{"id":"https://openalex.org/W2901161970","doi":"https://doi.org/10.1155/2018/7437858","title":"Oral Fludrocortisone Test for Salt\u2010Sensitive Screening in Hypertensive Patients: A Randomized Crossover Trial","display_name":"Oral Fludrocortisone Test for Salt\u2010Sensitive Screening in Hypertensive Patients: A Randomized Crossover Trial","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2901161970","doi":"https://doi.org/10.1155/2018/7437858","mag":"2901161970","pmid":"https://pubmed.ncbi.nlm.nih.gov/30581606","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6276467"},"language":"en","primary_location":{"id":"doi:10.1155/2018/7437858","doi":"https://doi.org/10.1155/2018/7437858","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2018/7437858","pdf_url":"https://downloads.hindawi.com/journals/ijhy/2018/7437858.pdf","source":{"id":"https://openalex.org/S52659601","display_name":"International Journal of Hypertension","issn_l":"2090-0384","issn":["2090-0384","2090-0392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Hypertension","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://downloads.hindawi.com/journals/ijhy/2018/7437858.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056961131","display_name":"Andrea Pio-Abreu","orcid":"https://orcid.org/0000-0002-5118-7990","observed_orcids":["https://orcid.org/0000-0002-5118-7990"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210142721","display_name":"Hospital Universit\u00e1rio da Universidade de S\u00e3o Paulo","ror":"https://ror.org/0406jsq08","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I17974374","https://openalex.org/I4210142721"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Andrea Pio-Abreu","raw_affiliation_strings":["Hypertension Unit, Renal Division of Hospital das Cl\u00ednicas, University of S\u00e3o Paulo Medical School, S\u00e3o Paulo, SP, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-5118-7990","affiliations":[{"raw_affiliation_string":"Hypertension Unit, Renal Division of Hospital das Cl\u00ednicas, University of S\u00e3o Paulo Medical School, S\u00e3o Paulo, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210142721","https://openalex.org/I4210145268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045353820","display_name":"Isac de Castro","orcid":"https://orcid.org/0000-0002-1160-3064","observed_orcids":["https://orcid.org/0000-0002-1160-3064","https://orcid.org/0000-0003-3044-0704"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Isac de Castro","raw_affiliation_strings":["Renal Division of Hospital das Cl\u00ednicas, University of S\u00e3o Paulo Medical School, S\u00e3o Paulo, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Renal Division of Hospital das Cl\u00ednicas, University of S\u00e3o Paulo Medical School, S\u00e3o Paulo, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210145268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053214020","display_name":"Giov\u00e4nio Vieira da Silva","orcid":"https://orcid.org/0000-0003-3370-9326","observed_orcids":["https://orcid.org/0000-0003-3370-9326"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210142721","display_name":"Hospital Universit\u00e1rio da Universidade de S\u00e3o Paulo","ror":"https://ror.org/0406jsq08","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I17974374","https://openalex.org/I4210142721"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Giovanio Vieira da Silva","raw_affiliation_strings":["Hypertension Unit, Renal Division of Hospital das Cl\u00ednicas, University of S\u00e3o Paulo Medical School, S\u00e3o Paulo, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hypertension Unit, Renal Division of Hospital das Cl\u00ednicas, University of S\u00e3o Paulo Medical School, S\u00e3o Paulo, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210142721","https://openalex.org/I4210145268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109245367","display_name":"K\u00e1tia Coelho Ortega","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210142721","display_name":"Hospital Universit\u00e1rio da Universidade de S\u00e3o Paulo","ror":"https://ror.org/0406jsq08","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I17974374","https://openalex.org/I4210142721"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Katia Coelho Ortega","raw_affiliation_strings":["Hypertension Unit, Renal Division of Hospital das Cl\u00ednicas, University of S\u00e3o Paulo Medical School, S\u00e3o Paulo, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hypertension Unit, Renal Division of Hospital das Cl\u00ednicas, University of S\u00e3o Paulo Medical School, S\u00e3o