{"id":"https://openalex.org/W2892339646","doi":"https://doi.org/10.1039/c8tb01885e","title":"A new GFP fluorophore-based probe for lysosome labelling and tracing lysosomal viscosity in live cells","display_name":"A new GFP fluorophore-based probe for lysosome labelling and tracing lysosomal viscosity in live cells","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2892339646","doi":"https://doi.org/10.1039/c8tb01885e","mag":"2892339646","pmid":"https://pubmed.ncbi.nlm.nih.gov/32254867"},"language":"en","primary_location":{"id":"doi:10.1039/c8tb01885e","doi":"https://doi.org/10.1039/c8tb01885e","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c8tb01885e","pdf_url":null,"source":{"id":"https://openalex.org/S2479884170","display_name":"Journal of Materials Chemistry B","issn_l":"2050-750X","issn":["2050-750X","2050-7518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Chemistry B","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Xiaolin Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I21945476","display_name":"Shanghai Normal University","ror":"https://ror.org/01cxqmw89","country_code":"CN","type":"education","lineage":["https://openalex.org/I21945476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaolin Li","raw_affiliation_strings":["Department of Chemistry, Shanghai Normal University","Key Laboratory of Molecular Imaging Probes and Sensors","Shanghai 200234","Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee","The Education Ministry Key Laboratory of Resource Chemistry","The Education Ministry Key Laboratory of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee, Key Laboratory of Molecular Imaging Probes and Sensors, Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Shanghai Normal University","institution_ids":["https://openalex.org/I21945476"]},{"raw_affiliation_string":"Key Laboratory of Molecular Imaging Probes and Sensors","institution_ids":[]},{"raw_affiliation_string":"Shanghai 200234","institution_ids":[]},{"raw_affiliation_string":"Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee","institution_ids":[]},{"raw_affiliation_string":"The Education Ministry Key Laboratory of Resource Chemistry","institution_ids":[]},{"raw_affiliation_string":"The Education Ministry Key Laboratory of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee, Key Laboratory of Molecular Imaging Probes and Sensors, Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, China","institution_ids":["https://openalex.org/I21945476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013656345","display_name":"Rongrong Zhao","orcid":"https://orcid.org/0000-0001-5626-1961","observed_orcids":["https://orcid.org/0000-0001-5626-1961"]},"institutions":[{"id":"https://openalex.org/I21945476","display_name":"Shanghai Normal University","ror":"https://ror.org/01cxqmw89","country_code":"CN","type":"education","lineage":["https://openalex.org/I21945476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rongrong Zhao","raw_affiliation_strings":["Department of Chemistry, Shanghai Normal University","Key Laboratory of Molecular Imaging Probes and Sensors","Shanghai 200234","Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee","The Education Ministry Key Laboratory of Resource Chemistry","The Education Ministry Key Laboratory of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee, Key Laboratory of Molecular Imaging Probes and Sensors, Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Shanghai Normal University","institution_ids":["https://openalex.org/I21945476"]},{"raw_affiliation_string":"Key Laboratory of Molecular Imaging Probes and Sensors","institution_ids":[]},{"raw_affiliation_string":"Shanghai 200234","institution_ids":[]},{"raw_affiliation_string":"Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee","institution_ids":[]},{"raw_affiliation_string":"The Education Ministry Key Laboratory of Resource Chemistry","institution_ids":[]},{"raw_affiliation_string":"The Education Ministry Key Laboratory of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee, Key Laboratory of Molecular Imaging Probes and Sensors, Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, China","institution_ids":["https://openalex.org/I21945476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070580299","display_name":"Yang Wang","orcid":"https://orcid.org/0000-0001-8100-9194","observed_orcids":["https://orcid.org/0000-0001-8100-9194"]},"institutions":[{"id":"https://openalex.org/I21945476","display_name":"Shanghai Normal