{"id":"https://openalex.org/W2905108752","doi":"https://doi.org/10.1097/acm.0000000000002542","title":"The Yale Center for Biomedical Innovation and Technology (CBIT): One Model to Accelerate Impact From Academic Health Care Innovation","display_name":"The Yale Center for Biomedical Innovation and Technology (CBIT): One Model to Accelerate Impact From Academic Health Care Innovation","publication_year":2018,"publication_date":"2018-12-05","ids":{"openalex":"https://openalex.org/W2905108752","doi":"https://doi.org/10.1097/acm.0000000000002542","mag":"2905108752","pmid":"https://pubmed.ncbi.nlm.nih.gov/30520807"},"language":"en","primary_location":{"id":"doi:10.1097/acm.0000000000002542","doi":"https://doi.org/10.1097/acm.0000000000002542","is_oa":false,"landing_page_url":"https://doi.org/10.1097/acm.0000000000002542","pdf_url":null,"source":{"id":"https://openalex.org/S19793444","display_name":"Academic Medicine","issn_l":"1040-2446","issn":["1040-2446","1938-808X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Academic Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020316811","display_name":"Alyssa L. Siefert","orcid":"https://orcid.org/0000-0002-3944-3373","observed_orcids":["https://orcid.org/0000-0002-3944-3373"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alyssa L. Siefert","raw_affiliation_strings":["is engineering director, Yale Center for Biomedical Innovation and Technology (CBIT), and biomedical engineering lecturer, Yale University, New Haven, Connecticut","Ethical approval: Reported as not applicable","Other disclosures: None reported"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"is engineering director, Yale Center for Biomedical Innovation and Technology (CBIT), and biomedical engineering lecturer, Yale University, New Haven, Connecticut","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Ethical approval: Reported as not applicable","institution_ids":[]},{"raw_affiliation_string":"Other disclosures: None reported","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066282733","display_name":"Malgorzata S. Cartiera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I4210117499","display_name":"Yale New Haven Health System","ror":"https://ror.org/01s1hsq14","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210117499"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Malgorzata S. Cartiera","raw_affiliation_strings":["is investment and innovation director, Yale CBIT and Center for Health Innovation, Yale New Haven Health System, New Haven, Connecticut","Ethical approval: Reported as not applicable","Other disclosures: None reported"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"is investment and innovation director, Yale CBIT and Center for Health Innovation, Yale New Haven Health System, New Haven, Connecticut","institution_ids":["https://openalex.org/I32971472","https://openalex.org/I4210117499"]},{"raw_affiliation_string":"Ethical approval: Reported as not applicable","institution_ids":[]},{"raw_affiliation_string":"Other disclosures: None reported","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037958982","display_name":"Ayesha N. Khalid","orcid":"https://orcid.org/0000-0001-6637-9904","observed_orcids":["https://orcid.org/0000-0001-6637-9904"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ayesha N. Khalid","raw_affiliation_strings":["is clinical director, Yale CBIT, New Haven, Connecticut, and clinical instructor, Harvard Medical School, Boston, Massachusetts","Ethical approval: Reported as not applicable","Other disclosures: None reported"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"is clinical director, Yale CBIT, New Haven, Connecticut, and clinical instructor, Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I32971472"]},{"raw_affiliation_string":"Ethical approval: Reported as not applicable","institution_ids":[]},{"raw_affiliation_string":"Other disclosures: None reported","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5095860876","display_name":"Michelle C. Nantel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michelle C. Nantel","raw_affiliation_strings":["is program coordinator, Yale CBIT, New Haven, Connecticut","Ethical approval: Reported as not applicable","Other disclosures: None reported"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"is program coordinator, Yale CBIT, New Haven, Connecticut","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Ethical approval: Reported as not applicable","institution_ids":[]},{"raw_affiliation_string":"Other disclosures: None reported","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081694869","display_name":"Christopher R. Loose","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher R. Loose","raw_affiliation_strings":["is coexecutive director, Yale CBIT, New Haven, Connecticut, and chief scientific officer, Frequency Therapeutics, Cambridge, Massachusetts","Ethical approval: Reported as not applicable","Other disclosures: None reported"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"is coexecutive director, Yale CBIT, New Haven, Connecticut, and chief scientific officer, Frequency Therapeutics, Cambridge, Massachusetts","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Ethical approval: Reported as not applicable","institution_ids":[]},{"raw_affiliation_string":"Other disclosures: None