{"id":"https://openalex.org/W2888616101","doi":"https://doi.org/10.1101/cshperspect.a034231","title":"Bioelectronic Approaches to Control Neuroimmune Interactions in Acute Kidney Injury","display_name":"Bioelectronic Approaches to Control Neuroimmune Interactions in Acute Kidney Injury","publication_year":2018,"publication_date":"2018-08-20","ids":{"openalex":"https://openalex.org/W2888616101","doi":"https://doi.org/10.1101/cshperspect.a034231","mag":"2888616101","pmid":"https://pubmed.ncbi.nlm.nih.gov/30126836","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6546041"},"language":"en","primary_location":{"id":"doi:10.1101/cshperspect.a034231","doi":"https://doi.org/10.1101/cshperspect.a034231","is_oa":true,"landing_page_url":"https://doi.org/10.1101/cshperspect.a034231","pdf_url":"http://perspectivesinmedicine.cshlp.org/content/9/6/a034231.full.pdf","source":{"id":"https://openalex.org/S2479837110","display_name":"Cold Spring Harbor Perspectives in Medicine","issn_l":"2157-1422","issn":["2157-1422","2472-5412"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor Perspectives in Medicine","raw_type":"journal-article"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://perspectivesinmedicine.cshlp.org/content/9/6/a034231.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073245835","display_name":"Tsuyoshi Inoue","orcid":"https://orcid.org/0000-0003-2208-7584","observed_orcids":["https://orcid.org/0000-0003-2208-7584"]},"institutions":[{"id":"https://openalex.org/I2799765794","display_name":"University of Virginia Health System","ror":"https://ror.org/00wn7d965","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799765794"]},{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tsuyoshi Inoue","raw_affiliation_strings":["Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908","1Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908","institution_ids":["https://openalex.org/I2799765794","https://openalex.org/I51556381"]},{"raw_affiliation_string":"1Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908","institution_ids":["https://openalex.org/I2799765794","https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033251045","display_name":"Shinji Tanaka","orcid":"https://orcid.org/0000-0003-3906-6675","observed_orcids":["https://orcid.org/0000-0003-3906-6675"]},"institutions":[{"id":"https://openalex.org/I2799765794","display_name":"University of Virginia Health System","ror":"https://ror.org/00wn7d965","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799765794"]},{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shinji Tanaka","raw_affiliation_strings":["Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908","1Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908","institution_ids":["https://openalex.org/I2799765794","https://openalex.org/I51556381"]},{"raw_affiliation_string":"1Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908","institution_ids":["https://openalex.org/I2799765794","https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017888514","display_name":"Diane L. Rosin","orcid":"https://orcid.org/0000-0003-0187-5717","observed_orcids":["https://orcid.org/0000-0003-0187-5717"]},"institutions":[{"id":"https://openalex.org/I2799765794","display_name":"University of Virginia Health System","ror":"https://ror.org/00wn7d965","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799765794"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diane L. Rosin","raw_affiliation_strings":["Department of Pharmacology, University of Virginia Health System Charlottesville, Virginia 22908","2Department of Pharmacology, University of Virginia Health System Charlottesville, Virginia 22908"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Virginia Health System Charlottesville, Virginia 22908","institution_ids":["https://openalex.org/I2799765794"]},{"raw_affiliation_string":"2Department of Pharmacology, University of Virginia Health System Charlottesville, Virginia 22908","institution_ids":["https://openalex.org/I2799765794"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043847672","display_name":"Mark Douglas Okusa","orcid":"https://orcid.org/0000-0002-0801-0532","observed_orcids":["https://orcid.org/0000-0002-0801-0532"]},"institutions":[{"id":"https://openalex.org/I2799765794","display_name":"University of Virginia Health System","ror":"https://ror.org/00wn7d965","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799765794"]},{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark D. Okusa","raw_affiliation_strings":["Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908","1Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908","institution_ids":["https://openalex.org/I2799765794","https://openalex.org/I51556381"]},{"raw_affiliation_string":"1Division of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia Health System, Charlottesville, Virginia 22908","institution_ids":["https://openalex.org/I2799765794","https://openalex.org/I51556381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"6","first_page":"a034231","last_page":"a034231"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12580","display_name":"Vagus