{"id":"https://openalex.org/W2905463189","doi":"https://doi.org/10.1152/ajprenal.00130.2018","title":"\u201cI don\u2019t get no respect\u201d: the role of chloride in acute kidney injury","display_name":"\u201cI don\u2019t get no respect\u201d: the role of chloride in acute kidney injury","publication_year":2018,"publication_date":"2018-12-12","ids":{"openalex":"https://openalex.org/W2905463189","doi":"https://doi.org/10.1152/ajprenal.00130.2018","mag":"2905463189","pmid":"https://pubmed.ncbi.nlm.nih.gov/30539650"},"language":"en","primary_location":{"id":"doi:10.1152/ajprenal.00130.2018","doi":"https://doi.org/10.1152/ajprenal.00130.2018","is_oa":true,"landing_page_url":"https://doi.org/10.1152/ajprenal.00130.2018","pdf_url":"https://journals.physiology.org/doi/pdf/10.1152/ajprenal.00130.2018","source":{"id":"https://openalex.org/S200780590","display_name":"American Journal of Physiology-Renal Physiology","issn_l":"1522-1466","issn":["1522-1466","1931-857X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Renal Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://journals.physiology.org/doi/pdf/10.1152/ajprenal.00130.2018","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070372137","display_name":"Joshua L. Rein","orcid":"https://orcid.org/0000-0001-6384-9528","observed_orcids":["https://orcid.org/0000-0001-6384-9528"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua L. Rein","raw_affiliation_strings":["Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067577526","display_name":"Steven G. Coca","orcid":"https://orcid.org/0000-0002-0928-9168","observed_orcids":["https://orcid.org/0000-0002-0928-9168"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Steven G. Coca","raw_affiliation_strings":["Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York","institution_ids":["https://openalex.org/I98704320"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5067577526"],"corresponding_institution_ids":["https://openalex.org/I98704320"],"apc_list":null,"apc_paid":null,"fwci":4.5818,"has_fulltext":true,"cited_by_count":101,"citation_normalized_percentile":{"value":0.9529659,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"316","issue":"3","first_page":"F587","last_page":"F605"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12429","display_name":"Chemotherapy-induced organ toxicity mitigation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-kidney-injury","display_name":"acute kidney injury","score":0.9940000176429749},{"id":"https://openalex.org/keywords/chloride","display_name":"chloride","score":0.8479999899864197},{"id":"https://openalex.org/keywords/serum-chloride","display_name":"serum chloride","score":0.7760000228881836},{"id":"https://openalex.org/keywords/intravenous-fluids","display_name":"intravenous fluids","score":0.8889999985694885},{"id":"https://openalex.org/keywords/normal-saline","display_name":"normal saline","score":0.824999988079071},{"id":"https://openalex.org/keywords/balanced-crystalloids","display_name":"balanced crystalloids","score":0.7960000038146973},{"id":"https://openalex.org/keywords/renal-blood-flow","display_name":"renal blood flow","score":0.7429999709129333},{"id":"https://openalex.org/keywords/glomerular-filtration-rate","display_name":"glomerular filtration rate","score":1.0},{"id":"https://openalex.org/keywords/tubuloglomerular-feedback","display_name":"tubuloglomerular feedback","score":1.0},{"id":"https://openalex.org/keywords/renal-tubular-injury","display_name":"renal tubular injury","score":0.9890000224113464},{"id":"https://openalex.org/keywords/chronic-kidney-disease-progression","display_name":"chronic kidney disease progression","score":0.6919999718666077},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.33500000834465027}],"concepts":[{"id":"https://openalex.org/C2780472472","wikidata":"https://www.wikidata.org/wiki/Q424337","display_name":"Acute kidney injury","level":2,"score":0.8002068400382996},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7641779184341431},{"id":"https://openalex.org/C2780541033","wikidata":"https://www.wikidata.org/wiki/Q432392","display_name":"Serum