{"id":"https://openalex.org/W2903564584","doi":"https://doi.org/10.1007/s12192-018-0950-x","title":"The Hsp70/J-protein machinery of the African trypanosome, Trypanosoma brucei","display_name":"The Hsp70/J-protein machinery of the African trypanosome, Trypanosoma brucei","publication_year":2018,"publication_date":"2018-12-01","ids":{"openalex":"https://openalex.org/W2903564584","doi":"https://doi.org/10.1007/s12192-018-0950-x","mag":"2903564584","pmid":"https://pubmed.ncbi.nlm.nih.gov/30506377","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6363631"},"language":"en","primary_location":{"id":"doi:10.1007/s12192-018-0950-x","doi":"https://doi.org/10.1007/s12192-018-0950-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12192-018-0950-x","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12192-018-0950-x.pdf","source":{"id":"https://openalex.org/S5415759","display_name":"Cell Stress and Chaperones","issn_l":"1355-8145","issn":["1355-8145","1466-1268"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","norway-1","oarl","poland-70"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Stress and Chaperones","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s12192-018-0950-x.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088504174","display_name":"Stephen John Bentley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I203238179","display_name":"Rhodes University","ror":"https://ror.org/016sewp10","country_code":"ZA","type":"education","lineage":["https://openalex.org/I203238179"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Stephen John Bentley","raw_affiliation_strings":["Biotechnology Innovation Centre, Rhodes University, Grahamstown, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biotechnology Innovation Centre, Rhodes University, Grahamstown, South Africa","institution_ids":["https://openalex.org/I203238179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056297293","display_name":"Miebaka Jamabo","orcid":"https://orcid.org/0000-0001-6386-1914","observed_orcids":["https://orcid.org/0000-0001-6386-1914"]},"institutions":[{"id":"https://openalex.org/I203238179","display_name":"Rhodes University","ror":"https://ror.org/016sewp10","country_code":"ZA","type":"education","lineage":["https://openalex.org/I203238179"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Miebaka Jamabo","raw_affiliation_strings":["Biotechnology Innovation Centre, Rhodes University, Grahamstown, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biotechnology Innovation Centre, Rhodes University, Grahamstown, South Africa","institution_ids":["https://openalex.org/I203238179"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018667566","display_name":"Aileen Boshoff","orcid":"https://orcid.org/0000-0001-6551-8941","observed_orcids":["https://orcid.org/0000-0001-6551-8941"]},"institutions":[{"id":"https://openalex.org/I203238179","display_name":"Rhodes University","ror":"https://ror.org/016sewp10","country_code":"ZA","type":"education","lineage":["https://openalex.org/I203238179"]}],"countries":["ZA"],"is_corresponding":true,"raw_author_name":"Aileen Boshoff","raw_affiliation_strings":["Biotechnology Innovation Centre, Rhodes University, Grahamstown, South Africa. a.boshoff@ru.ac.za","Biotechnology Innovation Centre, Rhodes University, Grahamstown, South Africa"],"raw_orcid":"https://orcid.org/0000-0001-6551-8941","affiliations":[{"raw_affiliation_string":"Biotechnology Innovation Centre, Rhodes University, Grahamstown, South Africa. a.boshoff@ru.ac.za","institution_ids":["https://openalex.org/I203238179"]},{"raw_affiliation_string":"Biotechnology Innovation Centre, Rhodes University, Grahamstown, South Africa","institution_ids":["https://openalex.org/I203238179"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5018667566"],"corresponding_institution_ids":["https://openalex.org/I203238179"],"apc_list":{"value":2850,"currency":"USD","value_usd":2850},"apc_paid":{"value":2850,"currency":"USD","value_usd":2850},"fwci":0.4683,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.58281974,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"24","issue":"1","first_page":"125","last_page":"148"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.6269999742507935,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.6269999742507935,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":0.37209999561309814,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10296","display_name":"Vector-borne