reported","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055947197","display_name":"Peter G. Schulam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter G. Schulam","raw_affiliation_strings":["is cofounder, Yale CBIT, chair of urology, Yale School of Medicine, and faculty director, Tsai Center for Innovative Thinking, Yale University, New Haven, Connecticut","Ethical approval: Reported as not applicable","Other disclosures: None reported"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"is cofounder, Yale CBIT, chair of urology, Yale School of Medicine, and faculty director, Tsai Center for Innovative Thinking, Yale University, New Haven, Connecticut","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Ethical approval: Reported as not applicable","institution_ids":[]},{"raw_affiliation_string":"Other disclosures: None reported","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012106344","display_name":"W. Mark Saltzman","orcid":"https://orcid.org/0000-0002-2163-549X","observed_orcids":["https://orcid.org/0000-0002-2163-549X"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Mark Saltzman","raw_affiliation_strings":["is cofounder, Yale CBIT, and Goizueta Foundation Professor of Biomedical and Chemical Engineering, Yale University, New Haven, Connecticut","Ethical approval: Reported as not applicable","Other disclosures: None reported"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"is cofounder, Yale CBIT, and Goizueta Foundation Professor of Biomedical and Chemical Engineering, Yale University, New Haven, Connecticut","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Ethical approval: Reported as not applicable","institution_ids":[]},{"raw_affiliation_string":"Other disclosures: None reported","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025505901","display_name":"Michael K. Dempsey","orcid":"https://orcid.org/0000-0002-4716-1931","observed_orcids":["https://orcid.org/0000-0002-4716-1931"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael K. Dempsey","raw_affiliation_strings":["is coexecutive director, Yale CBIT, New Haven, Connecticut, and entrepreneur-in-residence, Consortia for Improving Medicine with Innovation & Technology (CIMIT), Boston, Massachusetts","Ethical approval: Reported as not applicable","Other disclosures: None reported","Previous presentations: The health care innovation framework was developed by Michael Dempsey, John Collins, John Parrish, Steve Schachter, and others at the Consortia for Improving Medicine with Innovation & Technology (CIMIT), used with permission","should be addressed to Michael K. Dempsey, 310 Cedar St., BML 238B, New Haven, CT 06501"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"is coexecutive director, Yale CBIT, New Haven, Connecticut, and entrepreneur-in-residence, Consortia for Improving Medicine with Innovation & Technology (CIMIT), Boston, Massachusetts","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Ethical approval: Reported as not applicable","institution_ids":[]},{"raw_affiliation_string":"Other disclosures: None reported","institution_ids":[]},{"raw_affiliation_string":"Previous presentations: The health care innovation framework was developed by Michael Dempsey, John Collins, John Parrish, Steve Schachter, and others at the Consortia for Improving Medicine with Innovation & Technology (CIMIT), used with permission","institution_ids":[]},{"raw_affiliation_string":"should be addressed to Michael K. Dempsey, 310 Cedar St., BML 238B, New Haven, CT 06501","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5025505901"],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":null,"apc_paid":null,"fwci":3.0928,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.91553943,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"94","issue":"4","first_page":"528","last_page":"534"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12168","display_name":"Health and Medical Research Impacts","score":0.7343999743461609,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12168","display_name":"Health and Medical Research Impacts","score":0.7343999743461609,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13280","display_name":"Biomedical and Engineering Education","score":0.2295999974012375,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14293","display_name":"Biotechnology and Related Fields","score":0.007199999876320362,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/translational-research","display_name":"translational research","score":0.9120000004768372},{"id":"https://openalex.org/keywords/innovation-cycle","display_name":"innovation cycle","score":0.35199999809265137},{"id":"https://openalex.org/keywords/mentoring","display_name":"mentoring","score":0.8220000267028809},{"id":"https://openalex.org/keywords/commercialization","display_name":"commercialization","score":0.5849999785423279},{"id":"https://openalex.org/keywords/innovation-ecosystems","display_name":"innovation ecosystems","score":0.375}],"concepts":[{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.6267715692520142},{"id":"https://openalex.org/C2776535583","wikidata":"https://www.wikidata.org/wiki/Q967647","display_name":"Mentorship","level":2,"score":0.4788122773170471},{"id":"https://openalex.org/C2780222150","wikidata":"https://www.wikidata.org/wiki/Q2896785","display_name":"Academic