{"id":"https://openalex.org/W2901257541","doi":"https://doi.org/10.1155/2018/1601738","title":"Salvaging Digital Replantation and Revascularisation: Efficiency of Heparin Solution Subcutaneous Injection","display_name":"Salvaging Digital Replantation and Revascularisation: Efficiency of Heparin Solution Subcutaneous Injection","publication_year":2018,"publication_date":"2018-11-21","ids":{"openalex":"https://openalex.org/W2901257541","doi":"https://doi.org/10.1155/2018/1601738","mag":"2901257541","pmid":"https://pubmed.ncbi.nlm.nih.gov/30584577","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6280226"},"language":"en","primary_location":{"id":"doi:10.1155/2018/1601738","doi":"https://doi.org/10.1155/2018/1601738","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2018/1601738","pdf_url":"https://downloads.hindawi.com/journals/srp/2018/1601738.pdf","source":{"id":"https://openalex.org/S4210212864","display_name":"Surgery Research and Practice","issn_l":"2356-6124","issn":["2356-6124","2356-7759"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery Research and Practice","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/srp/2018/1601738.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040877212","display_name":"Hazem Alfeky","orcid":"https://orcid.org/0000-0002-0226-3408","observed_orcids":["https://orcid.org/0000-0002-0226-3408"]},"institutions":[{"id":"https://openalex.org/I2801674322","display_name":"University Hospital Coventry","ror":"https://ror.org/025821s54","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801674322","https://openalex.org/I2802705189"]},{"id":"https://openalex.org/I2802705189","display_name":"University Hospitals Coventry and Warwickshire NHS Trust","ror":"https://ror.org/025n38288","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802705189"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Haz Alfeky","raw_affiliation_strings":["Consultant Plastic Surgeon, Plastic Surgery Department, University Hospital Coventry and Warwickshire, Coventry, UK"],"raw_orcid":"https://orcid.org/0000-0002-0226-3408","affiliations":[{"raw_affiliation_string":"Consultant Plastic Surgeon, Plastic Surgery Department, University Hospital Coventry and Warwickshire, Coventry, UK","institution_ids":["https://openalex.org/I2801674322","https://openalex.org/I2802705189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113854419","display_name":"Paul McArthur","orcid":"https://orcid.org/0000-0002-2719-1287","observed_orcids":["https://orcid.org/0000-0002-2719-1287"]},"institutions":[{"id":"https://openalex.org/I4210142829","display_name":"Whiston Hospital","ror":"https://ror.org/053vvhn22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800695023","https://openalex.org/I4210142829"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul McArthur","raw_affiliation_strings":["Consultant Plastic Surgery, Whiston Hospital, Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Consultant Plastic Surgery, Whiston Hospital, Liverpool, UK","institution_ids":["https://openalex.org/I4210142829"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108139403","display_name":"Yasser Helmy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184834183","display_name":"Al-Azhar University","ror":"https://ror.org/05fnp1145","country_code":"EG","type":"education","lineage":["https://openalex.org/I184834183"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Yasser Helmy","raw_affiliation_strings":["Professor of Plastic Surgery, Alazhar University Hospitals, Cairo, Egypt"],"raw_orcid":"https://orcid.org/0000-0001-9238-1450","affiliations":[{"raw_affiliation_string":"Professor of Plastic Surgery, Alazhar University Hospitals, Cairo, Egypt","institution_ids":["https://openalex.org/I184834183"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5040877212"],"corresponding_institution_ids":["https://openalex.org/I2801674322","https://openalex.org/I2802705189"],"apc_list":{"value":820,"currency":"USD","value_usd":820},"apc_paid":{"value":820,"currency":"USD","value_usd":820},"fwci":1.0319,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.76948929,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"2018","issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10599","display_name":"Reconstructive Surgery and Microvascular Techniques","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10599","display_name":"Reconstructive Surgery and Microvascular Techniques","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10630","display_name":"Orthopedic Surgery and Rehabilitation","score":0.01489999983459711,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11554","display_name":"Vascular Procedures and Complications","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/digit-replantation","display_name":"digital replantation","score":0.9129999876022339},{"id":"https://openalex.org/keywords/venous-congestion","display_name":"venous congestion","score":0.9399999976158142},{"id":"https://openalex.org/keywords/venous-anastomosis","display_name":"venous anastomosis","score":0.7009999752044678},{"id":"https://openalex.org/keywords/microsurgery","display_name":"microsurgery","score":0.6230000257492065},{"id":"https://openalex.org/keywords/anticoagulation-safety","display_name":"anticoagulant safety","score":0.6389999985694885},{"id":"https://openalex.org/keywords/thromboprophylaxis","display_name":"thromboprophylaxis","score":0.6169999837875366}],"concepts":[{"id":"https://openalex.org/C2779345524","wikidata":"https://www.wikidata.org/wiki/Q7314029","display_name":"Replantation","level":2,"score":0.8789660930633545},{"id":"https://openalex.org/C2777557582","wikidata":"https://www.wikidata.org/wiki/Q190016","display_name":"Heparin","level":2,"score":0.7443134784698486},{"id":"https://openalex.org/C2776390293","wikidata":"https://www.wikidata.org/wiki/Q2035485","display_name":"Subcutaneous injection","level":2,"score":0.5245145559310913},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.401538610458374},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.35763612389564514},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.29956746101379395},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16362756490707397}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1155/2018/1601738","doi":"https://doi.org/10.1155/2018/1601738","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2018/1601738","pdf_url":"https://downloads.hindawi.com/journals/srp/2018/1601738.pdf","source":{"id":"https://openalex.org/S4210212864","display_name":"Surgery