{"id":"https://openalex.org/W2896149404","doi":"https://doi.org/10.1016/j.jalz.2018.07.166","title":"P4\u2010343: USING SUBJECTIVE COGNITIVE DECLINE IN COMMUNITY\u2010DWELLING OLDER ADULTS TO IDENTIFY MCI AND DEMENTIA AT CROSS\u2010SECTION: RESULTS FROM THE EINSTEIN AGING STUDY","display_name":"P4\u2010343: USING SUBJECTIVE COGNITIVE DECLINE IN COMMUNITY\u2010DWELLING OLDER ADULTS TO IDENTIFY MCI AND DEMENTIA AT CROSS\u2010SECTION: RESULTS FROM THE EINSTEIN AGING STUDY","publication_year":2018,"publication_date":"2018-07-01","ids":{"openalex":"https://openalex.org/W2896149404","doi":"https://doi.org/10.1016/j.jalz.2018.07.166","mag":"2896149404"},"language":"en","primary_location":{"id":"doi:10.1016/j.jalz.2018.07.166","doi":"https://doi.org/10.1016/j.jalz.2018.07.166","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jalz.2018.07.166","pdf_url":null,"source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's &amp; Dementia","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107297270","display_name":"Laura A. Rabin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83041322","display_name":"Brooklyn College","ror":"https://ror.org/019k4jq75","country_code":"US","type":"education","lineage":["https://openalex.org/I83041322"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Laura Rabin","raw_affiliation_strings":["Brooklyn College of the City University of New York, Brooklyn, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brooklyn College of the City University of New York, Brooklyn, NY, USA","institution_ids":["https://openalex.org/I83041322"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101438003","display_name":"Cuiling Wang","orcid":"https://orcid.org/0000-0001-7806-1928","observed_orcids":["https://orcid.org/0000-0001-7806-1928"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cuiling Wang","raw_affiliation_strings":["Albert Einstein College of Medicine, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Albert Einstein College of Medicine, Bronx, NY, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040281324","display_name":"Carol A. Derby","orcid":"https://orcid.org/0000-0002-5657-4519","observed_orcids":["https://orcid.org/0000-0002-5657-4519"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carol A. Derby","raw_affiliation_strings":["Albert Einstein College of Medicine, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Albert Einstein College of Medicine, Bronx, NY, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000448269","display_name":"Richard B. Lipton","orcid":"https://orcid.org/0000-0003-2652-2897","observed_orcids":["https://orcid.org/0000-0003-2652-2897"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard B. Lipton","raw_affiliation_strings":["Albert Einstein College of Medicine, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Albert Einstein College of Medicine, Bronx, NY, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075873735","display_name":"Martin J. Sliwinski","orcid":"https://orcid.org/0000-0002-9611-7558","observed_orcids":["https://orcid.org/0000-0002-9611-7558"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin J. Sliwinski","raw_affiliation_strings":["Pennsylvania State University, University Park, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pennsylvania State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108463869","display_name":"Mindy Joy Katz","orcid":"https://orcid.org/0009-0004-7524-0292","observed_orcids":["https://orcid.org/0009-0004-7524-0292"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mindy J. Katz","raw_affiliation_strings":["Albert Einstein College of Medicine, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Albert Einstein College of Medicine, Bronx, NY, USA","institution_ids":["https://openalex.org/I129975664"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5107297270"],"corresponding_institution_ids":["https://openalex.org/I83041322"],"apc_list":{"value":4200,"currency":"USD","value_usd":4200},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14904585,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"7S_Part_30","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13077","display_name":"Cancer-related