{"id":"https://openalex.org/W2904083402","doi":"https://doi.org/10.1111/mpp.12775","title":"Pseudozyma aphidis activates reactive oxygen species production, programmed cell death and morphological alterations in the necrotrophic fungus Botrytis cinerea","display_name":"Pseudozyma aphidis activates reactive oxygen species production, programmed cell death and morphological alterations in the necrotrophic fungus Botrytis cinerea","publication_year":2018,"publication_date":"2018-12-10","ids":{"openalex":"https://openalex.org/W2904083402","doi":"https://doi.org/10.1111/mpp.12775","mag":"2904083402","pmid":"https://pubmed.ncbi.nlm.nih.gov/30537338","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6637909"},"language":"en","primary_location":{"id":"doi:10.1111/mpp.12775","doi":"https://doi.org/10.1111/mpp.12775","is_oa":true,"landing_page_url":"https://doi.org/10.1111/mpp.12775","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/mpp.12775","source":{"id":"https://openalex.org/S207933444","display_name":"Molecular Plant Pathology","issn_l":"1364-3703","issn":["1364-3703","1464-6722"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Plant Pathology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/mpp.12775","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004760085","display_name":"Claudia E. Calder\u00f3n","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Claudia E. Calder\u00f3n","raw_affiliation_strings":["Department of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 76100 Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 76100 Israel","institution_ids":["https://openalex.org/I197251160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065810298","display_name":"Neta Rotem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Neta Rotem","raw_affiliation_strings":["Department of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 76100 Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 76100 Israel","institution_ids":["https://openalex.org/I197251160"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Raviv Harris","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Raviv Harris","raw_affiliation_strings":["Department of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 76100 Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 76100 Israel","institution_ids":["https://openalex.org/I197251160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046188822","display_name":"David Vela\u2010Corc\u00eda","orcid":"https://orcid.org/0000-0002-8641-9288","observed_orcids":["https://orcid.org/0000-0002-8641-9288"]},"institutions":[{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"David Vela\u2010Corc\u00eda","raw_affiliation_strings":["Department of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 76100 Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 76100 Israel","institution_ids":["https://openalex.org/I197251160"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016773252","display_name":"Maggie Levy","orcid":"https://orcid.org/0000-0003-4107-9387","observed_orcids":["https://orcid.org/0000-0003-4107-9387"]},"institutions":[{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Maggie Levy","raw_affiliation_strings":["Department of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 76100 Israel"],"raw_orcid":"https://orcid.org/0000-0003-4107-9387","affiliations":[{"raw_affiliation_string":"Department of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 76100 Israel","institution_ids":["https://openalex.org/I197251160"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5016773252"],"corresponding_institution_ids":["https://openalex.org/I197251160"],"apc_list":{"value":3330,"currency":"USD","value_usd":3330},"apc_paid":{"value":3330,"currency":"USD","value_usd":3330},"fwci":1.5069,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.83058453,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"20","issue":"4","first_page":"562","last_page":"574"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10076","display_name":"Plant-Microbe Interactions and Immunity","score":0.6187000274658203,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10076","display_name":"Plant-Microbe Interactions and Immunity","score":0.6187000274658203,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11900","display_name":"Fungal Plant Pathogen Control","score":0.28859999775886536,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10825","display_name":"Plant Pathogens and Fungal Diseases","score":0.025499999523162842,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pseudozyma-aphidis","display_name":"Pseudozyma aphidis","score":1.0},{"id":"https://openalex.org/keywords/botrytis-cinerea","display_name":"Botrytis