{"id":"https://openalex.org/W2906354584","doi":"https://doi.org/10.1016/j.rbmo.2018.12.014","title":"Prolonged blastomere movement induced by the delay of pronuclear fading and first cell division adversely affects pregnancy outcomes after fresh embryo transfer on Day 2: a time-lapse study","display_name":"Prolonged blastomere movement induced by the delay of pronuclear fading and first cell division adversely affects pregnancy outcomes after fresh embryo transfer on Day 2: a time-lapse study","publication_year":2018,"publication_date":"2018-12-22","ids":{"openalex":"https://openalex.org/W2906354584","doi":"https://doi.org/10.1016/j.rbmo.2018.12.014","mag":"2906354584","pmid":"https://pubmed.ncbi.nlm.nih.gov/30853350"},"language":"en","primary_location":{"id":"doi:10.1016/j.rbmo.2018.12.014","doi":"https://doi.org/10.1016/j.rbmo.2018.12.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.rbmo.2018.12.014","pdf_url":null,"source":{"id":"https://openalex.org/S206719219","display_name":"Reproductive BioMedicine Online","issn_l":"1472-6483","issn":["1472-6483","1472-6491"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive BioMedicine Online","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006470247","display_name":"Kenji Ezoe","orcid":"https://orcid.org/0000-0002-3778-2259","observed_orcids":["https://orcid.org/0000-0002-3778-2259"]},"institutions":[{"id":"https://openalex.org/I4405256189","display_name":"Kato Ladies Clinic","ror":"https://ror.org/03w63ta28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256189"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kenji Ezoe","raw_affiliation_strings":["Kato Ladies Clinic, Tokyo 160-0023, Japan. Electronic address: k-ezoe@towako-kato.com","Kato Ladies Clinic, Tokyo 160-0023, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan. Electronic address: k-ezoe@towako-kato.com","institution_ids":["https://openalex.org/I4405256189"]},{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan","institution_ids":["https://openalex.org/I4405256189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060789520","display_name":"Kazuki Ohata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256189","display_name":"Kato Ladies Clinic","ror":"https://ror.org/03w63ta28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256189"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuki Ohata","raw_affiliation_strings":["Kato Ladies Clinic, Tokyo 160-0023, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan","institution_ids":["https://openalex.org/I4405256189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110366404","display_name":"Hirofumi Morita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256189","display_name":"Kato Ladies Clinic","ror":"https://ror.org/03w63ta28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256189"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirofumi Morita","raw_affiliation_strings":["Kato Ladies Clinic, Tokyo 160-0023, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan","institution_ids":["https://openalex.org/I4405256189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044092744","display_name":"Satoshi Ueno","orcid":"https://orcid.org/0000-0002-4021-6602","observed_orcids":["https://orcid.org/0000-0002-4021-6602"]},"institutions":[{"id":"https://openalex.org/I4405256189","display_name":"Kato Ladies Clinic","ror":"https://ror.org/03w63ta28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256189"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Satoshi Ueno","raw_affiliation_strings":["Kato Ladies Clinic, Tokyo 160-0023, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan","institution_ids":["https://openalex.org/I4405256189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058648042","display_name":"Tetsuya Miki","orcid":"https://orcid.org/0000-0003-0563-5358","observed_orcids":["https://orcid.org/0000-0003-0563-5358"]},"institutions":[{"id":"https://openalex.org/I4405256189","display_name":"Kato Ladies Clinic","ror":"https://ror.org/03w63ta28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256189"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tetsuya Miki","raw_affiliation_strings":["Kato Ladies Clinic, Tokyo 160-0023, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan","institution_ids":["https://openalex.org/I4405256189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063677105","display_name":"Tadashi Okimura","orcid":"https://orcid.org/0000-0002-8006-5220","observed_orcids":["https://orcid.org/0000-0002-8006-5220"]},"institutions":[{"id":"https://openalex.org/I4405256189","display_name":"Kato Ladies Clinic","ror":"https://ror.org/03w63ta28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256189"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tadashi Okimura","raw_affiliation_strings":["Kato Ladies