{"id":"https://openalex.org/W2902321726","doi":"https://doi.org/10.1016/j.bbadis.2018.11.007","title":"Functions and dysfunctions of nitric oxide in brain","display_name":"Functions and dysfunctions of nitric oxide in brain","publication_year":2018,"publication_date":"2018-11-27","ids":{"openalex":"https://openalex.org/W2902321726","doi":"https://doi.org/10.1016/j.bbadis.2018.11.007","mag":"2902321726","pmid":"https://pubmed.ncbi.nlm.nih.gov/30500433"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbadis.2018.11.007","doi":"https://doi.org/10.1016/j.bbadis.2018.11.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbadis.2018.11.007","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0925443918304526/pdf","source":{"id":"https://openalex.org/S4210173099","display_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","issn_l":"0925-4439","issn":["0925-4439","1879-260X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S0925443918304526/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063142549","display_name":"Pol Pic\u00f3n-Pag\u00e8s","orcid":"https://orcid.org/0000-0002-6471-3072","observed_orcids":["https://orcid.org/0000-0002-6471-3072"]},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Universitat Pompeu Fabra","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Pol Pic\u00f3n-Pag\u00e8s","raw_affiliation_strings":["Laboratory of Molecular Physiology, Faculty of Health and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Physiology, Faculty of Health and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain","institution_ids":["https://openalex.org/I170486558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088296874","display_name":"Joan Garcia-Buendia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Universitat Pompeu Fabra","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Joan Garcia-Buendia","raw_affiliation_strings":["Laboratory of Molecular Physiology, Faculty of Health and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Physiology, Faculty of Health and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain","institution_ids":["https://openalex.org/I170486558"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020881196","display_name":"Francisco J. Mu\u00f1oz","orcid":"https://orcid.org/0000-0002-1343-3599","observed_orcids":["https://orcid.org/0000-0002-1343-3599"]},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Universitat Pompeu Fabra","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Francisco J. Mu\u00f1oz","raw_affiliation_strings":["Laboratory of Molecular Physiology, Faculty of Health and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain. Electronic address: paco.munoz@upf.edu","Laboratory of Molecular Physiology, Faculty of Health and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Physiology, Faculty of Health and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain. Electronic address: paco.munoz@upf.edu","institution_ids":["https://openalex.org/I170486558"]},{"raw_affiliation_string":"Laboratory of Molecular Physiology, Faculty of Health and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain","institution_ids":["https://openalex.org/I170486558"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5020881196"],"corresponding_institution_ids":["https://openalex.org/I170486558"],"apc_list":{"value":4010,"currency":"USD","value_usd":4010},"apc_paid":{"value":4010,"currency":"USD","value_usd":4010},"fwci":2.296,"has_fulltext":true,"cited_by_count":367,"citation_normalized_percentile":{"value":0.90878828,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"1865","issue":"8","first_page":"1949","last_page":"1967"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.03280000016093254,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":1.0},{"id":"https://openalex.org/keywords/cerebral-blood-flow","display_name":"cerebral blood flow","score":0.8899999856948853},{"id":"https://openalex.org/keywords/intracellular-signaling","display_name":"intracellular