{"id":"https://openalex.org/W2906119558","doi":"https://doi.org/10.1080/15384101.2018.1558872","title":"Long noncoding RNA PCAT6 inhibits colon cancer cell apoptosis by regulating anti-apoptotic protein ARC expression via EZH2","display_name":"Long noncoding RNA PCAT6 inhibits colon cancer cell apoptosis by regulating anti-apoptotic protein ARC expression via EZH2","publication_year":2018,"publication_date":"2018-12-20","ids":{"openalex":"https://openalex.org/W2906119558","doi":"https://doi.org/10.1080/15384101.2018.1558872","mag":"2906119558","pmid":"https://pubmed.ncbi.nlm.nih.gov/30569799","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6343696"},"language":"en","primary_location":{"id":"doi:10.1080/15384101.2018.1558872","doi":"https://doi.org/10.1080/15384101.2018.1558872","is_oa":true,"landing_page_url":"https://doi.org/10.1080/15384101.2018.1558872","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/15384101.2018.1558872?needAccess=true&role=button","source":{"id":"https://openalex.org/S86011449","display_name":"Cell Cycle","issn_l":"1538-4101","issn":["1538-4101","1551-4005"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Cycle","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.1080/15384101.2018.1558872?needAccess=true&role=button","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018783931","display_name":"Weimei Huang","orcid":"https://orcid.org/0000-0002-2478-284X","observed_orcids":["https://orcid.org/0000-0002-2478-284X"]},"institutions":[{"id":"https://openalex.org/I4210120929","display_name":"Zhujiang Hospital","ror":"https://ror.org/02mhxa927","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210120929"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weimei Huang","raw_affiliation_strings":["Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I4210120929","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004039894","display_name":"Geng Su","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Geng Su","raw_affiliation_strings":["Department of Pathology, Minzu Hospital of Guangxi Zhuang Autonomous Region, Nanning, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Minzu Hospital of Guangxi Zhuang Autonomous Region, Nanning, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109582920","display_name":"Xiaoxian Huang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaoxian Huang","raw_affiliation_strings":["Clinical Laboratory, Gushang Hospital of Guangxi Zhuang Autonomous Region, Nanning, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Laboratory, Gushang Hospital of Guangxi Zhuang Autonomous Region, Nanning, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Angru Zou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Angru Zou","raw_affiliation_strings":["Department of Emergency, Minzu Hospital of Guangxi Zhuang Autonomous Region, Nanning, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency, Minzu Hospital of Guangxi Zhuang Autonomous Region, Nanning, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113966938","display_name":"Jingfang Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210120929","display_name":"Zhujiang Hospital","ror":"https://ror.org/02mhxa927","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210120929"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingfang Wu","raw_affiliation_strings":["Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I4210120929","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023866131","display_name":"Yunchu Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210120929","display_name":"Zhujiang Hospital","ror":"https://ror.org/02mhxa927","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210120929"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yunchu Yang","raw_affiliation_strings":["Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I4210120929","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013749731","display_name":"Yaru Zhu","orcid":"https://orcid.org/0009-0001-3441-2025","observed_orcids":["https://orcid.org/0009-0001-3441-2025"]},"institutions":[{"id":"https://openalex.org/I4210120929","display_name":"Zhujiang Hospital","ror":"https://ror.org/02mhxa927","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210120929"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaru Zhu","raw_affiliation_strings":["Department of Cerebral Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cerebral Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I4210120929","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031990387","display_name":"Shumei Liang","orcid":"https://orcid.org/0000-0001-9326-3907","observed_orcids":["https://orcid.org/0000-0001-9326-3907"]},"institutions":[{"id":"https://openalex.org/I4210120929","display_name":"Zhujiang Hospital","ror":"https://ror.org/02mhxa927","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210120929"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shumei