Paulo, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210142721","https://openalex.org/I4210145268"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078259781","display_name":"D\u00e9cio Mion","orcid":"https://orcid.org/0000-0002-1564-121X","observed_orcids":["https://orcid.org/0000-0002-1564-121X"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210142721","display_name":"Hospital Universit\u00e1rio da Universidade de S\u00e3o Paulo","ror":"https://ror.org/0406jsq08","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I17974374","https://openalex.org/I4210142721"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Decio Mion","raw_affiliation_strings":["Hypertension Unit, Renal Division of Hospital das Cl\u00ednicas, University of S\u00e3o Paulo Medical School, S\u00e3o Paulo, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hypertension Unit, Renal Division of Hospital das Cl\u00ednicas, University of S\u00e3o Paulo Medical School, S\u00e3o Paulo, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210142721","https://openalex.org/I4210145268"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5056961131"],"corresponding_institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210142721","https://openalex.org/I4210145268"],"apc_list":{"value":1790,"currency":"USD","value_usd":1790},"apc_paid":{"value":1790,"currency":"USD","value_usd":1790},"fwci":0.0,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"2018","issue":"1","first_page":"7437858","last_page":"7437858"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12075","display_name":"Sodium Intake and Health","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12075","display_name":"Sodium Intake and Health","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.02459999918937683,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/salt-sensitivity","display_name":"salt sensitivity","score":0.9110000133514404},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.8849999904632568},{"id":"https://openalex.org/keywords/sodium-intake","display_name":"sodium intake","score":0.5759999752044678},{"id":"https://openalex.org/keywords/blood-pressure-response","display_name":"blood pressure response","score":0.6729999780654907},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.6269999742507935},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.8460000157356262}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9156675338745117},{"id":"https://openalex.org/C2776899810","wikidata":"https://www.wikidata.org/wiki/Q2697578","display_name":"Fludrocortisone","level":3,"score":0.8468911647796631},{"id":"https://openalex.org/C87813604","wikidata":"https://www.wikidata.org/wiki/Q1242899","display_name":"Crossover study","level":4,"score":0.7907512187957764},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.7104085683822632},{"id":"https://openalex.org/C122507166","wikidata":"https://www.wikidata.org/wiki/Q628906","display_name":"Crossover","level":2,"score":0.4890654981136322},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30376994609832764},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.1130082905292511},{"id":"https://openalex.org/C2778709874","wikidata":"https://www.wikidata.org/wiki/Q190875","display_name":"Hydrocortisone","level":2,"score":0.07659810781478882},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.052667438983917236},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.0},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1155/2018/7437858","doi":"https://doi.org/10.1155/2018/7437858","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2018/7437858","pdf_url":"https://downloads.hindawi.com/journals/ijhy/2018/7437858.pdf","source":{"id":"https://openalex.org/S52659601","display_name":"International Journal of Hypertension","issn_l":"2090-0384","issn":["2090-0384","2090-0392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Hypertension","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5273350","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6276467","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:30581606","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30581606","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of hypertension","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6276467","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6276467/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Hypertens","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:c6816708324d4d33bdd84229b87da408","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c6816708324d4d33bdd84229b87da408","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Hypertension, Vol 2018 