cinerea","score":0.9990000128746033},{"id":"https://openalex.org/keywords/epiphytic-yeasts","display_name":"epiphytic yeasts","score":0.734000027179718},{"id":"https://openalex.org/keywords/biological-control-agents","display_name":"biological control agents","score":0.703000009059906},{"id":"https://openalex.org/keywords/antifungal-agents","display_name":"antifungal agents","score":0.8059999942779541},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9549999833106995},{"id":"https://openalex.org/keywords/programmed-cell-death","display_name":"programmed cell death","score":0.9980000257492065},{"id":"https://openalex.org/keywords/nutrient-competition","display_name":"nutrient competition","score":0.6890000104904175},{"id":"https://openalex.org/keywords/mycoparasitism","display_name":"mycoparasitism","score":0.7630000114440918},{"id":"https://openalex.org/keywords/induced-resistance","display_name":"induced resistance","score":0.6639999747276306},{"id":"https://openalex.org/keywords/antibiosis","display_name":"antibiosis","score":0.8140000104904175},{"id":"https://openalex.org/keywords/plant-pathogenic-fungi","display_name":"plant pathogenic fungi","score":0.6299999952316284}],"concepts":[{"id":"https://openalex.org/C2775867217","wikidata":"https://www.wikidata.org/wiki/Q1135851","display_name":"Botrytis cinerea","level":2,"score":0.9652127027511597},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8306930065155029},{"id":"https://openalex.org/C14225744","wikidata":"https://www.wikidata.org/wiki/Q770530","display_name":"Antibiosis","level":3,"score":0.7764573097229004},{"id":"https://openalex.org/C90080823","wikidata":"https://www.wikidata.org/wiki/Q193129","display_name":"Hypha","level":2,"score":0.7635658979415894},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6460058689117432},{"id":"https://openalex.org/C2779678110","wikidata":"https://www.wikidata.org/wiki/Q764","display_name":"Fungus","level":2,"score":0.4840259253978729},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.4766417443752289},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.4589579701423645},{"id":"https://openalex.org/C133479454","wikidata":"https://www.wikidata.org/wiki/Q326228","display_name":"Mycelium","level":2,"score":0.44124269485473633},{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.4235530197620392},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.4064045250415802},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.17773711681365967},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15965908765792847},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D014587","descriptor_name":"Ustilaginales","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020171","descriptor_name":"Botrytis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D025282","descriptor_name":"Mycelium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/mpp.12775","doi":"https://doi.org/10.1111/mpp.12775","is_oa":true,"landing_page_url":"https://doi.org/10.1111/mpp.12775","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/mpp.12775","source":{"id":"https://openalex.org/S207933444","display_name":"Molecular Plant Pathology","issn_l":"1364-3703","issn":["1364-3703","1464-6722"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Plant Pathology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6637909","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6637909","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Plant Pathol","raw_type":"Text"},{"id":"pmid:30537338","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30537338","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular plant pathology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/mpp.12775","doi":"https://doi.org/10.1111/mpp.12775","is_oa":true,"landing_page_url":"https://doi.org/10.1111/mpp.12775","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/mpp.12775","source":{"id":"https://openalex.org/S207933444","display_name":"Molecular Plant Pathology","issn_l":"1364-3703","issn":["1364-3703","1464-6722"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Plant Pathology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6875,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1279836646","display_name":null,"funder_award_id":"256-0484-99","funder_id":"https://openalex.org/F4320322739","funder_display_name":"Ministry of Agriculture and Rural Development"},{"id":"https://openalex.org/G5113725600","display_name":null,"funder_award_id":"1375/14","funder_id":"https://openalex.org/F4320322252","funder_display_name":"Israel Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320322252","display_name":"Israel Science Foundation","ror":"https://ror.org/04sazxf24"},{"id":"https://openalex.org/F4320322739","display_name":"Ministry of Agriculture and Rural Development","ror":"https://ror.org/05e6hcm17"},{"id":"https://openalex.org/F4320333299","display_name":"Biomedical Advanced Research and Development Authority","ror":"https://ror.org/029y69023"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2904083402.pdf","grobid_xml":"https://content.openalex.org/works/W2904083402.