{"id":"https://openalex.org/W2898948408","doi":"https://doi.org/10.1080/17460441.2018.1542427","title":"Developments with 3D bioprinting for novel drug discovery","display_name":"Developments with 3D bioprinting for novel drug discovery","publication_year":2018,"publication_date":"2018-11-01","ids":{"openalex":"https://openalex.org/W2898948408","doi":"https://doi.org/10.1080/17460441.2018.1542427","mag":"2898948408","pmid":"https://pubmed.ncbi.nlm.nih.gov/30384781","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6494715"},"language":"en","primary_location":{"id":"doi:10.1080/17460441.2018.1542427","doi":"https://doi.org/10.1080/17460441.2018.1542427","is_oa":false,"landing_page_url":"https://doi.org/10.1080/17460441.2018.1542427","pdf_url":null,"source":{"id":"https://openalex.org/S142541038","display_name":"Expert Opinion on Drug Discovery","issn_l":"1746-0441","issn":["1746-0441","1746-045X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Opinion on Drug Discovery","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6494715","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002857101","display_name":"Aishwarya Satpathy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98365261","display_name":"Indian Institute of Engineering Science and Technology, Shibpur","ror":"https://ror.org/02ytfzr55","country_code":"IN","type":"education","lineage":["https://openalex.org/I98365261"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Aishwarya Satpathy","raw_affiliation_strings":["Centre for Healthcare Science and Technology, Indian Institute of Engineering Science and Technology Shibpur, Howrah, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Healthcare Science and Technology, Indian Institute of Engineering Science and Technology Shibpur, Howrah, India","institution_ids":["https://openalex.org/I98365261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046111170","display_name":"Pallab Datta","orcid":"https://orcid.org/0000-0002-7404-4917","observed_orcids":["https://orcid.org/0000-0002-7404-4917"]},"institutions":[{"id":"https://openalex.org/I98365261","display_name":"Indian Institute of Engineering Science and Technology, Shibpur","ror":"https://ror.org/02ytfzr55","country_code":"IN","type":"education","lineage":["https://openalex.org/I98365261"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pallab Datta","raw_affiliation_strings":["Centre for Healthcare Science and Technology, Indian Institute of Engineering Science and Technology Shibpur, Howrah, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Healthcare Science and Technology, Indian Institute of Engineering Science and Technology Shibpur, Howrah, India","institution_ids":["https://openalex.org/I98365261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101584117","display_name":"Yang Bo Wu","orcid":"https://orcid.org/0000-0003-4152-679X","observed_orcids":["https://orcid.org/0000-0003-4152-679X"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yang Wu","raw_affiliation_strings":["Engineering Science and Mechanics Department, Penn State University, University Park, PA, USA","The Huck Institutes of the Life Sciences, Penn State University, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engineering Science and Mechanics Department, Penn State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"The Huck Institutes of the Life Sciences, Penn State University, USA","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013824445","display_name":"Bugra Ayan","orcid":"https://orcid.org/0000-0003-4614-263X","observed_orcids":["https://orcid.org/0000-0003-4614-263X"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bugra Ayan","raw_affiliation_strings":["Engineering Science and Mechanics Department, Penn State University, University Park, PA, USA","The Huck Institutes of the Life Sciences, Penn State University, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engineering Science and Mechanics Department, Penn State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"The Huck Institutes of the Life Sciences, Penn State University, USA","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065992872","display_name":"Ertu\u011frul Bayram","orcid":"https://orcid.org/0000-0001-8713-7613","observed_orcids":["https://orcid.org/0000-0001-8713-7613"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ertugrul Bayram","raw_affiliation_strings":["Medical Oncology Department, Agri State