{"id":"https://openalex.org/W2892353645","doi":"https://doi.org/10.1016/j.bbrc.2018.09.017","title":"Identification and characterization of a novel phosphoregulatory site on cyclin-dependent kinase 5","display_name":"Identification and characterization of a novel phosphoregulatory site on cyclin-dependent kinase 5","publication_year":2018,"publication_date":"2018-09-11","ids":{"openalex":"https://openalex.org/W2892353645","doi":"https://doi.org/10.1016/j.bbrc.2018.09.017","mag":"2892353645","pmid":"https://pubmed.ncbi.nlm.nih.gov/30217452","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6173645"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbrc.2018.09.017","doi":"https://doi.org/10.1016/j.bbrc.2018.09.017","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbrc.2018.09.017","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.bbrc.2018.09.017","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013119443","display_name":"Brett Roach","orcid":"https://orcid.org/0000-0002-4232-5992","observed_orcids":["https://orcid.org/0000-0002-4232-5992"]},"institutions":[{"id":"https://openalex.org/I59897056","display_name":"California State University, Long Beach","ror":"https://ror.org/0080fxk18","country_code":"US","type":"education","lineage":["https://openalex.org/I59897056"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brett Lee Roach","raw_affiliation_strings":["Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States","institution_ids":["https://openalex.org/I59897056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027708822","display_name":"Jordan Matthew Ngo","orcid":"https://orcid.org/0000-0002-6566-3919","observed_orcids":["https://orcid.org/0000-0002-6566-3919"]},"institutions":[{"id":"https://openalex.org/I59897056","display_name":"California State University, Long Beach","ror":"https://ror.org/0080fxk18","country_code":"US","type":"education","lineage":["https://openalex.org/I59897056"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jordan Matthew Ngo","raw_affiliation_strings":["Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States","institution_ids":["https://openalex.org/I59897056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073704993","display_name":"Clariss Limso","orcid":"https://orcid.org/0000-0002-7464-7865","observed_orcids":["https://orcid.org/0000-0002-7464-7865"]},"institutions":[{"id":"https://openalex.org/I59897056","display_name":"California State University, Long Beach","ror":"https://ror.org/0080fxk18","country_code":"US","type":"education","lineage":["https://openalex.org/I59897056"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Clariss Limso","raw_affiliation_strings":["Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States","institution_ids":["https://openalex.org/I59897056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010982034","display_name":"Koyinsola Bolutife Oloja","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59897056","display_name":"California State University, Long Beach","ror":"https://ror.org/0080fxk18","country_code":"US","type":"education","lineage":["https://openalex.org/I59897056"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Koyinsola Bolutife Oloja","raw_affiliation_strings":["Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States","institution_ids":["https://openalex.org/I59897056"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074903754","display_name":"Deepali Bhandari","orcid":"https://orcid.org/0000-0003-1073-7236","observed_orcids":["https://orcid.org/0000-0003-1073-7236"]},"institutions":[{"id":"https://openalex.org/I59897056","display_name":"California State University, Long Beach","ror":"https://ror.org/0080fxk18","country_code":"US","type":"education","lineage":["https://openalex.org/I59897056"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Deepali Bhandari","raw_affiliation_strings":["Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States. Electronic address: deepali.bhandari@csulb.edu","Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States"],"raw_orcid":"https://orcid.org/0000-0003-1073-7236","affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States. Electronic address: deepali.bhandari@csulb.edu","institution_ids":["https://openalex.org/I59897056"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, California State University Long Beach, CA, 90840, United States","institution_ids":["https://openalex.org/I59897056"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5074903754"],"corresponding_institution_ids":["https://openalex.org/I59897056"],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":0.1056,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.49262245,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"504","issue":"4","first_page":"753","last_page":"758"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.7842000126838684,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.7842000126838684,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.16519999504089355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.014100000262260437,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cdk5","display_name":"cyclin-dependent kinase 5","score":0.9990000128746033},{"id":"https://openalex.org/keywords/phosphorylation-sites","display_name":"phosphorylation sites","score":0.6190000176429749},{"id":"https://openalex.org/keywords/p35","display_name":"p35","score":0.8059999942779541},{"id":"https://openalex.org/keywords/kinase-activation","display_name":"kinase activation","score":0.6890000104904175},{"id":"https://openalex.org/keywords/phosphomimetic-mutant","display_name":"phosphomimetic mutant","score":0.7609999775886536},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.6660000085830688},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/kinase-regulation","display_name":"kinase regulation","score":0.6930000185966492}],"concepts":[{"id":"https://openalex.org/C121738310","wikidata":"https://www.wikidata.org/wiki/Q18248262","display_name":"Cyclin-dependent kinase 5","level":5,"score":0.9151361584663391},{"id":"https://openalex.org/C124320809","wikidata":"https://www.wikidata.org/wiki/Q46292","display_name":"Cyclin-dependent