{"id":"https://openalex.org/W2886830303","doi":"https://doi.org/10.1016/j.ejbas.2018.07.002","title":"Bioactive potential of secondary metabolites derived from medicinal plant endophytes","display_name":"Bioactive potential of secondary metabolites derived from medicinal plant endophytes","publication_year":2018,"publication_date":"2018-08-06","ids":{"openalex":"https://openalex.org/W2886830303","doi":"https://doi.org/10.1016/j.ejbas.2018.07.002","mag":"2886830303"},"language":"en","primary_location":{"id":"doi:10.1016/j.ejbas.2018.07.002","doi":"https://doi.org/10.1016/j.ejbas.2018.07.002","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ejbas.2018.07.002","pdf_url":null,"source":{"id":"https://openalex.org/S2764671201","display_name":"Egyptian Journal of Basic and Applied Sciences","issn_l":"2314-808X","issn":["2314-808X","2589-1561"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Egyptian Journal of Basic and Applied Sciences","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2886830303"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1016/j.ejbas.2018.07.002","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053201956","display_name":"Prabha Palanichamy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13268429","display_name":"Madurai Kamaraj University","ror":"https://ror.org/04c8e9019","country_code":"IN","type":"education","lineage":["https://openalex.org/I13268429"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Prabha Palanichamy","raw_affiliation_strings":["Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India","institution_ids":["https://openalex.org/I13268429"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037489268","display_name":"Govindan Krishnamoorthy","orcid":"https://orcid.org/0000-0002-2706-7577","observed_orcids":["https://orcid.org/0000-0002-2706-7577"]},"institutions":[{"id":"https://openalex.org/I13268429","display_name":"Madurai Kamaraj University","ror":"https://ror.org/04c8e9019","country_code":"IN","type":"education","lineage":["https://openalex.org/I13268429"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Govindan Krishnamoorthy","raw_affiliation_strings":["Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India","institution_ids":["https://openalex.org/I13268429"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023972322","display_name":"Suganya Kannan","orcid":"https://orcid.org/0000-0002-0341-7405","observed_orcids":["https://orcid.org/0000-0002-0341-7405"]},"institutions":[{"id":"https://openalex.org/I13268429","display_name":"Madurai Kamaraj University","ror":"https://ror.org/04c8e9019","country_code":"IN","type":"education","lineage":["https://openalex.org/I13268429"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Suganya Kannan","raw_affiliation_strings":["Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India","institution_ids":["https://openalex.org/I13268429"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075432000","display_name":"Marudhamuthu Murugan","orcid":"https://orcid.org/0000-0002-1624-5374","observed_orcids":["https://orcid.org/0000-0002-1624-5374"]},"institutions":[{"id":"https://openalex.org/I13268429","display_name":"Madurai Kamaraj University","ror":"https://ror.org/04c8e9019","country_code":"IN","type":"education","lineage":["https://openalex.org/I13268429"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Murugan Marudhamuthu","raw_affiliation_strings":["Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India","institution_ids":["https://openalex.org/I13268429"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5075432000"],"corresponding_institution_ids":["https://openalex.org/I13268429"],"apc_list":null,"apc_paid":null,"fwci":4.8383,"has_fulltext":false,"cited_by_count":102,"citation_normalized_percentile":{"value":0.97526763,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"5","issue":"4","first_page":"303","last_page":"312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12934","display_name":"Plant and fungal interactions","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10825","display_name":"Plant Pathogens and Fungal Diseases","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endophytic-fungi","display_name":"endophytic