{"id":"https://openalex.org/W2902129641","doi":"https://doi.org/10.3892/mmr.2018.9725","title":"MicroRNA\u2011146a inhibits the inflammatory responses induced by interleukin\u201117A during the infection of Helicobacter pylori","display_name":"MicroRNA\u2011146a inhibits the inflammatory responses induced by interleukin\u201117A during the infection of Helicobacter pylori","publication_year":2018,"publication_date":"2018-12-05","ids":{"openalex":"https://openalex.org/W2902129641","doi":"https://doi.org/10.3892/mmr.2018.9725","mag":"2902129641","pmid":"https://pubmed.ncbi.nlm.nih.gov/30535468"},"language":"en","primary_location":{"id":"doi:10.3892/mmr.2018.9725","doi":"https://doi.org/10.3892/mmr.2018.9725","is_oa":true,"landing_page_url":"https://doi.org/10.3892/mmr.2018.9725","pdf_url":"http://www.spandidos-publications.com/10.3892/mmr.2018.9725/download","source":{"id":"https://openalex.org/S95395365","display_name":"Molecular Medicine Reports","issn_l":"1791-2997","issn":["1791-2997","1791-3004"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","medline","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Medicine Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.spandidos-publications.com/10.3892/mmr.2018.9725/download","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100368136","display_name":"Na Li","orcid":"https://orcid.org/0000-0002-6227-8433","observed_orcids":["https://orcid.org/0000-0002-6227-8433"]},"institutions":[{"id":"https://openalex.org/I4210157767","display_name":"Jinan Military General Hospital","ror":"https://ror.org/05chjan92","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210157767"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Na Li","raw_affiliation_strings":["Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China","institution_ids":["https://openalex.org/I4210157767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100666570","display_name":"Jianlong Wang","orcid":"https://orcid.org/0000-0002-1317-6457","observed_orcids":["https://orcid.org/0000-0002-1317-6457","https://orcid.org/0000-0003-4667-9365"]},"institutions":[{"id":"https://openalex.org/I4210136826","display_name":"Jining First People's Hospital","ror":"https://ror.org/04gs6v336","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210136826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianlong Wang","raw_affiliation_strings":["Department of Pediatrics, The First People's Hospital of Jining, Jining, Shandong 272000, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, The First People's Hospital of Jining, Jining, Shandong 272000, P.R. China","institution_ids":["https://openalex.org/I4210136826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029864351","display_name":"Wenqian Yu","orcid":"https://orcid.org/0009-0007-5410-4015","observed_orcids":["https://orcid.org/0009-0007-5410-4015"]},"institutions":[{"id":"https://openalex.org/I4210157767","display_name":"Jinan Military General Hospital","ror":"https://ror.org/05chjan92","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210157767"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenqian Yu","raw_affiliation_strings":["Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China","institution_ids":["https://openalex.org/I4210157767"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kai Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157767","display_name":"Jinan Military General Hospital","ror":"https://ror.org/05chjan92","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210157767"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kai Dong","raw_affiliation_strings":["Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China","institution_ids":["https://openalex.org/I4210157767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100569380","display_name":"You Feng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157767","display_name":"Jinan Military General Hospital","ror":"https://ror.org/05chjan92","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210157767"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feng You","raw_affiliation_strings":["Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China","institution_ids":["https://openalex.org/I4210157767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025290474","display_name":"Biao Si","orcid":"https://orcid.org/0009-0007-4966-0965","observed_orcids":["https://orcid.org/0009-0007-4966-0965"]},"institutions":[{"id":"https://openalex.org/I4210157767","display_name":"Jinan Military General Hospital","ror":"https://ror.org/05chjan92","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210157767"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Biao Si","raw_affiliation_strings":["Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China","institution_ids":["https://openalex.org/I4210157767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101576245","display_name":"Bin Tang","orcid":"https://orcid.org/0000-0002-1762-3883","observed_orcids":["https://orcid.org/0000-0002-1762-3883"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]},{"id":"https://openalex.org/I4210131174","display_name":"Southwest Hospital","ror":"https://ror.org/02jn36537","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131174"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Tang","raw_affiliation_strings":["Department of Clinical Microbiology and Immunology, Southwest Hospital and College of Medical Laboratory Science, The Third Military Medical University, Chongqing, Sichuan 400038, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Microbiology and Immunology, Southwest Hospital and College of Medical Laboratory Science, The Third Military Medical University, Chongqing, Sichuan 