chloride","level":3,"score":0.727914035320282},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.6029897928237915},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5425740480422974},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.509458601474762},{"id":"https://openalex.org/C142225936","wikidata":"https://www.wikidata.org/wiki/Q1129139","display_name":"Renal blood flow","level":3,"score":0.49930572509765625},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.49386268854141235},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4668145179748535},{"id":"https://openalex.org/C54847362","wikidata":"https://www.wikidata.org/wiki/Q177635","display_name":"Nephrology","level":2,"score":0.42611053586006165},{"id":"https://openalex.org/C2778695967","wikidata":"https://www.wikidata.org/wiki/Q44791900","display_name":"Chloride","level":2,"score":0.3503762483596802},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3243156671524048},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.08044511079788208},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002712","descriptor_name":"Chlorides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002712","descriptor_name":"Chlorides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002712","descriptor_name":"Chlorides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005919","descriptor_name":"Glomerular Filtration Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005919","descriptor_name":"Glomerular Filtration Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005919","descriptor_name":"Glomerular Filtration Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1152/ajprenal.00130.2018","doi":"https://doi.org/10.1152/ajprenal.00130.2018","is_oa":true,"landing_page_url":"https://doi.org/10.1152/ajprenal.00130.2018","pdf_url":"https://journals.physiology.org/doi/pdf/10.1152/ajprenal.00130.2018","source":{"id":"https://openalex.org/S200780590","display_name":"American Journal of Physiology-Renal Physiology","issn_l":"1522-1466","issn":["1522-1466","1931-857X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Renal Physiology","raw_type":"journal-article"},{"id":"pmid:30539650","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30539650","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of physiology. Renal physiology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5991610","doi":null,"is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6459301","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6459301","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6459301","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Am J Physiol Renal Physiol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1152/ajprenal.00130.2018","doi":"https://doi.org/10.1152/ajprenal.00130.2018","is_oa":true,"landing_page_url":"https://doi.org/10.1152/ajprenal.00130.2018","pdf_url":"https://journals.physiology.org/doi/pdf/10.1152/ajprenal.00130.2018","source":{"id":"https://openalex.org/S200780590","display_name":"American Journal of Physiology-Renal Physiology","issn_l":"1522-1466","issn":["1522-1466","1931-857X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Renal Physiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9789000153541565,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8799999952316284,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G258014889","display_name":null,"funder_award_id":"R25-DK101390","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2653473004","display_name":null,"funder_award_id":"U01DK106962","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3101778425","display_name":null,"funder_award_id":"T32DK007757","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G738790256","display_name":null,"funder_award_id":"U01DK082185","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G756854901","display_name":null,"funder_award_id":"R01 HL-085757","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7892070945","display_name":null,"funder_award_id":"R01HL085757","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000864410","display_name":"Summer Undergraduate Program in Emory