{"id":"https://openalex.org/W2895839872","doi":"https://doi.org/10.1016/j.bbadis.2018.10.019","title":"The impact of histone post-translational modifications in neurodegenerative diseases","display_name":"The impact of histone post-translational modifications in neurodegenerative diseases","publication_year":2018,"publication_date":"2018-10-20","ids":{"openalex":"https://openalex.org/W2895839872","doi":"https://doi.org/10.1016/j.bbadis.2018.10.019","mag":"2895839872","pmid":"https://pubmed.ncbi.nlm.nih.gov/30352259","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6475498"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbadis.2018.10.019","doi":"https://doi.org/10.1016/j.bbadis.2018.10.019","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbadis.2018.10.019","pdf_url":"https://www.sciencedirect.com/science/article/pii/S092544391830396X/pdf","source":{"id":"https://openalex.org/S4210173099","display_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","issn_l":"0925-4439","issn":["0925-4439","1879-260X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S092544391830396X/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064368205","display_name":"Samantha N. Cobos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121847817","display_name":"The Graduate Center, CUNY","ror":"https://ror.org/00awd9g61","country_code":"US","type":"education","lineage":["https://openalex.org/I121847817"]},{"id":"https://openalex.org/I174216632","display_name":"City University of New York","ror":"https://ror.org/00453a208","country_code":"US","type":"education","lineage":["https://openalex.org/I174216632"]},{"id":"https://openalex.org/I83041322","display_name":"Brooklyn College","ror":"https://ror.org/019k4jq75","country_code":"US","type":"education","lineage":["https://openalex.org/I83041322"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samantha N. Cobos","raw_affiliation_strings":["Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States; Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States","Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States","Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States; Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States","institution_ids":["https://openalex.org/I121847817","https://openalex.org/I174216632","https://openalex.org/I83041322"]},{"raw_affiliation_string":"Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States","institution_ids":["https://openalex.org/I83041322"]},{"raw_affiliation_string":"Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States","institution_ids":["https://openalex.org/I121847817","https://openalex.org/I174216632"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085486847","display_name":"Seth A. Bennett","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121847817","display_name":"The Graduate Center, CUNY","ror":"https://ror.org/00awd9g61","country_code":"US","type":"education","lineage":["https://openalex.org/I121847817"]},{"id":"https://openalex.org/I174216632","display_name":"City University of New York","ror":"https://ror.org/00453a208","country_code":"US","type":"education","lineage":["https://openalex.org/I174216632"]},{"id":"https://openalex.org/I83041322","display_name":"Brooklyn College","ror":"https://ror.org/019k4jq75","country_code":"US","type":"education","lineage":["https://openalex.org/I83041322"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Seth A. Bennett","raw_affiliation_strings":["Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States; Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States","Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States","Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States; Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States","institution_ids":["https://openalex.org/I121847817","https://openalex.org/I174216632","https://openalex.org/I83041322"]},{"raw_affiliation_string":"Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States","institution_ids":["https://openalex.org/I83041322"]},{"raw_affiliation_string":"Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016, United States","institution_ids":["https://openalex.org/I121847817","https://openalex.org/I174216632"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029295305","display_name":"Mariana P. Torrente","orcid":"https://orcid.org/0000-0001-8220-2228","observed_orcids":["https://orcid.org/0000-0001-8220-2228"]},"institutions":[{"id":"https://openalex.org/I121847817","display_name":"The Graduate Center, CUNY","ror":"https://ror.org/00awd9g61","country_code":"US","type":"education","lineage":["https://openalex.org/I121847817"]},{"id":"https://openalex.org/I174216632","display_name":"City University of New York","ror":"https://ror.org/00453a208","country_code":"US","type":"education","lineage":["https://openalex.org/I174216632"]},{"id":"https://openalex.org/I83041322","display_name":"Brooklyn College","ror":"https://ror.org/019k4jq75","country_code":"US","type":"education","lineage":["https://openalex.org/I83041322"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mariana