{"id":"https://openalex.org/W2906213965","doi":"https://doi.org/10.1002/cbin.11294","title":"Ozone alleviates ischemia/reperfusion injury by inhibiting mitochondrion\u2010mediated apoptosis pathway in SH\u2010SY5Y cells","display_name":"Ozone alleviates ischemia/reperfusion injury by inhibiting mitochondrion\u2010mediated apoptosis pathway in SH\u2010SY5Y cells","publication_year":2019,"publication_date":"2019-12-27","ids":{"openalex":"https://openalex.org/W2906213965","doi":"https://doi.org/10.1002/cbin.11294","mag":"2906213965","pmid":"https://pubmed.ncbi.nlm.nih.gov/31880362"},"language":"en","primary_location":{"id":"doi:10.1002/cbin.11294","doi":"https://doi.org/10.1002/cbin.11294","is_oa":false,"landing_page_url":"https://doi.org/10.1002/cbin.11294","pdf_url":null,"source":{"id":"https://openalex.org/S7325069","display_name":"Cell Biology International","issn_l":"1065-6995","issn":["1065-6995","1095-8355"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Biology International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112314311","display_name":"Hua\u2010An Cai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]},{"id":"https://openalex.org/I4210147389","display_name":"Hunan Provincial People's Hospital","ror":"https://ror.org/03wwr4r78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147389"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hua\u2010An Cai","raw_affiliation_strings":["Department of Rehabilitative Medicine, Laboratory of Sports Medicine Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University  Changsha 410016 P.R. China","Department of Rehabilitative Medicine, Laboratory of Sports Medicine, Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University, Changsha, 410016 P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rehabilitative Medicine, Laboratory of Sports Medicine Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University  Changsha 410016 P.R. China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I4210147389"]},{"raw_affiliation_string":"Department of Rehabilitative Medicine, Laboratory of Sports Medicine, Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University, Changsha, 410016 P.R. China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I4210147389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042957245","display_name":"Xi Tao","orcid":"https://orcid.org/0000-0001-9606-6140","observed_orcids":["https://orcid.org/0000-0001-9606-6140"]},"institutions":[{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]},{"id":"https://openalex.org/I4210147389","display_name":"Hunan Provincial People's Hospital","ror":"https://ror.org/03wwr4r78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147389"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xi Tao","raw_affiliation_strings":["Department of Rehabilitative Medicine Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University  Changsha 410016 P.R. China","Department of Rehabilitative Medicine, Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University, Changsha, 410016 P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rehabilitative Medicine Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University  Changsha 410016 P.R. China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I4210147389"]},{"raw_affiliation_string":"Department of Rehabilitative Medicine, Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University, Changsha, 410016 P.R. China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I4210147389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101245544","display_name":"Lijun Zheng","orcid":"https://orcid.org/0009-0001-8477-6329","observed_orcids":["https://orcid.org/0009-0001-8477-6329"]},"institutions":[{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]},{"id":"https://openalex.org/I4210147389","display_name":"Hunan Provincial People's Hospital","ror":"https://ror.org/03wwr4r78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147389"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li\u2010Jun Zheng","raw_affiliation_strings":["Department of Rehabilitative Medicine Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University  Changsha 410016 P.R. China","Department of Rehabilitative Medicine, Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University, Changsha, 410016 P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rehabilitative Medicine Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University  Changsha 410016 P.R. China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I4210147389"]},{"raw_affiliation_string":"Department of Rehabilitative