{"id":"https://openalex.org/W2898513877","doi":"https://doi.org/10.1177/1756287218808496","title":"Criteria for indication and treatment modification in a cohort of patients with prostate cancer treated with hormone therapy","display_name":"Criteria for indication and treatment modification in a cohort of patients with prostate cancer treated with hormone therapy","publication_year":2018,"publication_date":"2018-10-24","ids":{"openalex":"https://openalex.org/W2898513877","doi":"https://doi.org/10.1177/1756287218808496","mag":"2898513877","pmid":"https://pubmed.ncbi.nlm.nih.gov/30574196","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6295785"},"language":"en","primary_location":{"id":"doi:10.1177/1756287218808496","doi":"https://doi.org/10.1177/1756287218808496","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1756287218808496","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/1756287218808496","source":{"id":"https://openalex.org/S105165982","display_name":"Therapeutic Advances in Urology","issn_l":"1756-2872","issn":["1756-2872","1756-2880"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutic Advances in Urology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://journals.sagepub.com/doi/pdf/10.1177/1756287218808496","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025728291","display_name":"Thierry Lebr\u00e9t","orcid":"https://orcid.org/0000-0002-8664-3861","observed_orcids":["https://orcid.org/0000-0002-8664-3861"]},"institutions":[{"id":"https://openalex.org/I195731000","display_name":"Universit\u00e9 de Versailles Saint-Quentin-en-Yvelines","ror":"https://ror.org/03mkjjy25","country_code":"FR","type":"education","lineage":["https://openalex.org/I195731000","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210156825","display_name":"H\u00f4pital Foch","ror":"https://ror.org/058td2q88","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210156825"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Thierry Lebret","raw_affiliation_strings":["H\u00f4pital Foch, Universit\u00e9 Versailles St. Quentin en Yvelines, Chef de Service Urologie et Transplantation R\u00e9nale, 40 Rue Worth, 92151 Suresnes, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00f4pital Foch, Universit\u00e9 Versailles St. Quentin en Yvelines, Chef de Service Urologie et Transplantation R\u00e9nale, 40 Rue Worth, 92151 Suresnes, France","institution_ids":["https://openalex.org/I195731000","https://openalex.org/I4210156825"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026135868","display_name":"A. Ruffion","orcid":"https://orcid.org/0000-0003-0512-3459","observed_orcids":["https://orcid.org/0000-0003-0512-3459"]},"institutions":[{"id":"https://openalex.org/I4210113288","display_name":"H\u00f4pital Lyon Sud","ror":"https://ror.org/023xgd207","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596","https://openalex.org/I4210113288"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Alain Ruffion","raw_affiliation_strings":["Centre Hospitalier Lyon Sud, Pierre B\u00e9nite, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre Hospitalier Lyon Sud, Pierre B\u00e9nite, France","institution_ids":["https://openalex.org/I4210113288"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012051564","display_name":"I. Latorzeff","orcid":"https://orcid.org/0000-0001-5935-5218","observed_orcids":["https://orcid.org/0000-0001-5935-5218"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Igor Latorzeff","raw_affiliation_strings":["Polyclinique du Parc, Toulouse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Polyclinique du Parc, Toulouse, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050255590","display_name":"Marc Zerbib","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marc Zerbib","raw_affiliation_strings":["H\u00f4pital Cochin, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00f4pital Cochin, Paris, France","institution_ids":["https://openalex.org/I4210092774"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jean-Luc Moreau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jean-Luc Moreau","raw_affiliation_strings":["Polyclinique Gentilly, Nancy, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Polyclinique Gentilly, Nancy, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107658789","display_name":"Dominique Rossi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115034","display_name":"H\u00f4pital Nord","ror":"https://ror.org/029a4pp87","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I21491767","https://openalex.org/I4210087487","https://openalex.org/I4210115034"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Dominique Rossi","raw_affiliation_strings":["H\u00f4pital Nord, Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00f4pital Nord, Marseille, France","institution_ids":["https://openalex.org/I4210115034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057866798","display_name":"Nathalie Pello-Leprince-Ringuet","orcid":"https://orcid.org/0009-0005-6843-925X","observed_orcids":["https://orcid.org/0009-0005-6843-925X"]},"institutions":[{"id":"https://openalex.org/I183367347","display_name":"Ipsen (France)","ror":"https://ror.org/00d801g55","country_code":"FR","type":"company","lineage":["https://openalex.org/I183367347"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nathalie Pello-Leprince-Ringuet","raw_affiliation_strings":["Ipsen