P. Torrente","raw_affiliation_strings":["Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States; Ph.D. Programs in Chemistry, Biochemistry, and Biology, The Graduate Center of the City University of New York, New York 10016, United States. Electronic address: mariana.torrente@brooklyn.cuny.edu","Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States","Ph.D. Programs in Chemistry, Biochemistry, and Biology, The Graduate Center of the City University of New York, New York 10016, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States; Ph.D. Programs in Chemistry, Biochemistry, and Biology, The Graduate Center of the City University of New York, New York 10016, United States. Electronic address: mariana.torrente@brooklyn.cuny.edu","institution_ids":["https://openalex.org/I121847817","https://openalex.org/I174216632","https://openalex.org/I83041322"]},{"raw_affiliation_string":"Chemistry Department of Brooklyn College, Brooklyn, New York 11210, United States","institution_ids":["https://openalex.org/I83041322"]},{"raw_affiliation_string":"Ph.D. Programs in Chemistry, Biochemistry, and Biology, The Graduate Center of the City University of New York, New York 10016, United States","institution_ids":["https://openalex.org/I121847817","https://openalex.org/I174216632"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5029295305"],"corresponding_institution_ids":["https://openalex.org/I121847817","https://openalex.org/I174216632","https://openalex.org/I83041322"],"apc_list":{"value":4010,"currency":"USD","value_usd":4010},"apc_paid":null,"fwci":0.5152,"has_fulltext":true,"cited_by_count":54,"citation_normalized_percentile":{"value":0.46398764,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"1865","issue":"8","first_page":"1982","last_page":"1991"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.43479999899864197,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.43479999899864197,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.23849999904632568,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.10530000180006027,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/histone-modifications","display_name":"histone modifications","score":1.0},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.9570000171661377},{"id":"https://openalex.org/keywords/epigenetics","display_name":"epigenetics","score":0.8460000157356262},{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"amyotrophic lateral sclerosis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/frontotemporal-dementia","display_name":"frontotemporal dementia","score":1.0},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":1.0},{"id":"https://openalex.org/keywords/ataxia","display_name":"ataxia","score":0.9509999752044678},{"id":"https://openalex.org/keywords/epigenomic-landscape","display_name":"epigenomic landscape","score":0.7689999938011169},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.8159999847412109}],"concepts":[{"id":"https://openalex.org/C2778641062","wikidata":"https://www.wikidata.org/wiki/Q18592","display_name":"Frontotemporal dementia","level":4,"score":0.7167199850082397},{"id":"https://openalex.org/C2780596555","wikidata":"https://www.wikidata.org/wiki/Q206901","display_name":"Amyotrophic lateral sclerosis","level":3,"score":0.6854444742202759},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.6835816502571106},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6811614036560059},{"id":"https://openalex.org/C121912465","wikidata":"https://www.wikidata.org/wiki/Q3589153","display_name":"Epigenomics","level":5,"score":0.6393216252326965},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6047684550285339},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.49134913086891174},{"id":"https://openalex.org/C2776925932","wikidata":"https://www.wikidata.org/wiki/Q1755122","display_name":"Neurodegeneration","level":3,"score":0.4819590747356415},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4200788736343384},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4087812006473541},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.38404393196105957},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3759263753890991},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.35713499784469604},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19932320713996887},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.16372469067573547},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11579862236976624},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.09956830739974976}],"mesh":[{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001259","descriptor_name":"Ataxia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001259","descriptor_name":"Ataxia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001259","descriptor_name":"Ataxia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001259","descriptor_name":"Ataxia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011499","descriptor_name":"Protein