{"id":"https://openalex.org/W2898075889","doi":"https://doi.org/10.1016/j.cell.2018.09.022","title":"Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens","display_name":"Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens","publication_year":2018,"publication_date":"2018-10-18","ids":{"openalex":"https://openalex.org/W2898075889","doi":"https://doi.org/10.1016/j.cell.2018.09.022","mag":"2898075889","pmid":"https://pubmed.ncbi.nlm.nih.gov/30343902","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6319269"},"language":"en","primary_location":{"id":"doi:10.1016/j.cell.2018.09.022","doi":"https://doi.org/10.1016/j.cell.2018.09.022","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cell.2018.09.022","pdf_url":"http://www.cell.com/article/S0092867418312340/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0092867418312340/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017642120","display_name":"Aleksandra Wroblewska","orcid":"https://orcid.org/0000-0003-2059-6158","observed_orcids":["https://orcid.org/0000-0003-2059-6158"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aleksandra Wroblewska","raw_affiliation_strings":["Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011248615","display_name":"Maxime Dhainaut","orcid":"https://orcid.org/0000-0003-3832-7095","observed_orcids":["https://orcid.org/0000-0003-3832-7095"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maxime Dhainaut","raw_affiliation_strings":["Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016370530","display_name":"Benjamin Ben-Zvi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin Ben-Zvi","raw_affiliation_strings":["Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062171528","display_name":"Samuel A. Rose","orcid":"https://orcid.org/0000-0001-9701-0050","observed_orcids":["https://orcid.org/0000-0001-9701-0050"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel A. Rose","raw_affiliation_strings":["Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Eun Sook Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eun Sook Park","raw_affiliation_strings":["Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080001526","display_name":"El-ad David Amir","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4390039328","display_name":"Tisch Cancer Institute","ror":"https://ror.org/0317dzj93","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1320796813","https://openalex.org/I4390039328","https://openalex.org/I98704320"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"El-Ad David Amir","raw_affiliation_strings":["Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I4390039328","https://openalex.org/I98704320"]},{"raw_affiliation_string":"Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I4390039328","https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011054247","display_name":"Anela Bektesevic","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anela Bektesevic","raw_affiliation_strings":["Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039833294","display_name":"Alessia Baccarini","orcid":"https://orcid.org/0000-0003-4727-0668","observed_orcids":["https://orcid.org/0000-0003-4727-0668"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alessia Baccarini","raw_affiliation_strings":["Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070354041","display_name":"Miriam M\u00e9rad","orcid":"https://orcid.org/0000-0002-4481-7827","observed_orcids":["https://orcid.org/0000-0002-4481-7827"]},"institutions":[{"id":"https://openalex.org/I4390039328","display_name":"Tisch Cancer Institute","ror":"https://ror.org/0317dzj93","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1320796813","https://openalex.org/I4390039328","https://openalex.org/I98704320"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miriam Merad","raw_affiliation_strings":["Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I4390039328","https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I4390039328","https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020454256","display_name":"Adeeb H Rahman","orcid":"https://orcid.org/0000-0002-8620-3161","observed_orcids":["https://orcid.org/0000-0002-8620-3161"]},"institutions":[{"id":"https://openalex.org/I4390039328","display_name":"Tisch Cancer Institute","ror":"https://ror.org/0317dzj93","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1320796813","https://openalex.org/I4390039328","https://openalex.org/I98704320"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adeeb H. Rahman","raw_affiliation_strings":["Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I4390039328","https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I4390039328","https://openalex.org/I98704320"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068360947","display_name":"Brian D. Brown","orcid":"https://orcid.org/0000-0002-3670-8778","observed_orcids":["https://orcid.org/0000-0002-3670-8778"]},"institutions":[{"id":"https://openalex.org/I4390039328","display_name":"Tisch Cancer Institute","ror":"https://ror.org/0317dzj93","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1320796813","https://openalex.org/I4390039328","https://openalex.org/I98704320"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Brian D. Brown","raw_affiliation_strings":["Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Diabetes Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: brian.brown@mssm.edu","Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Diabetes Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Diabetes Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: brian.brown@mssm.edu","institution_ids":["https://openalex.org/I4390039328","https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Diabetes Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA","institution_ids":["https://openalex.org/I4390039328","https://openalex.org/I98704320"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5068360947"],"corresponding_institution_ids":["https://openalex.org/I4390039328","https://openalex.org/I98704320"],"apc_list":{"value":11400,"currency":"USD","value_usd":11400},"apc_paid":null,"fwci":3.9023,"has_fulltext":false,"cited_by_count":164,"citation_normalized_percentile":{"value":0.9551044,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"175","issue":"4","first_page":"1141","last_page":"1155.e16"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.5702999830245972,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.5702999830245972,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.15690000355243683,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.03519999980926514,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crispr-screening","display_name":"CRISPR