Pharma, Boulogne-Billancourt, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ipsen Pharma, Boulogne-Billancourt, France","institution_ids":["https://openalex.org/I183367347"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104992180","display_name":"Val\u00e9rie Perrot","orcid":"https://orcid.org/0000-0002-5541-728X","observed_orcids":["https://orcid.org/0000-0002-5541-728X"]},"institutions":[{"id":"https://openalex.org/I183367347","display_name":"Ipsen (France)","ror":"https://ror.org/00d801g55","country_code":"FR","type":"company","lineage":["https://openalex.org/I183367347"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Val\u00e9rie Perrot","raw_affiliation_strings":["Ipsen Pharma, Boulogne-Billancourt, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ipsen Pharma, Boulogne-Billancourt, France","institution_ids":["https://openalex.org/I183367347"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028353199","display_name":"Christophe Hennequin","orcid":"https://orcid.org/0000-0002-8355-3801","observed_orcids":["https://orcid.org/0000-0002-8355-3801"]},"institutions":[{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christophe Hennequin","raw_affiliation_strings":["H\u00f4pital Saint-Louis, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00f4pital Saint-Louis, Paris, France","institution_ids":["https://openalex.org/I4210144610"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5025728291"],"corresponding_institution_ids":["https://openalex.org/I195731000","https://openalex.org/I4210156825"],"apc_list":{"value":2650,"currency":"USD","value_usd":2650},"apc_paid":{"value":2650,"currency":"USD","value_usd":2650},"fwci":0.2265,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.42028574,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"10","issue":"12","first_page":"365","last_page":"376"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.0066999997943639755,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9959999918937683},{"id":"https://openalex.org/keywords/androgen-deprivation-therapy","display_name":"androgen deprivation therapy","score":0.996999979019165},{"id":"https://openalex.org/keywords/gnrh-analogs","display_name":"GnRH analogues","score":0.906000018119812},{"id":"https://openalex.org/keywords/treatment-modification","display_name":"treatment modification","score":0.9139999747276306},{"id":"https://openalex.org/keywords/metastatic-prostate-cancer","display_name":"metastatic prostate cancer","score":0.8270000219345093},{"id":"https://openalex.org/keywords/locally-advanced-prostate-cancer","display_name":"locally advanced prostate cancer","score":0.9890000224113464},{"id":"https://openalex.org/keywords/predictive-factors","display_name":"predictive factors","score":0.8320000171661377},{"id":"https://openalex.org/keywords/urinary-symptoms","display_name":"urinary symptoms","score":0.640999972820282},{"id":"https://openalex.org/keywords/physician-specialty","display_name":"physician specialty","score":0.46700000762939453},{"id":"https://openalex.org/keywords/metastatic-stage","display_name":"metastatic stage","score":0.6309999823570251}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9445819854736328},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.6838486790657043},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.6728993058204651},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.6553049683570862},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5998164415359497},{"id":"https://openalex.org/C2777899217","wikidata":"https://www.wikidata.org/wiki/Q4759439","display_name":"Androgen deprivation therapy","level":4,"score":0.578464686870575},{"id":"https://openalex.org/C2780275930","wikidata":"https://www.wikidata.org/wiki/Q1628266","display_name":"Hormone therapy","level":4,"score":0.5440253019332886},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5281724333763123},{"id":"https://openalex.org/C2778311097","wikidata":"https://www.wikidata.org/wiki/Q5903784","display_name":"Hormonal therapy","level":4,"score":0.45176225900650024},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.42146414518356323},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.418582022190094},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.41428524255752563},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3458419442176819},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.32292139530181885},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.25448018312454224},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.15320268273353577}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1177/1756287218808496","doi":"https://doi.org/10.1177/1756287218808496","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1756287218808496","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/1756287218808496","source":{"id":"https://openalex.org/S105165982","display_name":"Therapeutic Advances in Urology","issn_l":"1756-2872","issn":["1756-2872","1756-2880"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutic Advances in Urology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5271139","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6295785","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:30574196","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30574196","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutic