{"id":"https://openalex.org/W2901740501","doi":"https://doi.org/10.1016/j.molimm.2018.11.003","title":"Protective effect of ginsenoside Rg1 on LPS-induced apoptosis of lung epithelial cells","display_name":"Protective effect of ginsenoside Rg1 on LPS-induced apoptosis of lung epithelial cells","publication_year":2018,"publication_date":"2018-11-22","ids":{"openalex":"https://openalex.org/W2901740501","doi":"https://doi.org/10.1016/j.molimm.2018.11.003","mag":"2901740501","pmid":"https://pubmed.ncbi.nlm.nih.gov/30471963"},"language":"en","primary_location":{"id":"doi:10.1016/j.molimm.2018.11.003","doi":"https://doi.org/10.1016/j.molimm.2018.11.003","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molimm.2018.11.003","pdf_url":null,"source":{"id":"https://openalex.org/S92126311","display_name":"Molecular Immunology","issn_l":"0161-5890","issn":["0161-5890","1872-9142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056062849","display_name":"Qijian Ji","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799773085","display_name":"Nanjing General Hospital of Nanjing Military Command","ror":"https://ror.org/04kmpyd03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2799773085"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qijian Ji","raw_affiliation_strings":["Department of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210002, PR China; Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China; Department of Critical Care Medicine, Xuyi People's hospital, xuyi, 211700, Jiangsu, PR China. Electronic address: jiqj_nj@sina.com","Department of Critical Care Medicine, Xuyi People's hospital, xuyi, 211700, Jiangsu, PR China","Department of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210002, PR China","Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210002, PR China; Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China; Department of Critical Care Medicine, Xuyi People's hospital, xuyi, 211700, Jiangsu, PR China. Electronic address: jiqj_nj@sina.com","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I83519826","https://openalex.org/I881766915"]},{"raw_affiliation_string":"Department of Critical Care Medicine, Xuyi People's hospital, xuyi, 211700, Jiangsu, PR China","institution_ids":[]},{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210002, PR China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025284547","display_name":"Zhaorui Sun","orcid":"https://orcid.org/0000-0002-8969-498X","observed_orcids":["https://orcid.org/0000-0002-8969-498X"]},"institutions":[{"id":"https://openalex.org/I2799773085","display_name":"Nanjing General Hospital of Nanjing Military Command","ror":"https://ror.org/04kmpyd03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2799773085"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhaorui Sun","raw_affiliation_strings":["Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: sunzhr84@163.com","Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: sunzhr84@163.com","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]},{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100306137","display_name":"Zhizhou Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799773085","display_name":"Nanjing General Hospital of Nanjing Military Command","ror":"https://ror.org/04kmpyd03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2799773085"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhizhou Yang","raw_affiliation_strings":["Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: yangzz_nj@sina.com","Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: yangzz_nj@sina.com","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]},{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100740311","display_name":"Wei Zhang","orcid":"https://orcid.org/0000-0002-6508-364X","observed_orcids":["https://orcid.org/0000-0002-6508-364X","https://orcid.org/0000-0003-0241-5851","https://orcid.org/0000-0001-6229-8111"]},"institutions":[{"id":"https://openalex.org/I2799773085","display_name":"Nanjing General Hospital of Nanjing Military Command","ror":"https://ror.org/04kmpyd03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2799773085"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Zhang","raw_affiliation_strings":["Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: zhangwei80_nj@sina.com","Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: zhangwei80_nj@sina.com","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]},{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101915520","display_name":"Yi Ren","orcid":"https://orcid.org/0009-0002-8778-5586","observed_orcids":["https://orcid.org/0009-0002-8778-5586"]},"institutions":[{"id":"https://openalex.org/I2799773085","display_name":"Nanjing General Hospital of Nanjing Military Command","ror":"https://ror.org/04kmpyd03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2799773085"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Ren","raw_affiliation_strings":["Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: renyi_nj@sina.com","Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: renyi_nj@sina.com","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]},{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076097741","display_name":"Weijun Chen","orcid":"https://orcid.org/0000-0002-1260-3488","observed_orcids":["https://orcid.org/0000-0002-1260-3488"]},"institutions":[{"id":"https://openalex.org/I2799773085","display_name":"Nanjing