screen","score":0.796999990940094},{"id":"https://openalex.org/keywords/single-cell-phenotyping","display_name":"single-cell phenotyping","score":0.7670000195503235},{"id":"https://openalex.org/keywords/mass-cytometry","display_name":"mass cytometry","score":0.8149999976158142},{"id":"https://openalex.org/keywords/psmb8","display_name":"PSMB8","score":0.7440000176429749},{"id":"https://openalex.org/keywords/socs1","display_name":"SOCS1","score":0.9079999923706055},{"id":"https://openalex.org/keywords/pd-l1","display_name":"PD-L1","score":0.8519999980926514},{"id":"https://openalex.org/keywords/interferon-stimulated-genes","display_name":"interferon-stimulated genes","score":0.9409999847412109},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.5580000281333923}],"concepts":[{"id":"https://openalex.org/C98108389","wikidata":"https://www.wikidata.org/wiki/Q412563","display_name":"CRISPR","level":3,"score":0.8870989084243774},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8801692724227905},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5913225412368774},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5156958699226379},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.41930750012397766}],"mesh":[{"descriptor_ui":"D000074084","descriptor_name":"THP-1 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019169","descriptor_name":"Jurkat Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057809","descriptor_name":"HEK293 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D064113","descriptor_name":"CRISPR-Cas Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.cell.2018.09.022","doi":"https://doi.org/10.1016/j.cell.2018.09.022","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cell.2018.09.022","pdf_url":"http://www.cell.com/article/S0092867418312340/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},{"id":"pmid:30343902","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30343902","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6319269","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6319269/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cell","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.cell.2018.09.022","doi":"https://doi.org/10.1016/j.cell.2018.09.022","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cell.2018.09.022","pdf_url":"http://www.cell.com/article/S0092867418312340/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4016999900341034}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2338035120","display_name":"Sensor-seq: A genome-wide biological measure of microRNA activity.","funder_award_id":"R33CA182377","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3014955897","display_name":"Helios Mass Cytometer","funder_award_id":"1s10od023547-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5756200731","display_name":"Modulating Immunity to Nucleic Acids and Inducing Tolerance by Gene Transfer","funder_award_id":"R01AI113221","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7981559554","display_name":"Novel tools to maximize profiling of tissue and antigen specific immune dysregulation in allergy and inflammatory bowel disesase","funder_award_id":"U24AI118644","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8720743907","display_name":"Harnessing Csf-2 compartmentalized role on tissue resident phagocytes to uncouple anti-tumoral from pathological immunity induced by checkpoint inhibitors","funder_award_id":"R01CA190400","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000871755","display_name":"Defining Pathogenic Mechanisms and Therapeutic Opportunities for Langerhans Cell Histiocytosis","funder_award_id":"R01CA154947","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000906710","display_name":"Human anti-viral immune responses in tissues and circulation","funder_award_id":"U19AI128949","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320306621","display_name":"Belgian American Educational Foundation","ror":"https://ror.org/014rsed66"},{"id":"https://openalex.org/F4320314233","display_name":"Ovarian Cancer Research Fund Alliance","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2898075889.pdf"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1963130477","https://openalex.org/W1967350125","https://openalex.org/W1970170720","https://openalex.org/W1973401140","https://openalex.org/W1982729887","https://openalex.org/W2009283961","https://openalex.org/W2024626836","https://openalex.org/W2024827262","https://openalex.org/W2026592619","https://openalex.org/W2031211461","https://openalex.org/W2043565262","https://openalex.org/W2047977722","https://openalex.org/W2053129129","https://openalex.org/W2058955985","https://openalex.org/W2064815984","https://openalex.org/W2086196752","https://openalex.org/W2113432847","https://openalex.org/W2158333823","https://openalex.org/W2252568502","https://openalex.org/W2314851760","https://openalex.org/W2465860350","https://openalex.org/W2485511343","https://openalex.org/W2512065543","https://openalex.org/W2522313999","https://openalex.org/W2550962735","https://openalex.org/W2561508962","https://openalex.org/W2561754210","https://openalex.org/W2562947047","https://openalex.org/W2577994754","https://openalex.org/W2728365508","https://openalex.org/W2736476343","https://openalex.org/W2739492614","https://openalex.org/W2744743363","https://openalex.org/W2752426001","https://openalex.org/W2782124401","https://openalex.org/W2788425782","https://openalex.org/W2788483724","https://openalex.org/W2790853139","https://openalex.org/W2797766247","https://openalex.org/W2950261377","https://openalex.org/W6748883655"],"related_works":["https://openalex.org/W2900913719","https://openalex.org/W4416113866","https://openalex.org/W4390244727","https://openalex.org/W2577994754","https://openalex.org/W4403196249","https://openalex.org/W2803340220","https://openalex.org/W4311204473","https://openalex.org/W3211875080","https://openalex.org/W2939422961","https://openalex.org/W2899800897"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":23},{"year":2025,"cited_by_count":23},{"year":2024,"cited_by_count":24},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":26},{"year":2021,"cited_by_count":25},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2018-10-26T00:00:00"}
