{"id":"https://openalex.org/W2897282181","doi":"https://doi.org/10.1107/s2053230x18011706","title":"X-ray structure of Arthrobacter globiformis M30 ketose 3-epimerase for the production of D -allulose from D -fructose","display_name":"X-ray structure of Arthrobacter globiformis M30 ketose 3-epimerase for the production of D -allulose from D -fructose","publication_year":2018,"publication_date":"2018-09-21","ids":{"openalex":"https://openalex.org/W2897282181","doi":"https://doi.org/10.1107/s2053230x18011706","mag":"2897282181","pmid":"https://pubmed.ncbi.nlm.nih.gov/30279320","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6168773"},"language":"en","primary_location":{"id":"doi:10.1107/s2053230x18011706","doi":"https://doi.org/10.1107/s2053230x18011706","is_oa":false,"landing_page_url":"https://doi.org/10.1107/s2053230x18011706","pdf_url":null,"source":{"id":"https://openalex.org/S4210171526","display_name":"Acta Crystallographica Section F Structural Biology Communications","issn_l":"2053-230X","issn":["2053-230X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Crystallographica Section F Structural Biology Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6168773/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061597752","display_name":"Hiromi Yoshida","orcid":"https://orcid.org/0000-0001-8333-8215","observed_orcids":["https://orcid.org/0000-0001-8333-8215"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiromi Yoshida","raw_affiliation_strings":["Life Science Research Center and Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan","International Institute of Rare Sugar Research and Education, Kagawa University, Kagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Life Science Research Center and Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan","institution_ids":["https://openalex.org/I201933988"]},{"raw_affiliation_string":"International Institute of Rare Sugar Research and Education, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056496524","display_name":"Akihide Yoshihara","orcid":"https://orcid.org/0000-0002-7182-9612","observed_orcids":["https://orcid.org/0000-0002-7182-9612"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akihide Yoshihara","raw_affiliation_strings":["International Institute of Rare Sugar Research and Education, Kagawa University, Kagawa, Japan","Faculty of Agriculture, Kagawa University, 2393 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0795, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Institute of Rare Sugar Research and Education, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]},{"raw_affiliation_string":"Faculty of Agriculture, Kagawa University, 2393 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0795, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033447272","display_name":"Pushpa Kiran Gullapalli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139542","display_name":"Matsutani (Japan)","ror":"https://ror.org/034dpjp44","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210139542"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Pushpa Kiran Gullapalli","raw_affiliation_strings":["Matsutani Chemical Industry Co. Ltd, 5-3 Kita-Itami, Itami, Hyogo 664-8508, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matsutani Chemical Industry Co. Ltd, 5-3 Kita-Itami, Itami, Hyogo 664-8508, Japan","institution_ids":["https://openalex.org/I4210139542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101842890","display_name":"Kouhei Ohtani","orcid":"https://orcid.org/0009-0004-3513-0638","observed_orcids":["https://orcid.org/0009-0004-3513-0638"]},"institutions":[{"id":"https://openalex.org/I4210139542","display_name":"Matsutani (Japan)","ror":"https://ror.org/034dpjp44","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210139542"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kouhei Ohtani","raw_affiliation_strings":["Matsutani Chemical Industry Co. Ltd, 5-3 Kita-Itami, Itami, Hyogo 664-8508, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matsutani Chemical Industry Co. Ltd, 5-3 Kita-Itami, Itami, Hyogo 664-8508, Japan","institution_ids":["https://openalex.org/I4210139542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035420066","display_name":"Kazuya Akimitsu","orcid":"https://orcid.org/0000-0003-4374-1426","observed_orcids":["https://orcid.org/0000-0003-4374-1426"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuya Akimitsu","raw_affiliation_strings":["International Institute of Rare Sugar Research and Education, Kagawa University, Kagawa, Japan","Faculty of Agriculture, Kagawa University, 2393 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0795, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Institute of Rare Sugar Research and Education, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]},{"raw_affiliation_string":"Faculty of Agriculture, Kagawa University, 2393 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0795, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082327592","display_name":"Ken