Clinic, Tokyo 160-0023, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan","institution_ids":["https://openalex.org/I4405256189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105886294","display_name":"Kazuo Uchiyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256189","display_name":"Kato Ladies Clinic","ror":"https://ror.org/03w63ta28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256189"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuo Uchiyama","raw_affiliation_strings":["Kato Ladies Clinic, Tokyo 160-0023, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan","institution_ids":["https://openalex.org/I4405256189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000755236","display_name":"Akiko Yabuuchi","orcid":"https://orcid.org/0000-0003-4160-310X","observed_orcids":["https://orcid.org/0000-0003-4160-310X"]},"institutions":[{"id":"https://openalex.org/I4405256189","display_name":"Kato Ladies Clinic","ror":"https://ror.org/03w63ta28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256189"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akiko Yabuuchi","raw_affiliation_strings":["Kato Ladies Clinic, Tokyo 160-0023, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan","institution_ids":["https://openalex.org/I4405256189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010703830","display_name":"Tamotsu Kobayashi","orcid":"https://orcid.org/0000-0002-2437-8054","observed_orcids":["https://orcid.org/0000-0002-2437-8054"]},"institutions":[{"id":"https://openalex.org/I4405256189","display_name":"Kato Ladies Clinic","ror":"https://ror.org/03w63ta28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256189"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tamotsu Kobayashi","raw_affiliation_strings":["Kato Ladies Clinic, Tokyo 160-0023, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan","institution_ids":["https://openalex.org/I4405256189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054357651","display_name":"Markus H. M. Montag","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Markus Montag","raw_affiliation_strings":["ilabcomm GmbH, Eisenachstrasse 34, St. Augustin 53757, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ilabcomm GmbH, Eisenachstrasse 34, St. Augustin 53757, Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050326833","display_name":"Keiichi Kato","orcid":"https://orcid.org/0000-0002-1394-4532","observed_orcids":["https://orcid.org/0000-0002-1394-4532"]},"institutions":[{"id":"https://openalex.org/I4405256189","display_name":"Kato Ladies Clinic","ror":"https://ror.org/03w63ta28","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405256189"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Keiichi Kato","raw_affiliation_strings":["Kato Ladies Clinic, Tokyo 160-0023, Japan. Electronic address: k-kato@towako.net","Kato Ladies Clinic, Tokyo 160-0023, Japan"],"raw_orcid":"https://orcid.org/0000-0002-1394-4532","affiliations":[{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan. Electronic address: k-kato@towako.net","institution_ids":["https://openalex.org/I4405256189"]},{"raw_affiliation_string":"Kato Ladies Clinic, Tokyo 160-0023, Japan","institution_ids":["https://openalex.org/I4405256189"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5006470247","https://openalex.org/A5050326833"],"corresponding_institution_ids":["https://openalex.org/I4405256189"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":null,"fwci":3.7106,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.93684211,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"38","issue":"5","first_page":"659","last_page":"668"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.9394999742507935,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.9394999742507935,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11732","display_name":"Assisted Reproductive Technology and Twin Pregnancy","score":0.024399999529123306,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.00989999994635582,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/first-cell-division","display_name":"first cell division","score":0.8399999737739563},{"id":"https://openalex.org/keywords/embryonic-cleavage","display_name":"embryo cleavage","score":0.5339999794960022},{"id":"https://openalex.org/keywords/embryo-selection","display_name":"embryo selection","score":0.4959999918937683},{"id":"https://openalex.org/keywords/ongoing-pregnancy-rate","display_name":"ongoing pregnancy rate","score":0.7919999957084656},{"id":"https://openalex.org/keywords/embryo-developmental-competence","display_name":"embryo developmental competence","score":0.44999998807907104},{"id":"https://openalex.org/keywords/embryo-fragmentation","display_name":"embryo fragmentation","score":0.6309999823570251},{"id":"https://openalex.org/keywords/time-lapse-embryo-monitoring","display_name":"time-lapse