{"id":"https://openalex.org/W2894469660","doi":"https://doi.org/10.1021/acsami.8b10233","title":"Aligning Synthetic Hippocampal Neural Circuits via Self-Rolled-Up Silicon Nitride Microtube Arrays","display_name":"Aligning Synthetic Hippocampal Neural Circuits via Self-Rolled-Up Silicon Nitride Microtube Arrays","publication_year":2018,"publication_date":"2018-09-25","ids":{"openalex":"https://openalex.org/W2894469660","doi":"https://doi.org/10.1021/acsami.8b10233","mag":"2894469660","pmid":"https://pubmed.ncbi.nlm.nih.gov/30251826"},"language":"en","primary_location":{"id":"doi:10.1021/acsami.8b10233","doi":"https://doi.org/10.1021/acsami.8b10233","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsami.8b10233","pdf_url":null,"source":{"id":"https://openalex.org/S164001016","display_name":"ACS Applied Materials & Interfaces","issn_l":"1944-8244","issn":["1944-8244","1944-8252"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Applied Materials & Interfaces","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026845170","display_name":"Olivia V. Cangellaris","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olivia V. Cangellaris","raw_affiliation_strings":["Department of Bioengineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","Medical Scholars Program, University of Illinois College of Medicine at Urbana\u2212Champaign, Urbana, Illinois 61801, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Medical Scholars Program, University of Illinois College of Medicine at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066493672","display_name":"Elise A. Corbin","orcid":"https://orcid.org/0000-0003-2373-0420","observed_orcids":["https://orcid.org/0000-0003-2373-0420"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elise A. Corbin","raw_affiliation_strings":["Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","Department of Bioengineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Bioengineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027468275","display_name":"Paul J. Froeter","orcid":"https://orcid.org/0009-0009-6046-0600","observed_orcids":["https://orcid.org/0009-0009-6046-0600"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul Froeter","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","Micro and Nanotechnology Laboratory, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Micro and Nanotechnology Laboratory, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034447731","display_name":"Julian A. Michaels","orcid":"https://orcid.org/0000-0002-7631-4036","observed_orcids":["https://orcid.org/0000-0002-7631-4036"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julian A. Michaels","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","Micro and Nanotechnology Laboratory, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Micro and Nanotechnology Laboratory, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100763046","display_name":"Xiuling Li","orcid":"https://orcid.org/0000-0003-3698-5182","observed_orcids":["https://orcid.org/0000-0003-3698-5182","https://orcid.org/0000-0002-9631-7920","https://orcid.org/0000-0001-5404-4242"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiuling Li","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","Micro and Nanotechnology Laboratory, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Micro and Nanotechnology Laboratory, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039332578","display_name":"Martha Ulbrick Gillette","orcid":"https://orcid.org/0000-0003-3645-2626","observed_orcids":["https://orcid.org/0000-0003-3645-2626"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Martha U. Gillette","raw_affiliation_strings":["Department of Bioengineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States"],"raw_orcid":"https://orcid.org/0000-0003-3645-2626","affiliations":[{"raw_affiliation_string":"Department of Bioengineering, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","institution_ids":["https://openalex.org/I157725225"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5039332578"],"corresponding_institution_ids":["https://openalex.org/I157725225"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.3414,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.50255959,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"10","issue":"42","first_page":"35705","last_page":"35714"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.7612000107765198,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.7612000107765198,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.21119999885559082,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.006899999920278788,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hippocampal-neurons","display_name":"hippocampal