{"id":"https://openalex.org/W2902300699","doi":"https://doi.org/10.1111/sdi.12765","title":"ESRD patients coinfected with human immunodeficiency virus and Hepatitis C: Outcomes and management challenges","display_name":"ESRD patients coinfected with human immunodeficiency virus and Hepatitis C: Outcomes and management challenges","publication_year":2018,"publication_date":"2018-11-26","ids":{"openalex":"https://openalex.org/W2902300699","doi":"https://doi.org/10.1111/sdi.12765","mag":"2902300699","pmid":"https://pubmed.ncbi.nlm.nih.gov/30475425","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6397779"},"language":"en","primary_location":{"id":"doi:10.1111/sdi.12765","doi":"https://doi.org/10.1111/sdi.12765","is_oa":false,"landing_page_url":"https://doi.org/10.1111/sdi.12765","pdf_url":null,"source":{"id":"https://openalex.org/S34122167","display_name":"Seminars in Dialysis","issn_l":"0894-0959","issn":["0894-0959","1525-139X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Dialysis","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6397779","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036989582","display_name":"Deirdre L. Sawinski","orcid":"https://orcid.org/0000-0001-7903-8295","observed_orcids":["https://orcid.org/0000-0001-7903-8295"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Deirdre Sawinski","raw_affiliation_strings":["Renal, Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Renal, Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5036989582"],"corresponding_institution_ids":["https://openalex.org/I79576946"],"apc_list":{"value":3730,"currency":"USD","value_usd":3730},"apc_paid":null,"fwci":0.1017,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.1535682,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"32","issue":"2","first_page":"159","last_page":"168"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.9398999810218811,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.9398999810218811,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.009600000455975533,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-hcv-coinfection","display_name":"HIV/HCV coinfection","score":0.9599999785423279},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.9729999899864197},{"id":"https://openalex.org/keywords/chronic-kidney-disease-progression","display_name":"chronic kidney disease progression","score":0.7760000228881836},{"id":"https://openalex.org/keywords/dialysis-survival","display_name":"dialysis survival","score":0.9869999885559082},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.8980000019073486},{"id":"https://openalex.org/keywords/post-transplant-outcomes","display_name":"post-transplant outcomes","score":0.8840000033378601},{"id":"https://openalex.org/keywords/direct-acting-antivirals","display_name":"direct-acting antivirals","score":0.9319999814033508},{"id":"https://openalex.org/keywords/drug-drug-interactions","display_name":"drug-drug interactions","score":0.9760000109672546},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.9789999723434448},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.906000018119812}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9519676566123962},{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.7548449039459229},{"id":"https://openalex.org/C2776455275","wikidata":"https://www.wikidata.org/wiki/Q154869","display_name":"Hepatitis C","level":2,"score":0.6662715673446655},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.6298068761825562},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.5800963044166565},{"id":"https://openalex.org/C2776408679","wikidata":"https://www.wikidata.org/wiki/Q708693","display_name":"Hepatitis C virus","level":3,"score":0.5791184902191162},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5165306925773621},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.48753854632377625},{"id":"https://openalex.org/C2780303639","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplantation","level":3,"score":0.46363064646720886},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4494749903678894},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4445981979370117},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.4358018636703491},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.40609055757522583},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38029587268829346},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.20733696222305298},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006435","descriptor_name":"Renal Dialysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006526","descriptor_name":"Hepatitis C","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006526","descriptor_name":"Hepatitis C","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060085","descriptor_name":"Coinfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1111/sdi.12765","doi":"https://doi.org/10.1111/sdi.12765","is_oa":false,"landing_page_url":"https://doi.org/10.1111/sdi.12765","pdf_url":null,"source":{"id":"https://openalex.org/S34122167","display_name":"Seminars