{"id":"https://openalex.org/W2886228551","doi":"https://doi.org/10.31871/wjrr.6.1.18","title":"Effects of Olmesartan and Azilsartan on Albuminuria and the Intrarenal Renin-Angiotensin System","display_name":"Effects of Olmesartan and Azilsartan on Albuminuria and the Intrarenal Renin-Angiotensin System","publication_year":2018,"publication_date":"2018-01-11","ids":{"openalex":"https://openalex.org/W2886228551","doi":"https://doi.org/10.31871/wjrr.6.1.18","mag":"2886228551","pmid":"https://pubmed.ncbi.nlm.nih.gov/29683146","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5909402"},"language":"en","primary_location":{"id":"doi:10.31871/wjrr.6.1.18","doi":"https://doi.org/10.31871/wjrr.6.1.18","is_oa":true,"landing_page_url":"https://doi.org/10.31871/wjrr.6.1.18","pdf_url":"https://doi.org/10.31871/wjrr.6.1.18","source":{"id":"https://openalex.org/S4306534943","display_name":"World Journal of Research and Review","issn_l":"2455-3956","issn":["2455-3956"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Research and Review","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.31871/wjrr.6.1.18","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076551054","display_name":"Takeshi Takami","orcid":"https://orcid.org/0000-0003-4944-2304","observed_orcids":["https://orcid.org/0000-0003-4944-2304"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takeshi Takami","raw_affiliation_strings":["Department of Internal Medicine , Clinic Jingumae , Kashihara , Japan,","Department of Internal Medicine, Clinic Jingumae, Kashihara, Japan,","Faculty of Medicine, Kagawa University, Kagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine , Clinic Jingumae , Kashihara , Japan,","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Clinic Jingumae, Kashihara, Japan,","institution_ids":[]},{"raw_affiliation_string":"Faculty of Medicine, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045410612","display_name":"Sadanori Okada","orcid":"https://orcid.org/0000-0002-3097-8152","observed_orcids":["https://orcid.org/0000-0002-3097-8152"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]},{"id":"https://openalex.org/I64926303","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14","country_code":"JP","type":"education","lineage":["https://openalex.org/I64926303"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Sadanori Okada","raw_affiliation_strings":["Department of Cardiovascular Medicine , Nara medical University , Kashihara , Japan","Department of Cardiovascular Medicine, Nara medical University, Kashihara, Japan","Faculty of Medicine, Kagawa University, Kagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine , Nara medical University , Kashihara , Japan","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Department of Cardiovascular Medicine, Nara medical University, Kashihara, Japan","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Faculty of Medicine, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066956159","display_name":"Yoshihiko Saito","orcid":"https://orcid.org/0000-0001-5574-3571","observed_orcids":["https://orcid.org/0000-0001-5574-3571"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]},{"id":"https://openalex.org/I64926303","display_name":"Nara Medical University","ror":"https://ror.org/045ysha14","country_code":"JP","type":"education","lineage":["https://openalex.org/I64926303"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshihiko Saito","raw_affiliation_strings":["Professor of Department of Cardiovascular Medicine , Nara medical University , Kashihara ,, Japan","Faculty of Medicine, Kagawa University, Kagawa, Japan","Professor of Department of Cardiovascular Medicine, Nara medical University, Kashihara,, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Professor of Department of Cardiovascular Medicine , Nara medical University , Kashihara ,, Japan","institution_ids":["https://openalex.org/I64926303"]},{"raw_affiliation_string":"Faculty of Medicine, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]},{"raw_affiliation_string":"Professor of Department of Cardiovascular Medicine, Nara medical University, Kashihara,, Japan","institution_ids":["https://openalex.org/I64926303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003721455","display_name":"Yoko Nishijima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]},{"id":"https://openalex.org/I4210135297","display_name":"Kagawa