infectious diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hsp70","display_name":"HSP70","score":0.8759999871253967},{"id":"https://openalex.org/keywords/j-proteins","display_name":"J-proteins","score":0.9860000014305115},{"id":"https://openalex.org/keywords/trypanosoma-brucei","display_name":"Trypanosoma brucei","score":0.9829999804496765},{"id":"https://openalex.org/keywords/human-african-trypanosomiasis","display_name":"sleeping sickness","score":0.9819999933242798},{"id":"https://openalex.org/keywords/heat-shock-proteins","display_name":"heat shock proteins","score":0.8410000205039978},{"id":"https://openalex.org/keywords/molecular-chaperones","display_name":"molecular chaperones","score":0.671999990940094},{"id":"https://openalex.org/keywords/proteostasis","display_name":"proteostasis","score":0.8169999718666077},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.675000011920929},{"id":"https://openalex.org/keywords/kinetoplastid-parasites","display_name":"kinetoplastid parasites","score":0.7950000166893005},{"id":"https://openalex.org/keywords/genome-annotation","display_name":"genome annotation","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C2779502636","wikidata":"https://www.wikidata.org/wiki/Q33244","display_name":"Trypanosoma brucei","level":3,"score":0.9117946624755859},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8400307297706604},{"id":"https://openalex.org/C2781452922","wikidata":"https://www.wikidata.org/wiki/Q2892805","display_name":"Proteostasis","level":2,"score":0.6388148069381714},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.5380299687385559},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5345503687858582},{"id":"https://openalex.org/C2778792689","wikidata":"https://www.wikidata.org/wiki/Q203133","display_name":"African trypanosomiasis","level":3,"score":0.5327309370040894},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.5180766582489014},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5102818012237549},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5045284032821655},{"id":"https://openalex.org/C188018408","wikidata":"https://www.wikidata.org/wiki/Q24779822","display_name":"Tetratricopeptide","level":3,"score":0.48484790325164795},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4590545892715454},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.44580426812171936},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.23859110474586487},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19352799654006958},{"id":"https://openalex.org/C2778143080","wikidata":"https://www.wikidata.org/wiki/Q2443552","display_name":"Trypanosomiasis","level":2,"score":0.14452692866325378},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014346","descriptor_name":"Trypanosoma brucei brucei","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018840","descriptor_name":"HSP70 Heat-Shock Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/s12192-018-0950-x","doi":"https://doi.org/10.1007/s12192-018-0950-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12192-018-0950-x","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12192-018-0950-x.pdf","source":{"id":"https://openalex.org/S5415759","display_name":"Cell Stress and Chaperones","issn_l":"1355-8145","issn":["1355-8145","1466-1268"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","norway-1","oarl","poland-70"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Stress and Chaperones","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5569838","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6363631","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6363631","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6363631","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Stress Chaperones","raw_type":"Text"},{"id":"pmid:30506377","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30506377","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell stress & chaperones","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1007/s12192-018-0950-x","doi":"https://doi.org/10.1007/s12192-018-0950-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12192-018-0950-x","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12192-018-0950-x.pdf","source":{"id":"https://openalex.org/S5415759","display_name":"Cell