{"id":"https://openalex.org/W2904874692","doi":"https://doi.org/10.1016/j.hbpd.2018.12.002","title":"Novel non-invasive score to predict cirrhosis in the era of hepatitis C elimination: A population study of ex-substance users in Singapore","display_name":"Novel non-invasive score to predict cirrhosis in the era of hepatitis C elimination: A population study of ex-substance users in Singapore","publication_year":2018,"publication_date":"2018-12-06","ids":{"openalex":"https://openalex.org/W2904874692","doi":"https://doi.org/10.1016/j.hbpd.2018.12.002","mag":"2904874692","pmid":"https://pubmed.ncbi.nlm.nih.gov/30558838"},"language":"en","primary_location":{"id":"doi:10.1016/j.hbpd.2018.12.002","doi":"https://doi.org/10.1016/j.hbpd.2018.12.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.hbpd.2018.12.002","pdf_url":null,"source":{"id":"https://openalex.org/S2483261043","display_name":"Hepatobiliary & pancreatic diseases international","issn_l":"2352-9377","issn":["2352-9377","1499-3872"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatobiliary & Pancreatic Diseases International","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100458080","display_name":"Yue Zhao","orcid":"https://orcid.org/0000-0002-6466-6202","observed_orcids":["https://orcid.org/0000-0002-6466-6202"]},"institutions":[{"id":"https://openalex.org/I157582758","display_name":"SingHealth","ror":"https://ror.org/04me94w47","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I157582758"]},{"id":"https://openalex.org/I2802225915","display_name":"Changi General Hospital","ror":"https://ror.org/02q854y08","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802225915"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Yue Zhao","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore","institution_ids":["https://openalex.org/I157582758","https://openalex.org/I2802225915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065195676","display_name":"Prem Harichander Thurairajah","orcid":"https://orcid.org/0000-0002-9411-1523","observed_orcids":["https://orcid.org/0000-0002-9411-1523"]},"institutions":[{"id":"https://openalex.org/I157582758","display_name":"SingHealth","ror":"https://ror.org/04me94w47","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I157582758"]},{"id":"https://openalex.org/I2802225915","display_name":"Changi General Hospital","ror":"https://ror.org/02q854y08","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802225915"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Prem Harichander Thurairajah","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore","institution_ids":["https://openalex.org/I157582758","https://openalex.org/I2802225915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013629920","display_name":"Rahul Kumar","orcid":"https://orcid.org/0000-0002-5092-4821","observed_orcids":["https://orcid.org/0000-0002-5092-4821"]},"institutions":[{"id":"https://openalex.org/I157582758","display_name":"SingHealth","ror":"https://ror.org/04me94w47","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I157582758"]},{"id":"https://openalex.org/I2802225915","display_name":"Changi General Hospital","ror":"https://ror.org/02q854y08","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802225915"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Rahul Kumar","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore","institution_ids":["https://openalex.org/I157582758","https://openalex.org/I2802225915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064387232","display_name":"Jessica Juliana Tan","orcid":"https://orcid.org/0000-0002-4249-5975","observed_orcids":["https://orcid.org/0000-0002-4249-5975"]},"institutions":[{"id":"https://openalex.org/I157582758","display_name":"SingHealth","ror":"https://ror.org/04me94w47","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I157582758"]},{"id":"https://openalex.org/I2802225915","display_name":"Changi General Hospital","ror":"https://ror.org/02q854y08","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802225915"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Jessica Tan","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore","institution_ids":["https://openalex.org/I157582758","https://openalex.org/I2802225915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034213116","display_name":"Eng Kiong Teo","orcid":"https://orcid.org/0000-0001-5095-6527","observed_orcids":["https://orcid.org/0000-0001-5095-6527"]},"institutions":[{"id":"https://openalex.org/I157582758","display_name":"SingHealth","ror":"https://ror.org/04me94w47","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I157582758"]},{"id":"https://openalex.org/I2802225915","display_name":"Changi General Hospital","ror":"https://ror.org/02q854y08","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802225915"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Eng Kiong Teo","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore","institution_ids":["https://openalex.org/I157582758","https://openalex.org/I2802225915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052217593","display_name":"John Chen Hsiang","orcid":"https://orcid.org/0000-0002-7124-6396","observed_orcids":["https://orcid.org/0000-0002-7124-6396"]},"institutions":[{"id":"https://openalex.org/I157582758","display_name":"SingHealth","ror":"https://ror.org/04me94w47","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I157582758"]},{"id":"https://openalex.org/I2802225915","display_name":"Changi General Hospital","ror":"https://ror.org/02q854y08","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802225915"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"John Chen Hsiang","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore. Electronic address: jchsiang@gmail.com","Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore. Electronic address: jchsiang@gmail.com","institution_ids":["https://openalex.org/I157582758","https://openalex.org/I2802225915"]},{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, Changi General Hospital, Singhealth, Singapore 