cognitive impairment studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12848","display_name":"Psychological Testing and Assessment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/subjective-cognitive-decline","display_name":"subjective cognitive decline","score":0.996999979019165},{"id":"https://openalex.org/keywords/mild-cognitive-impairment","display_name":"mild cognitive impairment","score":0.9539999961853027}],"concepts":[{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.7698651552200317},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5918430089950562},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.5118703246116638},{"id":"https://openalex.org/C6057870","wikidata":"https://www.wikidata.org/wiki/Q5141248","display_name":"Cognitive test","level":3,"score":0.5094490647315979},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.4759088456630707},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4539801776409149},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.45299339294433594},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.448343962430954},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.44402840733528137},{"id":"https://openalex.org/C143095724","wikidata":"https://www.wikidata.org/wiki/Q515895","display_name":"Odds","level":3,"score":0.4310775101184845},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.4281825125217438},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.397185355424881},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.35138386487960815},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3243522644042969},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.24090886116027832},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20762771368026733}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jalz.2018.07.166","doi":"https://doi.org/10.1016/j.jalz.2018.07.166","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jalz.2018.07.166","pdf_url":null,"source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's &amp; Dementia","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3090998762","https://openalex.org/W2893944382","https://openalex.org/W2980459142","https://openalex.org/W2193159112","https://openalex.org/W2282144130","https://openalex.org/W4390201804","https://openalex.org/W1970337983","https://openalex.org/W4205881010","https://openalex.org/W2765926959","https://openalex.org/W2897523834"],"abstract_inverted_index":{"Subjective":[0,450],"cognitive":[1,75,109,150,194,225,290,373,408,451],"decline":[2,374,452],"(SCD)":[3],"is":[4,46],"an":[5,326],"early":[6],"symptomatic":[7],"manifestation":[8],"of":[9,24,31,50,138,155,158,168,171,207,211,269,277,304,406,454],"Alzheimer's":[10,64,377,412],"disease":[11,65],"(AD).":[12],"Herein,":[13],"we":[14,299],"used":[15,78,98,132,295],"item":[16],"response":[17],"theory":[18],"(IRT)":[19],"to":[20,59,70,79,102,133,181,230,241,308,332,336,338],"improve":[21],"the":[22,28,104,123,135,165,233,302,421,458],"measurement":[23],"SCD":[25,32,107,139,159,218,246,284,305,320],"and":[26,73,94,108,175,213,238,253,265,272,292,312,400,404,411,416,427],"assess":[27],"cross-sectional":[29],"validity":[30],"for":[33,63,117,149,236,274,296,341,369,468,476],"distinguishing":[34,142,469,477],"clinical":[35,343],"diagnostic":[36,136,147,184],"groups":[37],"in":[38,141,245,314,345,375,414],"a":[39,47,61,81,204],"community-based":[40],"sample.1":[41],"The":[42,145,201,217],"Einstein":[43,422,459],"Aging":[44,423,460],"Study":[45],"longitudinal":[48],"cohort":[49],"diverse":[51],"older":[52,318],"adults":[53],"aged":[54],"\u2265":[55],"70.2":[56],"Seventeen":[57],"Consortium":[58],"Establish":[60],"registry":[62],"(CERAD)":[66],"self-report":[67],"items,":[68],"related