{"id":"https://openalex.org/W2899208209","doi":"https://doi.org/10.26442/2079-5831_17.2.55-59","title":"Effectiveness of micronized progesterone for the prevention of miscarriage","display_name":"Effectiveness of micronized progesterone for the prevention of miscarriage","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2899208209","doi":"https://doi.org/10.26442/2079-5831_17.2.55-59","mag":"2899208209"},"language":"en","primary_location":{"id":"doi:10.26442/2079-5831_17.2.55-59","doi":"https://doi.org/10.26442/2079-5831_17.2.55-59","is_oa":true,"landing_page_url":"http://doi.org/10.26442/2079-5831_17.2.55-59","pdf_url":null,"source":{"id":"https://openalex.org/S4210178529","display_name":"GYNECOLOGY","issn_l":"2079-5696","issn":["2079-5696","2079-5831"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310312781","host_organization_name":"IP Berlin A.V.","host_organization_lineage":["https://openalex.org/P4310312781"],"host_organization_lineage_names":["IP Berlin A.V."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gynecology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2899208209"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://doi.org/10.26442/2079-5831_17.2.55-59","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038603395","display_name":"L. I. Maltseva","orcid":"https://orcid.org/0000-0003-0999-4374","observed_orcids":["https://orcid.org/0000-0003-0999-4374"]},"institutions":[{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]},{"id":"https://openalex.org/I4210127959","display_name":"Kazan State Medical Academy","ror":"https://ror.org/02ct1m089","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210127959"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"L.I. Maltseva","raw_affiliation_strings":["Kazan State Medical Academy of the Ministry of Health of the Russian Federation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kazan State Medical Academy of the Ministry of Health of the Russian Federation","institution_ids":["https://openalex.org/I4210117042","https://openalex.org/I4210127959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077018867","display_name":"D M Nikogosyan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D.M. Nikogosyan","raw_affiliation_strings":["Republican Clinical Hospital \u21162. 420043, Russian Federation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Republican Clinical Hospital \u21162. 420043, Russian Federation","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":300,"currency":"EUR","value_usd":323},"apc_paid":{"value":300,"currency":"EUR","value_usd":323},"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"17","issue":"2","first_page":"55","last_page":"59"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11290","display_name":"Preterm Birth and Chorioamnionitis","score":0.013000000268220901,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.011599999852478504,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/micronized-progesterone","display_name":"micronized progesterone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/miscarriage-prevention","display_name":"miscarriage prevention","score":0.9869999885559082},{"id":"https://openalex.org/keywords/early-pregnancy","display_name":"early pregnancy","score":0.6899999976158142},{"id":"https://openalex.org/keywords/progesterone-deficiency","display_name":"progesterone deficiency","score":0.7300000190734863},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.7749999761581421},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.8399999737739563},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.9480000138282776},{"id":"https://openalex.org/keywords/thrombophilia","display_name":"thrombophilia","score":0.8669999837875366},{"id":"https://openalex.org/keywords/congenital-uterine-anomalies","display_name":"congenital uterine anomalies","score":0.8019999861717224},{"id":"https://openalex.org/keywords/retrochorial-hematoma","display_name":"retrochorial hematoma","score":0.8220000267028809},{"id":"https://openalex.org/keywords/hemostasis","display_name":"hemostasis","score":0.8769999742507935},{"id":"https://openalex.org/keywords/d-dimer","display_name":"D-dimer","score":0.7059999704360962},{"id":"https://openalex.org/keywords/platelet-aggregation","display_name":"platelet aggregation","score":0.6019999980926514}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8442238569259644},{"id":"https://openalex.org/C2779245376","wikidata":"https://www.wikidata.org/wiki/Q28693","display_name":"Miscarriage","level":3,"score":0.7711431980133057},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6622823476791382},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.5621210932731628},{"id":"https://openalex.org/C2778589496","wikidata":"https://www.wikidata.org/wiki/Q487937","display_name":"Hemostasis","level":2,"score":0.5055356025695801},{"id":"https://openalex.org/C145333580","wikidata":"https://www.wikidata.org/wiki/Q260946","display_name":"Anamnesis","level":2,"score":0.478076696395874},{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.4682553708553314},{"id":"https://openalex.org/C2778642596","wikidata":"https://www.wikidata.org/wiki/Q8452","display_name":"Abortion","level":3,"score":0.46223312616348267},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.41605156660079956},{"id":"https://openalex.org/C2777688143","wikidata":"https://www.wikidata.org/wiki/Q179399","display_name":"Infertility","level":3,"score":0.4121550917625427},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2505108118057251},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.26442/2079-5831_17.2.55-59","doi":"https://doi.org/10.26442/2079-5831_17.2.55-59","is_oa":true,"landing_page_url":"http://doi.org/10.26442/2079-5831_17.2.55-59","pdf_url":null,"source":{"id":"https://openalex.org/S4210178529","display_name":"GYNECOLOGY","issn_l":"2079-5696","issn":["2079-5696","2079-5831"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310312781","host_organization_name":"IP Berlin A.V.","host_organization_lineage":["https://openalex.org/P4310312781"],"host_organization_lineage_names":["IP Berlin A.V."