Renal Research (SUPERR)","funder_award_id":"5r25dk101390-12","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G910230010","display_name":null,"funder_award_id":"R01DK096549","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2905463189.pdf","grobid_xml":"https://content.openalex.org/works/W2905463189.grobid-xml"},"referenced_works_count":265,"referenced_works":["https://openalex.org/W95432225","https://openalex.org/W182172222","https://openalex.org/W182398977","https://openalex.org/W1075135446","https://openalex.org/W1514274957","https://openalex.org/W1543839649","https://openalex.org/W1549450492","https://openalex.org/W1564079474","https://openalex.org/W1592232168","https://openalex.org/W1747865589","https://openalex.org/W1818001455","https://openalex.org/W1853219683","https://openalex.org/W1906809771","https://openalex.org/W1933891932","https://openalex.org/W1964781343","https://openalex.org/W1965138935","https://openalex.org/W1966186276","https://openalex.org/W1966944404","https://openalex.org/W1967615754","https://openalex.org/W1970486445","https://openalex.org/W1970873266","https://openalex.org/W1971171800","https://openalex.org/W1971534148","https://openalex.org/W1972449270","https://openalex.org/W1973124173","https://openalex.org/W1976201501","https://openalex.org/W1977146248","https://openalex.org/W1977626956","https://openalex.org/W1978224292","https://openalex.org/W1978575426","https://openalex.org/W1978603848","https://openalex.org/W1978873692","https://openalex.org/W1982155303","https://openalex.org/W1986629760","https://openalex.org/W1987303342","https://openalex.org/W1987421575","https://openalex.org/W1988542327","https://openalex.org/W1992671417","https://openalex.org/W1993674429","https://openalex.org/W1994355238","https://openalex.org/W1995514808","https://openalex.org/W1996224470","https://openalex.org/W1996413867","https://openalex.org/W1997161718","https://openalex.org/W1998714019","https://openalex.org/W1998750699","https://openalex.org/W2000865477","https://openalex.org/W2001356046","https://openalex.org/W2001660722","https://openalex.org/W2002770567","https://openalex.org/W2004247306","https://openalex.org/W2005522538","https://openalex.org/W2006453934","https://openalex.org/W2008702734","https://openalex.org/W2012646204","https://openalex.org/W2014698393","https://openalex.org/W2016230143","https://openalex.org/W2017917339","https://openalex.org/W2019394579","https://openalex.org/W2020449386","https://openalex.org/W2022585333","https://openalex.org/W2023000258","https://openalex.org/W2024509859","https://openalex.org/W2025033378","https://openalex.org/W2028701043","https://openalex.org/W2030383086","https://openalex.org/W2030813446","https://openalex.org/W2031179250","https://openalex.org/W2031495307","https://openalex.org/W2031501562","https://openalex.org/W2033403165","https://openalex.org/W2040732119","https://openalex.org/W2042764875","https://openalex.org/W2042959282","https://openalex.org/W2046997377","https://openalex.org/W2049411416","https://openalex.org/W2050875396","https://openalex.org/W2051267775","https://openalex.org/W2052033567","https://openalex.org/W2053711328","https://openalex.org/W2056983547","https://openalex.org/W2057351603","https://openalex.org/W2060183868","https://openalex.org/W2061042844","https://openalex.org/W2062208018","https://openalex.org/W2064143634","https://openalex.org/W2064498648","https://openalex.org/W2065862067","https://openalex.org/W2066166091","https://openalex.org/W2066337868","https://openalex.org/W2066906091","https://openalex.org/W2067396617","https://openalex.org/W2068909898","https://openalex.org/W2070989396","https://openalex.org/W2075231275","https://openalex.org/W2077173768","https://openalex.org/W2077911879","https://openalex.org/W2077944368","https://openalex.org/W2077965692","https://openalex.org/W2078202625","https://openalex.org/W2078902399","https://openalex.org/W2079079821","https://openalex.org/W2079551427","https://openalex.org/W2081010513","https://openalex.org/W2084253247","https://openalex.org/W2085183064","https://openalex.org/W2085591802","https://openalex.org/W2086945610