{"id":"https://openalex.org/W2898087464","doi":"https://doi.org/10.1038/s41598-018-34532-2","title":"The indispensable contribution of s38 protein to ovarian-eggshell morphogenesis in Drosophila melanogaster","display_name":"The indispensable contribution of s38 protein to ovarian-eggshell morphogenesis in Drosophila melanogaster","publication_year":2018,"publication_date":"2018-10-25","ids":{"openalex":"https://openalex.org/W2898087464","doi":"https://doi.org/10.1038/s41598-018-34532-2","mag":"2898087464","pmid":"https://pubmed.ncbi.nlm.nih.gov/30382186","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6208399"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-018-34532-2","doi":"https://doi.org/10.1038/s41598-018-34532-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-34532-2","pdf_url":"https://www.nature.com/articles/s41598-018-34532-2.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-018-34532-2.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086251752","display_name":"Athanassios D. Velentzas","orcid":"https://orcid.org/0000-0002-9755-395X","observed_orcids":["https://orcid.org/0000-0002-9755-395X"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Athanassios D. Velentzas","raw_affiliation_strings":["Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece"],"raw_orcid":"https://orcid.org/0000-0002-9755-395X","affiliations":[{"raw_affiliation_string":"Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042242477","display_name":"Panagiotis D. Velentzas","orcid":"https://orcid.org/0000-0001-9552-8403","observed_orcids":["https://orcid.org/0000-0001-9552-8403"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]},{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR","US"],"is_corresponding":false,"raw_author_name":"Panagiotis D. Velentzas","raw_affiliation_strings":["Department of Cancer Biology, Medical School, University of Massachusetts, Worcester, Massachusetts (MA), USA","Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology, Medical School, University of Massachusetts, Worcester, Massachusetts (MA), USA","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062976470","display_name":"Stamatia A. Katarachia","orcid":"https://orcid.org/0000-0001-6924-8627","observed_orcids":["https://orcid.org/0000-0001-6924-8627"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Stamatia A. Katarachia","raw_affiliation_strings":["Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041216749","display_name":"Athanasios K. Anagnostopoulos","orcid":"https://orcid.org/0000-0001-5161-7850","observed_orcids":["https://orcid.org/0000-0001-5161-7850"]},"institutions":[{"id":"https://openalex.org/I4210093138","display_name":"Biomedical Research Foundation of the Academy of Athens","ror":"https://ror.org/00gban551","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093138"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Athanasios K. Anagnostopoulos","raw_affiliation_strings":["Systems Biology Center, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Biology Center, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece","institution_ids":["https://openalex.org/I4210093138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051754853","display_name":"Niki E. Sagioglou","orcid":"https://orcid.org/0000-0002-0712-8037","observed_orcids":["https://orcid.org/0000-0002-0712-8037"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Niki E. Sagioglou","raw_affiliation_strings":["Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5096004669","display_name":"Eleni Thanou","orcid":"https://orcid.org/0009-0003-5555-3630","observed_orcids":["https://orcid.org/0009-0003-5555-3630"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Eleni V. Thanou","raw_affiliation_strings":["Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008936585","display_name":"Maria M. Tsioka","orcid":"https://orcid.org/0000-0001-9798-2087","observed_orcids":["https://orcid.org/0000-0001-9798-2087"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Maria M. Tsioka","raw_affiliation_strings":["Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029656734","display_name":"Vassiliki Mpakou","orcid":"https://orcid.org/0000-0002-8850-884X","observed_orcids":["https://orcid.org/0000-0002-8850-884X"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Vassiliki E. Mpakou","raw_affiliation_strings":["Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065914721","display_name":"Zoe Kollia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210127711","display_name":"National Hellenic Research Foundation","ror":"https://ror.org/033m02g29","country_code":"GR","type":"funder","lineage":["https://openalex.org/I4210127711"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Zoe Kollia","raw_affiliation_strings":["Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation (NHRF), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation (NHRF), Athens, Greece","institution_ids":["https://openalex.org/I4210127711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087199218","display_name":"Vassilios E. Gavriil","orcid":"https://orcid.org/0000-0002-6612-8192","observed_orcids":["https://orcid.org/0000-0002-6612-8192"]},"institutions":[{"id":"https://openalex.org/I4210127711","display_name":"National Hellenic Research Foundation","ror":"https://ror.org/033m02g29","country_code":"GR","type":"funder","lineage":["https://openalex.org/I4210127711"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Vassilios E. Gavriil","raw_affiliation_strings":["Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation (NHRF), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation (NHRF), Athens, Greece","institution_ids":["https://openalex.org/I4210127711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063023126","display_name":"Issidora S. Papassideri","orcid":"https://orcid.org/0000-0002-9812-4495","observed_orcids":["https://orcid.org/0000-0002-9812-4495"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Issidora S. Papassideri","raw_affiliation_strings":["Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005389679","display_name":"George Th. Tsangaris","orcid":"https://orcid.org/0000-0002-5371-4758","observed_orcids":["https://orcid.org/0000-0002-5371-4758"]},"institutions":[{"id":"https://openalex.org/I4210093138","display_name":"Biomedical Research Foundation of the Academy of Athens","ror":"https://ror.org/00gban551","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093138"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"George Th. Tsangaris","raw_affiliation_strings":["Systems Biology Center, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Systems Biology Center, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece","institution_ids":["https://openalex.org/I4210093138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075093955","display_name":"A.C. Cefalas","orcid":"https://orcid.org/0000-0001-7913-5474","observed_orcids":["https://orcid.org/0000-0001-7913-5474"]},"institutions":[{"id":"https://openalex.org/I4210127711","display_name":"National Hellenic Research Foundation","ror":"https://ror.org/033m02g29","country_code":"GR","type":"funder","lineage":["https://openalex.org/I4210127711"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Alkiviadis-Constantinos Cefalas","raw_affiliation_strings":["Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation (NHRF), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation (NHRF), Athens, Greece","institution_ids":["https://openalex.org/I4210127711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023195532","display_name":"E. Sarantopoulou","orcid":"https://orcid.org/0000-0002-8530-5510","observed_orcids":["https://orcid.org/0000-0002-8530-5510"]},"institutions":[{"id":"https://openalex.org/I4210127711","display_name":"National Hellenic Research Foundation","ror":"https://ror.org/033m02g29","country_code":"GR","type":"funder","lineage":["https://openalex.org/I4210127711"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Evangelia Sarantopoulou","raw_affiliation_strings":["Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation (NHRF), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation (NHRF), Athens, Greece","institution_ids":["https://openalex.org/I4210127711"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023940657","display_name":"Dimitrios J. Stravopodis","orcid":"https://orcid.org/0000-0002-9535-2134","observed_orcids":["https://orcid.org/0000-0002-9535-2134"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Dimitrios J. Stravopodis","raw_affiliation_strings":["Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece. dstravop@biol.uoa.gr","Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece. dstravop@biol.uoa.gr","institution_ids":["https://openalex.org/I200777214"]},{"raw_affiliation_string":"Section of Cell Biology and Biophysics, Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5023940657"],"corresponding_institution_ids":["https://openalex.org/I200777214"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":0.3554,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.55487188,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"8","issue":"1","first_page":"16103","last_page":"16103"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.7588000297546387,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.7588000297546387,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.10409999638795853,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.07440000027418137,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chorion","display_name":"chorion","score":0.6050000190734863},{"id":"https://openalex.org/keywords/choriogenesis","display_name":"choriogenesis","score":0.9120000004768372},{"id":"https://openalex.org/keywords/ovarian-follicle-cells","display_name":"ovarian