Liang","raw_affiliation_strings":["Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I4210120929","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Deyu Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143087","display_name":"Fujian Provincial Hospital","ror":"https://ror.org/045wzwx52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143087"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Deyu Li","raw_affiliation_strings":["Department of Oncology, Fujian Provincial Hospital, Fuzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Fujian Provincial Hospital, Fuzhou, China","institution_ids":["https://openalex.org/I4210143087"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024131822","display_name":"Feng Ma","orcid":"https://orcid.org/0000-0002-2975-0118","observed_orcids":["https://orcid.org/0000-0002-2975-0118"]},"institutions":[{"id":"https://openalex.org/I169071405","display_name":"Hebei North University","ror":"https://ror.org/03hqwnx39","country_code":"CN","type":"education","lineage":["https://openalex.org/I169071405"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Feng Ma","raw_affiliation_strings":["Department of Oncology, The First Affiliated Hospital of Hebei North University, Zhangjiakou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The First Affiliated Hospital of Hebei North University, Zhangjiakou, China","institution_ids":["https://openalex.org/I169071405"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008538825","display_name":"Linlang Guo","orcid":"https://orcid.org/0000-0002-1859-7592","observed_orcids":["https://orcid.org/0000-0002-1859-7592"]},"institutions":[{"id":"https://openalex.org/I4210120929","display_name":"Zhujiang Hospital","ror":"https://ror.org/02mhxa927","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210120929"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Linlang Guo","raw_affiliation_strings":["Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I4210120929","https://openalex.org/I58200834"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5008538825","https://openalex.org/A5024131822"],"corresponding_institution_ids":["https://openalex.org/I169071405","https://openalex.org/I4210120929","https://openalex.org/I58200834"],"apc_list":null,"apc_paid":null,"fwci":2.7133,"has_fulltext":true,"cited_by_count":58,"citation_normalized_percentile":{"value":0.92201304,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"18","issue":"1","first_page":"69","last_page":"83"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-intergenic-noncoding-rna","display_name":"long intergenic non-coding RNA","score":0.9470000267028809},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.8669999837875366},{"id":"https://openalex.org/keywords/arc","display_name":"Arc","score":0.8169999718666077},{"id":"https://openalex.org/keywords/ezh2","display_name":"EZH2","score":0.9900000095367432},{"id":"https://openalex.org/keywords/h3k4me3","display_name":"H3K4me3","score":0.9929999709129333},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.777999997138977},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.7379999756813049},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9800000190734863},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.9369999766349792}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.795280933380127},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6123101115226746},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.5764404535293579},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5708112716674805},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.4820998013019562},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12767013907432556},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12653127312660217}],"mesh":[{"descriptor_ui":"D000071221","descriptor_name":"Enhancer of Zeste Homolog 2 Protein","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003598","descriptor_name":"Cytoskeletal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D045325","descriptor_name":"HCT116 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D064593","descriptor_name":"Heterografts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1080/15384101.2018.1558872","doi":"https://doi.org/10.1080/15384101.2018.1558872","is_oa":true,"landing_page_url":"https://doi.org/10.1080/15384101.2018.1558872","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/15384101.2018.1558872?needAccess=true&role=button","source":{"id":"https://openalex.org/S86011449","display_name":"Cell Cycle","issn_l":"1538-4101","issn":["1538-4101","1551-4005"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Cycle","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6343696","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6343696","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Cycle","raw_type":"Text"},{"id":"pmid:30569799","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30569799","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell cycle (Georgetown, Tex.)