Research and Practice","issn_l":"2356-6124","issn":["2356-6124","2356-7759"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery Research and Practice","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5273563","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6280226","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6280226","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6280226","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surg Res Pract","raw_type":"Text"},{"id":"pmid:30584577","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30584577","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery research and practice","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:3cc7b54d482a4ffdb36b4b07a4e3a9f3","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/3cc7b54d482a4ffdb36b4b07a4e3a9f3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Surgery Research and Practice, Vol 2018 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1155/2018/1601738","doi":"https://doi.org/10.1155/2018/1601738","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2018/1601738","pdf_url":"https://downloads.hindawi.com/journals/srp/2018/1601738.pdf","source":{"id":"https://openalex.org/S4210212864","display_name":"Surgery Research and Practice","issn_l":"2356-6124","issn":["2356-6124","2356-7759"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery Research and Practice","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9789000153541565}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320331636","display_name":"University Hospitals Coventry and Warwickshire NHS Trust","ror":"https://ror.org/025n38288"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2901257541.pdf","grobid_xml":"https://content.openalex.org/works/W2901257541.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W126005280","https://openalex.org/W142623305","https://openalex.org/W197270906","https://openalex.org/W1965030572","https://openalex.org/W1966665059","https://openalex.org/W1970284876","https://openalex.org/W1976617224","https://openalex.org/W1976918413","https://openalex.org/W1985624390","https://openalex.org/W2000336095","https://openalex.org/W2001643101","https://openalex.org/W2001709439","https://openalex.org/W2021196901","https://openalex.org/W2023650960","https://openalex.org/W2028234039","https://openalex.org/W2030330395","https://openalex.org/W2043892178","https://openalex.org/W2048835873","https://openalex.org/W2058613683","https://openalex.org/W2060440504","https://openalex.org/W2073590810","https://openalex.org/W2082058887","https://openalex.org/W2094630333","https://openalex.org/W2156332586","https://openalex.org/W2162356386","https://openalex.org/W2167515852","https://openalex.org/W2186628204","https://openalex.org/W2325022685","https://openalex.org/W2413998047","https://openalex.org/W4205312708"],"related_works":["https://openalex.org/W1965030572","https://openalex.org/W2094630333","https://openalex.org/W2167515852","https://openalex.org/W2283350096","https://openalex.org/W2112326960","https://openalex.org/W4306682590","https://openalex.org/W2385522925","https://openalex.org/W2999169475","https://openalex.org/W2460033262","https://openalex.org/W2346134888"],"abstract_inverted_index":{"BACKGROUND:":[0],"Distal":[1],"digital":[2],"replantation":[3,29,202],"and":[4,51,153,207,238],"revascularisation":[5],"remains":[6],"one":[7],"of":[8,17,34,68,81,84,94,111,148,178],"the":[9,15,23,32,112,118,133,149,163,191,222,235],"demanding":[10],"microsurgical":[11],"procedures":[12],"due":[13,30],"to":[14,31,47,233],"difficulty":[16,33],"vascular":[18],"anastomosis.":[19],"Venous":[20],"congestion":[21,74,129,196],"is":[22,44,197,205,229],"most":[24],"commonly":[25,45],"encountered":[26],"problem":[27],"after":[28],"venous":[35,49,73,128,195],"anastomosis":[36],"in":[37,60,75,91,210,224],"traumatic":[38],"injuries.":[39],"Heparin,":[40],"among":[41],"other":[42],"drugs,":[43],"used":[46],"facilitate":[48],"drainage":[50],"prevent":[52],"thrombosis.":[53],"However,":[54,218],"systemic":[55,139,213],"heparin":[56,70,86,187,214],"can":[57,189],"be":[58,216],"contraindicated":[59],"some":[61],"patients.":[62,77],"The":[63,151],"senior":[64],"author":[65],"has":[66,101],"experience":[67],"subcutaneous":[69],"injection":[71],"for":[72,201],"thirteen":[76,226],"METHODS:":[78],"An":[79],"amount":[80],"1":[82],"ml":[83,93],"calcium":[85],"(25,000":[87],"U)":[88],"was":[89,114,123],"mixed":[90],"2.4":[92],"normal":[95,164],"saline":[96],"making":[97],"a":[98,198,230],"solution":[99,113],"that":[100],"1000":[102,107],"U":[103,108],"per":[104],"0.1":[105],"ml.":[106],"(0.1":[109],"ml)":[110],"injected":[115],"directly":[116],"into":[117],"congested":[119,134],"replanted":[120,135,192],"digits.":[121],"This":[122],"repeated":[124],"twice":[125],"daily":[126],"until":[127],"improved.":[130],"RESULTS:":[131],"All":[132],"digits":[136,193],"survived":[137],"without":[138],"side":[140,146,239],"effects.":[141,240],"There":[142],"were":[143,174],"no":[144,172],"local":[145],"effects":[147],"treatment.":[150],"PT":[152],"APTT":[154],"have":[155,168],"shown":[156],"slight":[157],"increase":[158],"but":[159,171],"they":[160],"remained":[161],"within":[162],"range.":[165],"Haemoglobin":[166],"levels":[167],"dropped":[169],"slightly":[170],"patients":[173,211,227],"at":[175],"any":[176],"risk":[177],"developing":[179],"anaemia":[180],"or":[181],"needed":[182],"blood":[183],"transfusion.":[184],"CONCLUSIONS:":[185],"Subcutaneous":[186],"injections":[188],"salvage":[190],"when":[194],"warning":[199],"flag":[200],"failure.":[203],"It":[204],"safe":[206],"very":[208],"efficient":[209],"where":[212],"cannot":[215],"administered.":[217],"this":[219],"article":[220],"shows":[221],"results":[223],"only":[225],"which":[228],"small":[231],"number":[232],"show":[234],"efficacy,":[236],"safety,":[237]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":4}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2018-11-29T00:00:00"}