follicle cells","score":0.8009999990463257},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.8330000042915344},{"id":"https://openalex.org/keywords/endochorion","display_name":"endochorion","score":0.7329999804496765},{"id":"https://openalex.org/keywords/fertility","display_name":"fertility","score":0.5099999904632568},{"id":"https://openalex.org/keywords/rnai-knockdown","display_name":"RNAi knockdown","score":0.8420000076293945},{"id":"https://openalex.org/keywords/drosophila-melanogaster","display_name":"Drosophila melanogaster","score":0.8880000114440918}],"concepts":[{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.6991643905639648},{"id":"https://openalex.org/C2780104201","wikidata":"https://www.wikidata.org/wiki/Q130888","display_name":"Drosophila melanogaster","level":3,"score":0.6460503339767456},{"id":"https://openalex.org/C131934819","wikidata":"https://www.wikidata.org/wiki/Q135390","display_name":"Biogenesis","level":3,"score":0.5847501158714294},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.552064061164856},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5239903330802917},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.47259220480918884},{"id":"https://openalex.org/C2776041557","wikidata":"https://www.wikidata.org/wiki/Q3715451","display_name":"Drosophila (subgenus)","level":3,"score":0.457226425409317},{"id":"https://openalex.org/C203635412","wikidata":"https://www.wikidata.org/wiki/Q17007432","display_name":"Compartment (ship)","level":2,"score":0.4508237838745117},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.44146019220352173},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.42301270365715027},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.262206494808197},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13992929458618164},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.11613455414772034},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.0},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002451","descriptor_name":"Cell Compartmentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002823","descriptor_name":"Chorion","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D004527","descriptor_name":"Egg Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004528","descriptor_name":"Egg Shell","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004528","descriptor_name":"Egg Shell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004528","descriptor_name":"Egg Shell","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005298","descriptor_name":"Fertility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006080","descriptor_name":"Ovarian Follicle","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006080","descriptor_name":"Ovarian Follicle","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009024","descriptor_name":"Morphogenesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010063","descriptor_name":"Ovum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015536","descriptor_name":"Down-Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1038/s41598-018-34532-2","doi":"https://doi.org/10.1038/s41598-018-34532-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-34532-2","pdf_url":"https://www.nature.com/articles/s41598-018-34532-2.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5161387","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6208399","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6208399","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6208399","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmid:30382186","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30382186","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:a49045d6c5254abab766dd279e5bc670","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a49045d6c5254abab766dd279e5bc670","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)","raw_type":"article"},{"id":"pmh:oai:https://helios.eie.gr:10442/17427","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/10442/17427","pdf_url":null,"source":{"id":"https://openalex.org/S4306402248","display_name":"National Hellenic Research Foundation Helios Repository (National Hellenic Research Foundation)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210127711","host_organization_name":"National Hellenic Research Foundation","host_organization_lineage":["https://openalex.org/I4210127711"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, 8(1), (2018)","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1038/s41598-018-34532-2","doi":"https://doi.org/10.1038/s41598-018-34532-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-018-34532-2","pdf_url":"https://www.nature.com/articles/s41598-018-34532-2.