/31","source":{"id":"https://openalex.org/S5407053242","display_name":"Lebda Medical Journal","issn_l":"2520-0941","issn":["2520-0941","2520-095X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lebda Medical Journal","raw_type":"journal-article"},{"id":"pmh:oai:ojs2.lebmedj.elmergib.edu.ly:article/74","doi":null,"is_oa":false,"landing_page_url":"https://lebmedj.elmergib.edu.ly/index.php/index/article/view/74","pdf_url":null,"source":{"id":"https://openalex.org/S5407053242","display_name":"Lebda Medical Journal","issn_l":"2520-0941","issn":["2520-0941","2520-095X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2520-0941","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.65137/lmj.v4i1.74","doi":"https://doi.org/10.65137/lmj.v4i1.74","is_oa":true,"landing_page_url":"https://doi.org/10.65137/lmj.v4i1.74","pdf_url":"https://lebmedj.elmergib.edu.ly/index.php/LMJ/article/download/74/31","source":{"id":"https://openalex.org/S5407053242","display_name":"Lebda Medical Journal","issn_l":"2520-0941","issn":["2520-0941","2520-095X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lebda Medical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2906659040.pdf","grobid_xml":"https://content.openalex.org/works/W2906659040.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2028224074","https://openalex.org/W2158912475","https://openalex.org/W2053047722","https://openalex.org/W2170259285","https://openalex.org/W4229366275","https://openalex.org/W2006071600","https://openalex.org/W2087345437","https://openalex.org/W2145719022","https://openalex.org/W3131933335","https://openalex.org/W2337264204"],"abstract_inverted_index":{"Introduction:":[0],"Data":[1],"from":[2],"head-to-head":[3],"clinical":[4],"trials":[5],"of":[6,36,59,74,91,153],"phosphodiesterase":[7],"type":[8],"5":[9],"inhibitors":[10],"are":[11,139],"scarce,":[12],"making":[13],"it":[14],"difficult":[15],"for":[16,24,102,123,130],"clinicians":[17],"to":[18,82],"select":[19],"the":[20,84,104,131,134,170,195,205],"most":[21],"appropriate":[22],"treatment":[23],"their":[25],"patients":[26,61],"with":[27,42,173],"erectile":[28,43],"dysfunction.":[29],"Aim:":[30],"To":[31],"compare":[32,87],"efficacy":[33,88],"and":[34,38,45,51,65,71,78,86,89,118,129,147,161,194],"tolerability":[35,90],"Sildenafil":[37,75],"Tadalafil":[39,79,117,146,174],"in":[40,114,143,151,164,179,189],"men":[41],"dysfunction":[44],"diabetes.":[46],"Method:":[47],"A":[48,57],"clinical,":[49],"crossover":[50],"open":[52],"label":[53],"study":[54],"was":[55,175,208],"used.":[56],"group":[58],"95":[60],"were":[62,158,186],"randomly":[63],"recruited":[64],"answered":[66],"an":[67],"adapted":[68],"questionnaire":[69],"before":[70],"after":[72,127,192],"usage":[73],"100":[76],"mg":[77,81],"20":[80],"determine":[83],"improvement":[85],"each":[92],"drug.":[93],"RESULTS:":[94],"The":[95],"one":[96],"tailed":[97],"Wilcoxon":[98],"signed-rank":[99],"test":[100],"results":[101,135],"all":[103,180],"questions":[105],"suggest":[106,136],"that":[107,137],"there":[108,138],"is":[109],"no":[110],"statistically":[111,140,183],"significant":[112,141,184],"difference":[113],"response":[115,144],"between":[116,145],"sildenafil":[119,148,178],"p":[120,149],">0.05.":[121],"However,":[122,182],"erection":[124,171],"maintenance":[125,190],"ability":[126,191],"penetration":[128,193],"overall":[132,196],"response,":[133],"differences":[142,185],"<0.05":[150],"favor":[152],"Tadalafil.":[154],"Conclusion:":[155],"Both":[156],"drugs":[157],"highly":[159],"effective":[160],"well":[162],"tolerated":[163],"diabetic":[165],"patients.":[166],"Patient\u2019s":[167],"score":[168],"on":[169],"scale":[172],"superior":[176],"than":[177],"questions.":[181],"only":[187],"detected":[188,203],"response.":[197],"Probably,":[198],"more":[199],"significance":[200],"could":[201],"be":[202],"if":[204],"sample":[206],"size":[207],"larger.":[209]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2019-01-01T00:00:00"}