Stress and Chaperones","issn_l":"1355-8145","issn":["1355-8145","1466-1268"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","medline","norway-1","oarl","poland-70"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Stress and Chaperones","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2903564584.pdf","grobid_xml":"https://content.openalex.org/works/W2903564584.grobid-xml"},"referenced_works_count":151,"referenced_works":["https://openalex.org/W55883085","https://openalex.org/W1536886974","https://openalex.org/W1558232630","https://openalex.org/W1569413678","https://openalex.org/W1706238475","https://openalex.org/W1794209129","https://openalex.org/W1879327185","https://openalex.org/W1918276289","https://openalex.org/W1939117002","https://openalex.org/W1944012495","https://openalex.org/W1958773130","https://openalex.org/W1963770237","https://openalex.org/W1970341475","https://openalex.org/W1971580290","https://openalex.org/W1972110853","https://openalex.org/W1972121275","https://openalex.org/W1975834426","https://openalex.org/W1976186717","https://openalex.org/W1976633708","https://openalex.org/W1977979139","https://openalex.org/W1979275004","https://openalex.org/W1980410619","https://openalex.org/W1980772064","https://openalex.org/W1983082920","https://openalex.org/W1984246637","https://openalex.org/W1984448408","https://openalex.org/W1985778015","https://openalex.org/W1985901907","https://openalex.org/W1986087947","https://openalex.org/W1987202538","https://openalex.org/W1988477462","https://openalex.org/W1988671518","https://openalex.org/W1990972186","https://openalex.org/W1991076291","https://openalex.org/W1995112257","https://openalex.org/W2000667938","https://openalex.org/W2001353593","https://openalex.org/W2002840394","https://openalex.org/W2002904173","https://openalex.org/W2004538040","https://openalex.org/W2005070472","https://openalex.org/W2006627086","https://openalex.org/W2008165309","https://openalex.org/W2011414653","https://openalex.org/W2013204504","https://openalex.org/W2017519756","https://openalex.org/W2018983668","https://openalex.org/W2019561141","https://openalex.org/W2028704597","https://openalex.org/W2028705478","https://openalex.org/W2032035843","https://openalex.org/W2035989713","https://openalex.org/W2037306892","https://openalex.org/W2038186997","https://openalex.org/W2038481055","https://openalex.org/W2039855583","https://openalex.org/W2042350133","https://openalex.org/W2043433277","https://openalex.org/W2047477750","https://openalex.org/W2048525855","https://openalex.org/W2049631853","https://openalex.org/W2052002049","https://openalex.org/W2061246349","https://openalex.org/W2063717615","https://openalex.org/W2065362324","https://openalex.org/W2066437545","https://openalex.org/W2066557222","https://openalex.org/W2067381848","https://openalex.org/W2069289881","https://openalex.org/W2072356380","https://openalex.org/W2073862341","https://openalex.org/W2073920150","https://openalex.org/W2078174957","https://openalex.org/W2078458710","https://openalex.org/W2079737911","https://openalex.org/W2081155723","https://openalex.org/W2085498335","https://openalex.org/W2089400513","https://openalex.org/W2092947800","https://openalex.org/W2094201044","https://openalex.org/W2100291894","https://openalex.org/W2101553897","https://openalex.org/W2102904980","https://openalex.org/W2103017472","https://openalex.org/W2106053335","https://openalex.org/W2109936231","https://openalex.org/W2110238152","https://openalex.org/W2111141244","https://openalex.org/W2112330287","https://openalex.org/W2117692658","https://openalex.org/W2118153758","https://openalex.org/W2119029533","https://openalex.org/W2119999468","https://openalex.org/W2121991815","https://openalex.org/W2122547807","https://openalex.org/W2123139638","https://openalex.org/W2126913120","https://openalex.org/W2127435093","https://openalex.org/W2129843453","https://openalex.org/W2133641675","https://openalex.org/W2135318540","https://openalex.org/W2137015675","https://openalex.org/W2137265564","https://openalex.org/W2137360605","https://openalex.org/W2137424160","https://openalex.org/W2138395558","https://openalex.org/W2143087925","https://openalex.org/W2143677078","https://openalex.org/W2144936254","https://openalex.org/W2145694104","https://openalex.org/W2146620899","https://openalex.org/W2146683088","https://openalex.org/W2148299