{"id":"https://openalex.org/W2902814587","doi":"https://doi.org/10.1002/bdr2.1417","title":"Submarine exposure guideline recommendations for carbon dioxide based on the prenatal developmental effects of exposure in rats","display_name":"Submarine exposure guideline recommendations for carbon dioxide based on the prenatal developmental effects of exposure in rats","publication_year":2018,"publication_date":"2018-12-03","ids":{"openalex":"https://openalex.org/W2902814587","doi":"https://doi.org/10.1002/bdr2.1417","mag":"2902814587","pmid":"https://pubmed.ncbi.nlm.nih.gov/30511437"},"language":"en","primary_location":{"id":"doi:10.1002/bdr2.1417","doi":"https://doi.org/10.1002/bdr2.1417","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bdr2.1417","pdf_url":null,"source":{"id":"https://openalex.org/S23975315","display_name":"Birth Defects Research","issn_l":"2472-1727","issn":["2472-1727"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Birth Defects Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"William R. Howard","orcid":"https://orcid.org/0000-0002-9688-1214","observed_orcids":["https://orcid.org/0000-0002-9688-1214"]},"institutions":[{"id":"https://openalex.org/I2799950915","display_name":"Wright-Patterson Air Force Base","ror":"https://ror.org/0097e1k27","country_code":"US","type":"other","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2799950915","https://openalex.org/I4210089612","https://openalex.org/I4210102105"]},{"id":"https://openalex.org/I4405257593","display_name":"Naval Medical Research Unit DAYTON","ror":"https://ror.org/05egqah77","country_code":"US","type":"government","lineage":["https://openalex.org/I1312537475","https://openalex.org/I1330347796","https://openalex.org/I3130687028","https://openalex.org/I4391768141","https://openalex.org/I4405257593"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"William R. Howard","raw_affiliation_strings":["Naval Medical Research Unit Dayton, Wright Patterson AFB, Dayton, Ohio"],"raw_orcid":"https://orcid.org/0000-0002-9688-1214","affiliations":[{"raw_affiliation_string":"Naval Medical Research Unit Dayton, Wright Patterson AFB, Dayton, Ohio","institution_ids":["https://openalex.org/I2799950915","https://openalex.org/I4405257593"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Brian Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1280259254","display_name":"Henry M. Jackson Foundation","ror":"https://ror.org/04q9tew83","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1280259254"]},{"id":"https://openalex.org/I2799950915","display_name":"Wright-Patterson Air Force Base","ror":"https://ror.org/0097e1k27","country_code":"US","type":"other","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2799950915","https://openalex.org/I4210089612","https://openalex.org/I4210102105"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian Wong","raw_affiliation_strings":["Henry M. Jackson Foundation for the Advancement of Military Medicine, Wright Patterson AFB, Dayton, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Henry M. Jackson Foundation for the Advancement of Military Medicine, Wright Patterson AFB, Dayton, Ohio","institution_ids":["https://openalex.org/I1280259254","https://openalex.org/I2799950915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061249677","display_name":"Kimberly S. B. Yeager","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4389425366","display_name":"Oak Ridge Institute for Science and Education","ror":"https://ror.org/040vxhp34","country_code":"US","type":"education","lineage":["https://openalex.org/I1281378812","https://openalex.org/I1330989302","https://openalex.org/I4389425366"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly S. B. Yeager","raw_affiliation_strings":["Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee","institution_ids":["https://openalex.org/I4389425366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062442137","display_name":"Donald G. Stump","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126295","display_name":"Charles River Laboratories (United States)","ror":"https://ror.org/03ndmsg87","country_code":"US","type":"company","lineage":["https://openalex.org/I4210126295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald G. Stump","raw_affiliation_strings":["Charles River Laboratories, Ashland, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charles River Laboratories, Ashland, Ohio","institution_ids":["https://openalex.org/I4210126295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091333129","display_name":"Tammye L. Edwards","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126295","display_name":"Charles River Laboratories (United States)","ror":"https://ror.org/03ndmsg87","country_code":"US","type":"company","lineage":["https://openalex.org/I4210126295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tammye Edwards","raw_affiliation_strings":["Charles River Laboratories, Ashland, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charles River Laboratories, Ashland, Ohio","institution_ids":["https://openalex.org/I4210126295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112401126","display_name":"R. Arden James","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1280259254","display_name":"Henry M. Jackson Foundation","ror":"https://ror.org/04q9tew83","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1280259254"]},{"id":"https://openalex.org/I2799950915","display_name":"Wright-Patterson Air Force Base","ror":"https://ror.org/0097e1k27","country_code":"US","type":"other","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2799950915","https://openalex.org/I4210089612","https://openalex.org/I4210102105"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Arden