Nerve Stimulation Research","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12580","display_name":"Vagus Nerve Stimulation Research","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.034699998795986176,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-kidney-injury","display_name":"acute kidney injury","score":0.9459999799728394},{"id":"https://openalex.org/keywords/bioelectronic-medicine","display_name":"bioelectronic medicine","score":0.7369999885559082},{"id":"https://openalex.org/keywords/neuroimmune-interactions","display_name":"neuroimmune interactions","score":0.9089999794960022},{"id":"https://openalex.org/keywords/cholinergic-anti-inflammatory-pathway","display_name":"cholinergic anti-inflammatory pathway","score":0.9779999852180481},{"id":"https://openalex.org/keywords/vagus-nerve-stimulation","display_name":"vagus nerve stimulation","score":0.8320000171661377},{"id":"https://openalex.org/keywords/optogenetics","display_name":"optogenetics","score":0.7120000123977661},{"id":"https://openalex.org/keywords/therapeutic-ultrasound","display_name":"ultrasound therapy","score":0.5830000042915344},{"id":"https://openalex.org/keywords/nicotinic-acetylcholine-receptors","display_name":"nicotinic acetylcholine receptors","score":0.9179999828338623},{"id":"https://openalex.org/keywords/alpha7-nicotinic-acetylcholine-receptor","display_name":"alpha7 nicotinic acetylcholine receptor","score":0.7379999756813049},{"id":"https://openalex.org/keywords/beta2-adrenergic-receptor","display_name":"beta2-adrenergic receptor","score":0.9769999980926514},{"id":"https://openalex.org/keywords/renal-protection","display_name":"renal protection","score":0.8009999990463257},{"id":"https://openalex.org/keywords/splenectomy","display_name":"splenectomy","score":0.7279999852180481}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5360145568847656},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5211829543113708},{"id":"https://openalex.org/C2780472472","wikidata":"https://www.wikidata.org/wiki/Q424337","display_name":"Acute kidney injury","level":2,"score":0.4710680842399597},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.23045504093170166},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19164597988128662}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001341","descriptor_name":"Autonomic Nervous System","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001341","descriptor_name":"Autonomic Nervous System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014630","descriptor_name":"Vagus Nerve","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014630","descriptor_name":"Vagus Nerve","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D015213","descriptor_name":"Neuroimmunomodulation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1101/cshperspect.a034231","doi":"https://doi.org/10.1101/cshperspect.a034231","is_oa":true,"landing_page_url":"https://doi.org/10.1101/cshperspect.a034231","pdf_url":"http://perspectivesinmedicine.cshlp.org/content/9/6/a034231.full.pdf","source":{"id":"https://openalex.org/S2479837110","display_name":"Cold Spring Harbor Perspectives in Medicine","issn_l":"2157-1422","issn":["2157-1422","2472-5412"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor Perspectives in Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6546041","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6546041","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harb Perspect Med","raw_type":"Text"},{"id":"pmid:30126836","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30126836","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor perspectives in medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1101/cshperspect.a034231","doi":"https://doi.org/10.1101/cshperspect.a034231","is_oa":true,"landing_page_url":"https://doi.org/10.1101/cshperspect.a034231","pdf_url":"http://perspectivesinmedicine.cshlp.org/content/9/6/a034231.full.pdf","source":{"id":"https://openalex.org/S2479837110","display_name":"Cold Spring Harbor Perspectives in Medicine","issn_l":"2157-1422","issn":["2157-1422","2472-5412"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor Perspectives in Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9907000064849854}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3026615696","display_name":"Leukocyte trafficking in acute renal failure","funder_award_id":"R01DK062324","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3306864319","display_name":"Elucidation of immune cell activation mechanism in the cholinergic anti-inflammatory pathway","funder_award_id":"19K21297","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6895209274","display_name":"Sphingolipids in Acute Kidney Injury and Disease