{"id":"https://openalex.org/W2891069702","doi":"https://doi.org/10.1002/slct.201801965","title":"Microwave\u2010Assisted One\u2010Pot Synthesis of New \u03b1 \u2010Aminophosphonates Using ZnBr 2 \u2010SiO 2 as a Catalyst under Solvent\u2010Free Conditions and Their Anticancer Activity","display_name":"Microwave\u2010Assisted One\u2010Pot Synthesis of New \u03b1 \u2010Aminophosphonates Using ZnBr 2 \u2010SiO 2 as a Catalyst under Solvent\u2010Free Conditions and Their Anticancer Activity","publication_year":2018,"publication_date":"2018-09-11","ids":{"openalex":"https://openalex.org/W2891069702","doi":"https://doi.org/10.1002/slct.201801965","mag":"2891069702"},"language":"en","primary_location":{"id":"doi:10.1002/slct.201801965","doi":"https://doi.org/10.1002/slct.201801965","is_oa":false,"landing_page_url":"https://doi.org/10.1002/slct.201801965","pdf_url":null,"source":{"id":"https://openalex.org/S4210221416","display_name":"ChemistrySelect","issn_l":"2365-6549","issn":["2365-6549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemistrySelect","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021866488","display_name":"Geetha Chukka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I221092938","display_name":"Krishna University","ror":"https://ror.org/04yhntq62","country_code":"IN","type":"education","lineage":["https://openalex.org/I221092938"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Geetha Chukka","raw_affiliation_strings":["Department of Chemistry, Krishna University, Machilipatnam, India, 521001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Krishna University, Machilipatnam, India, 521001","institution_ids":["https://openalex.org/I221092938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007705438","display_name":"Muppuru Muni Kesavulu","orcid":"https://orcid.org/0000-0002-3557-4739","observed_orcids":["https://orcid.org/0000-0002-3557-4739"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kesavulu M. Muppuru","raw_affiliation_strings":["Department of Bio-Technology, Sree Vidyanikethan Engineering College, Sree Sainath Nagar, Tirupati, India, 517102"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bio-Technology, Sree Vidyanikethan Engineering College, Sree Sainath Nagar, Tirupati, India, 517102","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042837781","display_name":"Venkanna Banothu","orcid":"https://orcid.org/0000-0002-4446-8786","observed_orcids":["https://orcid.org/0000-0002-4446-8786"]},"institutions":[{"id":"https://openalex.org/I10874241","display_name":"Jawaharlal Nehru Technological University, Hyderabad","ror":"https://ror.org/002tchr49","country_code":"IN","type":"education","lineage":["https://openalex.org/I10874241"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Venkanna Banothu","raw_affiliation_strings":["Centre for Bio-Technology Institute of Science & Technology Jawaharlal Nehru Technological University, Hyderabad India 500085"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Bio-Technology Institute of Science & Technology Jawaharlal Nehru Technological University, Hyderabad India 500085","institution_ids":["https://openalex.org/I10874241"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110855812","display_name":"R. S. BATTU","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Reddy S. Battu","raw_affiliation_strings":["Syn-Finechem Laboratories Private Limited, D-151, Phase III, IDA, Jeedimetla, Hyderabad, India, 50005"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Syn-Finechem Laboratories Private Limited, D-151, Phase III, IDA, Jeedimetla, Hyderabad, India, 50005","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028913716","display_name":"Uma Addepally","orcid":"https://orcid.org/0000-0002-1074-1588","observed_orcids":["https://orcid.org/0000-0002-1074-1588"]},"institutions":[{"id":"https://openalex.org/I10874241","display_name":"Jawaharlal Nehru Technological University, Hyderabad","ror":"https://ror.org/002tchr49","country_code":"IN","type":"education","lineage":["https://openalex.org/I10874241"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Uma Addepally","raw_affiliation_strings":["Centre for Bio-Technology Institute of Science & Technology Jawaharlal Nehru Technological University, Hyderabad India 500085"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Bio-Technology Institute of Science & Technology Jawaharlal Nehru Technological University, Hyderabad India 500085","institution_ids":["https://openalex.org/I10874241"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054528843","display_name":"Syam