University Hospital","ror":"https://ror.org/033sspj46","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I201933988","https://openalex.org/I4210135297"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoko Nishijima","raw_affiliation_strings":["Department of CardioRenal and CerebroVascular Medicine , Faculty of Medicine , Kagawa University , Kagawa , Japan","Department of CardioRenal and CerebroVascular Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan","Faculty of Medicine, Kagawa University, Kagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of CardioRenal and CerebroVascular Medicine , Faculty of Medicine , Kagawa University , Kagawa , Japan","institution_ids":["https://openalex.org/I201933988","https://openalex.org/I4210135297"]},{"raw_affiliation_string":"Department of CardioRenal and CerebroVascular Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]},{"raw_affiliation_string":"Faculty of Medicine, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049403883","display_name":"Hiroyuki Kobori","orcid":"https://orcid.org/0000-0001-5128-5059","observed_orcids":["https://orcid.org/0000-0001-5128-5059"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]},{"id":"https://openalex.org/I79072001","display_name":"International University of Health and Welfare","ror":"https://ror.org/053d3tv41","country_code":"JP","type":"education","lineage":["https://openalex.org/I79072001"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyuki Kobori","raw_affiliation_strings":["Professor in the Departments of Pharmacology and of Nephrology , School of Medicine , International University of Health and Welfare , Narita , Japan","Faculty of Medicine, Kagawa University, Kagawa, Japan","Professor in the Departments of Pharmacology and of Nephrology, School of Medicine, International University of Health and Welfare, Narita, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Professor in the Departments of Pharmacology and of Nephrology , School of Medicine , International University of Health and Welfare , Narita , Japan","institution_ids":["https://openalex.org/I79072001"]},{"raw_affiliation_string":"Faculty of Medicine, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]},{"raw_affiliation_string":"Professor in the Departments of Pharmacology and of Nephrology, School of Medicine, International University of Health and Welfare, Narita, Japan","institution_ids":["https://openalex.org/I79072001"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049861668","display_name":"Akira Nishiyama","orcid":"https://orcid.org/0000-0001-5971-820X","observed_orcids":["https://orcid.org/0000-0001-5971-820X"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Nishiyama","raw_affiliation_strings":["Faculty of Medicine , Kagawa University , Kagawa , Japan","Professor of the Department of Pharmacology ,","Faculty of Medicine, Kagawa University, Kagawa, Japan","Professor of the Department of Pharmacology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine , Kagawa University , Kagawa , Japan","institution_ids":["https://openalex.org/I201933988"]},{"raw_affiliation_string":"Professor of the Department of Pharmacology ,","institution_ids":[]},{"raw_affiliation_string":"Faculty of Medicine, Kagawa University, Kagawa, Japan","institution_ids":["https://openalex.org/I201933988"]},{"raw_affiliation_string":"Professor of the Department of Pharmacology,","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5747,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.71154795,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"6","issue":"1","first_page":"7","last_page":"10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.9110999703407288,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.9110999703407288,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.06880000233650208,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/olmesartan","display_name":"olmesartan","score":0.9990000128746033},{"id":"https://openalex.org/keywords/azilsartan","display_name":"azilsartan","score":1.0},{"id":"https://openalex.org/keywords/angiotensin-receptor-blockers","display_name":"angiotensin receptor blockers","score":0.9919999837875366},{"id":"https://openalex.org/keywords/albuminuria","display_name":"albuminuria","score":0.9409999847412109},{"id":"https://openalex.org/keywords/albumin-creatinine-ratio","display_name":"albumin-creatinine