kinase","level":4,"score":0.7574882507324219},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.6715126037597656},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.61381995677948},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5912588834762573},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.530346691608429},{"id":"https://openalex.org/C82495950","wikidata":"https://www.wikidata.org/wiki/Q14911732","display_name":"Cyclin-dependent kinase 2","level":4,"score":0.5009229183197021},{"id":"https://openalex.org/C88045685","wikidata":"https://www.wikidata.org/wiki/Q174576","display_name":"Activator (genetics)","level":3,"score":0.4770435690879822},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.4489712119102478},{"id":"https://openalex.org/C51853150","wikidata":"https://www.wikidata.org/wiki/Q14911754","display_name":"Cyclin-dependent kinase 4","level":5,"score":0.4367801547050476},{"id":"https://openalex.org/C124160383","wikidata":"https://www.wikidata.org/wiki/Q14914383","display_name":"ASK1","level":5,"score":0.42096149921417236},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.3326975405216217},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.313655823469162},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.260042667388916},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12842601537704468}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002522","descriptor_name":"Chlorocebus aethiops","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004789","descriptor_name":"Enzyme Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010770","descriptor_name":"Phosphotransferases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019556","descriptor_name":"COS Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051360","descriptor_name":"Cyclin-Dependent Kinase 5","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051360","descriptor_name":"Cyclin-Dependent Kinase 5","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.bbrc.2018.09.017","doi":"https://doi.org/10.1016/j.bbrc.2018.09.017","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbrc.2018.09.017","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},{"id":"pmid:30217452","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30217452","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and biophysical research communications","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6173645","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6173645","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biochem Biophys Res Commun","raw_type":"Text"},{"id":"pmh:oai:pqdtoai.proquest.com:13809913","doi":null,"is_oa":false,"landing_page_url":"http://pqdtopen.proquest.com/#viewpdf?dispub=13809913","pdf_url":"http://pqdtopen.proquest.com/#viewpdf?dispub=13809913","source":{"id":"https://openalex.org/S7407064308","display_name":"ProQuest Demo Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"thesis"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt5778805d","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/5778805d","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biochemical and Biophysical Research Communications, vol 504, iss 4","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.bbrc.2018.09.017","doi":"https://doi.org/10.1016/j.bbrc.2018.09.017","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbrc.2018.09.017","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.428600013256073,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G100202407","display_name":"Building Infrastructure Leading to Diversity (BUILD) Initiative Phase II","funder_award_id":"TL4GM118980","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G1453478190","display_name":"CSULB MARC U*STAR Training Program","funder_award_id":"T34GM008074","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2713908990","display_name":"Novel Insights into Cancer Cell Survival During Endoplasmic Reticulum Stress","funder_award_id":"SC2GM121246","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6130786114","display_name":"Building Infrastructure Leading to Diversity (BUILD) Initiative Phase II","funder_award_id":"RL5GM118978","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6458799643","display_name":"CSULB Research Initiative for Scientific Enhancement 2020-2025","funder_award_id":"R25GM071638","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G693223883","display_name":"Building Infrastructure Leading to Diversity (BUILD) Initiative Phase II","funder_award_id":"UL1GM118979","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332632","display_name":"California State University Long Beach","ror":"https://ror.org/0080fxk18"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1577397450","https://openalex.org/W1955181723","https://openalex.org/W1964830067","https://openalex.org/W1969345506","https://openalex.org/W1969417329","https://openalex.org/W1971103841","https://openalex.org/W1971468364","https://openalex.org/W1977971438","https://openalex.org/W1983097317","https://openalex.org/W1984886327","https://openalex.org/W1990922641","https://openalex.org/W2009204794","https://openalex.org/W2021737325","https://openalex.org/W2033349885","https://openalex.org/W2035542044","https://openalex.org/W2046640720","https://openalex.org/W2052753918","https://openalex.org/W2053160247","https://openalex.org/W2053526638","https://openalex.org/W2066704947","https://openalex.org/W2066888192","https://openalex.org/W2074366990","https://openalex.org/W2076762827","https://openalex.org/W2077642972","https://openalex.org/W2077977333","https://openalex.org/W2078387449","https://openalex.org/W2089353165","https://openalex.org/W2089465156","https://openalex.org/W2118460316","https://openalex.org/W2132503351","https://openalex.org/W2132629607","https://openalex.org/W2156114958","https://openalex.org/W2529684147","https://openalex.org/W2612194469","https://openalex.org/W2762859321","https://openalex.org/W6669041494"],"related_works":["https://openalex.org/W1990922641","https://openalex.org/W2053526638","https://openalex.org/W2129866123","https://openalex.org/W2526232652","https://openalex.org/W3173620010","https://openalex.org/W7212261072","https://openalex.org/W7154104748","https://openalex.org/W2066704947","https://openalex.org/W2151973074","https://openalex.org/W2083927760"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-09-27T00:00:00"}