087","https://openalex.org/W2148396143","https://openalex.org/W2150046668","https://openalex.org/W2151877638","https://openalex.org/W2154290102","https://openalex.org/W2154927069","https://openalex.org/W2155744824","https://openalex.org/W2157106689","https://openalex.org/W2158173168","https://openalex.org/W2158427156","https://openalex.org/W2160070766","https://openalex.org/W2161257332","https://openalex.org/W2161670666","https://openalex.org/W2163627198","https://openalex.org/W2166859880","https://openalex.org/W2180488799","https://openalex.org/W2180711417","https://openalex.org/W2216844357","https://openalex.org/W2281879936","https://openalex.org/W2292165437","https://openalex.org/W2311203695","https://openalex.org/W2344575936","https://openalex.org/W2345866656","https://openalex.org/W2382474752","https://openalex.org/W2412940349","https://openalex.org/W2465752335","https://openalex.org/W2466100475","https://openalex.org/W2585667824","https://openalex.org/W2613197902","https://openalex.org/W2736984476","https://openalex.org/W2779358207","https://openalex.org/W4244736178","https://openalex.org/W6646199352","https://openalex.org/W6679992645","https://openalex.org/W6684550386","https://openalex.org/W6688667111","https://openalex.org/W6704775162","https://openalex.org/W6817776979","https://openalex.org/W6838157350"],"related_works":["https://openalex.org/W2989652435","https://openalex.org/W2005070472","https://openalex.org/W3136959959","https://openalex.org/W4399086348","https://openalex.org/W4297009367","https://openalex.org/W2756100407","https://openalex.org/W7096733153","https://openalex.org/W2008165309","https://openalex.org/W4394010165","https://openalex.org/W3173721382"],"abstract_inverted_index":{"The":[0,116,145],"etiological":[1],"agent":[2],"of":[3,18,35,47,64,70,74,86,106,141,183,208,220],"the":[4,36,68,71,75,87,107,139,181,206,218,221],"neglected":[5],"tropical":[6],"disease":[7],"African":[8,222],"trypanosomiasis,":[9],"Trypanosoma":[10],"brucei,":[11,135],"possesses":[12],"an":[13,79],"expanded":[14],"and":[15,33,45,67,81,95,103,111,118,122,147,161,171,224,227],"diverse":[16],"repertoire":[17],"heat":[19],"shock":[20],"proteins,":[21],"which":[22,156],"have":[23],"been":[24],"implicated":[25],"in":[26,43,83,90,130],"cytoprotection,":[27],"differentiation,":[28],"as":[29,31,54,136,138,230],"well":[30,137],"progression":[32],"transmission":[34],"disease.":[37],"Hsp70":[38,110,117,146,169,226],"plays":[39],"a":[40,55,213],"crucial":[41],"role":[42],"proteostasis,":[44],"inhibition":[46],"its":[48],"interactions":[49,229],"with":[50],"co-chaperones":[51],"is":[52,203],"emerging":[53],"potential":[56,142,231],"therapeutic":[57],"target":[58],"for":[59,216],"numerous":[60,152],"diseases.":[61],"In":[62,164],"light":[63],"genome":[65,72],"annotations":[66],"release":[69],"sequence":[73],"human":[76],"infective":[77],"subspecies,":[78],"updated":[80],"current":[82],"silico":[84],"overview":[85],"Hsp70/J-protein":[88],"machinery":[89],"both":[91,184],"T.":[92,96,108,134,185],"brucei":[93,94,97,109,186],"gambiense":[98],"was":[99],"conducted.":[100],"Functional,":[101],"structural,":[102],"evolutionary":[104],"analyses":[105],"J-protein":[112,228],"families":[113],"were":[114,126,149,175],"performed.":[115],"J-proteins":[119,148,174,194],"from":[120,133,151],"humans":[121],"selected":[123],"kinetoplastid":[124],"parasites":[125],"used":[127],"to":[128,177],"assist":[129],"identifying":[131],"proteins":[132,170],"prediction":[140],"Hsp70-J-protein":[143],"partnerships.":[144],"mined":[150],"genome-wide":[153],"proteomics":[154],"studies,":[155],"included":[157],"different":[158],"lifecycle":[159],"stages":[160],"subcellular":[162],"localisations.":[163],"this":[165,209],"study,":[166],"12":[167],"putative":[168,173],"67":[172],"identified":[176],"be":[178],"encoded":[179],"on":[180],"genomes":[182],"subspecies.":[187],"Interestingly":[188],"there":[189],"are":[190],"6":[191],"type":[192],"III":[193],"that":[195,205],"possess":[196],"tetratricopeptide":[197],"repeat-containing":[198],"(TPR)":[199],"motifs.":[200],"Overall,":[201],"it":[202],"envisioned":[204],"results":[207],"study":[210],"will":[211],"provide":[212],"future":[214],"context":[215],"studying":[217],"biology":[219],"trypanosome":[223],"evaluating":[225],"drug":[232],"targets.":[233]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-12-11T00:00:00"}