400038, P.R. China","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210131174"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100456457","display_name":"Yan Zhang","orcid":"https://orcid.org/0009-0005-7322-7809","observed_orcids":["https://orcid.org/0009-0005-7322-7809"]},"institutions":[{"id":"https://openalex.org/I4210157767","display_name":"Jinan Military General Hospital","ror":"https://ror.org/05chjan92","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210157767"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Zhang","raw_affiliation_strings":["Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China","institution_ids":["https://openalex.org/I4210157767"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tongjian Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157767","display_name":"Jinan Military General Hospital","ror":"https://ror.org/05chjan92","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210157767"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tongjian Wang","raw_affiliation_strings":["Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China","institution_ids":["https://openalex.org/I4210157767"]}]},{"author_position":"last","author":{"id":null,"display_name":"Bin Qiao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157767","display_name":"Jinan Military General Hospital","ror":"https://ror.org/05chjan92","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210157767"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Qiao","raw_affiliation_strings":["Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cardiovascular Disease, The 960th Hospital of Chinese PLA, Jinan, Shandong 250022, P.R. China","institution_ids":["https://openalex.org/I4210157767"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.0794,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.86801399,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"19","issue":"2","first_page":"1388","last_page":"1395"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.08009999990463257,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microrna-146a","display_name":"microRNA-146a","score":0.9240000247955322},{"id":"https://openalex.org/keywords/il-17a","display_name":"IL-17A","score":0.996999979019165},{"id":"https://openalex.org/keywords/helicobacter-pylori-infection","display_name":"Helicobacter pylori infection","score":0.9959999918937683},{"id":"https://openalex.org/keywords/gastritis","display_name":"gastritis","score":0.7599999904632568},{"id":"https://openalex.org/keywords/irak1","display_name":"IRAK1","score":0.9509999752044678},{"id":"https://openalex.org/keywords/traf6","display_name":"TRAF6","score":1.0},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.9750000238418579},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.5339999794960022},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.8899999856948853}],"concepts":[{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.6397978067398071},{"id":"https://openalex.org/C47348012","wikidata":"https://www.wikidata.org/wiki/Q99486570","display_name":"Interleukin 17","level":3,"score":0.6012895107269287},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5974608659744263},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.5617886781692505},{"id":"https://openalex.org/C2781443798","wikidata":"https://www.wikidata.org/wiki/Q383249","display_name":"Gastric mucosa","level":3,"score":0.5483300685882568},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5415686368942261},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.5381444692611694},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5379493832588196},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.5193875432014465},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.5043741464614868},{"id":"https://openalex.org/C74172505","wikidata":"https://www.wikidata.org/wiki/Q194908","display_name":"Interleukin","level":3,"score":0.4984922409057617},{"id":"https://openalex.org/C2780832600","wikidata":"https://www.wikidata.org/wiki/Q134684","display_name":"Helicobacter","level":3,"score":0.4608002007007599},{"id":"https://openalex.org/C2781018059","wikidata":"https://www.wikidata.org/wiki/Q207609","display_name":"Oncogene","level":4,"score":0.4476878345012665},{"id":"https://openalex.org/C2780561475","wikidata":"https://www.wikidata.org/wiki/Q183130","display_name":"Chronic gastritis","level":4,"score":0.4448888301849365},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4345550239086151},{"id":"https://openalex.org/C2778677798","wikidata":"https://www.wikidata.org/wiki/Q183130","display_name":"Gastritis","level":3,"score":0.40699756145477295},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3706604540348053},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.24242573976516724},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.21056285500526428},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.17269879579544067},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06880328059196472},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D005756","descriptor_name":"Gastritis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005756","descriptor_name":"Gastritis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D020381","descriptor_name":"Interleukin-17","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048029","descriptor_name":"TNF Receptor-Associated Factor 6","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053727","descriptor_name":"Interleukin-18 Receptor alpha Subunit","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3892/mmr.2018.9725","doi":"https://doi.org/10.3892/mmr.2018.9725","is_oa":true,"landing_page_url":"https://doi.org/10.3892/mmr.2018.9725","pdf_url":"http://www.spandidos-publications.com/10.3892/mmr.2018.9725/download","source":{"id":"https://openalex.org/S95395365","display_name":"Molecular Medicine