ratio","score":0.9350000023841858},{"id":"https://openalex.org/keywords/urinary-angiotensinogen","display_name":"urinary angiotensinogen","score":0.9570000171661377},{"id":"https://openalex.org/keywords/intrarenal-renin-angiotensin-system","display_name":"intrarenal renin-angiotensin system","score":0.9990000128746033},{"id":"https://openalex.org/keywords/uncontrolled-hypertension","display_name":"uncontrolled hypertension","score":0.8790000081062317},{"id":"https://openalex.org/keywords/blood-pressure-reduction","display_name":"blood pressure reduction","score":0.8399999737739563},{"id":"https://openalex.org/keywords/microalbuminuria","display_name":"microalbuminuria","score":0.8790000081062317},{"id":"https://openalex.org/keywords/central-blood-pressure","display_name":"central blood pressure","score":0.6039999723434448},{"id":"https://openalex.org/keywords/renal-protection","display_name":"renal protection","score":0.6029999852180481},{"id":"https://openalex.org/keywords/albuminuria-regression","display_name":"albuminuria regression","score":0.3269999921321869}],"concepts":[{"id":"https://openalex.org/C2779766728","wikidata":"https://www.wikidata.org/wiki/Q421156","display_name":"Olmesartan","level":3,"score":0.9728022813796997},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7886154651641846},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.6495047807693481},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.643399715423584},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6283996105194092},{"id":"https://openalex.org/C2781203188","wikidata":"https://www.wikidata.org/wiki/Q1676817","display_name":"Microalbuminuria","level":3,"score":0.5816841721534729},{"id":"https://openalex.org/C2776174234","wikidata":"https://www.wikidata.org/wiki/Q974792","display_name":"Albuminuria","level":3,"score":0.5680007338523865},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5489202737808228},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.5053718686103821},{"id":"https://openalex.org/C2908929049","wikidata":"https://www.wikidata.org/wiki/Q65963433","display_name":"Angiotensin II","level":3,"score":0.4412424564361572},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.422693133354187},{"id":"https://openalex.org/C198710026","wikidata":"https://www.wikidata.org/wiki/Q898218","display_name":"Renin\u2013angiotensin system","level":3,"score":0.4210342466831207},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.36069637537002563}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.31871/wjrr.6.1.18","doi":"https://doi.org/10.31871/wjrr.6.1.18","is_oa":true,"landing_page_url":"https://doi.org/10.31871/wjrr.6.1.18","pdf_url":"https://doi.org/10.31871/wjrr.6.1.18","source":{"id":"https://openalex.org/S4306534943","display_name":"World Journal of Research and Review","issn_l":"2455-3956","issn":["2455-3956"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Research and Review","raw_type":"journal-article"},{"id":"pmid:29683146","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29683146","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World journal of research and review","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4835854","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5909402","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5909402","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5909402","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"World J Res Rev","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.31871/wjrr.6.1.18","doi":"https://doi.org/10.31871/wjrr.6.1.18","is_oa":true,"landing_page_url":"https://doi.org/10.31871/wjrr.6.1.18","pdf_url":"https://doi.org/10.31871/wjrr.6.1.18","source":{"id":"https://openalex.org/S4306534943","display_name":"World Journal of Research and Review","issn_l":"2455-3956","issn":["2455-3956"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Research and Review","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.6000000238418579,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[{"id":"https://openalex.org/G1756016309","display_name":"Intrarenal Augmentation of Angiotensinogen by Ang II","funder_award_id":"R01DK072408","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2886228551.pdf","grobid_xml":"https://content.openalex.org/works/W2886228551.