signaling","score":0.7670000195503235},{"id":"https://openalex.org/keywords/s-nitrosylation","display_name":"S-nitrosylation","score":0.8529999852180481},{"id":"https://openalex.org/keywords/peroxynitrite","display_name":"peroxynitrite","score":0.9480000138282776},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.5600000023841858},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.8149999976158142},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9900000095367432},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.9940000176429749},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.35499998927116394}],"concepts":[{"id":"https://openalex.org/C2778784160","wikidata":"https://www.wikidata.org/wiki/Q419130","display_name":"Peroxynitrite","level":4,"score":0.8354811668395996},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.7695028781890869},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6378978490829468},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5374008417129517},{"id":"https://openalex.org/C2780795997","wikidata":"https://www.wikidata.org/wiki/Q413283","display_name":"Superoxide","level":3,"score":0.5075041651725769},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.48564067482948303},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.4548034369945526},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.4488789737224579},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.36799749732017517},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2898775637149811},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000073039","descriptor_name":"Nitrosative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D011499","descriptor_name":"Protein Processing, Post-Translational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030421","descriptor_name":"Peroxynitrous Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bbadis.2018.11.007","doi":"https://doi.org/10.1016/j.bbadis.2018.11.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbadis.2018.11.007","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0925443918304526/pdf","source":{"id":"https://openalex.org/S4210173099","display_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","issn_l":"0925-4439","issn":["0925-4439","1879-260X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","raw_type":"journal-article"},{"id":"pmid:30500433","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30500433","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta. Molecular basis of disease","raw_type":"Journal Article"},{"id":"pmh:oai:repositori.upf.edu:10230/45065","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10230/45065","pdf_url":null,"source":{"id":"https://openalex.org/S4306402615","display_name":"Repositori digital de la UPF (Universitat Pompeu Fabra)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170486558","host_organization_name":"Universitat Pompeu Fabra","host_organization_lineage":["https://openalex.org/I170486558"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.bbadis.2018.11.007","doi":"https://doi.org/10.1016/j.bbadis.2018.11.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbadis.2018.11.007","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0925443918304526/pdf","source":{"id":"https://openalex.org/S4210173099","display_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","issn_l":"0925-4439","issn":["0925-4439","1879-260X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2902321726.pdf","grobid_xml":"https://content.openalex.org/works/W2902321726.grobid-xml"},"referenced_works_count":353,"referenced_works":["https://openalex.org/W29116894","https://openalex.org/W58253119","https://openalex.org/W92910993","https://openalex.org/W127742586","https://openalex.org/W146469911","https://openalex.org/W163854267","https://openalex.org/W209919824","https://openalex.org/W1413391279","https://openalex.org/W1502551601","https://openalex.org/W1508660396","https://openalex.org/W1527671059","https://openalex.org/W1533021419","https://openalex.org/W1543601456","https://openalex.org/W1553004826","https://openalex.org/W1557074666","https://openalex.org/W1559895165","https://openalex.org/W1602807836","https://openalex.org/W1619234695","https://openalex.org/W1655404681","https://openalex.org/W1661336378","https://openalex.org/W1662308449","https://openalex.org/W1725300350","https://openalex.org/W1729010372","https://openalex.org/W1762207349","https://openalex.org/W1812961065","https://openalex.org/W1821918060","https://openalex.org/W1896970469","https://openalex.org/W1907994445","https://openalex.org/W1915631065","https://openalex.org/W1927541638","https://openalex.org/W1943358986","https://openalex.org/W1964371958","https://openalex.org/W1965268799","https://openalex.org/W1965447971","https://openalex.org/W1969309305","https://openalex.org/W1969489400","https://openalex.org/W1969545692","https://openalex.org/W1970184469","https://openalex.org/W1970199885","https://openalex.org/W1970205640","https://openalex.org/W1970840585","https