James","raw_affiliation_strings":["Henry M. Jackson Foundation for the Advancement of Military Medicine, Wright Patterson AFB, Dayton, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Henry M. Jackson Foundation for the Advancement of Military Medicine, Wright Patterson AFB, Dayton, Ohio","institution_ids":["https://openalex.org/I1280259254","https://openalex.org/I2799950915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041566020","display_name":"Michelle R. Goodwin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1280259254","display_name":"Henry M. Jackson Foundation","ror":"https://ror.org/04q9tew83","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1280259254"]},{"id":"https://openalex.org/I2799950915","display_name":"Wright-Patterson Air Force Base","ror":"https://ror.org/0097e1k27","country_code":"US","type":"other","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2799950915","https://openalex.org/I4210089612","https://openalex.org/I4210102105"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michelle R. Goodwin","raw_affiliation_strings":["Henry M. Jackson Foundation for the Advancement of Military Medicine, Wright Patterson AFB, Dayton, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Henry M. Jackson Foundation for the Advancement of Military Medicine, Wright Patterson AFB, Dayton, Ohio","institution_ids":["https://openalex.org/I1280259254","https://openalex.org/I2799950915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038393989","display_name":"Michael L. Gargas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799950915","display_name":"Wright-Patterson Air Force Base","ror":"https://ror.org/0097e1k27","country_code":"US","type":"other","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2799950915","https://openalex.org/I4210089612","https://openalex.org/I4210102105"]},{"id":"https://openalex.org/I4405257593","display_name":"Naval Medical Research Unit DAYTON","ror":"https://ror.org/05egqah77","country_code":"US","type":"government","lineage":["https://openalex.org/I1312537475","https://openalex.org/I1330347796","https://openalex.org/I3130687028","https://openalex.org/I4391768141","https://openalex.org/I4405257593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael L. Gargas","raw_affiliation_strings":["Naval Medical Research Unit Dayton, Wright Patterson AFB, Dayton, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Naval Medical Research Unit Dayton, Wright Patterson AFB, Dayton, Ohio","institution_ids":["https://openalex.org/I2799950915","https://openalex.org/I4405257593"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2799950915","https://openalex.org/I4405257593"],"apc_list":{"value":3700,"currency":"USD","value_usd":3700},"apc_paid":null,"fwci":0.63,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.77071317,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"111","issue":"1","first_page":"26","last_page":"33"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13315","display_name":"Occupational Health and Safety in Workplaces","score":0.5321999788284302,"subfield":{"id":"https://openalex.org/subfields/3609","display_name":"Occupational Therapy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13315","display_name":"Occupational Health and Safety in Workplaces","score":0.5321999788284302,"subfield":{"id":"https://openalex.org/subfields/3609","display_name":"Occupational Therapy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11002","display_name":"Indoor Air Quality and Microbial Exposure","score":0.062199998646974564,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.05979999899864197,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbon-dioxide","display_name":"carbon dioxide","score":0.7879999876022339},{"id":"https://openalex.org/keywords/prenatal-exposure","display_name":"prenatal exposure","score":0.7039999961853027},{"id":"https://openalex.org/keywords/fetal-resorption","display_name":"fetal resorption","score":0.6710000038146973},{"id":"https://openalex.org/keywords/fetal-viability","display_name":"fetal viability","score":0.4790000021457672},{"id":"https://openalex.org/keywords/exposure-limits","display_name":"exposure limits","score":0.8240000009536743},{"id":"https://openalex.org/keywords/no-observed-adverse-effect-level","display_name":"no-observed-adverse-effect level","score":0.8100000023841858},{"id":"https://openalex.org/keywords/lowest-observed-adverse-effect-level","display_name":"lowest observed adverse effect level","score":0.9869999885559082},{"id":"https://openalex.org/keywords/point-of-departure","display_name":"point of departure","score":0.9139999747276306},{"id":"https://openalex.org/keywords/nuclear-submarines","display_name":"nuclear submarines","score":0.5759999752044678}],"concepts":[{"id":"https://openalex.org/C2780182762","wikidata":"https://www.wikidata.org/wiki/Q1630279","display_name":"Guideline","level":2,"score":0.6880174279212952},{"id":"https://openalex.org/C3018923374","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Prenatal exposure","level":4,"score":0.5637096166610718},{"id":"https://openalex.org/C121327165","wikidata":"https://www.wikidata.org/wiki/Q2811","display_name":"Submarine","level":2,"score":0.44220080971717834},{"id":"https://openalex.org/C530467964","wikidata":"https://www.wikidata.org/wiki/Q1997","display_name":"Carbon