P. Gandavaram","orcid":"https://orcid.org/0000-0002-1744-3284","observed_orcids":["https://orcid.org/0000-0002-1744-3284"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Syam P. Gandavaram","raw_affiliation_strings":["Department of Chemistry, Sree Vidyanikethan Engineering College, Sree Sainath Nagar, Tirupati, India, 517102"],"raw_orcid":"https://orcid.org/0000-0002-1744-3284","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Sree Vidyanikethan Engineering College, Sree Sainath Nagar, Tirupati, India, 517102","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Naga R. Chamarthi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170558118","display_name":"Sri Venkateswara University","ror":"https://ror.org/05weahn72","country_code":"IN","type":"education","lineage":["https://openalex.org/I170558118"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Naga R. Chamarthi","raw_affiliation_strings":["Department of Chemistry, Sri Venkateswara University, Tirupati, India, 517502"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Sri Venkateswara University, Tirupati, India, 517502","institution_ids":["https://openalex.org/I170558118"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075866533","display_name":"Rao V. B. Mandava","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I221092938","display_name":"Krishna University","ror":"https://ror.org/04yhntq62","country_code":"IN","type":"education","lineage":["https://openalex.org/I221092938"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rao V. B. Mandava","raw_affiliation_strings":["Department of Chemistry, Krishna University, Machilipatnam, India, 521001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Krishna University, Machilipatnam, India, 521001","institution_ids":["https://openalex.org/I221092938"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5054528843"],"corresponding_institution_ids":[],"apc_list":{"value":3880,"currency":"USD","value_usd":3880},"apc_paid":null,"fwci":0.1958,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.31672583,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"3","issue":"34","first_page":"9778","last_page":"9784"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11748","display_name":"Organophosphorus compounds synthesis","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11748","display_name":"Organophosphorus compounds synthesis","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14099","display_name":"Synthesis and Characterization of Heterocyclic Compounds","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12270","display_name":"Microwave-Assisted Synthesis and Applications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpha-aminophosphonates","display_name":"\u03b1-aminophosphonates","score":0.996999979019165},{"id":"https://openalex.org/keywords/kabachnik-fields-reaction","display_name":"Kabachnik-Fields reaction","score":0.9079999923706055},{"id":"https://openalex.org/keywords/three-component-reaction","display_name":"three-component reaction","score":0.7390000224113464},{"id":"https://openalex.org/keywords/microwave-assisted-synthesis","display_name":"microwave-assisted synthesis","score":0.8899999856948853},{"id":"https://openalex.org/keywords/solvent-free-synthesis","display_name":"solvent-free synthesis","score":0.9229999780654907},{"id":"https://openalex.org/keywords/aromatic-aldehydes","display_name":"aromatic aldehydes","score":0.949999988079071},{"id":"https://openalex.org/keywords/diethyl-phosphite","display_name":"diethyl phosphite","score":0.996999979019165},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.9300000071525574},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9940000176429749},{"id":"https://openalex.org/keywords/mda-mb-231-cells","display_name":"MDA-MB-231 cells","score":0.9539999961853027},{"id":"https://openalex.org/keywords/molecular-structure","display_name":"molecular structure","score":0.32199999690055847}],"concepts":[{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.6932275891304016},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6684168577194214},{"id":"https://openalex.org/C2776300020","wikidata":"https://www.wikidata.org/wiki/Q422423","display_name":"Bromide","level":2,"score":0.6089597344398499},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.6045505404472351},{"id":"https://openalex.org/C44838205","wikidata":"https://www.wikidata.org/wiki/Q127995","display_name":"Microwave","level":2,"score":0.4843057692050934},{"id":"https://openalex.org/C535196362","wikidata":"https://www.wikidata.org/wiki/Q758","display_name":"Zinc","level":2,"score":0.4786302149295807},{"id":"https://openalex.org/C2984548686","wikidata":"https://www.wikidata.org/wiki/Q905377","display_name":"Microwave