Hospital, Agri, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology Department, Agri State Hospital, Agri, Turkey","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083046197","display_name":"Ibrahim Tarik Ozbolat","orcid":"https://orcid.org/0000-0001-8328-4528","observed_orcids":["https://orcid.org/0000-0001-8328-4528"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ibrahim T. Ozbolat","raw_affiliation_strings":["Biomedical Engineering Department, Penn State University, University Park, PA, USA","Engineering Science and Mechanics Department, Penn State University, University Park, PA, USA","Materials Research Institute, Penn State University, USA","The Huck Institutes of the Life Sciences, Penn State University, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, Penn State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Engineering Science and Mechanics Department, Penn State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Materials Research Institute, Penn State University, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"The Huck Institutes of the Life Sciences, Penn State University, USA","institution_ids":["https://openalex.org/I130769515"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5083046197"],"corresponding_institution_ids":["https://openalex.org/I130769515"],"apc_list":null,"apc_paid":null,"fwci":0.4053,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.40206948,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"13","issue":"12","first_page":"1115","last_page":"1129"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/3d-bioprinting","display_name":"3D bioprinting","score":1.0},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"drug discovery","score":0.9449999928474426},{"id":"https://openalex.org/keywords/3d-cell-culture","display_name":"3D cell culture","score":0.8059999942779541},{"id":"https://openalex.org/keywords/tissue-microenvironment","display_name":"tissue microenvironment","score":0.7850000262260437}],"concepts":[{"id":"https://openalex.org/C2780625559","wikidata":"https://www.wikidata.org/wiki/Q5152592","display_name":"Commercialization","level":2,"score":0.705349326133728},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.6600944995880127},{"id":"https://openalex.org/C2779718196","wikidata":"https://www.wikidata.org/wiki/Q17018741","display_name":"3D bioprinting","level":3,"score":0.6191479563713074},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5805234313011169},{"id":"https://openalex.org/C188087704","wikidata":"https://www.wikidata.org/wiki/Q369577","display_name":"Standardization","level":2,"score":0.5484474897384644},{"id":"https://openalex.org/C120060458","wikidata":"https://www.wikidata.org/wiki/Q10145","display_name":"Milestone","level":2,"score":0.5386244058609009},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.5119608640670776},{"id":"https://openalex.org/C3020580240","wikidata":"https://www.wikidata.org/wiki/Q663272","display_name":"Expert opinion","level":2,"score":0.49686744809150696},{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.49408939480781555},{"id":"https://openalex.org/C2779652045","wikidata":"https://www.wikidata.org/wiki/Q507443","display_name":"Pharmaceutical industry","level":2,"score":0.47690272331237793},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.46273598074913025},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.4464435577392578},{"id":"https://openalex.org/C206345919","wikidata":"https://www.wikidata.org/wiki/Q20380951","display_name":"Resource (disambiguation)","level":2,"score":0.4438122808933258},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.3970944881439209},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.21666443347930908},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2088947892189026},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.20720171928405762},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.20514950156211853},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.17556652426719666},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14025089144706726},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.13554218411445618},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.08327522873878479},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.0},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.0},{"id":"https://openalex.org/C162853370","wikidata":"https://www.wikidata.org/wiki/Q39809","display_name":"Marketing","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D062028","descriptor_name":"Bioprinting","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D066330","descriptor_name":"Printing, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1080/17460441.2018.1542427","doi":"https://doi.org/10.1080/17460441.2018.1542427","is_oa":false,"landing_page_url":"https://doi.org/10.1080/17460441.2018.1542427","pdf_url":null,"source":{"id":"https://openalex.org/S142541038","display_name":"Expert