{"id":"https://openalex.org/W2890625206","doi":"https://doi.org/10.1186/s13148-018-0550-8","title":"Epigenetic regulation of MAGE family in human cancer progression-DNA methylation, histone modification, and non-coding RNAs","display_name":"Epigenetic regulation of MAGE family in human cancer progression-DNA methylation, histone modification, and non-coding RNAs","publication_year":2018,"publication_date":"2018-09-05","ids":{"openalex":"https://openalex.org/W2890625206","doi":"https://doi.org/10.1186/s13148-018-0550-8","mag":"2890625206","pmid":"https://pubmed.ncbi.nlm.nih.gov/30185218","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6126015"},"language":"en","primary_location":{"id":"doi:10.1186/s13148-018-0550-8","doi":"https://doi.org/10.1186/s13148-018-0550-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13148-018-0550-8","pdf_url":"https://clinicalepigeneticsjournal.biomedcentral.com/track/pdf/10.1186/s13148-018-0550-8","source":{"id":"https://openalex.org/S200416800","display_name":"Clinical Epigenetics","issn_l":"1868-7075","issn":["1868-7075","1868-7083"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Epigenetics","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://clinicalepigeneticsjournal.biomedcentral.com/track/pdf/10.1186/s13148-018-0550-8","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068141085","display_name":"Yishui Lian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210106405","display_name":"Fourth Hospital of Hebei Medical University","ror":"https://ror.org/01mdjbm03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yishui Lian","raw_affiliation_strings":["Research Center, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China","institution_ids":["https://openalex.org/I4210106405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072156729","display_name":"Lingjiao Meng","orcid":"https://orcid.org/0000-0001-6730-4154","observed_orcids":["https://orcid.org/0000-0001-6730-4154","https://orcid.org/0000-0001-9316-8774"]},"institutions":[{"id":"https://openalex.org/I4210106405","display_name":"Fourth Hospital of Hebei Medical University","ror":"https://ror.org/01mdjbm03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lingjiao Meng","raw_affiliation_strings":["Research Center, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China","Tumor Research Institute, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China","institution_ids":["https://openalex.org/I4210106405"]},{"raw_affiliation_string":"Tumor Research Institute, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China","institution_ids":["https://openalex.org/I4210106405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006333779","display_name":"Ping\u2019an Ding","orcid":"https://orcid.org/0000-0002-8163-0711","observed_orcids":["https://orcid.org/0000-0002-8163-0711"]},"institutions":[{"id":"https://openalex.org/I4210106405","display_name":"Fourth Hospital of Hebei Medical University","ror":"https://ror.org/01mdjbm03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pingan Ding","raw_affiliation_strings":["Research Center, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China","institution_ids":["https://openalex.org/I4210106405"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062925533","display_name":"Meixiang Sang","orcid":"https://orcid.org/0000-0001-8295-8463","observed_orcids":["https://orcid.org/0000-0001-8295-8463"]},"institutions":[{"id":"https://openalex.org/I4210106405","display_name":"Fourth Hospital of Hebei Medical University","ror":"https://ror.org/01mdjbm03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106405"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Meixiang Sang","raw_affiliation_strings":["Research Center, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China. mxsang@hotmail.com","Tumor Research Institute, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China. mxsang@hotmail.com","Tumor Research Institute, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People\u2019s Republic of China"],"raw_orcid":"https://orcid.org/0000-0001-8295-8463","affiliations":[{"raw_affiliation_string":"Research Center, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China. mxsang@hotmail.com","institution_ids":["https://openalex.org/I4210106405"]},{"raw_affiliation_string":"Tumor Research Institute, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People's Republic of China. mxsang@hotmail.com","institution_ids":["https://openalex.org/I4210106405"]},{"raw_affiliation_string":"Tumor Research Institute, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050017, Hebei, People\u2019s Republic of