{"id":"https://openalex.org/W2886762065","doi":"https://doi.org/10.1111/wrr.12666","title":"Blastema formation and periosteal ossification in the regenerating adult mouse digit","display_name":"Blastema formation and periosteal ossification in the regenerating adult mouse digit","publication_year":2018,"publication_date":"2018-05-01","ids":{"openalex":"https://openalex.org/W2886762065","doi":"https://doi.org/10.1111/wrr.12666","mag":"2886762065","pmid":"https://pubmed.ncbi.nlm.nih.gov/30120800"},"language":"en","primary_location":{"id":"doi:10.1111/wrr.12666","doi":"https://doi.org/10.1111/wrr.12666","is_oa":false,"landing_page_url":"https://doi.org/10.1111/wrr.12666","pdf_url":null,"source":{"id":"https://openalex.org/S121715350","display_name":"Wound Repair and Regeneration","issn_l":"1067-1927","issn":["1067-1927","1524-475X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wound Repair and Regeneration","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051378797","display_name":"Lindsay Dawson","orcid":"https://orcid.org/0000-0002-4903-6050","observed_orcids":["https://orcid.org/0000-0002-4903-6050"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lindsay A. Dawson","raw_affiliation_strings":["Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas","Lindsay A. Dawson, Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas 77843. Tel: +1 979-845-1730","Reprint requests:"],"raw_orcid":"https://orcid.org/0000-0002-4903-6050","affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","institution_ids":["https://openalex.org/I114832834"]},{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas","institution_ids":["https://openalex.org/I91045830"]},{"raw_affiliation_string":"Lindsay A. Dawson, Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas 77843. Tel: +1 979-845-1730","institution_ids":["https://openalex.org/I91045830"]},{"raw_affiliation_string":"Reprint requests:","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073941755","display_name":"Paula P. Schanes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paula P. Schanes","raw_affiliation_strings":["Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","institution_ids":["https://openalex.org/I114832834"]},{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009572165","display_name":"Patrick Kim","orcid":"https://orcid.org/0000-0002-9933-8487","observed_orcids":["https://orcid.org/0000-0002-9933-8487"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick Kim","raw_affiliation_strings":["Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","institution_ids":["https://openalex.org/I114832834"]},{"raw_affiliation_string":"Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030417412","display_name":"Felisha M. Imholt","orcid":"https://orcid.org/0000-0003-3026-1546","observed_orcids":["https://orcid.org/0000-0003-3026-1546"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Felisha M. Imholt","raw_affiliation_strings":["Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027175160","display_name":"Osama Qureshi","orcid":"https://orcid.org/0000-0002-2495-7726","observed_orcids":["https://orcid.org/0000-0002-2495-7726"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Osama Qureshi","raw_affiliation_strings":["Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017158408","display_name":"Connor P. Dolan","orcid":"https://orcid.org/0000-0001-7002-9341","observed_orcids":["https://orcid.org/0000-0001-7002-9341"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Connor P. Dolan","raw_affiliation_strings":["Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","institution_ids":["https://openalex.org/I114832834"]},{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100681418","display_name":"Ling Yu","orcid":"https://orcid.org/0000-0002-8781-3033","observed_orcids":["https://orcid.org/0000-0002-8781-3033"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ling Yu","raw_affiliation_strings":["Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","institution_ids":["https://openalex.org/I114832834"]},{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mingquan Yan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mingquan Yan","raw_affiliation_strings":["Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","institution_ids":["https://openalex.org/I114832834"]},{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020298383","display_name":"Katherine  N. Zimmel","orcid":"https://orcid.org/0000-0002-8243-6953","observed_orcids":["https://orcid.org/0000-0002-8243-6953"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katherine N. Zimmel","raw_affiliation_strings":["Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","institution_ids":["https://openalex.org/I114832834"]},{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018547938","display_name":"Alyssa  R. Falck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alyssa R. Falck","raw_affiliation_strings":["Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi","Department of Veterinary Integrative Biosciences College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department of Veterinary Integrative Biosciences College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016223164","display_name":"Ken