General Hospital of Nanjing Military Command","ror":"https://ror.org/04kmpyd03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2799773085"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weijun Chen","raw_affiliation_strings":["Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: chenwj_nj@sina.com","Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: chenwj_nj@sina.com","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]},{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070434892","display_name":"Mengya Yao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799773085","display_name":"Nanjing General Hospital of Nanjing Military Command","ror":"https://ror.org/04kmpyd03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2799773085"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengya Yao","raw_affiliation_strings":["Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: yaomy_nj@sina.com","Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: yaomy_nj@sina.com","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]},{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101751192","display_name":"Shinan Nie","orcid":"https://orcid.org/0000-0002-9989-4766","observed_orcids":["https://orcid.org/0000-0002-9989-4766"]},"institutions":[{"id":"https://openalex.org/I2799773085","display_name":"Nanjing General Hospital of Nanjing Military Command","ror":"https://ror.org/04kmpyd03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2799773085"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shinan Nie","raw_affiliation_strings":["Department of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210002, PR China; Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: shn_nie@sina.com","Department of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210002, PR China","Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China"],"raw_orcid":"https://orcid.org/0000-0002-9989-4766","affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210002, PR China; Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China. Electronic address: shn_nie@sina.com","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I83519826","https://openalex.org/I881766915"]},{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210002, PR China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR China","institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I881766915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5025284547","https://openalex.org/A5101751192"],"corresponding_institution_ids":["https://openalex.org/I2799773085","https://openalex.org/I83519826","https://openalex.org/I881766915"],"apc_list":{"value":3340,"currency":"USD","value_usd":3340},"apc_paid":null,"fwci":2.6429,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.87837838,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":98},"biblio":{"volume":"136","issue":null,"first_page":"168","last_page":"174"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11889","display_name":"Ginseng Biological Effects and Applications","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11889","display_name":"Ginseng Biological Effects and Applications","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11332","display_name":"Genomics, phytochemicals, and oxidative stress","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ginsenoside-rg1","display_name":"ginsenoside Rg1","score":1.0},{"id":"https://openalex.org/keywords/sepsis-induced-acute-lung-injury","display_name":"sepsis-induced acute lung injury","score":0.9089999794960022},{"id":"https://openalex.org/keywords/lipopolysaccharide","display_name":"lipopolysaccharide","score":0.9290000200271606},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.8759999871253967},{"id":"https://openalex.org/keywords/autophagy","display_name":"autophagy","score":0.9940000176429749},{"id":"https://openalex.org/keywords/nrf2","display_name":"Nrf2","score":0.8820000290870667},{"id":"https://openalex.org/keywords/nf-kappab-p65-phosphorylation","display_name":"p65 phosphorylation","score":0.7979999780654907},{"id":"https://openalex.org/keywords/lung-epithelial-cells","display_name":"lung epithelial cells","score":0.8840000033378601},{"id":"https://openalex.org/keywords/mle-12-cells","display_name":"MLE-12 cells","score":0.9750000238418579},{"id":"https://openalex.org/keywords/3-methyladenine","display_name":"3-methyladenine","score":0.8669999837875366},{"id":"https://openalex.org/keywords/rapamycin","display_name":"rapamycin","score":0.8619999885559082}],"concepts":[{"id":"https://openalex.org/C203522944","wikidata":"https://www.wikidata.org/wiki/Q288322","display_name":"Autophagy","level":3,"score":0.9479603171348572},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.8562434315681458},{"id":"https://openalex.org/C2910036229","wikidata":"https://www.wikidata.org/wiki/Q59662497","display_name":"Ginsenoside