Medicine, Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University, Changsha, 410016 P.R. China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I4210147389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055807567","display_name":"Liang Huang","orcid":"https://orcid.org/0000-0002-8370-3232","observed_orcids":["https://orcid.org/0000-0002-8370-3232"]},"institutions":[{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]},{"id":"https://openalex.org/I4210147389","display_name":"Hunan Provincial People's Hospital","ror":"https://ror.org/03wwr4r78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147389"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Huang","raw_affiliation_strings":["Department of Rehabilitative Medicine Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University  Changsha 410016 P.R. China","Department of Rehabilitative Medicine, Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University, Changsha, 410016 P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rehabilitative Medicine Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University  Changsha 410016 P.R. China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I4210147389"]},{"raw_affiliation_string":"Department of Rehabilitative Medicine, Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University, Changsha, 410016 P.R. China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I4210147389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067686114","display_name":"Yan Peng","orcid":"https://orcid.org/0000-0001-6579-3409","observed_orcids":["https://orcid.org/0000-0001-6579-3409"]},"institutions":[{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]},{"id":"https://openalex.org/I4210147389","display_name":"Hunan Provincial People's Hospital","ror":"https://ror.org/03wwr4r78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147389"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Peng","raw_affiliation_strings":["Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University  Changsha 410016 P.R. China","Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University, Changsha, 410016 P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University  Changsha 410016 P.R. China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I4210147389"]},{"raw_affiliation_string":"Hunan Provincial People's Hospital and The First Affiliated Hospital of Hunan Normal University, Changsha, 410016 P.R. China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I4210147389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010758030","display_name":"Ruo\u2010Yi Liao","orcid":"https://orcid.org/0000-0002-4506-5217","observed_orcids":["https://orcid.org/0000-0002-4506-5217"]},"institutions":[{"id":"https://openalex.org/I14992734","display_name":"Hunan University of Traditional Chinese Medicine","ror":"https://ror.org/05qfq0x09","country_code":"CN","type":"education","lineage":["https://openalex.org/I14992734"]},{"id":"https://openalex.org/I4210104845","display_name":"First Affiliated Hospital of Hunan University of Traditional Chinese Medicine","ror":"https://ror.org/01ffek432","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210104845"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ruo\u2010Yi Liao","raw_affiliation_strings":["Department of Nursing The First Hospital of Hunan University of Chinese Medicine  Changsha 410007 P.R. China","Department of Nursing, The First Hospital of Hunan University of Chinese Medicine, Changsha, 410007 P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nursing The First Hospital of Hunan University of Chinese Medicine  Changsha 410007 P.R. China","institution_ids":["https://openalex.org/I14992734","https://openalex.org/I4210104845"]},{"raw_affiliation_string":"Department of Nursing, The First Hospital of Hunan University of Chinese Medicine, Changsha, 410007 P.R. China","institution_ids":["https://openalex.org/I4210104845"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5115603707","display_name":"Yi-min Zhu","orcid":"https://orcid.org/0000-0002-6353-251X","observed_orcids":["https://orcid.org/0000-0002-6353-251X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Yi\u2010Min Zhu","raw_affiliation_strings":["Hunan Provincial Key Laboratory of Emergency and Critical Care Metabonomics  Changsha 410005 P.R. China","Hunan Provincial Key Laboratory of Emergency and Critical Care Metabonomics, Changsha, 410005 P.R. China"],"raw_orcid":"https://orcid.org/0000-0002-6353-251X","affiliations":[{"raw_affiliation_string":"Hunan Provincial Key Laboratory of Emergency and Critical Care Metabonomics  Changsha 410005 P.R. China","institution_ids":[]},{"raw_affiliation_string":"Hunan