":[69],"memory,":[71],"language,":[72],"other":[74],"domains,":[76],"were":[77,131,179,215,248,263],"create":[80],"single":[82],"composite":[83,219],"score":[84,220,247,285],"using":[85],"IRT":[86],"methodology.3":[87],"Covariates":[88],"included":[89],"age,":[90],"sex,":[91],"education,":[92,212],"race/ethnicity,":[93],"depressive":[95],"symptoms.":[96],"We":[97],"generalized":[99],"logit":[100],"models":[101],"evaluate":[103],"association":[105],"between":[106],"status":[110,151,226,291],"(normal,":[111],"MCI,":[112,280],"dementia)":[113],"at":[114,152,227],"baseline,":[115],"adjusting":[116],"covariates,":[118],"with":[119,224,289],"normal":[120,190,473,481],"cognition":[121,191],"as":[122,164,325],"reference":[124],"group.":[125],"Receiver":[126],"operating":[127],"Characteristic":[128],"(ROC)":[129],"curves":[130],"illustrate":[134],"accuracy":[137,148],"scores":[140,160,307],"two":[143],"states.":[144],"overall":[146,183],"each":[153],"pair":[154],"cut":[156,177,261,306],"points":[157,178,262],"was":[161,221,286],"then":[162],"calculated":[163],"total":[166],"probability":[167],"correct":[169,275],"classification":[170,276],"all":[172],"3":[173],"levels,":[174],"optimal":[176],"selected":[180],"maximize":[182],"accuracy.":[185],"Participants":[186],"(Table":[187,258],"1)":[188],"had":[189,203],"(n=1639),":[192],"mild":[193,407],"impairment":[195],"(MCI,":[196],"n=425),":[197],"or":[198],"dementia":[199,239,313,410,413,478],"(n=124).":[200],"sample":[202],"mean":[205],"age":[206],"78.9;":[208],"13.1":[209],"years":[210],"34%":[214],"non-white.":[216],"significantly":[222],"associated":[223,288],"baseline.":[228],"Relative":[229],"cognitively":[231,278,472,480],"normal,":[232,279],"odds":[234],"ratios":[235],"MCI":[237,311,470],"corresponding":[240],"1":[242],"unit":[243],"increase":[244],"5.58":[249],"(CI:":[250,255],"4.61-6.76,":[251],"p<.0001)":[252,257],"16.89":[254],"11.52-24.76,":[256],"2).":[259],"Optimal":[260],"-0.38":[264],"1.44,":[266],"yielding":[267],"probabilities":[268],"0.75,":[270],"0.75":[271],"0.52":[273],"dementia.":[281],"At":[282],"cross-section,":[283],"strongly":[287],"could":[293],"be":[294],"classification.":[297],"Next,":[298],"will":[300],"investigate":[301],"ability":[303],"predict":[309],"future":[310],"neuropsychologically":[315],"intact":[316],"community-dwelling":[317],"adults.":[319],"assessment":[321],"may":[322],"thus":[323],"serve":[324],"affordable,":[327],"non-invasive":[328],"first-line":[329],"screening":[330],"option":[331],"identify":[333],"those":[334],"likely":[335],"progress,":[337],"enrich":[339],"samples":[340],"preventive":[342],"trials":[344],"AD.":[346],"References:":[347],"1.":[348],"Jessen":[349],"F,":[350],"Amariglio":[351],"RE,":[352],"van":[353],"Boxtel":[354],"M,":[355,357,359,433,441,443],"Breteler":[356],"Ceccaldi":[358],"Chetelat":[360],"G,":[361],"\u2026":[362],"&":[363,444],"Wagner":[364],"M.":[365],"A":[366,418],"conceptual":[367],"framework":[368],"research":[370],"on":[371],"subjective":[372],"preclinical":[376],"disease.":[378],"Alzheimers":[379,463],"Dement":[380],"2014;10(6):844\u2013852.":[381],"2.":[382],"Katz":[383,432],"MJ,":[384],"Lipton":[385,438],"RB,":[386],"Hall":[387],"CB,":[388],"Zimmerman":[389,440],"ME,":[390],"Sanders":[391],"AE,":[392],"Verghese":[393],"J,":[394],"Dickson":[395],"DW,":[396],"Derby":[397,436],"CA.":[398],"Age":[399],"sex":[401],"specific":[402],"prevalence":[403],"incidence":[405],"impairment,":[409],"blacks":[415],"whites:":[417],"report":[419],"from":[420,457,471,479],"Study.":[424,461],"Alzheimer":[425],"Disease":[426],"Associated":[428],"Disorders.":[429],"2012;26(4):335.":[430],"3.":[431],"Wang":[434],"C,":[435,437],"R,":[439],"Sliwinski":[442],"Rabin":[445],"L.":[446],"(under":[447],"review,":[448],"2018).":[449],"prediction":[453],"mortality:":[455],"Results":[456],"J":[462],"Dis":[464],".":[465],"ROC":[466,474],"curve":[467,475]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2018-10-26T00:00:00"}