China","institution_ids":["https://openalex.org/I4210106405"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5062925533"],"corresponding_institution_ids":["https://openalex.org/I4210106405"],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":{"value":3890,"currency":"USD","value_usd":3890},"fwci":0.6626,"has_fulltext":true,"cited_by_count":78,"citation_normalized_percentile":{"value":0.56176438,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"10","issue":"1","first_page":"115","last_page":"115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.011699999682605267,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mage-family","display_name":"MAGE family","score":0.8600000143051147},{"id":"https://openalex.org/keywords/cancer-testis-antigens","display_name":"cancer-testis antigens","score":0.9229999780654907},{"id":"https://openalex.org/keywords/epigenetic-regulation","display_name":"epigenetic regulation","score":0.9639999866485596},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.9850000143051147},{"id":"https://openalex.org/keywords/histone-modifications","display_name":"histone modifications","score":0.9919999837875366},{"id":"https://openalex.org/keywords/non-coding-rna","display_name":"non-coding RNA","score":0.9919999837875366},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.9670000076293945},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.8740000128746033},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.6019999980926514}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.843552827835083},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.7260023951530457},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6815280914306641},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.5650266408920288},{"id":"https://openalex.org/C47042493","wikidata":"https://www.wikidata.org/wiki/Q265799","display_name":"Human genetics","level":3,"score":0.5378860831260681},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4844532012939453},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4517504572868347},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4383939802646637},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4370635747909546},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.43053847551345825},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.36105602979660034},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3366308808326721}],"mesh":[{"descriptor_ui":"D000951","descriptor_name":"Antigens, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D042421","descriptor_name":"Histone Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/s13148-018-0550-8","doi":"https://doi.org/10.1186/s13148-018-0550-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13148-018-0550-8","pdf_url":"https://clinicalepigeneticsjournal.biomedcentral.com/track/pdf/10.1186/s13148-018-0550-8","source":{"id":"https://openalex.org/S200416800","display_name":"Clinical Epigenetics","issn_l":"1868-7075","issn":["1868-7075","1868-7083"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Epigenetics","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5081144","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6126015","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6126015","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6126015","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Epigenetics","raw_type":"Text"},{"id":"pmid:30185218","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30185218","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical epigenetics","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:2dd130e499214752a191981e14b3d0c6","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/2dd130e499214752a191981e14b3d0c6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinical Epigenetics, Vol 10, Iss 1, Pp 1-11 (2018)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s13148-018-0550-8","doi":"https://doi.org/10.1186/s13148-018-0550-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13148-018-0550-8","pdf_url":"https://clinicalepigeneticsjournal.biomedcentral.com/track/pdf/10.1186/s13148-018-0550-8","source":{"id":"https://openalex.org/S200416800","display_name":"Clinical Epigenetics","issn_l":"1868-7075","issn":["1868-7075","1868-7083"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Epigenetics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322449","display_name":"Tongji