://openalex.org/W1971005608","https://openalex.org/W1971532839","https://openalex.org/W1972910428","https://openalex.org/W1973817566","https://openalex.org/W1974184537","https://openalex.org/W1974829617","https://openalex.org/W1975270947","https://openalex.org/W1975676596","https://openalex.org/W1975881580","https://openalex.org/W1977623645","https://openalex.org/W1977956545","https://openalex.org/W1978220492","https://openalex.org/W1978601789","https://openalex.org/W1978644822","https://openalex.org/W1978839418","https://openalex.org/W1979864353","https://openalex.org/W1980906872","https://openalex.org/W1981024710","https://openalex.org/W1981755644","https://openalex.org/W1983588728","https://openalex.org/W1983623618","https://openalex.org/W1983761458","https://openalex.org/W1984135951","https://openalex.org/W1984248420","https://openalex.org/W1985221375","https://openalex.org/W1987004867","https://openalex.org/W1988392976","https://openalex.org/W1990350348","https://openalex.org/W1991347226","https://openalex.org/W1992725899","https://openalex.org/W1992888580","https://openalex.org/W1992890837","https://openalex.org/W1995191747","https://openalex.org/W1995377954","https://openalex.org/W1996562399","https://openalex.org/W1996902548","https://openalex.org/W1997395089","https://openalex.org/W1997652695","https://openalex.org/W1999262130","https://openalex.org/W1999357946","https://openalex.org/W1999649376","https://openalex.org/W1999921207","https://openalex.org/W2000075190","https://openalex.org/W2000887216","https://openalex.org/W2001422785","https://openalex.org/W2001658200","https://openalex.org/W2002192155","https://openalex.org/W2002311125","https://openalex.org/W2002344711","https://openalex.org/W2002946658","https://openalex.org/W2003471941","https://openalex.org/W2003666785","https://openalex.org/W2003804618","https://openalex.org/W2004079733","https://openalex.org/W2004690181","https://openalex.org/W2004813308","https://openalex.org/W2005208897","https://openalex.org/W2005706069","https://openalex.org/W2005839583","https://openalex.org/W2006659891","https://openalex.org/W2007232010","https://openalex.org/W2007737411","https://openalex.org/W2008825619","https://openalex.org/W2009013636","https://openalex.org/W2009279488","https://openalex.org/W2009313692","https://openalex.org/W2009556855","https://openalex.org/W2009601307","https://openalex.org/W2010226911","https://openalex.org/W2012219744","https://openalex.org/W2015400050","https://openalex.org/W2016031932","https://openalex.org/W2016356853","https://openalex.org/W2017770853","https://openalex.org/W2018200362","https://openalex.org/W2019107328","https://openalex.org/W2019421902","https://openalex.org/W2019814232","https://openalex.org/W2020361418","https://openalex.org/W2020914812","https://openalex.org/W2021386463","https://openalex.org/W2021624791","https://openalex.org/W2021727296","https://openalex.org/W2022628342","https://openalex.org/W2023164919","https://openalex.org/W2023200476","https://openalex.org/W2023216398","https://openalex.org/W2023421218","https://openalex.org/W2024674223","https://openalex.org/W2024746554","https://openalex.org/W2024862570","https://openalex.org/W2025145394","https://openalex.org/W2026406888","https://openalex.org/W2026865927","https://openalex.org/W2026908253","https://openalex.org/W2028120561","https://openalex.org/W2029887257","https://openalex.org/W2030345435","https://openalex.org/W2030356017","https://openalex.org/W2030496404","https://openalex.org/W2030567615","https://openalex.org/W2031636521","https://openalex.org/W2031681500","https://openalex.org/W2032067795","https://openalex.org/W2032092394","https://openalex.org/W2032992977","https://openalex.org/W2033852650","https://openalex.org/W2034587251","https://openalex.org/W2035139640","https://openalex.org/W2037672450","https://openalex.org/W2038179355","https://openalex.org/W2038624319","https://openalex.org/W2038897011","https://openalex.org/W2039626545","https://openalex.org/W2039640602","https://openalex.org/W2041034845","https://openalex.org/W2041753238","https://openalex.org/W2041934166","https://openalex.org/W2042853579","https://openalex.org/W2043024692","https://openalex.org/W2043340127","https://openalex.org/W2044259132","https://openalex.org/W2044622151","https://openalex.org/W2045352558","https://openalex.org/W2047076961","https://openalex.org/W2047819781","https://openalex.org/W2048111211","https://openalex.org/W2048473935","https://openalex.org/W2048719661","https://openalex.org/W2048768264","https://openalex.org/W2048849346","https://openalex.org/W2049046201","https://openalex.org/W2050607653","https://openalex.org/W2050609518","https://openalex.org/W2052048919","https://openalex.org/W2052216494","https://openalex.org/W2053128093","https://openalex.org/W2053925036","https://openalex.org/W2054240180","https://openalex.org/W2054336997","https://openalex.org/W2054729329","https://openalex.org/W2055502644","https://openalex.org/W2056181922","https://openalex.org/W2056585943","https://openalex.org/W2058137293","https://openalex.org/W2059071302","https://openalex.org/W2059379142","https://openalex.org/W2060545093","https://openalex.org/W2060802768","https://openalex.org/W2061382541","https://openalex.org/W2061995199","https://openalex.org/W2062325166","https://openalex.org/W2064871821","https://openalex.org/W2065949544","https://openalex.org/W2066116456","https://openalex.org/W2066143450","https://openalex.org/W2066621849","https://openalex.org/W2067195259","https://openalex.org/W2068301733","https://openalex.org/W2069055534","https://openalex.org/W2070068309","https://openalex.org/W2071164054","https://openalex.org/W2071953900","https://openalex.org/W2074759065","https://openalex.org/W2076474317","https://openalex.org/W2076796864","https://openalex.org/W2077106806","https://openalex.org/W2078002958","https://openalex.org/W2078786976","https://openalex.org/W2081529440","https://openalex.org/W2083338453","https://openalex.org/W2085035881","https://openalex.org/W2086405243","https://openalex.org/W2087106147","https://openalex.org/W2087166559","https://openalex.org/W2087969945","https://openalex.org/W2088269939","https://openalex.org/W2088323144","https://openalex.org/W2088683988","https://openalex.org/W2091473040","https://openalex.org/W2092478589","https://openalex.org/W2092880056","https://openalex.org/W2093573816","https://openalex.org/W2094038819","https://openalex.org/W2094054841","https://openalex.org/W2094697500","https://openalex.org/W2094745968","https://openalex.org/W2098272848","https://openalex.org/W2100973814","https://openalex.org/W2101077392","https://openalex.org/W2101457798","https://openalex.org/W2101967150","https://openalex.org/W2102117809","https://openalex.org/W2102133195","https://openalex.org/W2102368033","https://openalex.org/W2103465847","https://openalex.org/W2104194752","https://openalex.org/W2104847030","https://openalex.org/W2108699614","https://openalex.org/W2109078741","https://openalex.org/W2109727228","https://openalex.org/W2109835398","https://openalex.org/W2109893157","https://openalex.org/W2111589816","https://openalex.org/W2113665330","https://openalex.org/W2114120572","https://openalex.org/W2114435983","https://openalex.org/W2114881821","https://openalex.org/W2116137306","https://openalex.org/W2116835524","https://openalex.org/W2117036786","https://openalex.org/W2118008176","https://openalex.org/W2119082511","https://openalex.org/W2121459138","https://openalex.org/W2122214165","https://openalex.org/W2123403836","https://openalex.org/W2123546024","https://openalex.org/W2124018854","https://openalex.org/W2124703249","https://openalex.org/W2127689078","https://openalex.org/W2128708131","https://openalex.org/W2128963115","https://openalex.org/W2129009565","https://openalex.org/W2129174721","https://openalex.org/W2130265674","https://openalex.org/W2130877009","https://openalex.org/W2132704929","https://openalex.org/W2133019124","https://openalex.org/W2134369482","https://openalex.org/W2134785329","https://openalex.org/W2135069583","https://openalex.org/W2137381392","https://openalex.org/W2139337253","https://openalex.org/W2140299953","https://openalex.org/W2142474063","https://openalex.org/W2142975032","https://openalex.org/W2144102286","https://openalex.org/W2144109738","https://openalex.org/W2146432140","https://openalex.org/W2147569747","https://openalex.org/W2147993424","https://openalex.org/W2148491949","https://openalex.org/W2149307297","https://openalex.org/W2150166421","https://openalex.org/W2150722073","https://openalex.org/W2150999725","https://openalex.org/W2152494236","https://openalex.org/W2153373550","https://openalex.org/W2153555443","https://openalex.org/W2154661778","https://openalex.org/W2156102718","https://openalex.org/W2156992532","https://openalex.org/W2157665089","https://openalex.org/W2158135314","https://openalex.org/W2160610690","https://openalex.org/W2161949681","https://openalex.org/W2162611266","https://openalex.org/W2163790333","https://openalex.org/W2165