Opinion on Drug Discovery","issn_l":"1746-0441","issn":["1746-0441","1746-045X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Opinion on Drug Discovery","raw_type":"journal-article"},{"id":"pmid:30384781","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30384781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert opinion on drug discovery","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5843591","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6494715","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6494715","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6494715","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Expert Opin Drug Discov","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5843591","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6494715","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3135427962","display_name":"Immune-Cancer Cell Interactions in a 3D Bioprinted Tumor Microenvironment","funder_award_id":"R21CA224422","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7363977618","display_name":"CAREER: Hybrid Bioprinting of Engineered Vascularized Endocrine Tissues","funder_award_id":"1624515","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320719","display_name":"Department of Science and Technology, Ministry of Science and Technology, India","ror":"https://ror.org/0101xrq71"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":122,"referenced_works":["https://openalex.org/W1481145212","https://openalex.org/W1500036797","https://openalex.org/W1724038864","https://openalex.org/W1967987386","https://openalex.org/W1975469945","https://openalex.org/W1981779415","https://openalex.org/W1985133253","https://openalex.org/W1991551835","https://openalex.org/W1991914157","https://openalex.org/W1995237120","https://openalex.org/W1997647331","https://openalex.org/W2001041230","https://openalex.org/W2004669045","https://openalex.org/W2007003459","https://openalex.org/W2007050435","https://openalex.org/W2009798744","https://openalex.org/W2013133290","https://openalex.org/W2019425632","https://openalex.org/W2031135203","https://openalex.org/W2031503125","https://openalex.org/W2036453287","https://openalex.org/W2038962536","https://openalex.org/W2046451707","https://openalex.org/W2049826528","https://openalex.org/W2059116299","https://openalex.org/W2063333995","https://openalex.org/W2067424338","https://openalex.org/W2074103138","https://openalex.org/W2075889966","https://openalex.org/W2076922024","https://openalex.org/W2084261722","https://openalex.org/W2088660377","https://openalex.org/W2094712831","https://openalex.org/W2098594636","https://openalex.org/W2100081159","https://openalex.org/W2112226869","https://openalex.org/W2120772428","https://openalex.org/W2122920174","https://openalex.org/W2126416242","https://openalex.org/W2128151815","https://openalex.org/W2128423968","https://openalex.org/W2130119039","https://openalex.org/W2134951941","https://openalex.org/W2138108986","https://openalex.org/W2146493861","https://openalex.org/W2154555351","https://openalex.org/W2163149880","https://openalex.org/W2172143926","https://openalex.org/W2176403684","https://openalex.org/W2185345405","https://openalex.org/W2191030086","https://openalex.org/W2197557991","https://openalex.org/W2236643502","https://openalex.org/W2264718512","https://openalex.org/W2273267066","https://openalex.org/W2275842453","https://openalex.org/W2322888916","https://openalex.org/W2331628193","https://openalex.org/W2340849929","https://openalex.org/W2402500880","https://openalex.org/W2406723148","https://openalex.org/W2411101077","https://openalex.org/W2411123878","https://openalex.org/W2417310706","https://openalex.org/W2462042948","https://openalex.org/W2462818054","https://openalex.org/W2466156521","https://openalex.org/W2508326269","https://openalex.org/W2509523536","https://openalex.org/W2509960233","https://openalex.org