advances in urology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6295785","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6295785/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ther Adv Urol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:7a3cd625bbe2498c8274ea30896c7dc5","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/7a3cd625bbe2498c8274ea30896c7dc5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Therapeutic Advances in Urology, Vol 10 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1177/1756287218808496","doi":"https://doi.org/10.1177/1756287218808496","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1756287218808496","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/1756287218808496","source":{"id":"https://openalex.org/S105165982","display_name":"Therapeutic Advances in Urology","issn_l":"1756-2872","issn":["1756-2872","1756-2880"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutic Advances in Urology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320328455","display_name":"Ipsen","ror":"https://ror.org/00d801g55"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2898513877.pdf"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1597590095","https://openalex.org/W1823051973","https://openalex.org/W1976887636","https://openalex.org/W1991540374","https://openalex.org/W2081084828","https://openalex.org/W2100501133","https://openalex.org/W2108697501","https://openalex.org/W2117511763","https://openalex.org/W2126175123","https://openalex.org/W2127320853","https://openalex.org/W2135078918","https://openalex.org/W2142629844","https://openalex.org/W2144246081","https://openalex.org/W2150865892","https://openalex.org/W2164194457","https://openalex.org/W2208340908","https://openalex.org/W2214621962","https://openalex.org/W2235523093","https://openalex.org/W2339919763","https://openalex.org/W2419409011","https://openalex.org/W2511949746","https://openalex.org/W2751826273","https://openalex.org/W2794776069","https://openalex.org/W3023855930","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2598101089","https://openalex.org/W2211683473","https://openalex.org/W2522448115","https://openalex.org/W2991080206","https://openalex.org/W2601483519","https://openalex.org/W1579656422","https://openalex.org/W3129039703","https://openalex.org/W2099143876","https://openalex.org/W4402011315","https://openalex.org/W2461323638"],"abstract_inverted_index":{"Background:":[0],"No":[1],"published":[2],"studies":[3],"have":[4],"specifically":[5],"assessed":[6],"whether":[7],"treatment":[8,52,88,136,149,164,167,216],"modifications":[9],"to":[10,32,105,202],"androgen":[11],"deprivation":[12],"therapy":[13,42],"(ADT)":[14],"for":[15,84,130,139,213,266],"prostate":[16],"cancer":[17],"(PCa)":[18],"are":[19],"frequently":[20],"carried":[21,66],"out":[22,67],"in":[23,68,72,154,170,242,253,260],"routine":[24,69,261],"clinical":[25,70,262],"practice.":[26,263],"The":[27,94,133],"current":[28],"study":[29,64,119,239],"was":[30,65,97,137,168],"conducted":[31],"determine":[33],"what":[34],"proportion":[35,99],"of":[36,100,173,186,191,196,208,229,244,268,276],"patients":[37,101,114,174,246],"who":[38],"had":[39,50],"initiated":[40,138],"hormone":[41,46,108],"with":[43,75,90,102,156,247],"a":[44,91,103,194],"gonadotropin-releasing":[45],"(GnRH)":[47],"analogue":[48,135,182,198,215],"then":[49],"their":[51,106],"regimen":[53],"modified":[54,169,252],"during":[55,175],"the":[56,98,118,124,176,189,245,254,274],"first":[57,255],"24":[58],"months.":[59],"Methods:":[60],"A":[61,206],"prospective,":[62],"noninterventional":[63],"practice":[71],"France.":[73],"Patients":[74],"locally":[76,143,151],"advanced":[77,144,152,248],"or":[78,200,227],"metastatic":[79,140,220,271],"PCa":[80,141,145,153],"were":[81,115,218,270],"followed":[82],"up":[83],"2":[85,256],"years":[86,257],"after":[87,162,180,258],"initiation":[89,259],"GnRH":[92,134,181,197,204,214],"analogue.":[93,205],"primary":[95,125],"endpoint":[96,126],"modification":[104,192,217],"initial":[107],"therapy.":[109],"Results:":[110],"In":[111,184],"total,":[112],"1301":[113],"enrolled":[116],"into":[117],"by":[120],"204":[121],"physicians,":[122],"and":[123,159,232,273],"could":[127],"be":[128],"evaluated":[129],"891":[131],"patients.":[132],"(24.2%),":[142],"without":[146],"planned":[147],"local":[148,163],"(20.6%),":[150],"association":[155],"radiotherapy":[157],"(31.6%),":[158],"biochemical":[160],"recurrence":[161],"(21.4%).":[165],"Hormonal":[166],"43.8%":[171,243],"(390/891)":[172],"24-month":[177],"follow-up":[178],"period":[179],"initiation.":[183],"61.3%":[185],"cases":[187],"(239/390),":[188],"type":[190],"involved":[193],"change":[195],"formulation":[199],"switch":[201],"another":[203],"total":[207],"five":[209],"significant":[210],"predictive":[211],"factors":[212,265],"identified:":[219],"stage;":[221],"physician":[222,224],"sector;":[223],"speciality;":[225],"presence":[226],"absence":[228],"urinary":[230],"symptoms;":[231],"intermittent":[233,278],"versus":[234],"continuous":[235],"ADT.":[236],"Conclusions:":[237],"This":[238],"shows":[240],"that":[241],"PCa,":[249],"ADT":[250,269],"is":[251],"Predictive":[264],"alteration":[267],"stage":[272],"choice":[275],"an":[277],"schedule.":[279]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-11-02T00:00:00"}