University","ror":"https://ror.org/01cxqmw89","country_code":"CN","type":"education","lineage":["https://openalex.org/I21945476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Wang","raw_affiliation_strings":["Department of Chemistry, Shanghai Normal University","Key Laboratory of Molecular Imaging Probes and Sensors","Shanghai 200234","Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee","The Education Ministry Key Laboratory of Resource Chemistry","The Education Ministry Key Laboratory of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee, Key Laboratory of Molecular Imaging Probes and Sensors, Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Shanghai Normal University","institution_ids":["https://openalex.org/I21945476"]},{"raw_affiliation_string":"Key Laboratory of Molecular Imaging Probes and Sensors","institution_ids":[]},{"raw_affiliation_string":"Shanghai 200234","institution_ids":[]},{"raw_affiliation_string":"Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee","institution_ids":[]},{"raw_affiliation_string":"The Education Ministry Key Laboratory of Resource Chemistry","institution_ids":[]},{"raw_affiliation_string":"The Education Ministry Key Laboratory of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee, Key Laboratory of Molecular Imaging Probes and Sensors, Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, China","institution_ids":["https://openalex.org/I21945476"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087104609","display_name":"Chusen Huang","orcid":"https://orcid.org/0000-0002-2481-9147","observed_orcids":["https://orcid.org/0000-0002-2481-9147"]},"institutions":[{"id":"https://openalex.org/I21945476","display_name":"Shanghai Normal University","ror":"https://ror.org/01cxqmw89","country_code":"CN","type":"education","lineage":["https://openalex.org/I21945476"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chusen Huang","raw_affiliation_strings":["Department of Chemistry, Shanghai Normal University","Key Laboratory of Molecular Imaging Probes and Sensors","Shanghai 200234","Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee","The Education Ministry Key Laboratory of Resource Chemistry","The Education Ministry Key Laboratory of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee, Key Laboratory of Molecular Imaging Probes and Sensors, Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, China"],"raw_orcid":"https://orcid.org/0000-0002-2481-9147","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Shanghai Normal University","institution_ids":["https://openalex.org/I21945476"]},{"raw_affiliation_string":"Key Laboratory of Molecular Imaging Probes and Sensors","institution_ids":[]},{"raw_affiliation_string":"Shanghai 200234","institution_ids":[]},{"raw_affiliation_string":"Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee","institution_ids":[]},{"raw_affiliation_string":"The Education Ministry Key Laboratory of Resource Chemistry","institution_ids":[]},{"raw_affiliation_string":"The Education Ministry Key Laboratory of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee, Key Laboratory of Molecular Imaging Probes and Sensors, Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, China","institution_ids":["https://openalex.org/I21945476"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5087104609"],"corresponding_institution_ids":["https://openalex.org/I21945476"],"apc_list":null,"apc_paid":null,"fwci":2.4268,"has_fulltext":false,"cited_by_count":78,"citation_normalized_percentile":{"value":0.89931131,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"6","issue":"41","first_page":"6592","last_page":"6598"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.01590000092983246,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11240","display_name":"Luminescence and Fluorescent Materials","score":0.013899999670684338,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluorescent-probes","display_name":"fluorescent probes","score":0.5149999856948853},{"id":"https://openalex.org/keywords/dexamethasone","display_name":"dexamethasone","score":0.8190000057220459},{"id":"https://openalex.org/keywords/live-cell-imaging","display_name":"live-cell imaging","score":0.7279999852180481},{"id":"https://openalex.org/keywords/lysosome-function","display_name":"lysosomal function","score":0.4580000042915344}],"concepts":[{"id":"https://openalex.org/C2780216420","wikidata":"https://www.wikidata.org/wiki/Q83330","display_name":"Lysosome","level":3,"score":0.8316870927810669},{"id":"https://openalex.org/C2778617687","wikidata":"https://www.wikidata.org/wiki/Q2448456","display_name":"Fluorophore","level":3,"score":0.8247063755989075},{"id":"https://openalex.org/C142613039","wikidata":"https://www.wikidata.org/wiki/Q272983","display_name":"Green