irradiation","level":3,"score":0.4646334946155548},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.43250036239624023},{"id":"https://openalex.org/C2778207378","wikidata":"https://www.wikidata.org/wiki/Q204679","display_name":"Zinc bromide","level":3,"score":0.4223129153251648},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.4067273736000061},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.3659334182739258},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.3449380397796631},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2134568989276886},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/slct.201801965","doi":"https://doi.org/10.1002/slct.201801965","is_oa":false,"landing_page_url":"https://doi.org/10.1002/slct.201801965","pdf_url":null,"source":{"id":"https://openalex.org/S4210221416","display_name":"ChemistrySelect","issn_l":"2365-6549","issn":["2365-6549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemistrySelect","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1992641153","https://openalex.org/W1993805198","https://openalex.org/W1998312816","https://openalex.org/W2000169333","https://openalex.org/W2003917526","https://openalex.org/W2005531486","https://openalex.org/W2021301307","https://openalex.org/W2026598124","https://openalex.org/W2031758700","https://openalex.org/W2059689094","https://openalex.org/W2082703144","https://openalex.org/W2083643936","https://openalex.org/W2086582843","https://openalex.org/W2094498700","https://openalex.org/W2134929738","https://openalex.org/W2177960639","https://openalex.org/W2201710236","https://openalex.org/W2331795712","https://openalex.org/W2378209437","https://openalex.org/W2471954516","https://openalex.org/W2808868559","https://openalex.org/W2951415776","https://openalex.org/W2952261537","https://openalex.org/W2952437848","https://openalex.org/W2952972885"],"related_works":["https://openalex.org/W2471954516","https://openalex.org/W2159421836","https://openalex.org/W1968023361","https://openalex.org/W2324416978","https://openalex.org/W2949356304","https://openalex.org/W2038657030","https://openalex.org/W7099665073","https://openalex.org/W4378438549","https://openalex.org/W2950307585","https://openalex.org/W2972747827"],"abstract_inverted_index":{"Abstract":[0],"Synthesis":[1],"of":[2,5,22,29,79,113,146,155],"a":[3,27,49],"succession":[4],"new":[6,77,144],"\u03b1":[7,130],"\u2010aminophosphonates":[8,131],"4a\u2010j":[9,59],"was":[10],"achieved":[11],"by":[12,18,62],"the":[13,121,141,153],"one\u2010pot":[14],"three\u2010component":[15],"Kabachnik\u2010Fields":[16],"reaction":[17],"reacting":[19],"equimolar":[20],"quantities":[21],"4\u2010morpholinoaniline":[23],"(":[24,36],"1":[25,64],"),":[26],"variety":[28],"aromatic":[30],"aldehydes":[31],"2a\u2010j":[32],"and":[33,71,89],"diethyl":[34],"phosphite":[35],"3":[37],")":[38,47],"using":[39,106],"silica\u2010supported":[40],"zinc":[41],"bromide":[42],"(ZnBr":[43],"2":[44,46],"\u2010SiO":[45],"as":[48],"catalyst":[50],"in":[51,140],"solvent\u2010free":[52],"conditions":[53],"under":[54],"microwave":[55],"(MW)":[56],"irradiation.":[57],"Products":[58],"were":[60],"characterized":[61],"IR,":[63],"H,":[65],"13":[66],"C,":[67],"31":[68],"P,":[69],"NMR":[70],"mass":[72],"spectral":[73],"data.":[74],"For":[75],"these":[76,114],"set":[78],"compounds,":[80],"two\u2010dimensional":[81],"structures":[82],"are":[83,87,104,132],"drawn,":[84],"three\u2010dimensional":[85],"coordinates":[86],"generated":[88],"studied":[90],"for":[91,152],"their":[92],"anti\u2010cancer":[93],"activity":[94,123],"against":[95,124],"breast":[96,107,125],"cancer.":[97,157],"To":[98],"support":[99],"theoretical":[100],"findings,":[101],"experimental":[102],"studies":[103,115],"performed":[105],"cancer":[108,126],"cell":[109],"lines.":[110],"The":[111],"results":[112],"suggested":[116],"that":[117],"analogue,":[118],"4f":[119],"has":[120],"maximum":[122],"cells":[127],"(MDA\u2010MB\u2010231).":[128],"Since":[129],"less":[133],"toxic":[134],"compared":[135],"to":[136],"drugs":[137,147],"currently":[138],"available":[139],"market,":[142],"this":[143],"classes":[145],"have":[148],"very":[149],"good":[150],"potential":[151],"treatment":[154],"Breast":[156]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2018-09-27T00:00:00"}