dioxide","level":2,"score":0.4414498507976532},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.3882290720939636},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.3591775596141815},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.333554744720459},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.32868683338165283},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19309255480766296},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.18953165411949158},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.07781049609184265},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.06618255376815796},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.06344375014305115},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.053571879863739014},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011297","descriptor_name":"Prenatal Exposure Delayed Effects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012098","descriptor_name":"Reproduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013366","descriptor_name":"Submarine Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D013366","descriptor_name":"Submarine Medicine","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017408","descriptor_name":"Guidelines as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019055","descriptor_name":"No-Observed-Adverse-Effect Level","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047109","descriptor_name":"Fetal Development","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/bdr2.1417","doi":"https://doi.org/10.1002/bdr2.1417","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bdr2.1417","pdf_url":null,"source":{"id":"https://openalex.org/S23975315","display_name":"Birth Defects Research","issn_l":"2472-1727","issn":["2472-1727"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Birth Defects Research","raw_type":"journal-article"},{"id":"pmid:30511437","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30511437","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Birth defects research","raw_type":"Journal Article"},{"id":"pmh:oai:osti.gov:1786134","doi":null,"is_oa":false,"landing_page_url":"https://www.osti.gov/biblio/1786134","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320337504","display_name":"Research and Development","ror":"https://ror.org/027s68j25"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1563585988","https://openalex.org/W1965313406","https://openalex.org/W1977226572","https://openalex.org/W1984969400","https://openalex.org/W1988729939","https://openalex.org/W1994913657","https://openalex.org/W2004021051","https://openalex.org/W2014509516","https://openalex.org/W2014538668","https://openalex.org/W2039675138","https://openalex.org/W2041282815","https://openalex.org/W2056807152","https://openalex.org/W2168605283","https://openalex.org/W2433485625","https://openalex.org/W2775086384","https://openalex.org/W3022997872","https://openalex.org/W4212783336","https://openalex.org/W4234508015"],"related_works":["https://openalex.org/W322987898","https://openalex.org/W215048067","https://openalex.org/W230197651","https://openalex.org/W302377334","https://openalex.org/W2169288219","https://openalex.org/W4236152180","https://openalex.org/W2003016704","https://openalex.org/W4386513352","https://openalex.org/W636291420","https://openalex.org/W290392770"],"abstract_inverted_index":{"Background":[0],"To":[1],"protect":[2,82],"crewmember":[3],"health,":[4],"the":[5,39,45,62,150,240],"U.S.":[6,76],"Navy":[7,65,77],"sets":[8],"exposure":[9,31,53,78,125,191,205,228,243],"limits":[10,79,126],"for":[11,35,50,124,127,188,210],"more":[12],"than":[13],"200":[14],"components":[15],"of":[16,21,29,41,101,137,146,165,175,183,185,208],"submarine":[17],"atmospheres.":[18],"The":[19,155,177],"addition":[20],"females":[22],"to":[23,81,97,111,199,223],"nuclear":[24],"submarines":[25],"required":[26],"a":[27,57,68,141,158,168,181,201,226,230],"reevaluation":[28],"these":[30],"limits,":[32],"originally":[33],"established":[34],"all\u2010male":[36],"crews.":[37],"In":[38],"case":[40],"carbon":[42],"dioxide":[43],"(CO2),":[44],"only":[46],"available":[47],"data":[48],"suitable":[49],"deriving":[51,189],"an":[52,132,190],"limit":[54,206,244],"were":[55,95,114,118,131],"from":[56,107,225],"2010":[58],"study":[59],"sponsored":[60],"by":[61],"British":[63],"Royal":[64],"that":[66,215,239],"reported":[67],"debatable":[69],"interpretation":[70],"casting":[71],"doubt":[72],"on":[73],"whether":[74],"current":[75],"served":[80],"fetal":[83],"developmental":[84,217],"health.":[85],"Methods":[86],"About":[87],"120":[88],"time\u2010mated":[89],"female":[90],"Sprague\u2013Dawley":[91],"rats":[92],"(Crl:":[93],"CD[SD])":[94],"exposed":[96],"CO2":[98,128,152,187],"at":[99,229],"levels":[100],"1.5%,":[102],"2.0%,":[103],"2.5%,":[104],"and":[105,116,140,167],"3.0%":[106,151],"gestation":[108],"days":[109],"6":[110],"20.":[112],"Dams":[113],"euthanized":[115],"fetuses":[117,148],"examined.":[119],"Results":[120],"Findings":[121],"with":[122],"implications":[123],"during":[129,233],"pregnancy":[130],"increased":[133],"mean":[134,143],"litter":[135,144],"proportion":[136,145],"early":[138],"resorptions":[139],"lower":[142],"viable":[147],"in":[149,218],"group.":[153],"Conclusion":[154],"results":[156,178],"yield":[157],"No":[159],"Observed":[160,170],"Adverse":[161,171],"Effect":[162,172],"Level":[163,173],"(NOAEL)":[164],"2.5%":[166,186],"Lowest":[169],"(LOAEL)":[174],"3.0%.":[176],"reasonably":[179],"allow":[180],"point":[182,232],"departure":[184],"recommendation.":[192],"An":[193],"interspecies":[194],"uncertainty":[195],"factor":[196],"was":[197],"applied":[198],"derive":[200],"recommended":[202,238],"90\u2010day":[203],"continuous":[204],"(CEL)":[207],"0.8%":[209],"CO2.":[211],"As":[212],"reproductive":[213],"endpoints":[214],"are":[216],"nature":[219],"must":[220],"be":[221,247],"assumed":[222],"result":[224],"single":[227],"critical":[231],"gestation,":[234],"it":[235],"is":[236],"further":[237],"24\u2010hr":[241],"emergency":[242],"(EEL)":[245],"also":[246],"0.8%.":[248]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-12-11T00:00:00"}