in Dialysis","issn_l":"0894-0959","issn":["0894-0959","1525-139X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Dialysis","raw_type":"journal-article"},{"id":"pmid:30475425","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30475425","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in dialysis","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5990064","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6397779","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6397779","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6397779","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Semin Dial","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5990064","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6397779","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4241626052","display_name":"Waiting List and Kidney Transplant Outcomes for Patients with Hepatitis C Infection","funder_award_id":"R21DK108045","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W1621802947","https://openalex.org/W1908153784","https://openalex.org/W1931928567","https://openalex.org/W1969562548","https://openalex.org/W1980154502","https://openalex.org/W1985439784","https://openalex.org/W1987060364","https://openalex.org/W1992668008","https://openalex.org/W1994433902","https://openalex.org/W2001020842","https://openalex.org/W2008923632","https://openalex.org/W2012908156","https://openalex.org/W2026809179","https://openalex.org/W2027498662","https://openalex.org/W2036313720","https://openalex.org/W2036681665","https://openalex.org/W2047156711","https://openalex.org/W2049747948","https://openalex.org/W2053270578","https://openalex.org/W2056129529","https://openalex.org/W2056725789","https://openalex.org/W2062563125","https://openalex.org/W2073076709","https://openalex.org/W2091955447","https://openalex.org/W2093267614","https://openalex.org/W2102951977","https://openalex.org/W2104153029","https://openalex.org/W2110195764","https://openalex.org/W2111051799","https://openalex.org/W2116328240","https://openalex.org/W2124892937","https://openalex.org/W2135899950","https://openalex.org/W2138339906","https://openalex.org/W2144013298","https://openalex.org/W2147020182","https://openalex.org/W2148325695","https://openalex.org/W2154479838","https://openalex.org/W2159961241","https://openalex.org/W2161668598","https://openalex.org/W2195057080","https://openalex.org/W2296452901","https://openalex.org/W2337582323","https://openalex.org/W2338759514","https://openalex.org/W2344572331","https://openalex.org/W2345565222","https://openalex.org/W2491722838","https://openalex.org/W2512371825","https://openalex.org/W2519498039","https://openalex.org/W2559030202","https://openalex.org/W2605200881","https://openalex.org/W2625077955","https://openalex.org/W2734895186","https://openalex.org/W2745433279","https://openalex.org/W2761085897","https://openalex.org/W2766148669","https://openalex.org/W2791786965","https://openalex.org/W2799552858","https://openalex.org/W2811268849","https://openalex.org/W4240023758"],"related_works":["https://openalex.org/W1989144251","https://openalex.org/W2766148669","https://openalex.org/W2922016345","https://openalex.org/W2036957570","https://openalex.org/W2751460966","https://openalex.org/W2997791083","https://openalex.org/W1992027207","https://openalex.org/W2791528047","https://openalex.org/W2056058596","https://openalex.org/W614554741"],"abstract_inverted_index":{"HIV":[0,76],"infection":[1,77],"is":[2,46],"a":[3,60],"major":[4],"public":[5],"health":[6],"problem":[7],"worldwide.":[8],"Due":[9],"to":[10,38,40,73,87],"shared":[11],"modes":[12],"of":[13,30],"acquisition,":[14],"many":[15],"HIV+":[16],"patients":[17,25,74],"are":[18,35,70,93],"coinfected":[19,24,50],"with":[20,75],"Hepatitis":[21],"C.":[22],"HIV/HCV":[23],"have":[26],"an":[27,85],"increased":[28],"burden":[29],"chronic":[31],"kidney":[32],"disease":[33],"and":[34,105],"more":[36],"likely":[37],"progress":[39],"end-stage":[41],"renal":[42],"disease.":[43],"Dialysis":[44],"survival":[45,61],"diminished":[47],"in":[48,53],"the":[49,54,98,108],"population,":[51],"even":[52],"contemporary":[55],"era.":[56],"Kidney":[57],"transplantation":[58],"offers":[59],"benefit":[62],"over":[63],"remaining":[64],"on":[65],"dialysis;":[66],"however,":[67],"posttransplant":[68],"outcomes":[69],"inferior":[71],"compared":[72],"alone.":[78],"Direct":[79],"acting":[80,100],"antiviral":[81,101],"agents":[82],"may":[83],"offer":[84],"opportunity":[86],"improve":[88],"patient":[89],"survival,":[90],"but":[91],"there":[92],"significant":[94],"drug-drug":[95],"interactions":[96],"involving":[97],"direct":[99],"agents,":[102],"antiretroviral":[103],"therapy,":[104],"immunosuppression":[106],"that":[107],"clinician":[109],"should":[110],"be":[111],"aware":[112],"of.":[113]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-12-11T00:00:00"}