/W2514830645","https://openalex.org/W2530360197","https://openalex.org/W2530373995","https://openalex.org/W2533859605","https://openalex.org/W2547330766","https://openalex.org/W2553928733","https://openalex.org/W2561624363","https://openalex.org/W2568275076","https://openalex.org/W2577215016","https://openalex.org/W2594061930","https://openalex.org/W2599863456","https://openalex.org/W2605174594","https://openalex.org/W2605311374","https://openalex.org/W2605827552","https://openalex.org/W2607618862","https://openalex.org/W2608847279","https://openalex.org/W2612781596","https://openalex.org/W2613582928","https://openalex.org/W2619272127","https://openalex.org/W2620300384","https://openalex.org/W2621963256","https://openalex.org/W2626725994","https://openalex.org/W2687530251","https://openalex.org/W2724969178","https://openalex.org/W2737554817","https://openalex.org/W2740750197","https://openalex.org/W2744396984","https://openalex.org/W2748286045","https://openalex.org/W2753231520","https://openalex.org/W2768294892","https://openalex.org/W2770298048","https://openalex.org/W2771920343","https://openalex.org/W2773114542","https://openalex.org/W2790169228","https://openalex.org/W2790244053","https://openalex.org/W2791017844","https://openalex.org/W2792087196","https://openalex.org/W2793826631","https://openalex.org/W2794458190","https://openalex.org/W2801546204","https://openalex.org/W2804098126","https://openalex.org/W2804566606","https://openalex.org/W2804715583","https://openalex.org/W2805187512","https://openalex.org/W2805190757","https://openalex.org/W2809205410","https://openalex.org/W2809220016","https://openalex.org/W2810302946","https://openalex.org/W2836385383","https://openalex.org/W2887275392","https://openalex.org/W2888887788","https://openalex.org/W2967431677"],"related_works":["https://openalex.org/W2612781596","https://openalex.org/W4383873197","https://openalex.org/W4399290236","https://openalex.org/W4402639186","https://openalex.org/W4385777692","https://openalex.org/W1189182196","https://openalex.org/W4281764013","https://openalex.org/W3197824736","https://openalex.org/W4386711618","https://openalex.org/W4407588914"],"abstract_inverted_index":{"Introduction:":[0],"Although":[1],"there":[2],"have":[3],"been":[4,161],"significant":[5],"contributions":[6],"from":[7,60],"the":[8,19,52,85,141,146,153,167,172],"pharmaceutical":[9],"industry":[10],"to":[11,50,63,100,149],"clinical":[12,40],"practice,":[13],"several":[14,164],"diseases":[15],"remain":[16],"unconquered,":[17],"with":[18,163],"discovery":[20,33,130],"of":[21,31,57,68,77,87,91,95,117,140,145,174],"new":[22],"drugs":[23],"remaining":[24],"a":[25,110,114],"paramount":[26],"objective.":[27],"The":[28,55,89,106],"actual":[29],"process":[30,53],"drug":[32,129],"involves":[34],"many":[35],"steps":[36],"including":[37],"pre-clinical":[38],"and":[39,46,80,121,135],"testing,":[41],"which":[42],"are":[43,137],"highly":[44],"time-":[45],"resource-consuming,":[47],"driving":[48],"researchers":[49],"improve":[51,101],"efficiency.":[54],"shift":[56],"modelling":[58],"technology":[59],"two-dimensions":[61],"(2D)":[62],"three-dimensions":[64],"(3D)":[65],"is":[66],"one":[67],"such":[69],"advancements.":[70],"3D":[71,102],"Models":[72],"allow":[73],"for":[74,93,124],"close":[75],"mimicry":[76],"cellular":[78],"interactions":[79],"tissue":[81,119],"microenvironments":[82],"thereby":[83],"improving":[84],"accuracy":[86],"results.":[88],"advent":[90],"bioprinting":[92],"fabrication":[94],"tissues":[96],"has":[97,148,159],"shown":[98],"potential":[99,126],"culture":[103],"models.Areas":[104],"covered:":[105],"present":[107],"review":[108],"provides":[109],"comprehensive":[111],"update":[112],"on":[113],"wide":[115],"range":[116],"bioprinted":[118,142],"models":[120,176],"appraise":[122],"them":[123],"their":[125],"use":[127],"in":[128,152],"research.Expert":[131],"opinion:":[132],"Efficiency,":[133],"reproducibility,":[134],"standardization":[136],"some":[138],"impediments":[139],"models.":[143],"Vascularization":[144],"constructs":[147],"be":[150,171],"addressed":[151],"near":[154],"future.":[155],"While":[156],"much":[157],"progress":[158],"already":[160],"made":[162],"seminal":[165],"works,":[166],"next":[168],"milestone":[169],"will":[170],"commercialization":[173],"these":[175],"after":[177],"due":[178],"regulatory":[179],"approval.":[180]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2018-11-09T00:00:00"}