fluorescent protein","level":3,"score":0.6692808270454407},{"id":"https://openalex.org/C2780523633","wikidata":"https://www.wikidata.org/wiki/Q380709","display_name":"Labelling","level":2,"score":0.6437101364135742},{"id":"https://openalex.org/C138673069","wikidata":"https://www.wikidata.org/wiki/Q322229","display_name":"Tracing","level":2,"score":0.6084874868392944},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.5164311528205872},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.49109888076782227},{"id":"https://openalex.org/C52909226","wikidata":"https://www.wikidata.org/wiki/Q5462835","display_name":"Fluorescent labelling","level":3,"score":0.4675140976905823},{"id":"https://openalex.org/C15526883","wikidata":"https://www.wikidata.org/wiki/Q6657126","display_name":"Live cell imaging","level":3,"score":0.42448094487190247},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3740866184234619},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.37073850631713867},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.26023077964782715},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.18649277091026306},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17224034667015076},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16038185358047485},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.14365562796592712},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.11319705843925476},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.10282057523727417},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.05520448088645935},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1039/c8tb01885e","doi":"https://doi.org/10.1039/c8tb01885e","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c8tb01885e","pdf_url":null,"source":{"id":"https://openalex.org/S2479884170","display_name":"Journal of Materials Chemistry B","issn_l":"2050-750X","issn":["2050-750X","2050-7518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Chemistry B","raw_type":"journal-article"},{"id":"pmid:32254867","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32254867","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of materials chemistry. B","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4596107216","display_name":null,"funder_award_id":"14CG42","funder_id":"https://openalex.org/F4320321881","funder_display_name":"Shanghai Municipal Education Commission"},{"id":"https://openalex.org/G4848688606","display_name":null,"funder_award_id":"14CG42","funder_id":"https://openalex.org/F4320321659","funder_display_name":"Shanghai Education Development Foundation"},{"id":"https://openalex.org/G5739256038","display_name":"\u86cb\u767d\u8d28\u76f8\u90bb\u5def\u57fa\u52a8\u6001\u6210\u50cf\u548c\u5b9a\u91cf\u68c0\u6d4b\u53ca\u5176\u5728\u708e\u75c7\u548c\u80bf\u7624\u5fae\u73af\u5883\u68c0\u6d4b\u5e94\u7528\u7814\u7a76","funder_award_id":"21672150","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5883148678","display_name":null,"funder_award_id":"20133127120005","funder_id":"https://openalex.org/F4320321106","funder_display_name":"Ministry of Education of the People's Republic of China"},{"id":"https://openalex.org/G5895203045","display_name":null,"funder_award_id":"21302125","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320308269","display_name":"Alexander von Humboldt-Stiftung","ror":"https://ror.org/012kf4317"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321106","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934"},{"id":"https://openalex.org/F4320321659","display_name":"Shanghai Education Development Foundation","ror":"https://ror.org/02kq92y46"},{"id":"https://openalex.org/F4320321881","display_name":"Shanghai Municipal Education