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1155/2018/7437858","doi":"https://doi.org/10.1155/2018/7437858","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2018/7437858","pdf_url":"https://downloads.hindawi.com/journals/ijhy/2018/7437858.pdf","source":{"id":"https://openalex.org/S52659601","display_name":"International Journal of Hypertension","issn_l":"2090-0384","issn":["2090-0384","2090-0392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Hypertension","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[{"id":"https://openalex.org/G6355118437","display_name":"Fludrocortisone's test in the identification of salt sensitivity","funder_award_id":"10/17072-6","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G8102092985","display_name":null,"funder_award_id":"2010/17072-6","funder_id":"https://openalex.org/F4320322025","funder_display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico"}],"funders":[{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2901161970.pdf","grobid_xml":"https://content.openalex.org/works/W2901161970.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W20421448","https://openalex.org/W1494052777","https://openalex.org/W1974208490","https://openalex.org/W1985258136","https://openalex.org/W1985667045","https://openalex.org/W1993252396","https://openalex.org/W2006884514","https://openalex.org/W2023281555","https://openalex.org/W2026194061","https://openalex.org/W2037514270","https://openalex.org/W2038421266","https://openalex.org/W2052202150","https://openalex.org/W2059361773","https://openalex.org/W2092438884","https://openalex.org/W2114897999","https://openalex.org/W2148076762","https://openalex.org/W2159456641","https://openalex.org/W2161136893","https://openalex.org/W2167883207","https://openalex.org/W2314707437","https://openalex.org/W2327674570","https://openalex.org/W2410572069","https://openalex.org/W2502302520","https://openalex.org/W2512804711","https://openalex.org/W2598538875","https://openalex.org/W2729521907","https://openalex.org/W2775075663","https://openalex.org/W4248519369","https://openalex.org/W4300429268"],"related_works":["https://openalex.org/W6949701045","https://openalex.org/W4287551531","https://openalex.org/W4287672624","https://openalex.org/W7120685991","https://openalex.org/W2049631634","https://openalex.org/W2327674570","https://openalex.org/W2319871363","https://openalex.org/W1966824543","https://openalex.org/W7221634672","https://openalex.org/W2115930085"],"abstract_inverted_index":{"BACKGROUND:":[0],"Salt":[1],"sensitivity":[2,116,134,142,157],"is":[3,40,150,188],"associated":[4],"with":[5,55,93,140,190],"an":[6,170],"increased":[7],"cardiovascular":[8],"risk,":[9],"but":[10],"the":[11,28,60,94,104,108,111,162,174,180],"gold":[12],"standard":[13],"method":[14],"(diet":[15],"cycles)":[16],"requires":[17],"24-h":[18],"urine":[19],"samples":[20],"and":[21,69,83,143],"has":[22],"poor":[23],"patient":[24],"compliance.":[25],"OBJECTIVES:":[26],"Test":[27],"hypothesis":[29],"that":[30,98],"oral":[31],"fludrocortisone":[32,112,130,148],"(0.4":[33],"mg":[34],"per":[35],"day":[36],"for":[37,154],"7":[38],"days)":[39],"a":[41,51,89,118,151],"good":[42,127,152],"alternative":[43],"in":[44,88,131,158,179],"identifying":[45],"salt-sensitive":[46,101],"patients.":[47,160],"METHODOLOGY:":[48],"We":[49],"conducted":[50],"randomized":[52],"crossover":[53],"study":[54],"30":[56],"hypertensive":[57,159],"individuals":[58],"comprising":[59],"following":[61],"steps:":[62],"(1)":[63],"washout;":[64],"(2)":[65],"phase":[66,77],"A":[67,82,126],"(low-":[68],"high-sodium":[70],"diet":[71,176],"cycles);":[72],"(3)":[73],"washout":[74],"2;":[75],"(4)":[76],"B":[78,84],"(fludrocortisone":[79],"test).":[80],"Phase":[81],"steps":[85],"were":[86,100],"performed":[87],"random":[90],"way.":[91],"Consistent":[92],"literature,":[95],"we":[96],"found":[97],"53.3%":[99],"according":[102],"to":[103,173],"reference":[105],"test.":[106],"Using":[107],"ROC":[109],"curve,":[110],"test":[113,149,167],"defined":[114],"salt":[115,133,156,183],"by":[117],"median":[119],"blood":[120],"pressure":[121],"increase":[122],"of":[123,129,182],"\u22653":[124],"mmHg.":[125],"accuracy":[128],"detecting":[132],"was":[135],"observed":[136],"(AUC:":[137],"0.732\u00b10.065;":[138],"p<0.001),":[139],"80%":[141],"53%":[144],"specificity.":[145],"CONCLUSION:":[146],"The":[147],"option":[153],"screening":[155],"However,":[161],"low":[163],"specificity":[164],"prevents":[165],"this":[166],"from":[168],"being":[169],"ideal":[171],"substitute":[172],"labor-intensive":[175],"cycles":[177],"exam":[178],"definition":[181],"sensitivity.":[184],"This":[185],"clinical":[186],"trial":[187],"registered":[189],"NCT01453959.":[191]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-11-29T00:00:00"}