embryo imaging","score":0.6919999718666077},{"id":"https://openalex.org/keywords/day-2-embryo-transfer","display_name":"day 2 embryo transfer","score":0.6980000138282776}],"concepts":[{"id":"https://openalex.org/C68760520","wikidata":"https://www.wikidata.org/wiki/Q882097","display_name":"Blastomere","level":4,"score":0.8475110530853271},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.7042828798294067},{"id":"https://openalex.org/C160099875","wikidata":"https://www.wikidata.org/wiki/Q237118","display_name":"Embryo transfer","level":3,"score":0.6583554744720459},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.6504091620445251},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4774540066719055},{"id":"https://openalex.org/C85813293","wikidata":"https://www.wikidata.org/wiki/Q188909","display_name":"Cell division","level":3,"score":0.45903468132019043},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.45878368616104126},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.37755411863327026},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3081498146057129},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2600101828575134},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.23999720811843872},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1544196903705597}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001757","descriptor_name":"Blastomeres","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004624","descriptor_name":"Embryo Transfer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011256","descriptor_name":"Pregnancy Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.rbmo.2018.12.014","doi":"https://doi.org/10.1016/j.rbmo.2018.12.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.rbmo.2018.12.014","pdf_url":null,"source":{"id":"https://openalex.org/S206719219","display_name":"Reproductive BioMedicine Online","issn_l":"1472-6483","issn":["1472-6483","1472-6491"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive BioMedicine Online","raw_type":"journal-article"},{"id":"pmid:30853350","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30853350","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproductive biomedicine online","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":58,"referenced_works":["https://openalex.org/W1882638238","https://openalex.org/W1964164411","https://openalex.org/W1964465516","https://openalex.org/W1975388194","https://openalex.org/W1976144595","https://openalex.org/W1981323432","https://openalex.org/W1982541924","https://openalex.org/W1987440412","https://openalex.org/W1987614027","https://openalex.org/W1990841625","https://openalex.org/W1993464648","https://openalex.org/W1996115067","https://openalex.org/W2003049716","https://openalex.org/W2003536491","https://openalex.org/W2003987246","https://openalex.org/W2005223627","https://openalex.org/W2009434612","https://openalex.org/W2021794273","https://openalex.org/W2029465329","https://openalex.org/W2034107956","https://openalex.org/W2037561836","https://openalex.org/W2048070648","https://openalex.org/W2048938594","https://openalex.org/W2051741587","https://openalex.org/W2052627453","https://openalex.org/W2053504405","https://openalex.org/W2057755432","https://openalex.org/W2064658390","https://openalex.org/W2080018890","https://openalex.org/W2084069645","https://openalex.org/W2084301726","https://openalex.org/W2096243172","https://openalex.org/W2099496651","https://openalex.org/W2102752109","https://openalex.org/W2109050567","https://openalex.org/W2118040134","https://openalex.org/W2118583367","https://openalex.org/W2119735653","https://openalex.org/W2124381929","https://openalex.org/W2130126684","https://openalex.org/W2137250627","https://openalex.org/W2152789976","https://openalex.org/W2153736963","https://openalex.org/W2156139452","https://openalex.org/W2163799086","https://openalex.org/W2204377200","https://openalex.org/W2255537226","https://openalex.org/W2466684180","https://openalex.org/W2587723625","https://openalex.org/W2606821096","https://openalex.org/W2735231143","https://openalex.org/W2755754837","https://openalex.org/W2761490012","https://openalex.org/W2765461842","https://openalex.org/W2769628447","https://openalex.org/W2769923338","https://openalex.org/W2799292538","https://openalex.org/W4247850956"],"related_works":["https://openalex.org/W2946941385","https://openalex.org/W7117337366","https://openalex.org/W2009434612","https://openalex.org/W3132261985","https://openalex.org/W2754900231","https://openalex.org/W1868102502","https://openalex.org/W2345025153","https://openalex.org/W7127995236","https://openalex.org/W6958644908","https://openalex.org/W2040114341"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-01-01T00:00:00"}