646729","https://openalex.org/W2165840710","https://openalex.org/W2166314756","https://openalex.org/W2166342281","https://openalex.org/W2166559063","https://openalex.org/W2166577272","https://openalex.org/W2167886264","https://openalex.org/W2169118010","https://openalex.org/W2169182236","https://openalex.org/W2169303813","https://openalex.org/W2169401278","https://openalex.org/W2171216596","https://openalex.org/W2182130443","https://openalex.org/W2185085212","https://openalex.org/W2202133293","https://openalex.org/W2274552119","https://openalex.org/W2284066538","https://openalex.org/W2294615578","https://openalex.org/W2316025573","https://openalex.org/W2316190286","https://openalex.org/W2330666792","https://openalex.org/W2338347128","https://openalex.org/W2408597956","https://openalex.org/W2410082173","https://openalex.org/W2416588975","https://openalex.org/W2417841328","https://openalex.org/W2419265357","https://openalex.org/W2472322602","https://openalex.org/W2496845339","https://openalex.org/W2516716892","https://openalex.org/W2519226339","https://openalex.org/W2522941116","https://openalex.org/W2532911870","https://openalex.org/W2533432700","https://openalex.org/W2551436709","https://openalex.org/W2561810782","https://openalex.org/W2588733245","https://openalex.org/W2592371738","https://openalex.org/W2615543353","https://openalex.org/W2753576522","https://openalex.org/W2762082693","https://openalex.org/W2774024701","https://openalex.org/W2781808844","https://openalex.org/W2782358406","https://openalex.org/W2783983254","https://openalex.org/W2805440174","https://openalex.org/W2808465083","https://openalex.org/W2883270953","https://openalex.org/W2883611426","https://openalex.org/W4240619060","https://openalex.org/W4295994768","https://openalex.org/W6606646821","https://openalex.org/W6637150395","https://openalex.org/W6675123083"],"related_works":["https://openalex.org/W2171216596","https://openalex.org/W105208581","https://openalex.org/W2170927128","https://openalex.org/W7096991050","https://openalex.org/W2127783939","https://openalex.org/W2016422864","https://openalex.org/W2197855706","https://openalex.org/W2982147449","https://openalex.org/W72300352","https://openalex.org/W2167886264"],"abstract_inverted_index":{"Nitric":[0],"oxide":[1],"(NO)":[2],"works":[3],"as":[4,158],"a":[5,58],"retrograde":[6],"neurotransmitter":[7],"in":[8,20,23,46],"synapses,":[9],"allows":[10],"the":[11,26,29,34,49,52,66,74,96,106,114,118,126,130,142,145,150],"brain":[12],"blood":[13],"flow":[14],"and":[15,71,102,152],"also":[16,139],"has":[17],"important":[18],"roles":[19],"intracellular":[21],"signaling":[22],"neurons":[24],"from":[25],"regulation":[27],"of":[28,51,76,108,117,129,144,154],"neuronal":[30,97],"metabolic":[31],"status":[32],"to":[33,42,61,86,125,141,149],"dendritic":[35],"spine":[36],"growth.":[37],"Moreover":[38],"NO":[39,77],"is":[40,57,134],"able":[41],"perform":[43],"post-translational":[44],"modifications":[45],"proteins":[47,101,147],"by":[48],"S-nitrosylation":[50],"thiol":[53],"amino":[54],"acids,":[55],"which":[56],"physiological":[59,127],"mechanism":[60],"regulate":[62],"protein":[63],"function.":[64],"On":[65],"other":[67],"hand,":[68],"during":[69],"aging":[70],"pathological":[72],"processes":[73,156],"behavior":[75],"can":[78,92],"turn":[79],"harmful":[80],"when":[81],"reacts":[82,111],"with":[83,113],"superoxide":[84],"anion":[85],"form":[87],"peroxynitrite.":[88],"This":[89],"gaseous":[90],"compound":[91],"diffuse":[93],"easily":[94],"throughout":[95],"membranes":[98],"damaging":[99],"lipid,":[100],"nucleic":[103],"acids.":[104],"In":[105],"case":[107],"proteins,":[109],"peroxynitrite":[110],"mostly":[112],"phenolic":[115],"ring":[116],"tyrosines":[119],"forming":[120],"nitro-tyrosines":[121],"that":[122,138],"affects":[123],"dramatically":[124],"functions":[128],"proteins.":[131],"Protein":[132],"nitrotyrosination":[133],"an":[135],"irreversible":[136],"process":[137],"yields":[140],"accumulation":[143],"modified":[146],"contributing":[148],"onset":[151],"progression":[153],"neurodegenerative":[155],"such":[157],"Alzheimer's":[159],"disease":[160],"or":[161],"Parkinson's":[162],"disease.":[163]},"counts_by_year":[{"year":2026,"cited_by_count":34},{"year":2025,"cited_by_count":60},{"year":2024,"cited_by_count":63},{"year":2023,"cited_by_count":72},{"year":2022,"cited_by_count":64},{"year":2021,"cited_by_count":41},{"year":2020,"cited_by_count":26},{"year":2019,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-12-11T00:00:00"}
