{"id":"https://openalex.org/W2889927409","doi":"https://doi.org/10.1200/jco.2016.34.15_suppl.e18281","title":"Enabling a paradigm shift: A preference-tolerant RCT of personalized vs. annual screening for breast cancer.","display_name":"Enabling a paradigm shift: A preference-tolerant RCT of personalized vs. annual screening for breast cancer.","publication_year":2016,"publication_date":"2016-05-20","ids":{"openalex":"https://openalex.org/W2889927409","doi":"https://doi.org/10.1200/jco.2016.34.15_suppl.e18281","mag":"2889927409"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2016.34.15_suppl.e18281","doi":"https://doi.org/10.1200/jco.2016.34.15_suppl.e18281","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2016.34.15_suppl.e18281","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068351424","display_name":"Sarah Rosenberg-Wohl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah Rosenberg-Wohl","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA;","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023452331","display_name":"Prihatha R. Narasimmaraj","orcid":"https://orcid.org/0009-0002-3776-2415","observed_orcids":["https://orcid.org/0009-0002-3776-2415"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prihatha Narasimmaraj","raw_affiliation_strings":["University of California, San Francisco, SAN Francisco, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, SAN Francisco, CA;","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087628748","display_name":"Allison Stover Fiscalini","orcid":"https://orcid.org/0000-0002-9639-4053","observed_orcids":["https://orcid.org/0000-0002-9639-4053"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allison S Fiscalini","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA;","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042940359","display_name":"Karyn DiGiorgio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387154595","display_name":"University of California Office of the President","ror":"https://ror.org/00dmfq477","country_code":"US","type":"education","lineage":["https://openalex.org/I4387154595"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karyn DiGiorgio","raw_affiliation_strings":["University of California Office of the President, Oakland, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Office of the President, Oakland, CA;","institution_ids":["https://openalex.org/I4387154595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074514000","display_name":"Lisa Latts","orcid":"https://orcid.org/0000-0001-5133-0008","observed_orcids":["https://orcid.org/0000-0001-5133-0008"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lisa Latts","raw_affiliation_strings":["LML Health Solutions, Denver, CO;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LML Health Solutions, Denver, CO;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080468377","display_name":"Marcus Thygeson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210154906","display_name":"Blue Shield of California Foundation","ror":"https://ror.org/04h97jj05","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210154906"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marcus Thygeson","raw_affiliation_strings":["Blue Shield of California, Chico, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blue Shield of California, Chico, CA;","institution_ids":["https://openalex.org/I4210154906"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073429275","display_name":"Martin Eklund","orcid":"https://orcid.org/0000-0001-5032-5266","observed_orcids":["https://orcid.org/0000-0001-5032-5266"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Martin Eklund","raw_affiliation_strings":["Karolinska Institutet, Department of Medical Epidemiology and Biostatistics (MEB), Stockholm, Sweden;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Department of Medical Epidemiology and Biostatistics (MEB), Stockholm, Sweden;","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110010871","display_name":"Jason Connor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405267949","display_name":"Berry Consultants, LLC (United States)","ror":"https://ror.org/054btrt70","country_code":"US","type":"company","lineage":["https://openalex.org/I4405267949"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason Connor","raw_affiliation_strings":["Berry Consultants, LLC, Austin, TX;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berry Consultants, LLC, Austin, TX;","institution_ids":["https://openalex.org/I4405267949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068491553","display_name":"Kristine R. Broglio","orcid":"https://orcid.org/0000-0002-8405-3702","observed_orcids":["https://orcid.org/0000-0002-8405-3702"]},"institutions":[{"id":"https://openalex.org/I4405267949","display_name":"Berry Consultants, LLC (United States)","ror":"https://ror.org/054btrt70","country_code":"US","type":"company","lineage":["https://openalex.org/I4405267949"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kristine Broglio","raw_affiliation_strings":["Berry Consultants, LLC, Austin, TX;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Berry Consultants, LLC, Austin, TX;","institution_ids":["https://openalex.org/I4405267949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018381415","display_name":"Jeffrey A. Tice","orcid":"https://orcid.org/0000-0002-9857-2028","observed_orcids":["https://orcid.org/0000-0002-9857-2028"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey Tice","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA;","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056443389","display_name":"MaryBeth