","https://openalex.org/W2088787525","https://openalex.org/W2089271682","https://openalex.org/W2090155528","https://openalex.org/W2091454527","https://openalex.org/W2091776886","https://openalex.org/W2093253335","https://openalex.org/W2093619119","https://openalex.org/W2095015797","https://openalex.org/W2095167834","https://openalex.org/W2096652787","https://openalex.org/W2097697450","https://openalex.org/W2098302088","https://openalex.org/W2098441893","https://openalex.org/W2098939489","https://openalex.org/W2099645092","https://openalex.org/W2100268343","https://openalex.org/W2102606565","https://openalex.org/W2103341354","https://openalex.org/W2106835658","https://openalex.org/W2109040135","https://openalex.org/W2112180939","https://openalex.org/W2113226929","https://openalex.org/W2113754691","https://openalex.org/W2115781115","https://openalex.org/W2117005662","https://openalex.org/W2117376136","https://openalex.org/W2118981009","https://openalex.org/W2119129344","https://openalex.org/W2119226572","https://openalex.org/W2119815555","https://openalex.org/W2122715588","https://openalex.org/W2123729305","https://openalex.org/W2124472004","https://openalex.org/W2126154188","https://openalex.org/W2127065370","https://openalex.org/W2128116806","https://openalex.org/W2131711857","https://openalex.org/W2132602567","https://openalex.org/W2132840361","https://openalex.org/W2135394966","https://openalex.org/W2136616875","https://openalex.org/W2139645437","https://openalex.org/W2141993530","https://openalex.org/W2142045542","https://openalex.org/W2142057837","https://openalex.org/W2146920291","https://openalex.org/W2154078412","https://openalex.org/W2154100497","https://openalex.org/W2155164384","https://openalex.org/W2158012228","https://openalex.org/W2159061813","https://openalex.org/W2159102305","https://openalex.org/W2161515130","https://openalex.org/W2162205081","https://openalex.org/W2164507457","https://openalex.org/W2165995565","https://openalex.org/W2167594720","https://openalex.org/W2167807923","https://openalex.org/W2168342166","https://openalex.org/W2169230483","https://openalex.org/W2169664787","https://openalex.org/W2178033401","https://openalex.org/W2208030318","https://openalex.org/W2221150482","https://openalex.org/W2229886140","https://openalex.org/W2230764365","https://openalex.org/W2245308845","https://openalex.org/W2253006731","https://openalex.org/W2271670503","https://openalex.org/W2290058439","https://openalex.org/W2299554199","https://openalex.org/W2316092613","https://openalex.org/W2325438096","https://openalex.org/W2330148983","https://openalex.org/W2330351814","https://openalex.org/W2332768694","https://openalex.org/W2333696067","https://openalex.org/W2335242415","https://openalex.org/W2336296071","https://openalex.org/W2337241244","https://openalex.org/W2339844797","https://openalex.org/W2340383377","https://openalex.org/W2340504287","https://openalex.org/W2341922339","https://openalex.org/W2343652732","https://openalex.org/W2395352628","https://openalex.org/W2397166689","https://openalex.org/W2408943659","https://openalex.org/W2412104809","https://openalex.org/W2413380494","https://openalex.org/W2414291215","https://openalex.org/W2415232682","https://openalex.org/W2415520457","https://openalex.org/W2416078138","https://openalex.org/W2416257219","https://openalex.org/W2416307238","https://openalex.org/W2417904682","https://openalex.org/W2418357434","https://openalex.org/W2418612502","https://openalex.org/W2420721790","https://openalex.org/W2430340792","https://openalex.org/W2432150929","https://openalex.org/W2434260882","https://openalex.org/W2437099147","https://openalex.org/W2443236653","https://openalex.org/W2460205765","https://openalex.org/W2462649855","https://openalex.org/W2463308832","https://openalex.org/W2465128455","https://openalex.org/W2465205863","https://openalex.org/W2469372311","https://openalex.org/W2472740902","https://openalex.org/W2477146316","https://openalex.org/W2512055250","https://openalex.org/W2512539392","https://openalex.org/W2526229549","https://openalex.org/W2529785579","https://openalex.org/W2548301463","https://openalex.org/W2581605534","https://openalex.org/W2587455962","https://openalex.org/W2597926971","https://openalex.org/W2600542038","https://openalex.org/W2622029774","https://openalex.org/W2626731045","https://openalex.org/W2735211008","https://openalex.org/W2737417474","https://openalex.org/W2737610930","https://openalex.org/W2752632042","https://openalex.org/W2760025487","https://openalex.org/W2762871364","https://openalex.org/W2767839334","https://openalex.org/W2770474763","https://openalex.org/W2771774936","https://openalex.org/W2774529359","https://openalex.org/W2775743887","https://openalex.org/W2781063914","https://openalex.org/W2786979840","https://openalex.org/W2790158735","https://openalex.org/W2795168521","https://openalex.org/W2795340196","https://openalex.org/W2799973924","https://openalex.org/W2803558610","https://openalex.org/W2886054575","https://openalex.org/W2886921111","https://openalex.org/W2920281899","https://openalex.org/W2952762910","https://openalex.org/W3045454797","https://openalex.org/W4211094492","https://openalex.org/W4236073677","https://openalex.org/W4239557229","https://openalex.org/W4240800601","https://openalex.org/W4241014756","https://openalex.org/W4245235758","https://openalex.org/W4246757817","https://openalex.org/W4248153712","https://openalex.org/W4253954955","https://openalex.org/W4387760500"],"related_works":["https://openalex.org/W2326933351","https://openalex.org/W2416005624","https://openalex.org/W2999297870","https://openalex.org/W2005120007","https://openalex.org/W23151206","https://openalex.org/W2883957337","https://openalex.org/W3142512143","https://openalex.org/W2955415818","https://openalex.org/W3021350469","https://openalex.org/W4387409017"],"abstract_inverted_index":{"Acute":[0],"kidney":[1,28],"injury":[2],"(AKI)":[3],"is":[4,18,145,156,163],"a":[5,164],"major":[6],"public":[7],"health":[8],"problem":[9],"that":[10,73],"complicates":[11],"10-40%":[12],"of":[13,24,38,46,80,90,106,126,134,159,199],"hospital":[14],"admissions.":[15],"Importantly,":[16],"AKI":[17,186],"independently":[19],"associated":[20,86],"with":[21,62,87,184],"increased":[22,36,88],"risk":[23,37,89,176,198],"progression":[25],"to":[26,130,195],"chronic":[27],"disease,":[29,32],"end-stage":[30],"renal":[31,101,110],"cardiovascular":[33],"events,":[34],"and":[35,40,65,83,93,118,142,150,171,182],"in-hospital":[39],"long-term":[41],"mortality.":[42,94],"The":[43],"chloride":[44,77,107,132,140,161],"content":[45,133],"intravenous":[47,135],"fluid":[48],"has":[49],"garnered":[50],"much":[51],"attention":[52],"over":[53],"the":[54,99,104,124,131,153,197],"last":[55],"decade,":[56],"as":[57,59,121,123],"well":[58,122],"its":[60],"association":[61],"excess":[63],"use":[64],"adverse":[66],"outcomes,":[67],"including":[68],"AKI.":[69,143,178,200],"Numerous":[70],"studies":[71],"show":[72],"changes":[74,137],"in":[75,108,138,147,173],"serum":[76,81,139],"concentration,":[78,141],"independent":[79],"sodium":[82],"bicarbonate,":[84],"are":[85],"AKI,":[91],"morbidity,":[92],"This":[95],"comprehensive":[96],"review":[97],"details":[98],"complex":[100],"physiology":[102,149],"regarding":[103],"role":[105],"regulating":[109],"blood":[111],"flow,":[112],"glomerular":[113],"filtration":[114],"rate,":[115],"tubuloglomerular":[116],"feedback,":[117],"tubular":[119],"injury,":[120],"findings":[125],"clinical":[127],"research":[128],"related":[129],"fluids,":[136],"Chloride":[144],"underappreciated":[146],"both":[148],"pathophysiology.":[151],"Although":[152],"exact":[154],"mechanism":[155],"debated,":[157],"avoidance":[158],"excessive":[160],"administration":[162],"reasonable":[165],"treatment":[166],"option":[167],"for":[168,177],"all":[169],"patients":[170,181],"especially":[172],"those":[174,183],"at":[175],"Therefore,":[179],"high-risk":[180],"\"incipient\"":[185],"should":[187],"receive":[188],"balanced":[189],"solutions":[190],"rather":[191],"than":[192],"normal":[193],"saline":[194],"minimize":[196]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":18},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":3}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}