{"id":"https://openalex.org/W2887673236","doi":"https://doi.org/10.1016/j.jcv.2018.08.005","title":"Comparing molecular quantification of herpes simplex virus (HSV) in cerebrospinal fluid (CSF) with quantitative structural and functional disease severity in patients with HSV encephalitis (HSVE): Implications for improved therapeutic approaches","display_name":"Comparing molecular quantification of herpes simplex virus (HSV) in cerebrospinal fluid (CSF) with quantitative structural and functional disease severity in patients with HSV encephalitis (HSVE): Implications for improved therapeutic approaches","publication_year":2018,"publication_date":"2018-08-18","ids":{"openalex":"https://openalex.org/W2887673236","doi":"https://doi.org/10.1016/j.jcv.2018.08.005","mag":"2887673236","pmid":"https://pubmed.ncbi.nlm.nih.gov/30170224"},"language":"en","primary_location":{"id":"doi:10.1016/j.jcv.2018.08.005","doi":"https://doi.org/10.1016/j.jcv.2018.08.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jcv.2018.08.005","pdf_url":null,"source":{"id":"https://openalex.org/S6589812","display_name":"Journal of Clinical Virology","issn_l":"1386-6532","issn":["1386-6532","1873-5967"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055005543","display_name":"Kacy A. Ramirez","orcid":"https://orcid.org/0000-0002-1773-8568","observed_orcids":["https://orcid.org/0000-0002-1773-8568"]},"institutions":[{"id":"https://openalex.org/I1313298211","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313298211","https://openalex.org/I2802152183"]},{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]},{"id":"https://openalex.org/I4210156806","display_name":"Le Bonheur Children's Hospital","ror":"https://ror.org/056wg8a82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210156806"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kacy A. Ramirez","raw_affiliation_strings":["LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States; St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, United States. Electronic address: kramirez@wakehealth.edu","Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States","St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, United States"],"raw_orcid":"https://orcid.org/0000-0002-1773-8568","affiliations":[{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States; St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, United States. Electronic address: kramirez@wakehealth.edu","institution_ids":["https://openalex.org/I1313298211","https://openalex.org/I160606119","https://openalex.org/I4210156806"]},{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I4210156806"]},{"raw_affiliation_string":"St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, United States","institution_ids":["https://openalex.org/I1313298211"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024558649","display_name":"Asim F. Choudhri","orcid":"https://orcid.org/0000-0002-3154-6319","observed_orcids":["https://orcid.org/0000-0002-3154-6319"]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]},{"id":"https://openalex.org/I4210156806","display_name":"Le Bonheur Children's Hospital","ror":"https://ror.org/056wg8a82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210156806"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Asim F. Choudhri","raw_affiliation_strings":["LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States"],"raw_orcid":"https://orcid.org/0000-0002-3154-6319","affiliations":[{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119","https://openalex.org/I4210156806"]},{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I4210156806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108480022","display_name":"Anami R. Patel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]},{"id":"https://openalex.org/I4210156806","display_name":"Le Bonheur Children's Hospital","ror":"https://ror.org/056wg8a82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210156806"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anami Patel","raw_affiliation_strings":["LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119","https://openalex.org/I4210156806"]},{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I4210156806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080964612","display_name":"Noel T. Lenny","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]},{"id":"https://openalex.org/I4210156806","display_name":"Le Bonheur Children's Hospital","ror":"https://ror.org/056wg8a82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210156806"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Noel T. Lenny","raw_affiliation_strings":["LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119","https://openalex.org/I4210156806"]},{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I4210156806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065609035","display_name":"Rebecca Thompson","orcid":"https://orcid.org/0000-0003-3126-6859","observed_orcids":["https://orcid.org/0000-0003-3126-6859"]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rebecca E. Thompson","raw_affiliation_strings":["Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022517071","display_name":"Leslie Berkelhammer Greenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]},{"id":"https://openalex.org/I4210156806","display_name":"Le Bonheur Children's Hospital","ror":"https://ror.org/056wg8a82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210156806"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leslie Berkelhammer Greenberg","raw_affiliation_strings":["LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119","https://openalex.org/I4210156806"]},{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I4210156806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067386946","display_name":"Nancy Clanton Watson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]},{"id":"https://openalex.org/I4210156806","display_name":"Le Bonheur Children's Hospital","ror":"https://ror.org/056wg8a82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210156806"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy Clanton Watson","raw_affiliation_strings":["LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119","https://openalex.org/I4210156806"]},{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I4210156806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016812694","display_name":"Mehmet Ko\u00e7ak","orcid":"https://orcid.org/0000-0002-3386-1734","observed_orcids":["https://orcid.org/0000-0002-3386-1734","https://orcid.org/0000-0003-0782-390X"]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mehmet Kocak","raw_affiliation_strings":["Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036771694","display_name":"John P. DeVincenzo","orcid":"https://orcid.org/0000-0003-2655-344X","observed_orcids":["https://orcid.org/0000-0003-2655-344X"]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]},{"id":"https://openalex.org/I4210156806","display_name":"Le Bonheur Children's Hospital","ror":"https://ror.org/056wg8a82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210156806"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"John P. DeVincenzo","raw_affiliation_strings":["LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, 858 Madison Avenue, G01 Molecular Science Bldg, Memphis, TN, 38163, United States; Children's Foundation Research Institute, 50 North Dunlap, Room 401, Memphis, TN, 38105, United States. Electronic address: jdevince@uthsc.edu","Children's Foundation Research Institute, 