University","ror":"https://ror.org/03rc6as71"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2890625206.pdf","grobid_xml":"https://content.openalex.org/works/W2890625206.grobid-xml"},"referenced_works_count":95,"referenced_works":["https://openalex.org/W106787451","https://openalex.org/W1579417540","https://openalex.org/W1589850088","https://openalex.org/W1909138317","https://openalex.org/W1966498224","https://openalex.org/W1967199837","https://openalex.org/W1970430170","https://openalex.org/W1972989638","https://openalex.org/W1974352623","https://openalex.org/W1974885520","https://openalex.org/W1975437957","https://openalex.org/W1975522366","https://openalex.org/W1976626368","https://openalex.org/W1977927411","https://openalex.org/W1980260817","https://openalex.org/W1984519260","https://openalex.org/W1984622518","https://openalex.org/W1985594917","https://openalex.org/W1986246989","https://openalex.org/W1986627314","https://openalex.org/W1986889426","https://openalex.org/W1988031203","https://openalex.org/W1993267239","https://openalex.org/W2006987944","https://openalex.org/W2021803200","https://openalex.org/W2021841122","https://openalex.org/W2028627769","https://openalex.org/W2029799334","https://openalex.org/W2036106594","https://openalex.org/W2036708294","https://openalex.org/W2040469329","https://openalex.org/W2041013384","https://openalex.org/W2046387002","https://openalex.org/W2050701744","https://openalex.org/W2057586248","https://openalex.org/W2061111901","https://openalex.org/W2062637509","https://openalex.org/W2064165694","https://openalex.org/W2067592017","https://openalex.org/W2075470465","https://openalex.org/W2077085480","https://openalex.org/W2077562677","https://openalex.org/W2087355433","https://openalex.org/W2088911122","https://openalex.org/W2090257623","https://openalex.org/W2095803877","https://openalex.org/W2098646008","https://openalex.org/W2099629753","https://openalex.org/W2099936062","https://openalex.org/W2101659058","https://openalex.org/W2103177465","https://openalex.org/W2107749421","https://openalex.org/W2109197941","https://openalex.org/W2110913360","https://openalex.org/W2116646376","https://openalex.org/W2117391818","https://openalex.org/W2118995187","https://openalex.org/W2121077625","https://openalex.org/W2123964647","https://openalex.org/W2124376559","https://openalex.org/W2127860223","https://openalex.org/W2129664277","https://openalex.org/W2135908778","https://openalex.org/W2139401049","https://openalex.org/W2141738919","https://openalex.org/W2146541911","https://openalex.org/W2148253564","https://openalex.org/W2150741140","https://openalex.org/W2151026121","https://openalex.org/W2151399556","https://openalex.org/W2153952062","https://openalex.org/W2157352980","https://openalex.org/W2157361815","https://openalex.org/W2160164594","https://openalex.org/W2161235568","https://openalex.org/W2164065953","https://openalex.org/W2167855391","https://openalex.org/W2169880521","https://openalex.org/W2177862950","https://openalex.org/W2284100402","https://openalex.org/W2297303969","https://openalex.org/W2326195424","https://openalex.org/W2328653670","https://openalex.org/W2469774961","https://openalex.org/W2471934747","https://openalex.org/W2517720641","https://openalex.org/W2530065162","https://openalex.org/W2533994927","https://openalex.org/W2556540423","https://openalex.org/W2585515863","https://openalex.org/W2592245646","https://openalex.org/W2607272609","https://openalex.org/W2772596501","https://openalex.org/W2795917293","https://openalex.org/W4230705206"],"related_works":["https://openalex.org/W3176229384","https://openalex.org/W3166349494","https://openalex.org/W7100924592","https://openalex.org/W7217851172","https://openalex.org/W1977927411","https://openalex.org/W3019728219","https://openalex.org/W1965915146","https://openalex.org/W2945874663","https://openalex.org/W3206638628","https://openalex.org/W4400519759"],"abstract_inverted_index":{"The":[0],"melanoma":[1],"antigen":[2],"gene":[3],"(MAGE)":[4],"proteins":[5],"are":[6,24],"a":[7,16],"group":[8],"of":[9,67,80,84],"highly":[10],"conserved":[11],"family":[12,69,86],"members":[13],"that":[14,62],"contain":[15],"common":[17],"MAGE":[18,68,85],"homology":[19],"domain.":[20],"Type":[21],"I":[22],"MAGEs":[23],"relevant":[25],"cancer-testis":[26],"antigens":[27],"(CTAs),":[28],"and":[29,60],"originally":[30],"considered":[31],"as":[32],"attractive":[33],"targets":[34],"for":[35],"cancer":[36,71],"immunotherapy":[37],"due":[38],"to":[39],"their":[40],"typically":[41],"high":[42],"expression":[43,49,87],"in":[44,50,70,88],"tumor":[45],"tissues":[46],"but":[47],"restricted":[48],"normal":[51],"adult":[52],"tissues.":[53],"Here,":[54],"we":[55,74],"reviewed":[56],"the":[57,64,77,81],"recent":[58],"discoveries":[59],"ideas":[61],"illustrate":[63],"biological":[65],"functions":[66],"progression.":[72],"Furthermore,":[73],"also":[75],"highlighted":[76],"current":[78],"understanding":[79],"epigenetic":[82],"mechanism":[83],"human":[89],"cancers.":[90]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2018-09-27T00:00:00"}