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W14430986","https://openalex.org/W1971107230","https://openalex.org/W1974365418","https://openalex.org/W1975291885","https://openalex.org/W1984973770","https://openalex.org/W1985730517","https://openalex.org/W1994259586","https://openalex.org/W2032961459","https://openalex.org/W2044773944","https://openalex.org/W2056976690","https://openalex.org/W2058478385","https://openalex.org/W2073657655","https://openalex.org/W2080670526","https://openalex.org/W2088741159","https://openalex.org/W2092532993","https://openalex.org/W2105397431","https://openalex.org/W2107483107","https://openalex.org/W2110182057","https://openalex.org/W2114614037","https://openalex.org/W2117440871","https://openalex.org/W2141836195","https://openalex.org/W2155329479","https://openalex.org/W2475261460","https://openalex.org/W2544208224","https://openalex.org/W2579827075","https://openalex.org/W2613053395"],"related_works":["https://openalex.org/W2083844058","https://openalex.org/W2613053395","https://openalex.org/W1981687973","https://openalex.org/W2316792032","https://openalex.org/W4381191862","https://openalex.org/W2579827075","https://openalex.org/W2146867458","https://openalex.org/W2361831618","https://openalex.org/W2112439287","https://openalex.org/W3027176978"],"abstract_inverted_index":{"PURPOSE:":[0],"Olmesartan":[1,279],"and":[2,29,50,68,89,104,116,199,232,272,280,286,293,296],"azilsartan":[3,281],"decrease":[4,17],"blood":[5,47,97,101,107,283],"pressure":[6,98,102,108],"more":[7,288],"effectively":[8],"than":[9,240,289],"other":[10,291],"angiotensin":[11],"receptor":[12],"blockers":[13],"(ARBs).":[14],"ARBs":[15,45,83],"additionally":[16],"the":[18,41,139,268,290],"urinary":[19,26,30],"albumin":[20,27],"to":[21,84,155,168,181,192,202],"creatinine":[22],"ratio":[23],"(UACR),":[24],"a":[25],"marker,":[28],"angiotensinogen":[31],"(u-AGT),":[32],"an":[33],"intrarenal":[34],"renin-angiotensin":[35],"system":[36],"activity":[37],"marker.":[38],"We":[39,76],"examined":[40],"effects":[42],"of":[43],"these":[44],"on":[46],"pressure,":[48,284],"UACR,":[49,135,285],"u-AGT":[51,117,137,200,247,271,287],"in":[52,123,131,246,253,270,274],"patients":[53,79,241],"with":[54,59,63,215,251],"uncontrolled":[55,60],"hypertension.":[56],"METHODS:":[57],"Patients":[58,214],"hypertension":[61],"treated":[62],"conventional":[64],"ARBs,":[65,292],"excluding":[66],"olmesartan":[67,86],"azilsartan,":[69,88],"for":[70,92,146],"over":[71],"8":[72],"weeks":[73,122],"were":[74,127,248],"enrolled.":[75],"randomly":[77],"switched":[78],"from":[80],"their":[81],"prior":[82],"either":[85],"or":[87,136,276],"followed":[90],"them":[91],"24":[93,113,121,212],"weeks.":[94,114,213],"RESULTS:":[95],"Systolic":[96],"(SBP),":[99],"diastolic":[100],"(DBP),":[103],"central":[105],"systolic":[106],"(cSBP)":[109],"significantly":[110,209,223,249],"decreased":[111,119,210,282],"at":[112,120,211],"UACR":[115,190,254],"also":[118],"both":[124,144],"groups.":[125,140],"There":[126],"no":[128,264],"significant":[129,265],"differences":[130],"SBP,":[132],"DBP,":[133],"cSBP,":[134],"between":[138,267],"Therefore,":[141],"we":[142],"combined":[143],"groups":[145],"further":[147],"analyses.":[148],"After":[149],"combining,":[150],"SBP":[151,275],"(160.5":[152],"\u00b1":[153,157,166,170,179,183],"16.4":[154],"139.6":[156],"15.6":[158],"mm":[159,172,185],"Hg,":[160,173,186],"P":[161,174,187,196,206,229,237,258],"<":[162,188],"0.0001),":[163,189],"DBP":[164],"(88.4":[165],"13.7":[167],"80.7":[169],"13.2":[171],"=":[175,197,207,230,238,256,259],"0.008),":[176],"cSBP":[177],"(167.4":[178],"20.8":[180],"146.6":[182],"24.6":[184],"(13.8":[191],"9.0":[193],"mg/g":[194,220],"Cre,":[195,205],"0.0096),":[198],"(4.13":[201],"2.32":[203],"\u03bcg/g":[204],"0.0074)":[208],"microalbuminuria":[216],"(UACR":[217],"\u2265":[218],"30":[219],"Cre)":[221],"had":[222],"greater":[224],"\u0394UACR":[225],"(-39.4":[226],"vs":[227,235],"0.27,":[228],"0.0024)":[231],"\u0394u-AGT":[233],"(-11.9":[234],"-0.61,":[236],"0.0235)":[239],"without":[242],"microalbuminuria.":[243],"The":[244],"changes":[245,252,269],"associated":[250],"(r":[255],"0.411,":[257],"0.046);":[260],"however,":[261],"there":[262],"was":[263],"relationship":[266],"those":[273],"DBP.":[277],"CONCLUSION:":[278],"exerted":[294],"depressor":[295],"renoprotective":[297],"effects.":[298]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2018-08-22T00:00:00"}