fungi","score":0.9010000228881836},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.9350000023841858},{"id":"https://openalex.org/keywords/secondary-metabolites","display_name":"secondary metabolites","score":0.9589999914169312},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.8550000190734863},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.859000027179718},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.9990000128746033},{"id":"https://openalex.org/keywords/alternariol-methyl-ether","display_name":"alternariol methyl ether","score":0.921999990940094},{"id":"https://openalex.org/keywords/alternaria","display_name":"Alternaria","score":0.9769999980926514},{"id":"https://openalex.org/keywords/fusarium","display_name":"Fusarium","score":0.968999981880188},{"id":"https://openalex.org/keywords/mycelia-sterilia","display_name":"Mycelia sterilia","score":0.9010000228881836},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"drug discovery","score":0.5590000152587891},{"id":"https://openalex.org/keywords/ethyl-acetate-extract","display_name":"ethyl acetate extract","score":0.6370000243186951},{"id":"https://openalex.org/keywords/human-pathogens","display_name":"human pathogens","score":0.6570000052452087}],"concepts":[{"id":"https://openalex.org/C2777347573","wikidata":"https://www.wikidata.org/wiki/Q522244","display_name":"Secondary metabolite","level":3,"score":0.8226022720336914},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.7661595344543457},{"id":"https://openalex.org/C89638049","wikidata":"https://www.wikidata.org/wiki/Q7201546","display_name":"Plant use of endophytic fungi in defense","level":2,"score":0.6869841814041138},{"id":"https://openalex.org/C2779158651","wikidata":"https://www.wikidata.org/wiki/Q188840","display_name":"Medicinal plants","level":2,"score":0.5227332711219788},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.501713752746582},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46970340609550476},{"id":"https://openalex.org/C2779771029","wikidata":"https://www.wikidata.org/wiki/Q133266","display_name":"Alternaria","level":2,"score":0.4663713574409485},{"id":"https://openalex.org/C2779858419","wikidata":"https://www.wikidata.org/wiki/Q407153","display_name":"Ethyl acetate","level":2,"score":0.4652493894100189},{"id":"https://openalex.org/C2781401929","wikidata":"https://www.wikidata.org/wiki/Q5205953","display_name":"DPPH","level":3,"score":0.42442992329597473},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.412977933883667},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3900798559188843},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.38142454624176025},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.33679163455963135},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.31539303064346313},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.29826655983924866},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.23303157091140747},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.18092575669288635},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13925117254257202},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.ejbas.2018.07.002","doi":"https://doi.org/10.1016/j.ejbas.2018.07.002","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ejbas.2018.07.002","pdf_url":null,"source":{"id":"https://openalex.org/S2764671201","display_name":"Egyptian Journal of Basic and Applied Sciences","issn_l":"2314-808X","issn":["2314-808X","2589-1561"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Egyptian Journal of Basic and Applied Sciences","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.ejbas.2018.07.002","doi":"https://doi.org/10.1016/j.ejbas.2018.07.002","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ejbas.2018.07.002","pdf_url":null,"source":{"id":"https://openalex.org/S2764671201","display_name":"Egyptian Journal of Basic and Applied Sciences","issn_l":"2314-808X","issn":["2314-808X","2589-1561"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Egyptian Journal of Basic and Applied Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8503000140190125}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320717","display_name":"Department of Biotechnology, Ministry of Science and Technology, India","ror":"https://ror.org/03tjsyq23"},{"id":"https://openalex.org/F4320320767","display_name":"University