Provincial Key Laboratory of Emergency and Critical Care Metabonomics, Changsha, 410005 P.R. China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5010758030","https://openalex.org/A5115603707"],"corresponding_institution_ids":["https://openalex.org/I14992734","https://openalex.org/I4210104845"],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":3.0115,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.91252919,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"44","issue":"4","first_page":"975","last_page":"984"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13365","display_name":"Medical and Biological Ozone Research","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13365","display_name":"Medical and Biological Ozone Research","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13796","display_name":"Neurological Disorders and Treatments","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ozone","display_name":"ozone","score":0.8050000071525574},{"id":"https://openalex.org/keywords/cerebral-ischemia-reperfusion-injury","display_name":"cerebral ischemia-reperfusion injury","score":0.9890000224113464},{"id":"https://openalex.org/keywords/mitochondrial-apoptosis","display_name":"mitochondrial apoptosis","score":0.7490000128746033},{"id":"https://openalex.org/keywords/sh-sy5y-cells","display_name":"SH-SY5Y cells","score":0.9779999852180481},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.824999988079071},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8299999833106995},{"id":"https://openalex.org/keywords/redox-homeostasis","display_name":"redox homeostasis","score":0.8870000243186951},{"id":"https://openalex.org/keywords/cytochrome-c-release","display_name":"cytochrome c release","score":0.9020000100135803},{"id":"https://openalex.org/keywords/bcl-2-bax-ratio","display_name":"Bcl-2/Bax ratio","score":0.9160000085830688},{"id":"https://openalex.org/keywords/caspase-signaling","display_name":"caspase signaling","score":0.9729999899864197},{"id":"https://openalex.org/keywords/mitochondrial-membrane-potential","display_name":"mitochondrial membrane potential","score":0.7239999771118164}],"concepts":[{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.673976719379425},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.6636593341827393},{"id":"https://openalex.org/C29311851","wikidata":"https://www.wikidata.org/wiki/Q408223","display_name":"Cytochrome c","level":3,"score":0.6478519439697266},{"id":"https://openalex.org/C2779083432","wikidata":"https://www.wikidata.org/wiki/Q7390126","display_name":"SH-SY5Y","level":4,"score":0.6051971912384033},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.5400067567825317},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5214561820030212},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.4702754616737366},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.45672306418418884},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4060928225517273},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30996468663215637},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.1384219527244568},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C2776715637","wikidata":"https://www.wikidata.org/wiki/Q938205","display_name":"Neuroblastoma","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010126","descriptor_name":"Ozone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010126","descriptor_name":"Ozone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010126","descriptor_name":"Ozone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015427","descriptor_name":"Reperfusion Injury","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D015427","descriptor_name":"Reperfusion Injury","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D015427","descriptor_name":"Reperfusion Injury","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053078","descriptor_name":"Membrane Potential, Mitochondrial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053078","descriptor_name":"Membrane Potential, Mitochondrial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053078","descriptor_name":"Membrane Potential, Mitochondrial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/cbin.11294","doi":"https://doi.org/10.1002/cbin.11294","is_oa":false,"landing_page_url":"https://doi.org/10.1002/cbin.11294","pdf_url":null,"source":{"id":"https://openalex.org/S7325069","display_name":"Cell Biology International","issn_l":"1065-6995","issn":["1065-6995","1095-8355"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Biology