Reports","issn_l":"1791-2997","issn":["1791-2997","1791-3004"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","medline","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Medicine Reports","raw_type":"journal-article"},{"id":"pmid:30535468","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30535468","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular medicine reports","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3892/mmr.2018.9725","doi":"https://doi.org/10.3892/mmr.2018.9725","is_oa":true,"landing_page_url":"https://doi.org/10.3892/mmr.2018.9725","pdf_url":"http://www.spandidos-publications.com/10.3892/mmr.2018.9725/download","source":{"id":"https://openalex.org/S95395365","display_name":"Molecular Medicine Reports","issn_l":"1791-2997","issn":["1791-2997","1791-3004"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","medline","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Medicine Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2902129641.pdf","grobid_xml":"https://content.openalex.org/works/W2902129641.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W1539144750","https://openalex.org/W1555961633","https://openalex.org/W1935309503","https://openalex.org/W1959664751","https://openalex.org/W1965727091","https://openalex.org/W1983135466","https://openalex.org/W1983899969","https://openalex.org/W1984343774","https://openalex.org/W1994246752","https://openalex.org/W2003877633","https://openalex.org/W2004432444","https://openalex.org/W2009357867","https://openalex.org/W2013270187","https://openalex.org/W2016466834","https://openalex.org/W2022477030","https://openalex.org/W2033459613","https://openalex.org/W2036281114","https://openalex.org/W2041322441","https://openalex.org/W2045881743","https://openalex.org/W2050165541","https://openalex.org/W2055211034","https://openalex.org/W2062903634","https://openalex.org/W2075860675","https://openalex.org/W2077360946","https://openalex.org/W2078336838","https://openalex.org/W2084037169","https://openalex.org/W2084706275","https://openalex.org/W2093897672","https://openalex.org/W2095558248","https://openalex.org/W2101619948","https://openalex.org/W2102914855","https://openalex.org/W2107277218","https://openalex.org/W2119513012","https://openalex.org/W2124635565","https://openalex.org/W2133613657","https://openalex.org/W2136357996","https://openalex.org/W2142316043","https://openalex.org/W2143107875","https://openalex.org/W2149880936","https://openalex.org/W2152172142","https://openalex.org/W2165769226","https://openalex.org/W2171398182","https://openalex.org/W2176271034","https://openalex.org/W2466911043","https://openalex.org/W2743743412","https://openalex.org/W6684006375"],"related_works":["https://openalex.org/W1984343774","https://openalex.org/W2036281114","https://openalex.org/W2387235940","https://openalex.org/W3143082716","https://openalex.org/W2778555666","https://openalex.org/W3087809997","https://openalex.org/W2132994460","https://openalex.org/W3128155395","https://openalex.org/W2130862272","https://openalex.org/W1989045814"],"abstract_inverted_index":{"Helicobacter":[0],"pylori":[1,24,64,197,216],"(H.":[2],"pylori)":[3],"infection":[4,25,82,213],"is":[5,20],"the":[6,27,31,35,62,72,77,91,98,116,148,171,175,185,208,212,223],"major":[7],"cause":[8],"of":[9,18,37,55,74,79,94,119,130,144,151,177,214,225],"chronic":[10],"active":[11],"gastritis":[12,45,254],"and":[13,58,103,157,170,179,189,227],"peptic":[14],"ulcer":[15],"disease.":[16],"Upregulation":[17],"IL\u201117A":[19,75,126,166,190,228],"associated":[21,60],"with":[22,61,83,195,237],"H.":[23,43,63,84,196,215,238],"in":[26,34,42,101,104,121,137,191,217,232,253],"gastric":[28,122,193,234],"mucosa;":[29],"however,":[30],"factors":[32],"involved":[33],"regulation":[36],"interleukin":[38],"(IL)\u201117A\u2011induced":[39],"inflammatory":[40,99,135,209],"responses":[41,136],"pylori\u2011associated":[44],"remain":[46],"unknown.":[47],"MicroRNAs":[48],"(miRNAs)":[49],"serve":[50,246],"as":[51,86,88,247],"key":[52],"post\u2011transcriptional":[53],"regulators":[54],"gene":[56],"expression":[57,78,117,149,224],"are":[59,229],"infection.":[65],"The":[66,128,142,200],"present":[67],"study":[68],"aimed":[69],"to":[70,89,114],"analyze":[71],"effects":[73,129,143],"on":[76,97,133,147],"miR\u2011146a":[80,95,120,131,145,188,205,226,244],"upon":[81,125,165],"pylori,":[85],"well":[87],"identify":[90],"possible":[92],"impact":[93],"dysregulation":[96],"response":[100,210],"vivo":[102],"vitro.":[105],"Reverse":[106],"transcription\u2011quantitative":[107],"polymerase":[108],"chain":[109],"reaction":[110],"analysis":[111],"was":[112,181,198],"used":[113],"determine":[115],"levels":[118,150],"epithelial":[123],"cells":[124,139],"stimulation.":[127],"mimics":[132,146],"IL\u201117A\u2011induced":[134,204],"SGC\u20117901":[138],"were":[140,168],"evaluated.":[141],"IL\u20111":[152],"receptor\u2011associated":[153,161],"kinase":[154],"1":[155],"(IRAK1)":[156],"tumor":[158],"necrosis":[159],"factor":[160,162],"6":[163],"(TRAF6)":[164],"treatment":[167],"analyzed,":[169],"IL\u201117A\u2011stimulated":[172],"inflammation":[173],"following":[174],"silencing":[176],"IRAK1":[178],"TRAF6":[180],"observed.":[182],"In":[183],"addition,":[184],"correlation":[186],"between":[187],"human":[192,233],"mucosa":[194,235],"examined.":[199],"results":[201],"indicated":[202],"that":[203,243],"may":[206,245],"regulate":[207],"during":[211],"a":[218,248],"nuclear":[219],"factor\u2011\u03baB\u2011dependent":[220],"manner.":[221],"Furthermore,":[222],"positively":[230],"correlated":[231],"infected":[236],"pylori.":[239],"These":[240],"data":[241],"suggested":[242],"biomarker":[249],"or":[250],"therapeutic":[251],"target":[252],"therapy.":[255]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-12-11T00:00:00"}