Grants Commission","ror":"https://ror.org/04p800546"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W99923813","https://openalex.org/W108945078","https://openalex.org/W1964957521","https://openalex.org/W1970230314","https://openalex.org/W1991775006","https://openalex.org/W1993034915","https://openalex.org/W2012398257","https://openalex.org/W2021995332","https://openalex.org/W2028970994","https://openalex.org/W2030793893","https://openalex.org/W2030909449","https://openalex.org/W2031700878","https://openalex.org/W2043733949","https://openalex.org/W2048629418","https://openalex.org/W2093798800","https://openalex.org/W2096807045","https://openalex.org/W2110173500","https://openalex.org/W2114004260","https://openalex.org/W2127892341","https://openalex.org/W2136249549","https://openalex.org/W2150616283","https://openalex.org/W2150669502","https://openalex.org/W2156505503","https://openalex.org/W2168016781","https://openalex.org/W2276395130","https://openalex.org/W2342101883","https://openalex.org/W2949770324","https://openalex.org/W2974822636","https://openalex.org/W3012267796"],"related_works":["https://openalex.org/W3088864324","https://openalex.org/W4417444158","https://openalex.org/W2974133728","https://openalex.org/W4291139506","https://openalex.org/W3094144674","https://openalex.org/W2355996388","https://openalex.org/W4313211592","https://openalex.org/W4391214002","https://openalex.org/W4411995582"],"abstract_inverted_index":{"Medicinal":[0],"plants":[1,66],"have":[2,34],"been":[3,35],"used":[4],"as":[5,131,204],"an":[6],"alternative":[7],"medicine":[8],"to":[9,39],"promote":[10],"human":[11,128],"health":[12],"and":[13,37,50,102,140,156,168,187,197,225],"longevity":[14],"in":[15,89,161],"many":[16,27],"regions":[17],"of":[18,56,74,82,109,146,195,228],"the":[19,80,198],"world":[20],"since":[21],"ancient":[22],"times.":[23],"In":[24],"recent":[25],"years,":[26],"novel":[28],"secondary":[29,84,107,149,176,200,212],"metabolites":[30,85,108],"from":[31,62,68,214],"higher":[32],"fungi":[33,59,78,96],"isolated":[36,61,95],"reported":[38],"provide":[40],"lead":[41],"compounds":[42],"for":[43,79,222],"new":[44],"drug":[45],"discovery":[46],"like":[47],"antimicrobial,":[48],"antioxidant,":[49],"anticancer":[51,169],"agents,":[52],"etc.":[53],"A":[54],"total":[55],"42":[57],"endophytic":[58,77],"were":[60,97,112,171],"11":[63],"different":[64],"medicinal":[65,75],"collected":[67],"Tamil":[69],"Nadu,":[70],"India.":[71],"The":[72,92,105,174,208],"capability":[73],"plant":[76],"production":[81,151],"bioactive":[83,106,199],"was":[86,159,178,202],"evaluated":[87],"under":[88],"vitro":[90],"conditions.":[91],"most":[93],"frequently":[94],"Alternaria":[98,162,215],"sp.":[99,101,163,216],"Fusarium":[100],"mycelia":[103],"sterilia.":[104],"these":[110],"endophytes":[111],"obtained":[113],"by":[114,180],"liquid-liquid":[115],"extraction":[116],"with":[117,143,152,192],"ethyl":[118],"acetate.":[119],"Among":[120],"which":[121],"15":[122],"showed":[123],"antimicrobial":[124,157],"activity":[125,158,170],"towards":[126],"potential":[127,220],"pathogens":[129],"such":[130],"Escherichia":[132],"coli,":[133],"Salmonella":[134],"typhi,":[135],"Proteus":[136],"mirabilis,":[137],"Staphylococcus":[138],"aureus,":[139],"Corynebacterium":[141],"diphtheriae":[142],"variable":[144],"zone":[145],"inhibition.":[147],"Maximum":[148],"metabolite":[150,177,201,213],"good":[153],"mycelial":[154],"growth":[155],"observed":[160],"MGTMMP031.":[164],"Moreover,":[165],"in-vitro":[166],"antioxidant":[167],"also":[172],"evaluated.":[173],"crude":[175],"characterized":[179],"ultraviolet":[181],"spectrum":[182,185],"(UV),":[183],"infrared":[184],"(FT-IR)":[186],"thin":[188],"layer":[189],"chromatography":[190],"(TLC)":[191],"Rf":[193],"value":[194],"0.35":[196],"identified":[203],"alternariol":[205],"methyl":[206],"ether.":[207],"results":[209],"concluded":[210],"that":[211],"may":[217],"represent":[218],"a":[219],"ingredient":[221],"pharmaceutical":[223],"application":[224],"are":[226],"worthy":[227],"future":[229],"study.":[230]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":16},{"year":2021,"cited_by_count":21},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":5}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2018-08-22T00:00:00"}