International","raw_type":"journal-article"},{"id":"pmid:31880362","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31880362","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell biology international","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8560000061988831}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4099999964237213}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W2005223534","https://openalex.org/W2009832392","https://openalex.org/W2026271757","https://openalex.org/W2026964236","https://openalex.org/W2028934633","https://openalex.org/W2054269585","https://openalex.org/W2061277533","https://openalex.org/W2090203830","https://openalex.org/W2096944502","https://openalex.org/W2100535000","https://openalex.org/W2114714043","https://openalex.org/W2132505310","https://openalex.org/W2157166559","https://openalex.org/W2161285579","https://openalex.org/W2165926538","https://openalex.org/W2181425336","https://openalex.org/W2271113257","https://openalex.org/W2313659506","https://openalex.org/W2482498495","https://openalex.org/W2522238820","https://openalex.org/W2536110660","https://openalex.org/W2580794219","https://openalex.org/W2586378720","https://openalex.org/W2593605822","https://openalex.org/W2606349540","https://openalex.org/W2607709076","https://openalex.org/W2719401943","https://openalex.org/W2789293914","https://openalex.org/W2804823070","https://openalex.org/W2885258677","https://openalex.org/W2895941088","https://openalex.org/W2896039849","https://openalex.org/W2941382852"],"related_works":["https://openalex.org/W2378662303","https://openalex.org/W2409084429","https://openalex.org/W2042969785","https://openalex.org/W2385502310","https://openalex.org/W2368734402","https://openalex.org/W4311600904","https://openalex.org/W3030252301","https://openalex.org/W2024533066","https://openalex.org/W2581455006","https://openalex.org/W2517906103"],"abstract_inverted_index":{"Abstract":[0],"Cerebral":[1],"ischemia/reperfusion":[2],"(I/R)":[3],"injuries":[4],"are":[5],"common":[6],"and":[7,38,53,70,96,109,121,133,144,167,178,197],"often":[8],"cause":[9],"severe":[10],"complications.":[11],"Ozone":[12,124,136,186],"has":[13,187],"been":[14],"applied":[15],"for":[16],"protecting":[17],"I/R":[18,142,162,214],"injury":[19,143],"in":[20,93,154,183],"animal":[21],"models":[22],"of":[23,48,55,148,176,190],"several":[24],"organs":[25],"including":[26],"cerebra,":[27],"but":[28],"the":[29,46,94,146,174,188],"detailed":[30],"mechanism":[31],"remains":[32],"unclear.":[33],"3\u2010(4,5\u2010Dimethylthiazol\u20102\u2010yl)\u20102,5\u2010diphenyltetrazolium":[34],"bromide":[35],"(MTT)":[36],"assay":[37],"lactate":[39],"dehydrogenase":[40],"measurement":[41],"were":[42,74,113],"used":[43],"to":[44,152],"determine":[45],"influence":[47],"ozone":[49,168,205],"on":[50],"cell":[51,158],"activity":[52],"damage":[54,127,139],"SH\u2010SY5Y":[56,155,184],"cells.":[57,156,185],"Some":[58],"redox":[59,192],"items":[60],"such":[61],"as":[62],"catalase":[63],"(CAT),":[64],"malondialdehyde":[65],"(MDA),":[66],"glutathione":[67],"peroxidase":[68],"(GSH\u2010Px),":[69],"superoxide":[71],"dismutase":[72],"(SOD)":[73],"measured":[75,99],"by":[76,87,100,106,115,128,141,161,165,172,202],"enzyme\u2010linked":[77],"immunosorbent":[78],"assay.":[79,89],"The":[80,157],"mitochondrial":[81,138],"membrane":[82],"potential":[83],"(\u0394\u03a8m)":[84],"was":[85,98,104,163],"determined":[86,105],"JC\u20101":[88],"Cytochrome\u2010c":[90],"(cyt\u2010c)":[91],"level":[92],"cytoplasm":[95,153],"mitochondrion":[97,151,195],"western":[101,122],"blotting.":[102,123],"Apoptosis":[103],"flow":[107],"cytometry,":[108],"some":[110],"apoptosis\u2010related":[111],"molecules":[112],"detected":[114],"quantitative":[116],"real\u2010time":[117],"polymerase":[118],"chain":[119],"reaction":[120],"alleviated":[125],"oxidative":[126],"increasing":[129,173],"GSH\u2010Px,":[130],"SOD,":[131],"CAT,":[132],"decreasing":[134,194],"MDA.":[135],"decreased":[137],"caused":[140,160],"inhibited":[145,164],"release":[147],"cyt\u2010c":[149],"from":[150],"apoptosis":[159,171,200],"ozone,":[166],"could":[169],"decrease":[170],"ratio":[175],"Bcl\u20102/Bax":[177],"inhibiting":[179,198],"caspase":[180],"signaling":[181],"pathway":[182],"ability":[189],"maintaining":[191],"homeostasis,":[193],"damage,":[196],"neurocytes":[199],"induced":[201],"I/R.":[203],"Therefore,":[204],"may":[206],"be":[207],"a":[208],"promising":[209],"protective":[210],"strategy":[211],"against":[212],"cerebral":[213],"injury.":[215]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3}],"updated_date":"2026-09-23T05:00:35.095934","created_date":"2025-10-10T00:00:00"}