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gynecology","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:84617b035e4f4a62831dc00d756cd22d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/84617b035e4f4a62831dc00d756cd22d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u0413\u0438\u043d\u0435\u043a\u043e\u043b\u043e\u0433\u0438\u044f, Vol 17, Iss 2, Pp 56-59 (2015)","raw_type":"article"},{"id":"mag:3007513456","doi":null,"is_oa":true,"landing_page_url":"https://gynecology.orscience.ru/2079-5831/article/view/28438/pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4210178529","display_name":"GYNECOLOGY","issn_l":"2079-5696","issn":["2079-5696","2079-5831"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310312781","host_organization_name":"IP Berlin A.V.","host_organization_lineage":["https://openalex.org/P4310312781"],"host_organization_lineage_names":["IP Berlin A.V."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"GYNECOLOGY","raw_type":null}],"best_oa_location":{"id":"doi:10.26442/2079-5831_17.2.55-59","doi":"https://doi.org/10.26442/2079-5831_17.2.55-59","is_oa":true,"landing_page_url":"http://doi.org/10.26442/2079-5831_17.2.55-59","pdf_url":null,"source":{"id":"https://openalex.org/S4210178529","display_name":"GYNECOLOGY","issn_l":"2079-5696","issn":["2079-5696","2079-5831"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310312781","host_organization_name":"IP Berlin A.V.","host_organization_lineage":["https://openalex.org/P4310312781"],"host_organization_lineage_names":["IP Berlin A.V."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gynecology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2331858014","https://openalex.org/W2802511981","https://openalex.org/W4210833772","https://openalex.org/W7123339009","https://openalex.org/W4385945618","https://openalex.org/W3003912962","https://openalex.org/W2997503921","https://openalex.org/W3116455906","https://openalex.org/W2036895667"],"abstract_inverted_index":{"The":[0,25,164,243],"data":[1],"on":[2],"the":[3,10,40,54,57,89,93,96,107,124,131,139,144,152,157,171,181,183,203],"efficacy":[4],"of":[5,12,36,38,43,56,59,79,95,98,111,133,138,149,166,173,177,185,205,228,234,245,267],"micronized":[6,120,246],"progesterone":[7,150,174,224,247],"(Prajisun)":[8],"for":[9],"prevention":[11],"miscarriage":[13],"in":[14,47,123,130,143,151,180,220,240,249,252,263],"women":[15,29,75,253],"with":[16,119,156,170,207,254],"a":[17,77,217],"obstetric":[18,255],"and":[19,23,104,116,135,175,231,256,261],"gynecological":[20,257],"history.":[21],"Materials":[22],"methods.":[24],"study":[26],"involved":[27],"56":[28],"aged":[30],"19-38":[31],"years":[32],"at":[33],"4-14":[34],"weeks":[35,214],"pregnancy,":[37],"which":[39,186],"main":[41,145],"group":[42,71,146],"30":[44],"were:":[45],"infertility":[46],"anamnesis":[48],"-":[49,62,66,196,199],"17":[50],"thrombophilic":[51],"states":[52],"against":[53],"background":[55,204],"centers":[58],"urogenital":[60],"infection":[61],"7,":[63],"uterine":[64],"malformations":[65],"6":[67],"pregnant.":[68],"A":[69],"control":[70],"comprised":[72],"26":[73],"healthy":[74],"without":[76],"history":[78,258],"complications":[80],"during":[81],"current":[82],"pregnancy.":[83],"All":[84],"patients":[85],"have":[86],"gone":[87],"through":[88],"physical":[90],"examination,":[91],"including":[92],"definition":[94],"parameters":[97],"hemostasis":[99],"D-dimer,":[100],"AIII,":[101],"protein":[102],"C":[103],"S.":[105],"In":[106],"study,":[108],"blood":[109,153],"levels":[110,148,227],"progesterone,":[112],"interleukin-1b,":[113],"interferon-y":[114,198],"before":[115],"after":[117],"treatment":[118,206],"progesterone.":[121],"Changes":[122],"hemostatic":[125],"system":[126],"is":[127],"also":[128],"evaluated":[129],"dynamics":[132],"observation":[134],"treatment.The":[136],"results":[137],"study.":[140],"Among":[141],"women,":[142],"lower":[147],"were":[154],"found,":[155],"most":[158],"pronounced":[159],"case":[160],"being":[161],"retrochorial":[162],"hematoma.":[163],"threat":[165],"abortion":[167],"directly":[168],"correlated":[169],"level":[172],"content":[176],"proinflammatory":[178],"cytokines":[179],"blood,":[182],"values":[184],"are":[187],"several":[188],"times":[189],"higher":[190],"than":[191],"health":[192],"indicators:":[193],",":[194],"interleukin-1b":[195],"5,":[197],"3,7":[200],"times.":[201],"Against":[202],"400":[208],"mg":[209],"Prajisun":[210,248],"vaginally":[211],"within":[212],"two":[213],"there":[215],"was":[216],"significant":[218],"decline":[219],"pro-inflammatory":[221],"cytokines,":[222],"increased":[223],"levels,":[225],"normal":[226],"fibrinogen,":[229],"D-dimer":[230],"spontaneous":[232],"rate":[233],"platelet":[235],"aggregation.":[236],"Pregnancy":[237],"progressed":[238],"successfully":[239],"all":[241],"women.Conclusion.":[242],"use":[244],"early":[250],"pregnancy":[251],"pathogenetically":[259],"substantiated":[260],"effective":[262],"reducing":[264],"high":[265],"risk":[266],"miscarriage.":[268]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2018-11-09T00:00:00"}