Progression","funder_award_id":"R01DK085259","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2888616101.pdf","grobid_xml":"https://content.openalex.org/works/W2888616101.grobid-xml"},"referenced_works_count":89,"referenced_works":["https://openalex.org/W953222022","https://openalex.org/W1489794536","https://openalex.org/W1814430977","https://openalex.org/W1964536962","https://openalex.org/W1965675690","https://openalex.org/W1968982398","https://openalex.org/W1970911736","https://openalex.org/W1976776656","https://openalex.org/W1986240011","https://openalex.org/W1989448739","https://openalex.org/W1990488806","https://openalex.org/W1995525413","https://openalex.org/W1996020381","https://openalex.org/W2002797282","https://openalex.org/W2007041596","https://openalex.org/W2007143131","https://openalex.org/W2015262831","https://openalex.org/W2016318035","https://openalex.org/W2022782996","https://openalex.org/W2027337530","https://openalex.org/W2031786722","https://openalex.org/W2033169788","https://openalex.org/W2035477499","https://openalex.org/W2037466124","https://openalex.org/W2038294038","https://openalex.org/W2040430883","https://openalex.org/W2042426842","https://openalex.org/W2042821764","https://openalex.org/W2045804567","https://openalex.org/W2058488568","https://openalex.org/W2059704497","https://openalex.org/W2061603512","https://openalex.org/W2063148187","https://openalex.org/W2065695776","https://openalex.org/W2068598910","https://openalex.org/W2069368135","https://openalex.org/W2071477860","https://openalex.org/W2073295417","https://openalex.org/W2074974933","https://openalex.org/W2076384470","https://openalex.org/W2077767094","https://openalex.org/W2080915872","https://openalex.org/W2090597220","https://openalex.org/W2095082147","https://openalex.org/W2095291179","https://openalex.org/W2099882810","https://openalex.org/W2100762371","https://openalex.org/W2110720586","https://openalex.org/W2111678533","https://openalex.org/W2124433916","https://openalex.org/W2137961176","https://openalex.org/W2139729230","https://openalex.org/W2143015618","https://openalex.org/W2143907120","https://openalex.org/W2145080987","https://openalex.org/W2147375079","https://openalex.org/W2149190057","https://openalex.org/W2151660617","https://openalex.org/W2154170498","https://openalex.org/W2156897641","https://openalex.org/W2159423248","https://openalex.org/W2165531578","https://openalex.org/W2167095271","https://openalex.org/W2169139395","https://openalex.org/W2188905621","https://openalex.org/W2216095137","https://openalex.org/W2285989687","https://openalex.org/W2296196972","https://openalex.org/W2298164671","https://openalex.org/W2326121756","https://openalex.org/W2340542419","https://openalex.org/W2343540188","https://openalex.org/W2346626276","https://openalex.org/W2399947804","https://openalex.org/W2469268362","https://openalex.org/W2525313139","https://openalex.org/W2566932600","https://openalex.org/W2576421220","https://openalex.org/W2596144742","https://openalex.org/W2600107558","https://openalex.org/W2613483874","https://openalex.org/W2624833241","https://openalex.org/W2744975075","https://openalex.org/W2772412764","https://openalex.org/W2801926117","https://openalex.org/W2802640417","https://openalex.org/W2898217533","https://openalex.org/W4210574564","https://openalex.org/W4296941332"],"related_works":["https://openalex.org/W1932918058","https://openalex.org/W2908177692","https://openalex.org/W4414943476","https://openalex.org/W3155926039","https://openalex.org/W2624269248","https://openalex.org/W3138833086","https://openalex.org/W2764187901","https://openalex.org/W3033223036","https://openalex.org/W2111189727","https://openalex.org/W2969453556"],"abstract_inverted_index":{"Recent":[0],"studies":[1],"have":[2],"shown":[3],"renal":[4,24,47,119],"protective":[5],"effects":[6],"of":[7,39,83,91,100,113,123],"bioelectric":[8],"approaches,":[9],"including":[10],"ultrasound":[11],"treatment,":[12],"electrical":[13],"vagus":[14],"nerve":[15],"stimulation,":[16],"and":[17,121],"optogenetic":[18],"brainstem":[19],"C1":[20,45],"neuron":[21],"stimulation.":[22],"The":[23],"protection":[25,48,87,120],"acquired":[26],"by":[27,51,95],"all":[28,59],"three":[29,60,97,105],"modalities":[30,106],"was":[31,49],"lost":[32],"in":[33,88,118],"splenectomized":[34],"mice":[35],"and/or":[36],"\u03b17":[37],"subunit":[38],"the":[40,67,80,101,114],"nicotinic":[41],"acetylcholine":[42],"receptor-deficient":[43],"mice.":[44],"neuron-mediated":[46],"blocked":[50],"\u03b22-adrenergic":[52],"receptor":[53],"antagonist.":[54],"These":[55],"findings":[56],"indicate":[57],"that":[58],"methods":[61],"commonly,":[62],"at":[63],"least":[64],"partially,":[65],"activate":[66],"cholinergic":[68],"anti-inflammatory":[69],"pathway,":[70],"a":[71,110],"well-studied":[72],"neuroimmune":[73,84,115],"pathway.":[74],"In":[75],"this":[76],"article,":[77],"we":[78],"summarize":[79],"current":[81],"understanding":[82],"axis-mediated":[85],"kidney":[86,93],"preclinical":[89],"models":[90],"acute":[92],"injury":[94],"these":[96,104],"modalities.":[98],"Examination":[99],"differences":[102],"among":[103],"might":[107],"lead":[108],"to":[109],"further":[111],"elucidation":[112],"axis":[116],"involved":[117],"is":[122],"interest":[124],"for":[125],"developing":[126],"new":[127],"therapeutic":[128],"approaches.":[129]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-08-31T00:00:00"}