50 North Dunlap, Room 401, Memphis, TN, 38105, United States","Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, 858 Madison Avenue, G01 Molecular Science Bldg, Memphis, TN, 38163, United States","Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States; Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, 858 Madison Avenue, G01 Molecular Science Bldg, Memphis, TN, 38163, United States; Children's Foundation Research Institute, 50 North Dunlap, Room 401, Memphis, TN, 38105, United States. Electronic address: jdevince@uthsc.edu","institution_ids":["https://openalex.org/I160606119","https://openalex.org/I4210156806"]},{"raw_affiliation_string":"Children's Foundation Research Institute, 50 North Dunlap, Room 401, Memphis, TN, 38105, United States","institution_ids":[]},{"raw_affiliation_string":"Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, 858 Madison Avenue, G01 Molecular Science Bldg, Memphis, TN, 38163, United States","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 461R, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I160606119"]},{"raw_affiliation_string":"LeBonheur Children's Hospital, 848 Adams Ave, Memphis, TN, 38103, United States","institution_ids":["https://openalex.org/I4210156806"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5036771694","https://openalex.org/A5055005543"],"corresponding_institution_ids":["https://openalex.org/I1313298211","https://openalex.org/I160606119","https://openalex.org/I4210156806"],"apc_list":{"value":4210,"currency":"USD","value_usd":4210},"apc_paid":null,"fwci":0.9749,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.75498383,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"107","issue":null,"first_page":"29","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13201","display_name":"Infectious Encephalopathies and Encephalitis","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herpes-simplex-encephalitis","display_name":"herpes simplex encephalitis","score":0.9919999837875366},{"id":"https://openalex.org/keywords/cerebrospinal-fluid-viral-load","display_name":"cerebrospinal fluid viral load","score":0.9589999914169312},{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-1","display_name":"herpes simplex virus type 1","score":0.7239999771118164},{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-2","display_name":"herpes simplex virus type 2","score":1.0},{"id":"https://openalex.org/keywords/newborns","display_name":"neonates","score":0.7900000214576721},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.746999979019165},{"id":"https://openalex.org/keywords/mri-lesion-volume","display_name":"MRI lesion volume","score":0.6010000109672546},{"id":"https://openalex.org/keywords/cerebrospinal-fluid-protein","display_name":"cerebrospinal fluid protein","score":0.8629999756813049},{"id":"https://openalex.org/keywords/acyclovir","display_name":"acyclovir","score":0.8289999961853027},{"id":"https://openalex.org/keywords/long-term-clinical-outcomes","display_name":"long-term clinical outcomes","score":0.6539999842643738},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.796999990940094},{"id":"https://openalex.org/keywords/host-inflammatory-response","display_name":"host inflammatory response","score":0.7419999837875366},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.5109999775886536},{"id":"https://openalex.org/keywords/antiviral-treatment-response","display_name":"antiviral treatment response","score":0.5440000295639038}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8169841766357422},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.7710294723510742},{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.7694379091262817},{"id":"https://openalex.org/C83455156","wikidata":"https://www.wikidata.org/wiki/Q199615","display_name":"Encephalitis","level":3,"score":0.6738306283950806},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.534654974937439},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5331112146377563},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5221110582351685},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.47363606095314026},{"id":"https://openalex.org/C33619753","wikidata":"https://www.wikidata.org/wiki/Q5014091","display_name":"CSF albumin","level":3,"score":0.4455721974372864},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.44155991077423096},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.37199220061302185},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3239383399486542},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.2980450391769409}],"mesh":[{"descriptor_ui":"D000212","descriptor_name":"Acyclovir","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":"Q000134","qualifier_name":"cerebrospinal fluid","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018258","descriptor_name":"Herpesvirus 2, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018258","descriptor_name":"Herpesvirus 2, Human","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D018259","descriptor_name":"Herpesvirus 1, Human","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018259","descriptor_name":"Herpesvirus 1, Human","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D020803","descriptor_name":"Encephalitis, Herpes Simplex","qualifier_ui":"Q000134","qualifier_name":"cerebrospinal fluid","is_major_topic":true},{"descriptor_ui":"D020803","descriptor_name":"Encephalitis, Herpes Simplex","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jcv.2018.08.005","doi":"https://doi.org/10.1016/j.jcv.2018.08.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jcv.2018.08.005","pdf_url":null,"source":{"id":"https://openalex.org/S6589812","display_name":"Journal of Clinical Virology","issn_l":"1386-6532","issn":["1386-6532","1873-5967"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Virology","raw_type":"journal-article"},{"id":"pmid:30170224","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30170224","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8100000023841858,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W169105841","https://openalex.org/W1539384503","https://openalex.org/W1579163479","https://openalex.org/W1603121691","https://openalex.org/W1963622800","https://openalex.org/W1988219883","https://openalex.org/W1998749795","https://openalex.org/W2008938292","https://openalex.org/W2011359693","https://openalex.org/W2014737971","https://openalex.org/W2015828165","https://openalex.org/W2017617967","https://openalex.org/W2025444660","https://openalex.org/W2040055625","https://openalex.org/W2053611532","https://openalex.org/W2074740826","https://openalex.org/W2080842341","https://openalex.org/W2081900328","https://openalex.org/W2108914157","https://openalex.org/W2117702644","https://openalex.org/W2127472356","https://openalex.org/W2132548307","https://openalex.org/W2137326094","https://openalex.org/W2141780157","https://openalex.org/W2159465232","https://openalex.org/W2160598498","https://openalex.org/W2167622530","https://openalex.org/W2324411241","https://openalex.org/W2333553600","https://openalex.org/W6606770687"],"related_works":["https://openalex.org/W4232289548","https://openalex.org/W2051461190","https://openalex.org/W2017617967","https://openalex.org/W2037732815","https://openalex.org/W2117702644","https://openalex.org/W2011359693","https://openalex.org/W1963622800","https://openalex.org/W2338746980","https://openalex.org/W2045301009","https://openalex.org/W2586631498"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2018-08-22T00:00:00"}