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1080/15384101.2018.1558872","doi":"https://doi.org/10.1080/15384101.2018.1558872","is_oa":true,"landing_page_url":"https://doi.org/10.1080/15384101.2018.1558872","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/15384101.2018.1558872?needAccess=true&role=button","source":{"id":"https://openalex.org/S86011449","display_name":"Cell Cycle","issn_l":"1538-4101","issn":["1538-4101","1551-4005"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Cycle","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"No poverty","score":0.6899999976158142,"id":"https://metadata.un.org/sdg/1"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5568371977","display_name":null,"funder_award_id":"No.81572244","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8647103113","display_name":null,"funder_award_id":"81572244","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321160","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71"},{"id":"https://openalex.org/F4320335744","display_name":"Guangxi Zhuang Autonomous Region Health and Family Planning Commission","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2906119558.pdf","grobid_xml":"https://content.openalex.org/works/W2906119558.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W1830146239","https://openalex.org/W1966976790","https://openalex.org/W1973370476","https://openalex.org/W1987584325","https://openalex.org/W2002039365","https://openalex.org/W2022484555","https://openalex.org/W2033278690","https://openalex.org/W2041115282","https://openalex.org/W2067768332","https://openalex.org/W2070479140","https://openalex.org/W2089288158","https://openalex.org/W2097625578","https://openalex.org/W2097786201","https://openalex.org/W2106787323","https://openalex.org/W2130493280","https://openalex.org/W2149386057","https://openalex.org/W2149821525","https://openalex.org/W2158898099","https://openalex.org/W2167122624","https://openalex.org/W2221837786","https://openalex.org/W2229833364","https://openalex.org/W2526873982","https://openalex.org/W2580890017","https://openalex.org/W2594373254","https://openalex.org/W2608729572","https://openalex.org/W2755489436","https://openalex.org/W2765313162","https://openalex.org/W2784570320","https://openalex.org/W2791229945","https://openalex.org/W2795075229","https://openalex.org/W2797123860","https://openalex.org/W2917837889"],"related_works":["https://openalex.org/W4392301552","https://openalex.org/W4392657443","https://openalex.org/W3215346382","https://openalex.org/W4406519398","https://openalex.org/W3133617041","https://openalex.org/W2750741687","https://openalex.org/W3178064251","https://openalex.org/W3188752936","https://openalex.org/W2985460144","https://openalex.org/W2897443184"],"abstract_inverted_index":{"Prostate":[0],"cancer-associated":[1],"ncRNA":[2],"transcript":[3],"6":[4],"(PCAT6)":[5],"is":[6,13,38],"a":[7,25,81,130,185,193,213],"long":[8],"intergenic":[9],"noncoding":[10],"RNA":[11],"that":[12,110,120,181,209],"involved":[14],"in":[15,31,47,60,73,84,87,99,114,121,137,149],"the":[16,55,94,104,155,162,173],"progression":[17],"of":[18,58,69,83,97,157,176,188,220],"prostate":[19],"and":[20,28,43,63,80,86,103,129,136,145,159,200,217],"lung":[21,34],"cancer,":[22],"acting":[23],"as":[24,184],"potential":[26],"diagnostic":[27],"prognostic":[29,215],"biomarker":[30],"nonsmall":[32],"cell":[33,143,147,198],"cancer.":[35,49,151,222],"However,":[36],"little":[37],"known":[39],"about":[40],"PCAT6":[41,59,70,98,111,141,153,182,210],"expression":[42,68,190],"its":[44,64],"clinical":[45,56,127],"significance":[46,57],"colon":[48,61,74,100,115,150,203,221],"Here,":[50],"we":[51],"aimed":[52],"to":[53,92,202],"investigate":[54,93],"cancer":[62,75,101,116,204],"underlying":[65,105],"mechanism.":[66],"The":[67],"was":[71,90,112],"analyzed":[72],"tissues":[76,117],"using":[77],"public":[78],"databases,":[79],"series":[82],"vitro":[85,135],"vivo":[88,138],"experiments":[89,139],"performed":[91],"biological":[95],"functions":[96],"cells":[102],"mechanisms.":[106],"Our":[107,178],"results":[108],"demonstrated":[109],"upregulated":[113],"compared":[118],"with":[119,125,165,195],"noncancerous":[122],"tissues,":[123],"correlating":[124],"poorer":[126],"stages":[128],"worse":[131],"survival":[132],"status.":[133],"In":[134],"illustrated":[140],"promoted":[142],"growth":[144],"inhibited":[146],"apoptosis":[148,163,199],"Mechanistically,":[152],"enhanced":[154],"coenrichment":[156],"EZH2":[158],"H3K4me3":[160],"at":[161],"repressor":[164],"caspase":[166],"recruitment":[167],"domain":[168],"(ARC)":[169],"genomic":[170],"region,":[171],"promoting":[172],"transcriptional":[174],"activity":[175],"ARC.":[177],"data":[179],"highlighted":[180],"acts":[183],"key":[186],"activator":[187],"ARC":[189],"by":[191],"forming":[192],"complex":[194],"EZH2,":[196],"inhibiting":[197],"contributing":[201],"progression.":[205],"These":[206],"findings":[207],"elucidated":[208],"may":[211],"be":[212],"novel":[214],"predictor":[216],"therapeutic":[218],"target":[219]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":10}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-01-01T00:00:00"}