{"id":"https://openalex.org/W2886929590","doi":"https://doi.org/10.21767/2472-1123-c2-004","title":"A new generation of orally available tubulin inhibitors: the discovery and development","display_name":"A new generation of orally available tubulin inhibitors: the discovery and development","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2886929590","doi":"https://doi.org/10.21767/2472-1123-c2-004","mag":"2886929590"},"language":"en","primary_location":{"id":"doi:10.21767/2472-1123-c2-004","doi":"https://doi.org/10.21767/2472-1123-c2-004","is_oa":false,"landing_page_url":"https://doi.org/10.21767/2472-1123-c2-004","pdf_url":null,"source":{"id":"https://openalex.org/S4210206159","display_name":"Journal of Organic & Inorganic Chemistry","issn_l":"2472-1123","issn":["2472-1123"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Organic & Inorganic Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100318325","display_name":"W\u011bi Li","orcid":"https://orcid.org/0000-0002-9522-4474","observed_orcids":["https://orcid.org/0000-0002-9522-4474","https://orcid.org/0000-0003-4136-3409","https://orcid.org/0009-0009-9141-6389"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Wei Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5100318325"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0886161,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"04","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.6753000020980835,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.6753000020980835,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.29589998722076416,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11752","display_name":"Cancer Treatment and Pharmacology","score":0.016300000250339508,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tubulin-polymerization-inhibitors","display_name":"tubulin polymerization inhibitors","score":0.9760000109672546},{"id":"https://openalex.org/keywords/oral-drug-delivery","display_name":"oral drug delivery","score":0.5649999976158142},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.7310000061988831},{"id":"https://openalex.org/keywords/microtubule-inhibitors","display_name":"microtubule inhibitors","score":0.6769999861717224},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"drug discovery","score":0.8679999709129333},{"id":"https://openalex.org/keywords/drug-development","display_name":"drug development","score":0.6859999895095825}],"concepts":[{"id":"https://openalex.org/C84425145","wikidata":"https://www.wikidata.org/wiki/Q422492","display_name":"Tubulin","level":3,"score":0.5188339948654175},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.42514902353286743},{"id":"https://openalex.org/C3017990168","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Orally active","level":3,"score":0.41341423988342285},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.39298251271247864},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3270847201347351},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3171823024749756},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29946959018707275},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2175959050655365},{"id":"https://openalex.org/C2777056448","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Oral administration","level":2,"score":0.18004021048545837},{"id":"https://openalex.org/C20418707","wikidata":"https://www.wikidata.org/wiki/Q189933","display_name":"Microtubule","level":2,"score":0.15665295720100403},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12333160638809204}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.21767/2472-1123-c2-004","doi":"https://doi.org/10.21767/2472-1123-c2-004","is_oa":false,"landing_page_url":"https://doi.org/10.21767/2472-1123-c2-004","pdf_url":null,"source":{"id":"https://openalex.org/S4210206159","display_name":"Journal of Organic & Inorganic Chemistry","issn_l":"2472-1123","issn":["2472-1123"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Organic & Inorganic Chemistry","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2888874993","https://openalex.org/W7058643073","https://openalex.org/W7048472398","https://openalex.org/W7113759688","https://openalex.org/W4294912087","https://openalex.org/W2399085599","https://openalex.org/W6968552598","https://openalex.org/W2330129498","https://openalex.org/W2584352970","https://openalex.org/W7148220878"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-08-22T00:00:00"}