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000089312","display_name":null,"funder_award_id":"NIH P40OD018537","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000862742","display_name":"Bloomington Drosophila Stock Center at Indiana University","funder_award_id":"P40OD018537","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2898087464.pdf","grobid_xml":"https://content.openalex.org/works/W2898087464.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W5459022","https://openalex.org/W1606360357","https://openalex.org/W1700345509","https://openalex.org/W1936346288","https://openalex.org/W1947528035","https://openalex.org/W1950596869","https://openalex.org/W1979351753","https://openalex.org/W1980072739","https://openalex.org/W1992592101","https://openalex.org/W1993676881","https://openalex.org/W1994263437","https://openalex.org/W2003527666","https://openalex.org/W2008286671","https://openalex.org/W2009673759","https://openalex.org/W2016992395","https://openalex.org/W2019788425","https://openalex.org/W2022315563","https://openalex.org/W2031606677","https://openalex.org/W2031649912","https://openalex.org/W2036974074","https://openalex.org/W2046193714","https://openalex.org/W2049865283","https://openalex.org/W2054172214","https://openalex.org/W2062378380","https://openalex.org/W2064708304","https://openalex.org/W2073857089","https://openalex.org/W2078986358","https://openalex.org/W2079508597","https://openalex.org/W2082451032","https://openalex.org/W2094774180","https://openalex.org/W2100581989","https://openalex.org/W2105442665","https://openalex.org/W2109897768","https://openalex.org/W2110643873","https://openalex.org/W2114692975","https://openalex.org/W2114870653","https://openalex.org/W2115867240","https://openalex.org/W2150972545","https://openalex.org/W2159464980","https://openalex.org/W2160904422","https://openalex.org/W2163355305","https://openalex.org/W2193703864","https://openalex.org/W2201927605","https://openalex.org/W2537916626","https://openalex.org/W2554959184","https://openalex.org/W2559001160","https://openalex.org/W2604174642","https://openalex.org/W2606420355","https://openalex.org/W2607339201","https://openalex.org/W2611946319","https://openalex.org/W2733871361","https://openalex.org/W2788063841","https://openalex.org/W2914395408","https://openalex.org/W4236498790","https://openalex.org/W7073574615"],"related_works":["https://openalex.org/W2537916626","https://openalex.org/W7098968197","https://openalex.org/W2071585109","https://openalex.org/W2025469097","https://openalex.org/W7074153387","https://openalex.org/W4404597777","https://openalex.org/W2049865283","https://openalex.org/W1994263437","https://openalex.org/W2034628178","https://openalex.org/W3126610902"],"abstract_inverted_index":{"Drosophila":[0],"chorion":[1,53],"represents":[2],"a":[3,26,124,136],"remarkable":[4],"model":[5],"system":[6],"for":[7],"the":[8,66,104,132],"in":[9,52,65,131,153],"vivo":[10],"study":[11],"of":[12,28,61,72,78,90,135],"complex":[13],"extracellular-matrix":[14],"architectures.":[15],"For":[16],"its":[17,47,154],"organization":[18],"and":[19,35,85,97,118,156],"structure,":[20],"s38":[21,62,91,111,121,145],"protein":[22,92,127],"is":[23,33,42,98],"considered":[24],"as":[25,123],"component":[27],"major":[29],"importance,":[30],"since":[31],"it":[32,142],"synthesized":[34],"secreted":[36],"during":[37],"early":[38],"choriogenesis.":[39],"However,":[40],"there":[41],"no":[43],"evidence":[44],"that":[45,58,144],"proves":[46],"essential,":[48],"or":[49],"redundant,":[50],"role":[51],"biogenesis.":[54],"Hence,":[55],"we":[56],"show":[57],"targeted":[59],"downregulation":[60],"protein,":[63],"specifically":[64],"ovarian":[67],"follicle-cell":[68],"compartment,":[69],"via":[70],"employment":[71],"an":[73],"RNAi-mediated":[74],"strategy,":[75],"causes":[76],"generation":[77],"diverse":[79],"dysmorphic":[80],"phenotypes,":[81],"regarding":[82],"eggshell's":[83],"regionally":[84],"radially":[86],"specialized":[87],"structures.":[88],"Downregulation":[89],"severely":[93],"impairs":[94],"fly's":[95],"fertility":[96],"unable":[99],"to":[100,115,150],"be":[101],"compensated":[102],"by":[103],"s36":[105],"homologous":[106],"family":[107],"member,":[108],"thus":[109],"unveiling":[110],"protein's":[112],"essential":[113],"contribution":[114],"chorion's":[116],"assembly":[117],"function.":[119],"Altogether,":[120],"acts":[122],"key":[125],"skeletal":[126],"being":[128],"critically":[129],"implicated":[130],"patterning":[133],"establishment":[134],"highly":[137],"structured":[138],"tripartite":[139],"endochorion.":[140],"Furthermore,":[141],"seems":[143],"loss":[146],"may":[147],"sensitize":[148],"choriogenesis":[149],"stochastic":[151],"variation":[152],"coordination":[155],"timing.":[157]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-11-02T00:00:00"}