Muneoka","orcid":"https://orcid.org/0000-0002-7520-6869","observed_orcids":["https://orcid.org/0000-0002-7520-6869"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ken Muneoka","raw_affiliation_strings":["Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana","institution_ids":["https://openalex.org/I114832834"]},{"raw_affiliation_string":"Department of Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical Sciences, Texas A&M University College Station Texas","institution_ids":["https://openalex.org/I91045830"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5051378797"],"corresponding_institution_ids":["https://openalex.org/I114832834","https://openalex.org/I91045830"],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":null,"fwci":1.2225,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.78398842,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"26","issue":"3","first_page":"263","last_page":"273"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12789","display_name":"Planarian Biology and Electrostimulation","score":0.6718999743461609,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12789","display_name":"Planarian Biology and Electrostimulation","score":0.6718999743461609,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.0714000016450882,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13107","display_name":"Congenital limb and hand anomalies","score":0.03310000151395798,"subfield":{"id":"https://openalex.org/subfields/1309","display_name":"Developmental Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blastema-formation","display_name":"blastema formation","score":0.9229999780654907},{"id":"https://openalex.org/keywords/periosteal-ossification","display_name":"periosteal ossification","score":0.9629999995231628},{"id":"https://openalex.org/keywords/digit-tip-regeneration","display_name":"digit tip regeneration","score":0.7260000109672546},{"id":"https://openalex.org/keywords/epimorphosis","display_name":"epimorphosis","score":0.8930000066757202},{"id":"https://openalex.org/keywords/periosteum","display_name":"periosteum","score":0.7450000047683716},{"id":"https://openalex.org/keywords/endosteum","display_name":"endosteum","score":0.8349999785423279},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.675000011920929},{"id":"https://openalex.org/keywords/distal-phalanx","display_name":"distal phalanx","score":0.6909999847412109}],"concepts":[{"id":"https://openalex.org/C78214289","wikidata":"https://www.wikidata.org/wiki/Q882043","display_name":"Blastema","level":3,"score":0.9559859037399292},{"id":"https://openalex.org/C2777674748","wikidata":"https://www.wikidata.org/wiki/Q367423","display_name":"Periosteum","level":2,"score":0.8373685479164124},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.753806471824646},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.7033445835113525},{"id":"https://openalex.org/C94957134","wikidata":"https://www.wikidata.org/wiki/Q82990","display_name":"Numerical digit","level":2,"score":0.4725082814693451},{"id":"https://openalex.org/C203635412","wikidata":"https://www.wikidata.org/wiki/Q17007432","display_name":"Compartment (ship)","level":2,"score":0.4519384801387787},{"id":"https://openalex.org/C8337478","wikidata":"https://www.wikidata.org/wiki/Q1777289","display_name":"Bone healing","level":2,"score":0.4419533610343933},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3968944847583771},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3729736804962158},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3640051484107971},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24299857020378113},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0},{"id":"https://openalex.org/C94375191","wikidata":"https://www.wikidata.org/wiki/Q11205","display_name":"Arithmetic","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000671","descriptor_name":"Amputation, Surgical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010012","descriptor_name":"Osteogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010521","descriptor_name":"Periosteum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012038","descriptor_name":"Regeneration","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018919","descriptor_name":"Neovascularization, Physiologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044968","descriptor_name":"Regenerative Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D050277","descriptor_name":"Toe Phalanges","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":false},{"descriptor_ui":"D050277","descriptor_name":"Toe Phalanges","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/wrr.12666","doi":"https://doi.org/10.1111/wrr.12666","is_oa":false,"landing_page_url":"https://doi.org/10.1111/wrr.12666","pdf_url":null,"source":{"id":"https://openalex.org/S121715350","display_name":"Wound Repair and Regeneration","issn_l":"1067-1927","issn":["1067-1927","1524-475X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wound Repair and Regeneration","raw_type":"journal-article"},{"id":"pmid:30120800","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30120800","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2038759816","display_name":null,"funder_award_id":"W911NF\u201006\u20101\u20100161","funder_id":"https://openalex.org/F4320332180","funder_display_name":"Defense