Kramer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161447","display_name":"Intuitive Surgical (United States)","ror":"https://ror.org/05g2n4m79","country_code":"US","type":"company","lineage":["https://openalex.org/I4210161447"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"MaryBeth Kramer","raw_affiliation_strings":["Intuitive Surgical, Sunnyvale, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Intuitive Surgical, Sunnyvale, CA;","institution_ids":["https://openalex.org/I4210161447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076423165","display_name":"Andrea Z. LaCroix","orcid":"https://orcid.org/0000-0002-9532-976X","observed_orcids":["https://orcid.org/0000-0002-9532-976X","https://orcid.org/0000-0003-0225-2749"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrea LaCroix","raw_affiliation_strings":["University of California, San Diego, La Jolla, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Diego, La Jolla, CA;","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019467370","display_name":"Robert A. Hiatt","orcid":"https://orcid.org/0000-0001-7174-8436","observed_orcids":["https://orcid.org/0000-0001-7174-8436"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert A. Hiatt","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA;","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052399630","display_name":"Barbara A. Parker","orcid":"https://orcid.org/0000-0003-0499-1289","observed_orcids":["https://orcid.org/0000-0003-0499-1289"]},"institutions":[{"id":"https://openalex.org/I4390039236","display_name":"Moores Cancer Center","ror":"https://ror.org/01qkmtm61","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800935791","https://openalex.org/I36258959","https://openalex.org/I4390039236"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Barbara A. Parker","raw_affiliation_strings":["UC San Diego Moores Cancer Center, La Jolla, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC San Diego Moores Cancer Center, La Jolla, CA;","institution_ids":["https://openalex.org/I4390039236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046593827","display_name":"Tracy M. Layton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4390039236","display_name":"Moores Cancer Center","ror":"https://ror.org/01qkmtm61","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800935791","https://openalex.org/I36258959","https://openalex.org/I4390039236"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tracy M. Layton","raw_affiliation_strings":["University of California, San Diego, Moores Cancer Center, La Jolla, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Diego, Moores Cancer Center, La Jolla, CA;","institution_ids":["https://openalex.org/I36258959","https://openalex.org/I4390039236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072789687","display_name":"Laura J. Esserman","orcid":"https://orcid.org/0000-0001-9202-4568","observed_orcids":["https://orcid.org/0000-0001-9202-4568"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura Esserman","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA;","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":null,"display_name":"Athena Breast Health Network","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Athena Breast Health Network","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"34","issue":"15_suppl","first_page":"e18281","last_page":"e18281"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11361","display_name":"Digital Radiography and Breast Imaging","score":0.6484000086784363,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11361","display_name":"Digital Radiography and Breast Imaging","score":0.6484000086784363,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening","score":0.3411000072956085,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13544","display_name":"Women's cancer prevention and management","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer-screening","display_name":"breast cancer screening","score":0.9909999966621399},{"id":"https://openalex.org/keywords/risk-based-screening","display_name":"risk-based screening","score":0.9430000185966492},{"id":"https://openalex.org/keywords/annual-mammography","display_name":"annual mammography","score":0.9319999814033508},{"id":"https://openalex.org/keywords/personalized-screening","display_name":"personalized screening","score":0.6769999861717224},{"id":"https://openalex.org/keywords/uspstf-recommendations","display_name":"USPSTF recommendations","score":0.6650000214576721},{"id":"https://openalex.org/keywords/breast-density","display_name":"breast density","score":0.7170000076293945},{"id":"https://openalex.org/keywords/genetic-risk-factors","display_name":"genetic risk factors","score":0.796999990940094},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.828000009059906},{"id":"https://openalex.org/keywords/patient-centered-outcomes","display_name":"patient-centered outcomes","score":0.5400000214576721},{"id":"https://openalex.org/keywords/coverage-with-evidence-development","display_name":"coverage with evidence development","score":0.7799999713897705},{"id":"https://openalex.org/keywords/stakeholder-engagement","display_name":"stakeholder