detailing","level":3,"score":0.41032469272613525},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.40748926997184753},{"id":"https://openalex.org/C509550671","wikidata":"https://www.wikidata.org/wiki/Q126945","display_name":"Medical education","level":1,"score":0.3379160165786743},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3376064896583557},{"id":"https://openalex.org/C39549134","wikidata":"https://www.wikidata.org/wiki/Q133080","display_name":"Public relations","level":1,"score":0.3221225142478943},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.24074357748031616},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.16143923997879028},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.14123883843421936}],"mesh":[{"descriptor_ui":"D000076363","descriptor_name":"Academic Success","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020811","descriptor_name":"Biomedical Technology","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":true},{"descriptor_ui":"D020811","descriptor_name":"Biomedical Technology","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false},{"descriptor_ui":"D062069","descriptor_name":"Inventions","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/acm.0000000000002542","doi":"https://doi.org/10.1097/acm.0000000000002542","is_oa":false,"landing_page_url":"https://doi.org/10.1097/acm.0000000000002542","pdf_url":null,"source":{"id":"https://openalex.org/S19793444","display_name":"Academic Medicine","issn_l":"1040-2446","issn":["1040-2446","1938-808X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Academic Medicine","raw_type":"journal-article"},{"id":"pmid:30520807","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30520807","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Academic medicine : journal of the Association of American Medical Colleges","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W2003242365","https://openalex.org/W2018492385","https://openalex.org/W2028056767","https://openalex.org/W2052998146","https://openalex.org/W2054163850","https://openalex.org/W2095569769","https://openalex.org/W2115146414","https://openalex.org/W2152158712","https://openalex.org/W2168510578","https://openalex.org/W2487804550","https://openalex.org/W2525449058","https://openalex.org/W2600891110","https://openalex.org/W6722373841"],"related_works":["https://openalex.org/W2743837697","https://openalex.org/W6924821232","https://openalex.org/W3162544779","https://openalex.org/W2525449058","https://openalex.org/W3199396315","https://openalex.org/W2563901225","https://openalex.org/W3127006282","https://openalex.org/W1973749728","https://openalex.org/W2744189421","https://openalex.org/W4245594076"],"abstract_inverted_index":{"The":[0,95,212],"process":[1],"of":[2,43,91,179,188,190,200,204,226,236],"translating":[3],"academic":[4,39,205],"biomedical":[5,227],"advances":[6],"into":[7],"clinical":[8,47,155,208],"care":[9,24,48,64,93,100,134,164],"improvements":[10],"is":[11,216],"difficult,":[12],"risky,":[13],"expensive,":[14],"and":[15,37,78,87,103,115,130,152,161,177,185,210,229,234],"poorly":[16],"understood.":[17],"Notably,":[18],"many":[19,38],"clinicians":[20],"who":[21,60,68],"identify":[22,62],"health":[23,63,92,99,133,163],"problems":[25,65],"do":[26],"not":[27],"have":[28,170,182],"the":[29,35,72,89,202,224,232],"time":[30],"or":[31,149],"expertise":[32,52],"to":[33,49,57,85,117,141,173,218,222],"solve":[34,70],"problems,":[36],"researchers":[40],"are":[41],"unaware":[42],"important":[44],"gaps":[45],"in":[46,83],"which":[50,111],"their":[51],"may":[53],"apply.Recognizing":[54],"an":[55,138],"opportunity":[56],"connect":[58],"people":[59,129],"can":[61,69],"with":[66],"those":[67,180],"them,":[71],"Yale":[73,109,123,145,195],"Center":[74],"for":[75,158,175],"Biomedical":[76],"Innovation":[77],"Technology":[79],"(CBIT)":[80],"was":[81],"established":[82,131],"2014":[84],"educate":[86],"enhance":[88],"impact":[90,203],"innovators.":[94],"authors":[96,193],"review":[97],"other":[98],"innovation":[101,135,228],"centers":[102],"describe":[104],"best":[105],"practices":[106],"borrowed":[107],"by":[108],"CBIT,":[110],"tailored":[112],"its":[113,118],"activities":[114],"approach":[116],"unique":[119],"ecosystem.In":[120],"four":[121],"years,":[122],"CBIT":[124,146,174,196],"has":[125,147],"affected":[126],"over":[127],"3,000":[128],"a":[132,220],"cycle":[136],"as":[137,197],"efficient":[139],"strategy":[140,215],"guide":[142],"translational":[143],"research.":[144],"created":[148],"supported":[150],"graduate":[151],"undergraduate":[153],"courses,":[154],"immersion":[156],"programs":[157],"industry":[159],"partners,":[160],"large":[162],"hackathon":[165],"events.":[166],"Over":[167],"200":[168],"projects":[169,181],"been":[171,183],"submitted":[172],"mentorship,":[176],"some":[178],"commercialized":[184],"raised":[186],"millions":[187],"dollars":[189],"follow-on":[191],"funding.The":[192],"present":[194],"one":[198],"model":[199],"accelerating":[201],"medicine":[206],"on":[207],"practice":[209],"outcomes.":[211],"project":[213],"advising":[214],"intended":[217],"be":[219],"template":[221],"maximize":[223],"efficiency":[225],"ultimately":[230],"improve":[231],"outcomes":[233],"experiences":[235],"future":[237],"patients.":[238]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-12-22T00:00:00"}