Advanced Research Projects Agency"}],"funders":[{"id":"https://openalex.org/F4320310164","display_name":"Texas A and M University","ror":"https://ror.org/01f5ytq51"},{"id":"https://openalex.org/F4320332180","display_name":"Defense Advanced Research Projects Agency","ror":"https://ror.org/02caytj08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W572025462","https://openalex.org/W1572740406","https://openalex.org/W1767456499","https://openalex.org/W1893231737","https://openalex.org/W1970097521","https://openalex.org/W1973666758","https://openalex.org/W1980115934","https://openalex.org/W1982487793","https://openalex.org/W1984758838","https://openalex.org/W1987189093","https://openalex.org/W1988796528","https://openalex.org/W1990113175","https://openalex.org/W1992663358","https://openalex.org/W1993817188","https://openalex.org/W1995963486","https://openalex.org/W1997473015","https://openalex.org/W2003054685","https://openalex.org/W2006557479","https://openalex.org/W2013702641","https://openalex.org/W2022789026","https://openalex.org/W2025909669","https://openalex.org/W2036947691","https://openalex.org/W2041497605","https://openalex.org/W2062453614","https://openalex.org/W2067452822","https://openalex.org/W2070255306","https://openalex.org/W2072100512","https://openalex.org/W2072969513","https://openalex.org/W2080052043","https://openalex.org/W2081344096","https://openalex.org/W2084087844","https://openalex.org/W2086039962","https://openalex.org/W2086859574","https://openalex.org/W2091103338","https://openalex.org/W2109293470","https://openalex.org/W2120989136","https://openalex.org/W2138989752","https://openalex.org/W2143769859","https://openalex.org/W2146204519","https://openalex.org/W2169127853","https://openalex.org/W2174993055","https://openalex.org/W2231321683","https://openalex.org/W2409492169","https://openalex.org/W2428872011","https://openalex.org/W2464410938","https://openalex.org/W2585423788","https://openalex.org/W2612559606","https://openalex.org/W2621566669","https://openalex.org/W2626342377","https://openalex.org/W2777692101","https://openalex.org/W2789489527"],"related_works":["https://openalex.org/W2956607278","https://openalex.org/W2067452822","https://openalex.org/W3081428507","https://openalex.org/W2084087844","https://openalex.org/W3000321238","https://openalex.org/W2948735271","https://openalex.org/W1995326337","https://openalex.org/W2115256283","https://openalex.org/W4210859534","https://openalex.org/W2612559606"],"abstract_inverted_index":{"While":[0],"mammals":[1],"cannot":[2],"regenerate":[3,47],"amputated":[4,49,166],"limbs,":[5],"mice":[6],"and":[7,31,76,91,104,117,132,138,168,179,243],"humans":[8],"have":[9],"regenerative":[10,55,78],"ability":[11],"restricted":[12],"to":[13,46,71,88,114,142,225],"amputations":[14],"transecting":[15],"the":[16,20,26,34,48,54,94,107,115,122,136,144,150,165,177,187,191,200,219,226,240,245],"digit":[17,64,181],"tip,":[18],"including":[19],"terminal":[21],"phalanx":[22],"(P3).":[23],"In":[24,98],"mice,":[25],"regeneration":[27,192,220,254],"process":[28],"is":[29,130,174,184,216,247],"epimorphic":[30,253],"mediated":[32],"by":[33],"formation":[35,52,75,85,161,236],"of":[36,40,110,124,158,193,221],"a":[37,58,68,154],"blastema":[38,74,84,145,235],"comprised":[39],"undifferentiated":[41],"proliferating":[42],"cells":[43,105,133],"that":[44,82,162,197,213,234,244],"differentiate":[45],"structures.":[50],"Blastema":[51],"distinguishes":[53],"response":[56,242],"from":[57,164],"scar-forming":[59],"healing":[60,101,241],"response.":[61,97],"The":[62],"mouse":[63],"tip":[65],"serves":[66],"as":[67,153],"preclinical":[69],"model":[70],"investigate":[72],"mammalian":[73],"endogenous":[77],"capabilities.":[79],"We":[80],"report":[81],"P3":[83],"initiates":[86,237],"prior":[87],"epidermal":[89,128],"closure":[90,129],"concurrent":[92],"with":[93,135,149,190],"bone":[95,119,126,160,196,203,223],"histolytic":[96],"this":[99,214],"early":[100,108,238],"response,":[102],"proliferation":[103],"entering":[106],"stages":[109],"osteogenesis":[111],"are":[112],"localized":[113],"periosteal":[116,137],"endosteal":[118,139],"compartments.":[120],"After":[121],"completion":[123],"stump":[125,167],"histolysis,":[127],"completed":[131],"associated":[134,148],"compartments":[140],"blend":[141],"form":[143],"proper.":[146],"Osteogenesis":[147],"periosteum":[151,246],"occurs":[152],"polarized":[155],"progressive":[156],"wave":[157],"new":[159,195,222],"extends":[163],"restores":[169],"skeletal":[170],"length.":[171],"Bone":[172],"patterning":[173],"restored":[175],"along":[176],"proximal-distal":[178],"medial":[180],"axes,":[182],"but":[183],"imperfect":[185],"in":[186,206,239,255],"dorsal-ventral":[188],"axis":[189],"excessive":[194],"accounts":[198],"for":[199,218,251],"enhanced":[201],"regenerated":[202],"volume":[204],"noted":[205],"previous":[207],"studies.":[208],"Periosteum":[209],"depletion":[210],"studies":[211,231],"show":[212],"compartment":[215],"required":[217],"distal":[224],"original":[227],"amputation":[228],"plane.":[229],"These":[230],"provide":[232],"evidence":[233],"an":[248],"essential":[249],"tissue":[250],"successful":[252],"mammals.":[256]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2018-08-22T00:00:00"}