Processing, Post-Translational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011499","descriptor_name":"Protein Processing, Post-Translational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011499","descriptor_name":"Protein Processing, Post-Translational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011499","descriptor_name":"Protein Processing, Post-Translational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019636","descriptor_name":"Neurodegenerative Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019636","descriptor_name":"Neurodegenerative Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019636","descriptor_name":"Neurodegenerative Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019636","descriptor_name":"Neurodegenerative Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D042421","descriptor_name":"Histone Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D042421","descriptor_name":"Histone Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D042421","descriptor_name":"Histone Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D042421","descriptor_name":"Histone Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057180","descriptor_name":"Frontotemporal Dementia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D057180","descriptor_name":"Frontotemporal Dementia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D057180","descriptor_name":"Frontotemporal Dementia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D057180","descriptor_name":"Frontotemporal Dementia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bbadis.2018.10.019","doi":"https://doi.org/10.1016/j.bbadis.2018.10.019","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbadis.2018.10.019","pdf_url":"https://www.sciencedirect.com/science/article/pii/S092544391830396X/pdf","source":{"id":"https://openalex.org/S4210173099","display_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","issn_l":"0925-4439","issn":["0925-4439","1879-260X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","raw_type":"journal-article"},{"id":"pmid:30352259","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30352259","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta. Molecular basis of disease","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6475498","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6475498","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biochim Biophys Acta Mol Basis Dis","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.bbadis.2018.10.019","doi":"https://doi.org/10.1016/j.bbadis.2018.10.019","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbadis.2018.10.019","pdf_url":"https://www.sciencedirect.com/science/article/pii/S092544391830396X/pdf","source":{"id":"https://openalex.org/S4210173099","display_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","issn_l":"0925-4439","issn":["0925-4439","1879-260X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6000000238418579}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2662639051","display_name":null,"funder_award_id":"K22NS09131401","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2970918236","display_name":null,"funder_award_id":"K22NS09131401","funder_id":"https://openalex.org/F4320309102","funder_display_name":"City University of New York"},{"id":"https://openalex.org/G3228496257","display_name":null,"funder_award_id":"K22NS091314","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G6912881566","display_name":null,"funder_award_id":"K22 NS09131401","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320309102","display_name":"City University of New York","ror":"https://ror.org/00453a208"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F8373437238","display_name":"Brooklyn College","ror":"https://ror.org/019k4jq75"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2895839872.pdf","grobid_xml":"https://content.openalex.org/works/W2895839872.grobid-xml"},"referenced_works_count":157,"referenced_works":["https://openalex.org/W87918927","https://openalex.org/W192122200","https://openalex.org/W318511950","https://openalex.org/W1012257715","https://openalex.org/W1493846190","https://openalex.org/W1519439387","https://openalex.org/W1568991583","https://openalex.org/W1572679174","https://openalex.org/W1852828105","https://openalex.org/W1966900987","https://openalex.org/W1970687029","https://openalex.org/W1972097907","https://openalex.org/W1976626368","https://openalex.org/W1977252372","https://openalex.org/W1977399503","https://openalex.org/W1980764464","https://openalex.org/W1985460799","https://openalex.org/W1987105053","https://openalex.org/W1990916340","https://openalex.org/W1991660507","https://openalex.org/W1991667131","https://openalex.org/W1999018495","https://openalex.org/W2003205286","https://openalex.org/W2004415828","https://openalex.org/W2005900086","https://openalex.org/W2007086697","https://openalex.org/W2008761871","https://openalex