Commission","ror":"https://ror.org/05tewj457"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W436836339","https://openalex.org/W1886421786","https://openalex.org/W1975692246","https://openalex.org/W1976300583","https://openalex.org/W1981425870","https://openalex.org/W1988067945","https://openalex.org/W2004304181","https://openalex.org/W2017774652","https://openalex.org/W2030239671","https://openalex.org/W2037132030","https://openalex.org/W2042211139","https://openalex.org/W2043002859","https://openalex.org/W2050367299","https://openalex.org/W2058155107","https://openalex.org/W2062499814","https://openalex.org/W2067825015","https://openalex.org/W2073442506","https://openalex.org/W2086654412","https://openalex.org/W2093158675","https://openalex.org/W2096799975","https://openalex.org/W2123282656","https://openalex.org/W2126291337","https://openalex.org/W2161574340","https://openalex.org/W2169908718","https://openalex.org/W2188142157","https://openalex.org/W2259773841","https://openalex.org/W2312635071","https://openalex.org/W2317940519","https://openalex.org/W2325531676","https://openalex.org/W2478638172","https://openalex.org/W2500640366","https://openalex.org/W2506036593","https://openalex.org/W2512484144","https://openalex.org/W2517193673","https://openalex.org/W2522989562","https://openalex.org/W2535359622","https://openalex.org/W2538680875","https://openalex.org/W2560038743","https://openalex.org/W2581946193","https://openalex.org/W2590269775","https://openalex.org/W2597620443","https://openalex.org/W2617178442","https://openalex.org/W2739125283","https://openalex.org/W2754946170","https://openalex.org/W2762095400","https://openalex.org/W2772034630","https://openalex.org/W2777869862","https://openalex.org/W2783402308","https://openalex.org/W2783678270","https://openalex.org/W2794833744","https://openalex.org/W2802103467","https://openalex.org/W2805915372","https://openalex.org/W2807448578","https://openalex.org/W4253179564"],"related_works":["https://openalex.org/W2985594442","https://openalex.org/W1988067945","https://openalex.org/W4389333709","https://openalex.org/W3023050338","https://openalex.org/W3062347070","https://openalex.org/W4283324536","https://openalex.org/W4221029852","https://openalex.org/W4229445920","https://openalex.org/W2794833744","https://openalex.org/W4322580371"],"abstract_inverted_index":{"Lysosomes,":[0],"the":[1,9,16,28,33,42,81,96,133,178,215,235],"main":[2],"digestive":[3],"compartment":[4],"of":[5,32,44,99,123,154,218,237],"live":[6,74,175,209],"cells,":[7],"are":[8],"most":[10],"acidic":[11],"organelles":[12],"(pH":[13],"3.8-6.6)":[14],"with":[15,103],"highest":[17],"viscosity":[18,25,38,72,78,143,180,207],"(47-190":[19],"cP":[20],"at":[21,132],"25":[22],"\u00b0C).":[23],"Lysosomal":[24],"can":[26,79,168],"reflect":[27],"status":[29],"and":[30,35,67,93,106,118,161],"function":[31],"lysosomes,":[34,45],"abnormal":[36],"lysosomal":[37,71,206],"is":[39,47,108,125,139,226],"responsible":[40],"for":[41,69,141,171,204,228],"dysfunction":[43],"which":[46,225],"closely":[48],"related":[49],"to":[50,101,151,198],"multiple":[51],"diseases.":[52],"In":[53],"this":[54],"work,":[55],"a":[56,145,200],"new":[57,201],"GFP":[58],"(green":[59],"fluorescent":[60],"protein)":[61],"fluorophore-based":[62],"probe":[63],"(Lys-V)":[64],"was":[65],"designed":[66],"synthesized":[68],"mapping":[70],"in":[73,128,174,182,208],"cells.":[75,176],"The":[76],"increasing":[77,104],"restrict":[80],"two":[82],"C[double":[83],"bond,":[84],"length":[85],"as":[86,211,213,232,234],"m-dash]C":[87],"twisting":[88],"double":[89],"bonds":[90],"between":[91,113],"phenol":[92],"imidazolidinone,":[94],"causing":[95],"fluorescence":[97,122],"emission":[98],"Lys-V":[100,124,138,167,197],"enhance":[102],"viscosity,":[105,135],"there":[107],"an":[109],"excellent":[110],"linear":[111],"relationship":[112],"log":[114,119],"FI":[115],"(515":[116],"nm)":[117],"viscosity.":[120],"Notably,":[121],"quite":[126],"stable":[127],"different":[129],"pH":[130,147],"solvents":[131],"same":[134],"demonstrating":[136],"that":[137],"suitable":[140],"quantifying":[142],"over":[144],"wide":[146],"range":[148],"(from":[149],"4":[150],"10).":[152],"Because":[153],"its":[155],"ideal":[156],"water":[157],"solubility,":[158],"low":[159],"cytotoxicity":[160],"weak":[162],"basic":[163],"amino":[164],"morpholine":[165],"substituents,":[166],"be":[169,189],"utilized":[170],"lysosome":[172,219],"labelling":[173],"Significantly,":[177],"dynamic":[179],"changes":[181],"lysosomes":[183],"under":[184],"dexamethasone":[185],"stimulus":[186],"could":[187],"also":[188],"captured":[190],"by":[191],"Lys-V.":[192],"Our":[193],"results":[194],"will":[195],"allow":[196],"become":[199],"chemical":[202],"tool":[203],"detecting":[205],"cells":[210],"well":[212,233],"unveiling":[214],"underlying":[216],"mechanism":[217],"behaviour":[220],"during":[221],"various":[222],"biological":[223],"processes,":[224],"beneficial":[227],"studying":[229],"lysosome-related":[230,238],"diseases":[231],"exploration":[236],"pharmacology.":[239]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":18},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-09-27T00:00:00"}