engagement","score":0.6240000128746033}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8042486310005188},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.5644633173942566},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5529018640518188},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5372808575630188},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5244308114051819},{"id":"https://openalex.org/C2779703844","wikidata":"https://www.wikidata.org/wiki/Q760125","display_name":"Reimbursement","level":3,"score":0.5166723728179932},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.47622376680374146},{"id":"https://openalex.org/C2778111679","wikidata":"https://www.wikidata.org/wiki/Q5155639","display_name":"Comparative effectiveness research","level":3,"score":0.4296048879623413},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.41639429330825806},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.34830543398857117},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29357218742370605},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.20051762461662292},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.1620732545852661},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12432050704956055},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2016.34.15_suppl.e18281","doi":"https://doi.org/10.1200/jco.2016.34.15_suppl.e18281","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2016.34.15_suppl.e18281","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2406119519","https://openalex.org/W2731231674","https://openalex.org/W2790752021","https://openalex.org/W2672672214","https://openalex.org/W2753454143","https://openalex.org/W7129520765","https://openalex.org/W4250846754","https://openalex.org/W3005721688","https://openalex.org/W4414830482","https://openalex.org/W4417304321"],"abstract_inverted_index":{"e18281":[0],"Background:":[1],"For":[2],"almost":[3],"30":[4],"years,":[5,137],"annual":[6,58,98,171],"mammography":[7],"starting":[8],"at":[9],"age":[10],"40":[11],"has":[12,152,217],"been":[13],"a":[14,32,66],"cornerstone":[15],"of":[16,55,242,285,318,323],"the":[17,116,127,168,175,215,227,260,283,286,300,311],"US":[18],"strategy":[19],"to":[20,37,50,92,97,123,132,164,167,199,221,246,255,282],"reduce":[21],"breast":[22],"cancer":[23],"mortality.":[24],"The":[25,45,89,150],"2009":[26],"USPSTF":[27],"screening":[28,59,62],"guidelines,":[29],"despite":[30],"having":[31],"sound":[33],"evidence":[34],"base,":[35],"continue":[36],"spark":[38],"debate.":[39],"Scientific":[40],"opinion":[41],"remains":[42],"divided.":[43],"Methods:":[44],"Wisdom":[46,128],"Study":[47,129],"(Women":[48],"Informed":[49],"Screen":[51],"Depending":[52],"on":[53],"Measures":[54],"Risk)":[56],"compares":[57],"vs.":[60],"risk-based":[61,169],"(RBS).":[63],"In":[64],"RBS,":[65,95],"comprehensive":[67],"risk":[68,72],"model":[69],"incorporates":[70],"high-impact":[71],"factors,":[73],"including":[74,269],"genetic":[75,79],"mutations":[76],"and":[77,87,108,178,187,196,263,277,292],"common":[78],"variants":[80],"(SNPs),":[81],"mammographic":[82],"density,":[83],"family":[84],"history,":[85],"exposures,":[86],"co-morbidities.":[88],"goal":[90],"is":[91,100,103,109,130,197,233,315],"determine":[93,133,247],"if":[94,248,310],"compared":[96],"screening,":[99],"as":[101],"safe,":[102],"less":[104],"morbid,":[105],"enables":[106],"prevention,":[107],"preferred":[110],"by":[111,115],"women.":[112],"Results:":[113],"Funded":[114],"new":[117],"PCORI":[118,208],"initiative":[119],"\u2018Pragmatic":[120],"Clinical":[121,326],"Studies":[122],"Evaluate":[124],"Patient-Centered":[125],"Outcomes\u2019,":[126],"designed":[131],"safety":[134],"in":[135,148,157,201],"5":[136],"demonstrating":[138],"that":[139],"Stage":[140],"IIB":[141],"or":[142,170],"higher":[143],"cancers":[144],"are":[145,161],"not":[146,162,211],"increased":[147],"RBS.":[149],"study":[151,216,261],"an":[153],"innovative":[154],"preference-tolerant":[155],"design":[156],"which":[158],"participants":[159],"who":[160],"willing":[163],"be":[165,251],"randomized":[166],"arm":[172],"may":[173],"join":[174],"observational":[176],"cohort":[177],"choose":[179],"their":[180],"arm,":[181],"thus":[182],"allowing":[183],"for":[184,231,297,302,313],"greater":[185],"representation":[186],"more":[188],"widely":[189],"applicable":[190],"findings.":[191],"RBS":[192,319],"requires":[193],"payor":[194],"engagement":[195],"expected":[198],"result":[200],"cost":[202],"savings":[203],"within":[204],"five":[205],"years.":[206],"Since":[207],"funds":[209],"do":[210],"cover":[212,222,307],"clinical":[213,223,244],"services,":[214,308],"partnered":[218],"with":[219,226,235,266],"insurers":[220],"services":[224],"associated":[225],"trial.":[228],"One":[229],"mechanism":[230],"reimbursement":[232],"Coverage":[234],"Evidence":[236],"Development":[237],"(CED).":[238],"CED":[239],"accelerates":[240],"evaluation":[241],"value-enhancing":[243],"innovations":[245],"they":[249],"should":[250],"made":[252],"permanently":[253],"available":[254],"members.":[256],"Conclusions:":[257],"By":[258],"design,":[259],"engages":[262],"shares":[264],"data":[265],"multiple":[267],"stakeholders":[268,289],"participants,":[270],"investigators,":[271],"policy":[272],"makers,":[273],"technology":[274],"partners,":[275],"payors,":[276],"scientific":[278],"granting":[279],"agencies.":[280],"Prior":[281],"launch":[284],"study,":[287],"all":[288],"agree":[290],"upon,":[291],"have":[293],"access":[294],"to,":[295],"metrics":[296],"what":[298],"constitutes":[299],"threshold":[301,312],"adoption.":[303],"Payors":[304],"will":[305],"already":[306],"so":[309],"adoption":[314],"reached,":[316],"implementation":[317],"can":[320],"become":[321],"standard":[322],"care":[324],"immediately.":[325],"trial":[327],"information:":[328],"NCT02620852.":[329]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2018-09-27T00:00:00"}