529889, Singapore","institution_ids":["https://openalex.org/I157582758","https://openalex.org/I2802225915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5052217593"],"corresponding_institution_ids":["https://openalex.org/I157582758","https://openalex.org/I2802225915"],"apc_list":null,"apc_paid":null,"fwci":1.2787,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.78291834,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"18","issue":"2","first_page":"143","last_page":"148"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9315999746322632,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9315999746322632,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.024399999529123306,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.022700000554323196,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatitis-c","display_name":"hepatitis C","score":0.9139999747276306},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.8450000286102295},{"id":"https://openalex.org/keywords/non-invasive-fibrosis-scores","display_name":"non-invasive fibrosis scores","score":0.7099999785423279},{"id":"https://openalex.org/keywords/apri","display_name":"APRI","score":0.8119999766349792},{"id":"https://openalex.org/keywords/fib-4-index","display_name":"FIB-4","score":0.9850000143051147},{"id":"https://openalex.org/keywords/transient-elastography","display_name":"transient elastography","score":0.8090000152587891},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.8870000243186951},{"id":"https://openalex.org/keywords/substance-use","display_name":"substance use","score":0.6690000295639038},{"id":"https://openalex.org/keywords/linkage-to-care","display_name":"linkage to care","score":0.8149999976158142},{"id":"https://openalex.org/keywords/hepatitis-c-elimination","display_name":"HCV elimination","score":0.6890000104904175},{"id":"https://openalex.org/keywords/aspartate-aminotransferase","display_name":"aspartate aminotransferase","score":0.7760000228881836},{"id":"https://openalex.org/keywords/platelet-count","display_name":"platelet count","score":0.984000027179718},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.5}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9386405348777771},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.7993173599243164},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7705214023590088},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.6445395946502686},{"id":"https://openalex.org/C2780826214","wikidata":"https://www.wikidata.org/wiki/Q1324974","display_name":"Transient elastography","level":4,"score":0.5955350399017334},{"id":"https://openalex.org/C2776455275","wikidata":"https://www.wikidata.org/wiki/Q154869","display_name":"Hepatitis C","level":2,"score":0.5467095375061035},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.47459930181503296},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.44854703545570374},{"id":"https://openalex.org/C2777766500","wikidata":"https://www.wikidata.org/wiki/Q360841","display_name":"Liver biopsy","level":3,"score":0.44084230065345764},{"id":"https://openalex.org/C2777382497","wikidata":"https://www.wikidata.org/wiki/Q6853","display_name":"Hepatitis B","level":2,"score":0.42852693796157837},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.4153003692626953},{"id":"https://openalex.org/C2994217296","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Liver fibrosis","level":3,"score":0.2795228064060211},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.16733863949775696},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D008111","descriptor_name":"Liver Function Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012846","descriptor_name":"Singapore","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019698","descriptor_name":"Hepatitis C, Chronic","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D019698","descriptor_name":"Hepatitis C, Chronic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D019698","descriptor_name":"Hepatitis C, Chronic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D019966","descriptor_name":"Substance-Related Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D054459","descriptor_name":"Elasticity Imaging Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.hbpd.2018.12.002","doi":"https://doi.org/10.1016/j.hbpd.2018.12.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.hbpd.2018.12.002","pdf_url":null,"source":{"id":"https://openalex.org/S2483261043","display_name":"Hepatobiliary & pancreatic diseases international","issn_l":"2352-9377","issn":["2352-9377","1499-3872"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatobiliary & Pancreatic Diseases International","raw_type":"journal-article"},{"id":"pmid:30558838","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30558838","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatobiliary & pancreatic diseases international : HBPD INT","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W216121951","https://openalex.org/W267117650","https://openalex.org/W560362739","https://openalex.org/W1895311754","https://openalex.org/W1970160203","https://openalex.org/W1985442918","https://openalex.org/W1997865776","https://openalex.org/W2017018616","https://openalex.org/W2025030892","https://openalex.org/W2027498662","https://openalex.org/W2063027176","https://openalex.org/W2088337379","https://openalex.org/W2104563699","https://openalex.org/W2115516378","https://openalex.org/W2117027295","https://openalex.org/W2126552035","https://openalex.org/W2128366104","https://openalex.org/W2134387088","https://openalex.org/W2143991614","https://openalex.org/W2150604286","https://openalex.org/W2154739921","https://openalex.org/W2170706646","https://openalex.org/W2192797316","https://openalex.org/W2280719849","https://openalex.org/W2382558799","https://openalex.org/W2462340700","https://openalex.org/W2578013986","https://openalex.org/W2591629519","https://openalex.org/W2607108876","https://openalex.org/W2620924543","https://openalex.org/W2623266106","https://openalex.org/W2743338523","https://openalex.org/W2790938901"],"related_works":["https://openalex.org/W7096803305","https://openalex.org/W4234695295","https://openalex.org/W1530532795","https://openalex.org/W3004154039","https://openalex.org/W7043969337","https://openalex.org/W6889751163","https://openalex.org/W4400146591","https://openalex.org/W2029826110","https://openalex.org/W3008256417","https://openalex.org/W3086532193"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-12-22T00:00:00"}