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W15885085","https://openalex.org/W104671088","https://openalex.org/W654089686","https://openalex.org/W1605678365","https://openalex.org/W1951740155","https://openalex.org/W1969369722","https://openalex.org/W1985049276","https://openalex.org/W1988780738","https://openalex.org/W1991659089","https://openalex.org/W2003003290","https://openalex.org/W2010262570","https://openalex.org/W2011440791","https://openalex.org/W2018008972","https://openalex.org/W2022159464","https://openalex.org/W2028654690","https://openalex.org/W2036433035","https://openalex.org/W2037690018","https://openalex.org/W2041038630","https://openalex.org/W2041907563","https://openalex.org/W2045785873","https://openalex.org/W2046463657","https://openalex.org/W2047469625","https://openalex.org/W2048542398","https://openalex.org/W2054075526","https://openalex.org/W2054901867","https://openalex.org/W2055106953","https://openalex.org/W2077137058","https://openalex.org/W2080857572","https://openalex.org/W2087265897","https://openalex.org/W2087765586","https://openalex.org/W2095402615","https://openalex.org/W2098785950","https://openalex.org/W2106759368","https://openalex.org/W2114231629","https://openalex.org/W2115759619","https://openalex.org/W2119346973","https://openalex.org/W2128646224","https://openalex.org/W2138231948","https://openalex.org/W2139456772","https://openalex.org/W2150316927","https://openalex.org/W2151926019","https://openalex.org/W2152733321","https://openalex.org/W2168624838","https://openalex.org/W2176826144","https://openalex.org/W2182045502","https://openalex.org/W2314780642","https://openalex.org/W2331481621","https://openalex.org/W2342271828","https://openalex.org/W2346643113","https://openalex.org/W2418193167","https://openalex.org/W2434846167","https://openalex.org/W2561444988","https://openalex.org/W2606885557","https://openalex.org/W2611449433","https://openalex.org/W2621454200","https://openalex.org/W2765769847"],"related_works":["https://openalex.org/W2047469625","https://openalex.org/W2041038630","https://openalex.org/W3122330848","https://openalex.org/W2088189594","https://openalex.org/W4410898130","https://openalex.org/W7096446396","https://openalex.org/W2054075526","https://openalex.org/W4406807133","https://openalex.org/W1985049276","https://openalex.org/W4406187196"],"abstract_inverted_index":{"Many":[0],"types":[1],"of":[2,31,42,102,144,152],"yeast":[3,63],"have":[4,49,58],"been":[5,50],"studied":[6],"in":[7,45,110],"the":[8,51,61,95,100,139,162],"last":[9],"few":[10],"years":[11],"as":[12],"potential":[13],"biocontrol":[14],"agents":[15],"against":[16,161],"different":[17],"phytopathogenic":[18],"fungi.":[19],"Their":[20],"ability":[21,141],"to":[22,81,127],"control":[23],"plant":[24,163],"diseases":[25],"is":[26],"mainly":[27],"through":[28,69],"combined":[29],"modes":[30,151],"action.":[32],"Among":[33],"them,":[34],"antibiosis,":[35],"competition":[36],"for":[37,89,154],"nutrients":[38],"and":[39,47,72,85,106,117,134,142,157],"niches,":[40],"induction":[41],"systemic":[43],"resistance":[44,71],"plants":[46],"mycoparasitism":[48],"most":[52],"studied.":[53],"In":[54],"previous":[55],"work,":[56],"we":[57,75],"established":[59],"that":[60,77,94],"epiphytic":[62],"Pseudozyma":[64],"aphidis":[65,79,116,156],"inhibits":[66],"Botrytis":[67],"cinerea":[68,83,112,124],"induced":[70],"antibiosis.":[73],"Here,":[74],"demonstrate":[76],"P.":[78,115,155],"adheres":[80],"B.":[82,111,123,145,165],"hyphae":[84],"competes":[86],"with":[87],"them":[88],"nutrients.":[90],"We":[91],"further":[92],"show":[93],"secreted":[96,119],"antifungal":[97,159],"compounds":[98,120,160],"activate":[99],"production":[101],"reactive":[103],"oxygen":[104],"species":[105],"programmed":[107],"cell":[108],"death":[109],"mycelium.":[113],"Finally,":[114],"its":[118,158],"negatively":[121],"affect":[122],"hyphae,":[125],"leading":[126],"morphological":[128],"alterations,":[129],"including":[130],"hyphal":[131],"curliness,":[132],"vacuolization":[133],"branching,":[135],"which":[136],"presumably":[137],"affects":[138],"colonization":[140],"infectivity":[143],"cinerea.":[146,166],"This":[147],"study":[148],"demonstrates":[149],"additional":[150],"action":[153],"pathogen":[164]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-12-22T00:00:00"}