Rg1","level":5,"score":0.8238005638122559},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5771225690841675},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5386770367622375},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.481062650680542},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.46405306458473206},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.45695000886917114},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.44812294840812683},{"id":"https://openalex.org/C2776539398","wikidata":"https://www.wikidata.org/wiki/Q59662497","display_name":"Ginsenoside","level":4,"score":0.4212225675582886},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.42117607593536377},{"id":"https://openalex.org/C2778754761","wikidata":"https://www.wikidata.org/wiki/Q421804","display_name":"Lipopolysaccharide","level":2,"score":0.4126773774623871},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3995652198791504},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3613940477371216},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.31628182530403137},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30998122692108154},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.07458972930908203},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06378284096717834},{"id":"https://openalex.org/C2779232237","wikidata":"https://www.wikidata.org/wiki/Q20817212","display_name":"Ginseng","level":3,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001343","descriptor_name":"Autophagy","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001343","descriptor_name":"Autophagy","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002491","descriptor_name":"Central Nervous System Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020123","descriptor_name":"Sirolimus","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D020545","descriptor_name":"Respiratory Mucosa","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D036145","descriptor_name":"Ginsenosides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051267","descriptor_name":"NF-E2-Related Factor 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051996","descriptor_name":"Transcription Factor RelA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D055371","descriptor_name":"Acute Lung Injury","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D055371","descriptor_name":"Acute Lung Injury","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.molimm.2018.11.003","doi":"https://doi.org/10.1016/j.molimm.2018.11.003","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molimm.2018.11.003","pdf_url":null,"source":{"id":"https://openalex.org/S92126311","display_name":"Molecular Immunology","issn_l":"0161-5890","issn":["0161-5890","1872-9142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Immunology","raw_type":"journal-article"},{"id":"pmid:30471963","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30471963","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3743475364","display_name":null,"funder_award_id":"81701894","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3750749629","display_name":null,"funder_award_id":"QNRC2016908","funder_id":"https://openalex.org/F4320327778","funder_display_name":"Jiangsu Provincial Medical Youth Talent"},{"id":"https://openalex.org/G4351159806","display_name":null,"funder_award_id":"81401583","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8192395711","display_name":null,"funder_award_id":"QNRC2016909","funder_id":"https://openalex.org/F4320327778","funder_display_name":"Jiangsu Provincial Medical Youth Talent"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320327778","display_name":"Jiangsu Provincial Medical Youth Talent","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W258634877","https://openalex.org/W1526339950","https://openalex.org/W1823772832","https://openalex.org/W1937948046","https://openalex.org/W1967665698","https://openalex.org/W1973884972","https://openalex.org/W2000017694","https://openalex.org/W2005759082","https://openalex.org/W2016040396","https://openalex.org/W2021049193","https://openalex.org/W2023598683","https://openalex.org/W2025971851","https://openalex.org/W2032955209","https://openalex.org/W2034822799","https://openalex.org/W2035230711","https://openalex.org/W2052771537","https://openalex.org/W2063919294","https://openalex.org/W2076062022","https://openalex.org/W2081057817","https://openalex.org/W2086082990","https://openalex.org/W2093852073","https://openalex.org/W2101297553","https://openalex.org/W2113010696","https://openalex.org/W2126934086","https://openalex.org/W2134220633","https://openalex.org/W2139458682","https://openalex.org/W2141327444","https://openalex.org/W2141736687","https://openalex.org/W2143505648","https://openalex.org/W2148701132","https://openalex.org/W2151426785","https://openalex.org/W2155383113","https://openalex.org/W2161328469","https://openalex.org/W2164778558","https://openalex.org/W2164990391","https://openalex.org/W2266938879","https://openalex.org/W2386850217","https://openalex.org/W2406276169","https://openalex.org/W2489429340","https://openalex.org/W2494626312","https://openalex.org/W2503715122","https://openalex.org/W2505024819","https://openalex.org/W2539939673","https://openalex.org/W2559772198","https://openalex.org/W2581766282","https://openalex.org/W2605029040","https://openalex.org/W2768545959","https://openalex.org/W2983727052","https://openalex.org/W2984641466","https://openalex.org/W3146260035","https://openalex.org/W4294658238","https://openalex.org/W6745826549","https://openalex.org/W6769825548"],"related_works":["https://openalex.org/W2998400536","https://openalex.org/W2932638633","https://openalex.org/W7124833339","https://openalex.org/W4394804837","https://openalex.org/W766831234","https://openalex.org/W4383480724","https://openalex.org/W2905885264","https://openalex.org/W4400523184","https://openalex.org/W4317815041","https://openalex.org/W7208731692"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-11-29T00:00:00"}