neurons","score":0.8970000147819519},{"id":"https://openalex.org/keywords/neurite-alignment","display_name":"neurite alignment","score":0.847000002861023},{"id":"https://openalex.org/keywords/silicon-nitride","display_name":"silicon nitride","score":0.7519999742507935},{"id":"https://openalex.org/keywords/nerve-regeneration","display_name":"nerve regeneration","score":0.6100000143051147},{"id":"https://openalex.org/keywords/neuroengineering","display_name":"neural engineering","score":0.5189999938011169}],"concepts":[{"id":"https://openalex.org/C113246987","wikidata":"https://www.wikidata.org/wiki/Q1534415","display_name":"Neurite","level":3,"score":0.8204583525657654},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.7229650020599365},{"id":"https://openalex.org/C2780594696","wikidata":"https://www.wikidata.org/wiki/Q1127402","display_name":"Neural tube","level":3,"score":0.6251328587532043},{"id":"https://openalex.org/C118403218","wikidata":"https://www.wikidata.org/wiki/Q43283","display_name":"Biological neural network","level":2,"score":0.6155282855033875},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.6142252087593079},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4893014132976532},{"id":"https://openalex.org/C134146338","wikidata":"https://www.wikidata.org/wiki/Q1815901","display_name":"Electronic circuit","level":2,"score":0.488412082195282},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4271841049194336},{"id":"https://openalex.org/C95967509","wikidata":"https://www.wikidata.org/wiki/Q1952355","display_name":"Multielectrode array","level":4,"score":0.41026079654693604},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.39549165964126587},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.3329991102218628},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20250141620635986},{"id":"https://openalex.org/C111670793","wikidata":"https://www.wikidata.org/wiki/Q16979465","display_name":"Microelectrode","level":3,"score":0.13075101375579834},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.11242640018463135},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.10487306118011475},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.10114029049873352},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.09645071625709534},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.08568048477172852},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009415","descriptor_name":"Nerve Net","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016501","descriptor_name":"Neurites","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016501","descriptor_name":"Neurites","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017655","descriptor_name":"Silicon Compounds","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055616","descriptor_name":"Microtechnology","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1021/acsami.8b10233","doi":"https://doi.org/10.1021/acsami.8b10233","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsami.8b10233","pdf_url":null,"source":{"id":"https://openalex.org/S164001016","display_name":"ACS Applied Materials & Interfaces","issn_l":"1944-8244","issn":["1944-8244","1944-8252"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Applied Materials & Interfaces","raw_type":"journal-article"},{"id":"pmid:30251826","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30251826","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS applied materials & interfaces","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3702938933","display_name":"PROGRAMMING FUNCTION VIA SOFT MATERIALS","funder_award_id":"DEFG0207ER46471","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G4035684527","display_name":null,"funder_award_id":"0939511","funder_id":"https://openalex.org/F4320337390","funder_display_name":"Division of Chemical, Bioengineering, Environmental, and Transport Systems"},{"id":"https://openalex.org/G6825808186","display_name":null,"funder_award_id":"ECCS 1309375","funder_id":"https://openalex.org/F4320337392","funder_display_name":"Division of Electrical, Communications and Cyber Systems"},{"id":"https://openalex.org/G8528073851","display_name":null,"funder_award_id":"DGE-0903622","funder_id":"https://openalex.org/F4320337368","funder_display_name":"Division of Graduate Education"}],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320312065","display_name":"University of Illinois System","ror":"https://ror.org/05e94g991"},{"id":"https://openalex.org/F4320332222","display_name":"University of Illinois at Urbana-Champaign","ror":"https://ror.org/047426m28"},{"id":"https://openalex.org/F4320337368","display_name":"Division