Izumori","orcid":"https://orcid.org/0000-0002-2883-853X","observed_orcids":["https://orcid.org/0000-0002-2883-853X"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ken Izumori","raw_affiliation_strings":["International Institute of Rare Sugar Research and Education, Kagawa University, Kagawa, Japan","Faculty of Agriculture, Kagawa University, 2393 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0795, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Institute of Rare Sugar Research and Education, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]},{"raw_affiliation_string":"Faculty of Agriculture, Kagawa University, 2393 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0795, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023503421","display_name":"S. Kamitori","orcid":"https://orcid.org/0000-0002-3950-3372","observed_orcids":["https://orcid.org/0000-0002-3950-3372"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigehiro Kamitori","raw_affiliation_strings":["Life Science Research Center and Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan","International Institute of Rare Sugar Research and Education, Kagawa University, Kagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Life Science Research Center and Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan","institution_ids":["https://openalex.org/I201933988"]},{"raw_affiliation_string":"International Institute of Rare Sugar Research and Education, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3520,"currency":"USD","value_usd":3520},"apc_paid":null,"fwci":1.2469,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.81668419,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"74","issue":"10","first_page":"669","last_page":"676"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fructose","display_name":"fructose","score":0.800000011920929},{"id":"https://openalex.org/keywords/l-ribulose","display_name":"L-ribulose","score":0.7149999737739563},{"id":"https://openalex.org/keywords/homotetramer","display_name":"homotetramer","score":0.8930000066757202},{"id":"https://openalex.org/keywords/enzyme-crystal-structure","display_name":"enzyme crystal structure","score":0.6620000004768372},{"id":"https://openalex.org/keywords/substrate-specificity","display_name":"substrate specificity","score":0.550000011920929},{"id":"https://openalex.org/keywords/allulose","display_name":"allulose","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C2780158061","wikidata":"https://www.wikidata.org/wiki/Q409108","display_name":"Ketose","level":4,"score":0.8634573221206665},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6364250183105469},{"id":"https://openalex.org/C2776970464","wikidata":"https://www.wikidata.org/wiki/Q122043","display_name":"Fructose","level":2,"score":0.5880981087684631},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.47885560989379883},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.37948527932167053},{"id":"https://openalex.org/C2776851017","wikidata":"https://www.wikidata.org/wiki/Q409079","display_name":"Aldose","level":3,"score":0.08896416425704956},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.07880014181137085}],"mesh":[{"descriptor_ui":"D000072756","descriptor_name":"Protein Conformation, alpha-Helical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072757","descriptor_name":"Protein Conformation, beta-Strand","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001173","descriptor_name":"Arthrobacter","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D001173","descriptor_name":"Arthrobacter","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002238","descriptor_name":"Carbohydrate Epimerases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002238","descriptor_name":"Carbohydrate Epimerases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002238","descriptor_name":"Carbohydrate Epimerases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005632","descriptor_name":"Fructose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005632","descriptor_name":"Fructose","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005822","descriptor_name":"Genetic Vectors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005822","descriptor_name":"Genetic Vectors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007661","descriptor_name":"Ketoses","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007661","descriptor_name":"Ketoses","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010429","descriptor_name":"Pentoses","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010429","descriptor_name":"Pentoses","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013379","descriptor_name":"Substrate Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020134","descriptor_name":"Catalytic Domain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040681","descriptor_name":"Structural Homology, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054730","descriptor_name":"Protein Interaction Domains and Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055503","descriptor_name":"Protein Multimerization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059128","descriptor_name":"Mesorhizobium","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D059128","descriptor_name":"Mesorhizobium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1107/s2053230x18011706","doi":"https://doi.org/10.1107/s2053230x18011706","is_oa":false,"landing_page_url":"https://doi.org/10.1107/s2053230x18011706","pdf_url":null,"source":{"id":"https://openalex.org/S4210171526","display_name":"Acta Crystallographica Section F Structural Biology Communications","issn_l":"2053-230X","issn":["2053-230X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Crystallographica Section F Structural Biology Communications","raw_type":"journal-article"},{"id":"pmid:30279320","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30279320","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta crystallographica. Section F, Structural biology communications","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6168773","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6168773/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Crystallogr F Struct Biol Commun","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:6168773","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6168773/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Crystallogr F Struct Biol Commun","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3630164674","display_name":"X-ray structure analysis of the enzyme for rare sugar production and elucidation of the mechanism of its thermal stability","funder_award_id":"16K07271","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1539796472","https://openalex.org/W1546896179","https://openalex.org/W1969996020","https://openalex.org/W1974680459","https://openalex.org/W1976488048","https://openalex.org/W1994272480","https://openalex.org/W2008470319","https://openalex.org/W2015477086","https://openalex.org/W2020148026","https://openalex.org/W2022058405","https://openalex.org/W2030517878","https://openalex.org/W2035503835","https://openalex.org/W2043462765","https://openalex.org/W2047326914","https://openalex.org/W2083370558","https://openalex.org/W2098176910","https://openalex.org/W2104284328","https://openalex.org/W2108921801","https://openalex.org/W2122208712","https://openalex.org/W2134202807","https://openalex.org/W2144081223","https://openalex.org/W2146080841","https://openalex.org/W2150163188","https://openalex.org/W2159211495","https://openalex.org/W2163679306","https://openalex.org/W2462836454","https://openalex.org/W2529219625","https://openalex.org/W2592681503"],"related_works":["https://openalex.org/W3147944555","https://openalex.org/W4293567355","https://openalex.org/W4402737435","https://openalex.org/W7128997177","https://openalex.org/W4399790970","https://openalex.org/W4385994274","https://openalex.org/W4394774555","https://openalex.org/W4283206316","https://openalex.org/W1976488048","https://openalex.org/W6977265524"],"abstract_inverted_index":{"The":[0,26,50,93],"X-ray":[1],"structure":[2,51,59,95],"of":[3,60,96,103,110,144,169],"ketose":[4],"3-epimerase":[5,18,64],"from":[6,171],"Arthrobacter":[7],"globiformis":[8],"M30,":[9],"which":[10,66],"was":[11,20,52,98],"previously":[12],"reported":[13],"to":[14,29,101,106,141],"be":[15],"a":[16,41,72,88,162],"D-allulose":[17,170],"(AgD-AE),":[19],"determined":[21],"at":[22],"1.96":[23],"\u00c5":[24],"resolution.":[25],"crystal":[27,77],"belonged":[28],"the":[30,58,82,107,135,142,145,167],"hexagonal":[31,76],"space":[32],"group":[33],"P":[34],"6":[35],"5":[36],"22,":[37],"with":[38,90],"unit-cell":[39],"parameters":[40],"=":[42,44,47],"b":[43],"103.98,":[45],"c":[46],"256.53":[48],"\u00c5.":[49],"solved":[53],"by":[54],"molecular":[55],"replacement":[56],"using":[57],"Mesorhizobium":[61],"loti":[62],"L-ribulose":[63,153],"(MlL-RE),":[65],"has":[67],"41%":[68],"sequence":[69],"identity,":[70],"as":[71],"search":[73],"model.":[74],"A":[75],"contained":[78],"two":[79],"molecules":[80],"in":[81,134],"asymmetric":[83],"unit,":[84],"and":[85,121,129,160],"AgD-AE":[86,97,120,128,147,157],"formed":[87],"homotetramer":[89],"twofold":[91],"symmetry.":[92],"overall":[94],"more":[99],"similar":[100],"that":[102,138],"MlL-RE":[104,122,130],"than":[105,154],"known":[108],"structures":[109],"D-psicose":[111],"(alternative":[112],"name":[113],"D-allulose)":[114],"3-epimerases":[115],"(D-PEs":[116],"or":[117],"D-AEs),":[118],"although":[119],"have":[123,131],"different":[124],"substrate":[125],"specificities.":[126],"Both":[127],"long":[132],"helices":[133],"C-terminal":[136],"region":[137],"would":[139],"contribute":[140],"stability":[143],"homotetramer.":[146],"showed":[148],"higher":[149],"enzymatic":[150],"activity":[151],"for":[152,166],"D-allulose;":[155],"however,":[156],"is":[158,161],"stable":[159],"unique":[163],"useful":[164],"enzyme":[165],"production":[168],"D-fructose.":[172]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-10-26T00:00:00"}