.org/W2009858080","https://openalex.org/W2010029946","https://openalex.org/W2015416439","https://openalex.org/W2016915299","https://openalex.org/W2023590402","https://openalex.org/W2024351685","https://openalex.org/W2026340703","https://openalex.org/W2027720028","https://openalex.org/W2030382481","https://openalex.org/W2031087599","https://openalex.org/W2031964319","https://openalex.org/W2036253193","https://openalex.org/W2036698519","https://openalex.org/W2039294533","https://openalex.org/W2040233440","https://openalex.org/W2040375560","https://openalex.org/W2040506727","https://openalex.org/W2041336616","https://openalex.org/W2041922475","https://openalex.org/W2041964860","https://openalex.org/W2044463545","https://openalex.org/W2045151039","https://openalex.org/W2050644483","https://openalex.org/W2051186583","https://openalex.org/W2054365867","https://openalex.org/W2060076138","https://openalex.org/W2061144778","https://openalex.org/W2063460322","https://openalex.org/W2065516118","https://openalex.org/W2068845666","https://openalex.org/W2070616147","https://openalex.org/W2071591138","https://openalex.org/W2072516425","https://openalex.org/W2073073462","https://openalex.org/W2076376940","https://openalex.org/W2077311804","https://openalex.org/W2078973396","https://openalex.org/W2080719230","https://openalex.org/W2083245183","https://openalex.org/W2086188566","https://openalex.org/W2088872333","https://openalex.org/W2089423734","https://openalex.org/W2089574993","https://openalex.org/W2094998522","https://openalex.org/W2095184629","https://openalex.org/W2095884976","https://openalex.org/W2096464945","https://openalex.org/W2099403861","https://openalex.org/W2100252302","https://openalex.org/W2102997433","https://openalex.org/W2104047605","https://openalex.org/W2106206610","https://openalex.org/W2110002004","https://openalex.org/W2111796925","https://openalex.org/W2115670698","https://openalex.org/W2117099883","https://openalex.org/W2119943579","https://openalex.org/W2120481130","https://openalex.org/W2121264285","https://openalex.org/W2123257432","https://openalex.org/W2124161762","https://openalex.org/W2126569879","https://openalex.org/W2126684428","https://openalex.org/W2127081697","https://openalex.org/W2127861463","https://openalex.org/W2128206335","https://openalex.org/W2129286776","https://openalex.org/W2130441789","https://openalex.org/W2132881915","https://openalex.org/W2136388422","https://openalex.org/W2139232339","https://openalex.org/W2139384923","https://openalex.org/W2139871895","https://openalex.org/W2140210955","https://openalex.org/W2140937256","https://openalex.org/W2143658931","https://openalex.org/W2144925005","https://openalex.org/W2145929363","https://openalex.org/W2147250720","https://openalex.org/W2147524392","https://openalex.org/W2148194691","https://openalex.org/W2148641246","https://openalex.org/W2149591661","https://openalex.org/W2150523249","https://openalex.org/W2150656456","https://openalex.org/W2153825225","https://openalex.org/W2154737306","https://openalex.org/W2154923417","https://openalex.org/W2154945114","https://openalex.org/W2154969830","https://openalex.org/W2155418687","https://openalex.org/W2155725346","https://openalex.org/W2157111350","https://openalex.org/W2158155007","https://openalex.org/W2158787641","https://openalex.org/W2159556459","https://openalex.org/W2161688011","https://openalex.org/W2164373366","https://openalex.org/W2164956436","https://openalex.org/W2167678675","https://openalex.org/W2170754752","https://openalex.org/W2186898572","https://openalex.org/W2247278173","https://openalex.org/W2272042925","https://openalex.org/W2296809607","https://openalex.org/W2342980451","https://openalex.org/W2396794808","https://openalex.org/W2401805576","https://openalex.org/W2407766408","https://openalex.org/W2412429117","https://openalex.org/W2418484636","https://openalex.org/W2514975062","https://openalex.org/W2597921152","https://openalex.org/W2618807644","https://openalex.org/W2735741666","https://openalex.org/W2736440927","https://openalex.org/W2739174192","https://openalex.org/W2774884271","https://openalex.org/W2785225651","https://openalex.org/W2787234767","https://openalex.org/W2792275657","https://openalex.org/W2921518941","https://openalex.org/W2981414979","https://openalex.org/W2989931874","https://openalex.org/W4211044101","https://openalex.org/W4211201144","https://openalex.org/W4246230178","https://openalex.org/W4300821084","https://openalex.org/W6643479197","https://openalex.org/W6827623003"],"related_works":["https://openalex.org/W4402528698","https://openalex.org/W2774884271","https://openalex.org/W2896272078","https://openalex.org/W2922926903","https://openalex.org/W2036187962","https://openalex.org/W4415967581","https://openalex.org/W2245053929","https://openalex.org/W2142278633","https://openalex.org/W2558390068","https://openalex.org/W3081649146"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":5}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2018-10-26T00:00:00"}