of Graduate Education","ror":"https://ror.org/00whkrf32"},{"id":"https://openalex.org/F4320337390","display_name":"Division of Chemical, Bioengineering, Environmental, and Transport Systems","ror":"https://ror.org/0471zv972"},{"id":"https://openalex.org/F4320337392","display_name":"Division of Electrical, Communications and Cyber Systems","ror":"https://ror.org/01krpsy48"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1957086046","https://openalex.org/W1963524767","https://openalex.org/W1969689291","https://openalex.org/W1970622583","https://openalex.org/W1974362648","https://openalex.org/W1975713572","https://openalex.org/W1998485893","https://openalex.org/W2027428986","https://openalex.org/W2029581324","https://openalex.org/W2051076903","https://openalex.org/W2095025631","https://openalex.org/W2095376794","https://openalex.org/W2104738142","https://openalex.org/W2110917496","https://openalex.org/W2118661742","https://openalex.org/W2121660527","https://openalex.org/W2124610846","https://openalex.org/W2128089751","https://openalex.org/W2143028346","https://openalex.org/W2155983695","https://openalex.org/W2157194373","https://openalex.org/W2165414990","https://openalex.org/W2167998160","https://openalex.org/W2170271633","https://openalex.org/W2317379906","https://openalex.org/W2318861077","https://openalex.org/W2318861083","https://openalex.org/W2426206508","https://openalex.org/W2570578972","https://openalex.org/W2749633151","https://openalex.org/W2797965694"],"related_works":["https://openalex.org/W2317379906","https://openalex.org/W2920004613","https://openalex.org/W1538632251","https://openalex.org/W4308055961","https://openalex.org/W2117089137","https://openalex.org/W2767166598","https://openalex.org/W2587068425","https://openalex.org/W2165414990","https://openalex.org/W2070661459","https://openalex.org/W3118151523"],"abstract_inverted_index":{"Directing":[0],"neurons":[1,76,203],"to":[2,41,114,118,129,161,191,208],"form":[3],"predetermined":[4],"circuits":[5,195],"with":[6,180],"the":[7,66,108,126,138,142,175,189],"intention":[8],"of":[9,43,53,55,73,93,101,155,184,201],"treating":[10],"neurological":[11],"disorders":[12],"and":[13,20,32,69,112,147,150,179,199,204,215],"neurodegenerative":[14],"diseases":[15],"is":[16],"a":[17,50,120],"fundamental":[18],"goal":[19],"current":[21],"challenge":[22],"in":[23,34,63,65,116,211],"neuroengineering.":[24],"Until":[25],"recently,":[26],"only":[27],"neuronal":[28,67],"aggregates":[29],"were":[30,80,158],"studied":[31],"characterized":[33,111],"culture,":[35],"which":[36],"can":[37,205],"limit":[38],"information":[39],"gathered":[40],"populations":[42],"cells.":[44],"In":[45],"this":[46,185],"study,":[47],"we":[48],"use":[49],"substrate":[51],"constructed":[52],"arrays":[54],"strain-induced":[56],"self-rolled-up":[57],"membrane":[58],"3D":[59],"architectures.":[60],"This":[61],"results":[62],"changes":[64],"architecture":[68],"altered":[70],"growth":[71,106],"dynamics":[72],"neurites.":[74],"Hippocampal":[75],"from":[77],"postnatal":[78],"rats":[79],"cultured":[81],"at":[82],"low":[83],"confluency":[84],"(\u223c250":[85],"cells":[86],"mm":[87],"\u20132":[88],")":[89],"on":[90,107,141,165],"an":[91],"array":[92,156,197],"transparent":[94],"rolled-up":[95],"microtubes":[96],"(\u03bc-tubes;":[97],"4\u20135":[98],"\u03bcm":[99],"diameter)":[100],"varying":[102],"topographical":[103],"arrangements.":[104],"Neurite":[105],"\u03bc-tubes":[109],"was":[110,172],"compared":[113],"controls":[115],"order":[117],"establish":[119],"baseline":[121],"for":[122],"alignment":[123,171],"imposed":[124],"by":[125,174],"topography.":[127],"Compared":[128],"control":[130],"substrates,":[131],"neurites":[132],"are":[133],"significantly":[134],"more":[135],"aligned":[136],"toward":[137],"0\u00b0":[139],"reference":[140],"\u03bc-tube":[143,151],"array.":[144],"Pitch":[145],"(20\u201360":[146],"100":[148],"\u03bcm)":[149,154],"length":[152],"(30\u201380":[153],"elements":[157],"also":[159],"varied":[160],"investigate":[162],"their":[163],"impact":[164],"neurite":[166],"alignment.":[167],"We":[168],"found":[169],"that":[170],"improved":[173],"gradient":[176],"pitch":[177],"arrangement":[178],"longer":[181],"\u03bc-tubes.":[182],"Application":[183],"technology":[186],"will":[187],"enhance":[188],"ability":[190],"construct":[192],"intentional":[193],"neural":[194,212],"through":[196],"design":[198],"manipulation":[200],"individual":[202],"be":[206],"adapted":[207],"address":[209],"challenges":[210],"repair,":[213],"reinnervation,":[214],"neuroregeneration.":[216]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-10-05T00:00:00"}